Data set name: GSE2191


Original data set (GSE2191)
Data set for Orange
Brief description:
The classification problem this dataset addresses is distinguishing patients with acute myeloid leukemia (AML) according to their prognosis after treatment (remission or relapse of disease). Most of the patients enter complete remission after treatment, but a significant number of them experience relapse with resistant disease.

Platform: Affymetrix GeneChip Human Genome U95 Version [1 or 2] Set HG-U95A

Diagnostic classes:
- remission (remission): 28 examples (51.9%)
- relapse (relapse): 26 examples (48.1%)
Number of genes: 12625
Number of samples: 54
Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):
Classification accuracy: 72.00%
Area under curve (AUC): 0.781
Following are the three best-ranked visualization with eight, six and four attributes in respect to the visualization score, that is, visualizations where examples from different diagnostic classes are best separated:

Score: 89.88%
Genes:
36902_at: ras homolog gene family, member G (rho G), RHOG
39105_at: vasodilator-stimulated phosphoprotein, VASP
36648_at: cofactor required for Sp1 transcriptional activation, subunit 9, 33kDa, CRSP9
1718_at: actin related protein 2/3 complex, subunit 2, 34kDa, ARPC2
38622_at: GTP_binding protein, GTP
40709_at: zinc finger protein 271, ZNF271
36330_at: cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), CCBL1
35177_at: DDHD domain containing 2, DDHD2
Score: 87.08%
Genes:
38789_at: transketolase (Wernicke-Korsakoff syndrome), TKT
39758_f_at: lysosomal-associated membrane protein 1, LAMP1
39105_at: vasodilator-stimulated phosphoprotein, VASP
32215_i_at: Rho-related BTB domain containing 3, RHOBTB3
40709_at: zinc finger protein 271, ZNF271
36330_at: cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), CCBL1
Score: 84.65%
Genes:
36372_at: hexokinase 3 (white cell), HK3
39758_f_at: lysosomal-associated membrane protein 1, LAMP1
40709_at: zinc finger protein 271, ZNF271
32215_i_at: Rho-related BTB domain containing 3, RHOBTB3

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes:
40709_at: zinc finger protein 271, ZNF271
39758_f_at: lysosomal-associated membrane protein 1, LAMP1
38789_at: transketolase (Wernicke-Korsakoff syndrome), TKT
39105_at: vasodilator-stimulated phosphoprotein, VASP
32215_i_at: Rho-related BTB domain containing 3, RHOBTB3
36330_at: cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase), CCBL1
36902_at: ras homolog gene family, member G (rho G), RHOG
38470_i_at: amyloid beta precursor protein (cytoplasmic tail) binding protein 2, APPBP2
33390_at: Serine/threonine kinase 17b (apoptosis-inducing), STK17B
40861_at: mortality factor 4 like 2, MORF4L2
1195_s_at: integrin beta 1 binding protein 1, ITGB1BP1
35820_at: GM2 ganglioside activator, GM2A
1718_at: actin related protein 2/3 complex, subunit 2, 34kDa, ARPC2
38622_at: GTP_binding protein, GTP
37190_at: WAS protein family, member 1, WASF1
40878_f_at: D15F37 gene /// hypothetical LOC440248, D15F37 /// LOC440248
36338_at: leucine zipper protein 1, LUZP1
35177_at: DDHD domain containing 2, DDHD2
36963_at: phosphogluconate dehydrogenase, PGD
36590_at: solute carrier family 16 (monocarboxylic acid transporters), member 2, SLC16A2