Data set name: GSE2379

Brief description:

For this data set we induced models for two different classification problems. With the first model we are simply trying to distinguish between normal tissue samples from the head and neck region and hypopharyngeal cancer samples.

Platform: Affymetrix GeneChip Human Genome U95 Version [1 or 2] Set HG-U95A

Diagnostic classes:

- hypopharyngeal cancer (T): 34 examples (89.5%)

- normal tissue (N): 4 examples (10.5%)

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):

Classification accuracy: 90.00%

Area under curve (AUC): 0.691

	Score: 100.00% Genes: 160042_s_at: homeo box B6, HOXB6 160041_at: protein tyrosine phosphatase, non-receptor type 18 (brain-derived), PTPN18 160024_at: cyclin-dependent kinase (CDC2-like) 10, CDK10 160020_at: matrix metalloproteinase 14 (membrane-inserted), MMP14 37762_at: epithelial membrane protein 1, EMP1 38051_at: mal, T-cell differentiation protein, MAL 37920_at: paired-like homeodomain transcription factor 1, PITX1 36569_at: C-type lectin domain family 3, member B, CLEC3B
	Score: 100.00% Genes: 39333_at: collagen, type IV, alpha 1, COL4A1 160044_g_at: aconitase 2, mitochondrial, ACO2 160026_at: protein kinase, X-linked, PRKX 37762_at: epithelial membrane protein 1, EMP1 36890_at: periplakin, PPL 36569_at: C-type lectin domain family 3, member B, CLEC3B
	Score: 100.00% Genes: 160029_at: protein kinase C, beta 1, PRKCB1 160027_s_at: insulin-like growth factor 2 receptor, IGF2R 36890_at: periplakin, PPL 36569_at: C-type lectin domain family 3, member B, CLEC3B

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes: 160041_at: protein tyrosine phosphatase, non-receptor type 18 (brain-derived), PTPN18 160027_s_at: insulin-like growth factor 2 receptor, IGF2R 36569_at: C-type lectin domain family 3, member B, CLEC3B 37762_at: epithelial membrane protein 1, EMP1 36290_s_at: fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group included) /// fucosyltransferase 5 (alpha (1,3) fucosyltransferase) /// fucosyltransferase 6 (alpha (1,3) fucosyltransferase), FUT3 /// FUT5 /// FUT6 160020_at: matrix metalloproteinase 14 (membrane-inserted), MMP14 36890_at: periplakin, PPL 160033_s_at: X-ray repair complementing defective repair in Chinese hamster cells 1, XRCC1 36289_f_at: fucosyltransferase 6 (alpha (1,3) fucosyltransferase), FUT6 160032_at: interleukin 6 receptor, IL6R 160044_g_at: aconitase 2, mitochondrial, ACO2 32868_at: transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase), TGM3 38098_at: lipin 1, LPIN1 160042_s_at: homeo box B6, HOXB6 160024_at: cyclin-dependent kinase (CDC2-like) 10, CDK10 40315_at: serine protease inhibitor, Kazal type 5, SPINK5 38051_at: mal, T-cell differentiation protein, MAL 37920_at: paired-like homeodomain transcription factor 1, PITX1 160029_at: protein kinase C, beta 1, PRKCB1 31343_at: interleukin 1 receptor antagonist, IL1RN