Our widgets for functional genomics use Orange, a data mining
and machine learning suite. Orange can be accessed through scripting in
Python,
or by visual programming in Orange Canvas.
In functional genomics, we have also designed a web-based tool for mutant data analysis called GenePath (also featured
in Science's NetWatch).
We have designed a schema in which two "Scatter Plot" widgets are first used
to isolate the genes whose expression is specifically induced in the M/G1
phase of the cell cycle, as shown in "Expression
Profiles (2)" and "Heat Map"
widgets. "Genome Map" widget is used to
demonstrate the adjacent positioning of coexpressed genes, as described in Cho
et al. (1998). "GO Term Finder"
widget is used to show that two adjacent coexpressed genes, CDC46 and PIG1 are
functionally unrelated, and the "GO
Term Finder (2)" widget is used to show the GO biological_process
categories of the 800 input genes.
Clicking on a widget icon in the schema displays a snapshot of the widget
during analysis. Please wait for the "GO
Term Finder (2)" widget to finish before exploring data in other
widgets.