FRI > Biolab > Supplements

Data set name: SRBCT


Original data set (Khan et al.)
Data set for Orange
Brief description:
The small round blue cell tumors (SRBCTs) are 4 different childhood tumors named so because of their similar appearance on routine histology, which makes correct clinical diagnosis extremely challenging. However, accurate diagnosis is essential because the treatment options, responses to therapy and prognoses vary widely depending on the diagnosis. They include Ewing's family of tumors (EWS), neuroblastoma (NB), non-Hodgkin lymphoma (in our case Burkitt's lymphoma, BL) and rhabdomyosarcoma (RMS). Our classification model was built to distinguish between these four tumors based on gene expression values.

Platform: cDNA microarrays

Diagnostic classes:
- Ewing's sarcoma (EWS): 29 examples (34.9%)
- Burkitt's lymphoma (BL): 11 examples (13.3%)
- neuroblastoma (NB): 18 examples (21.7%)
- rhabdomyosarcoma (RMS): 25 examples (30.1%)
Number of genes: 2308
Number of samples: 83
Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):
Classification accuracy: 97.78%
Area under curve (AUC): 1.000
Following are the three best-ranked visualization with eight, six and four attributes in respect to the visualization score, that is, visualizations where examples from different diagnostic classes are best separated:

Score: 99.90%
Genes:
770394: None, None
814260: None, None
624360: None, None
80109: None, None
812105: None, None
325182: None, None
207274: None, None
796258: None, None
Score: 99.28%
Genes:
866702: None, None
377461: None, None
236282: None, None
796258: None, None
143306: None, None
812105: None, None
Score: 98.44%
Genes:
814260: None, None
629896: None, None
796258: None, None
183337: None, None

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes:
812105: None, None
796258: None, None
770394: None, None
207274: None, None
183337: None, None
629896: None, None
1435862: None, None
624360: None, None
325182: None, None
236282: None, None
377461: None, None
767183: None, None
80109: None, None
866702: None, None
296448: None, None
814260: None, None
745019: None, None
244618: None, None
80338: None, None
1469292: None, None