Data set name: GSE2191

Brief description:

The classification problem this dataset addresses is distinguishing patients with acute myeloid leukemia (AML) according to their prognosis after treatment (remission or relapse of disease). Most of the patients enter complete remission after treatment, but a significant number of them experience relapse with resistant disease.

Platform: Affymetrix GeneChip Human Genome U95 Version [1 or 2] Set HG-U95A

Diagnostic classes:

- remission (remission): 28 examples (51.9%)

- relapse (relapse): 26 examples (48.1%)

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):

Classification accuracy: 72.00%

Area under curve (AUC): 0.781

	Score: 89.88% Genes: 36902_at: ras homolog gene family, member G (rho G), RHOG 39105_at: vasodilator-stimulated phosphoprotein, VASP 36648_at: cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa, CRSP9 1718_at: actin related protein 2/3 complex, subunit 2, 34kDa, ARPC2 38622_at: GTP_binding protein, GTP 40709_at: zinc finger protein 271, ZNF271 36330_at: cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), CCBL1 35177_at: DDHD domain containing 2, DDHD2
	Score: 87.08% Genes: 38789_at: transketolase (Wernicke-Korsakoff syndrome), TKT 39758_f_at: lysosomal-associated membrane protein 1, LAMP1 39105_at: vasodilator-stimulated phosphoprotein, VASP 32215_i_at: Rho-related BTB domain containing 3, RHOBTB3 40709_at: zinc finger protein 271, ZNF271 36330_at: cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), CCBL1
	Score: 84.65% Genes: 36372_at: hexokinase 3 (white cell), HK3 39758_f_at: lysosomal-associated membrane protein 1, LAMP1 40709_at: zinc finger protein 271, ZNF271 32215_i_at: Rho-related BTB domain containing 3, RHOBTB3

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes: 40709_at: zinc finger protein 271, ZNF271 39758_f_at: lysosomal-associated membrane protein 1, LAMP1 38789_at: transketolase (Wernicke-Korsakoff syndrome), TKT 39105_at: vasodilator-stimulated phosphoprotein, VASP 32215_i_at: Rho-related BTB domain containing 3, RHOBTB3 36330_at: cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), CCBL1 36902_at: ras homolog gene family, member G (rho G), RHOG 38470_i_at: amyloid beta precursor protein (cytoplasmic tail) binding protein 2, APPBP2 33390_at: Serine/threonine kinase 17b (apoptosis-inducing), STK17B 40861_at: mortality factor 4 like 2, MORF4L2 1195_s_at: integrin beta 1 binding protein 1, ITGB1BP1 35820_at: GM2 ganglioside activator, GM2A 1718_at: actin related protein 2/3 complex, subunit 2, 34kDa, ARPC2 38622_at: GTP_binding protein, GTP 37190_at: WAS protein family, member 1, WASF1 40878_f_at: D15F37 gene /// hypothetical LOC440248, D15F37 /// LOC440248 36338_at: leucine zipper protein 1, LUZP1 35177_at: DDHD domain containing 2, DDHD2 36963_at: phosphogluconate dehydrogenase, PGD 36590_at: solute carrier family 16 (monocarboxylic acid transporters), member 2, SLC16A2