Data set name: GSE2685

Brief description:

For this data set we induced models for two different classification problems. With the first model we are trying to distinguish between diffuse and intestinal tumor gastric samples and normal gastric tissue.

Platform: Affymetrix GeneChip Human Full Length Array HuGeneFL

Diagnostic classes:

- normal gastric tissue (Normal): 8 examples (26.7%)

- diffuse gastric tumor (Diffuse): 5 examples (16.7%)

- intestinal gastric tumor (Intestinal): 17 examples (56.7%)

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):

Classification accuracy: 60.00%

Area under curve (AUC): 0.762

	Score: 99.57% Genes: D26129_at: ribonuclease, RNase A family, 1 (pancreatic), RNASE1 U66052_at: Iduronate 2-sulfatase (Hunter syndrome), IDS X83416_s_at: prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia), PRNP U46006_s_at: cysteine and glycine-rich protein 2, CSRP2 U03105_at: proline-rich nuclear receptor coactivator 1, PNRC1 U50360_s_at: calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma, CAMK2G X81817_at: B-cell receptor-associated protein 31, BCAP31 U07969_s_at: cadherin 17, LI cadherin (liver-intestine), CDH17
	Score: 98.99% Genes: M62628_s_at: Hypothetical protein MGC27165, MGC27165 D87742_at: C219-reactive peptide /// AAAP6077 /// similar to C219-reactive peptide, KIAA0268 /// UNQ6077 /// LOC440751 U86755_s_at: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), ADAM17 U03105_at: proline-rich nuclear receptor coactivator 1, PNRC1 U95040_at: tripartite motif-containing 28, TRIM28 D78132_s_at: Ras homolog enriched in brain, RHEB
	Score: 95.38% Genes: AC002077_at: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1, GNAT1 X05409_at: aldehyde dehydrogenase 2 family (mitochondrial), ALDH2 X83416_s_at: prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia), PRNP U26424_at: serine/threonine kinase 3 (STE20 homolog, yeast), STK3

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes: X83416_s_at: prion protein (p27-30) (Creutzfeld-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia), PRNP U26424_at: serine/threonine kinase 3 (STE20 homolog, yeast), STK3 X05409_at: aldehyde dehydrogenase 2 family (mitochondrial), ALDH2 M62628_s_at: Hypothetical protein MGC27165, MGC27165 U21931_at: fructose-1,6-bisphosphatase 1, FBP1 X81817_at: B-cell receptor-associated protein 31, BCAP31 D26129_at: ribonuclease, RNase A family, 1 (pancreatic), RNASE1 U03105_at: proline-rich nuclear receptor coactivator 1, PNRC1 U86755_s_at: a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), ADAM17 S68616_at: solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive), SLC9A1 L41939_at: EPH receptor B2, EPHB2 U66469_at: cell growth regulator with ring finger domain 1, CGRRF1 X66839_at: carbonic anhydrase IX, CA9 U19948_at: protein disulfide isomerase family A, member 2, PDIA2 U70663_at: Kruppel-like factor 4 (gut), KLF4 M63154_at: gastric intrinsic factor (vitamin B synthesis), GIF U07969_s_at: cadherin 17, LI cadherin (liver-intestine), CDH17 AC002077_at: guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1, GNAT1 V00572_at: phosphoglycerate kinase 1, PGK1 X96752_at: L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain, HADHSC