Data set name: GSE1577

Brief description:

Additional B-precursor acute lymphoblastic leukemia (B-ALL) bone marrow samples were added as a new diagnostic class. This model now contains samples from three diagnostic classes (T-ALL, T-LL and B-ALL).

Platform: Affymetrix GeneChip Human Genome U133 Array Set HG-U133A

Diagnostic classes:

- T-cell lymphoblastic lymphoma (T-LL): 9 examples (31.0%)

- T-cell acute lymphoblastic leukemia (T-ALL): 10 examples (34.5%)

- B-cell acute lymphoblastic leukemia (B-ALL): 10 examples (34.5%)

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):

Classification accuracy: 86.67%

Area under curve (AUC): 0.946

	Score: 99.98% Genes: 202112_at: von Willebrand factor, VWF 209121_x_at: nuclear receptor subfamily 2, group F, member 2, NR2F2 209120_at: nuclear receptor subfamily 2, group F, member 2, NR2F2 210788_s_at: dehydrogenase/reductase (SDR family) member 7, DHRS7 210715_s_at: serine protease inhibitor, Kunitz type, 2, SPINT2 209009_at: esterase D/formylglutathione hydrolase, ESD 203380_x_at: splicing factor, arginine/serine-rich 5, SFRS5 200092_s_at: ribosomal protein L37 /// ribosomal protein L37, RPL37
	Score: 99.98% Genes: 202112_at: von Willebrand factor, VWF 204570_at: cytochrome c oxidase subunit VIIa polypeptide 1 (muscle), COX7A1 210788_s_at: dehydrogenase/reductase (SDR family) member 7, DHRS7 210715_s_at: serine protease inhibitor, Kunitz type, 2, SPINT2 200092_s_at: ribosomal protein L37 /// ribosomal protein L37, RPL37 203380_x_at: splicing factor, arginine/serine-rich 5, SFRS5
	Score: 99.98% Genes: 217757_at: alpha-2-macroglobulin, A2M 209120_at: nuclear receptor subfamily 2, group F, member 2, NR2F2 202207_at: ADP-ribosylation factor-like 7, ARL7 203380_x_at: splicing factor, arginine/serine-rich 5, SFRS5

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes: 203380_x_at: splicing factor, arginine/serine-rich 5, SFRS5 209120_at: nuclear receptor subfamily 2, group F, member 2, NR2F2 202112_at: von Willebrand factor, VWF 217717_s_at: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, YWHAB 209121_x_at: nuclear receptor subfamily 2, group F, member 2, NR2F2 209290_s_at: nuclear factor I/B, NFIB 217757_at: alpha-2-macroglobulin, A2M 201339_s_at: sterol carrier protein 2, SCP2 202131_s_at: RIO kinase 3 (yeast) /// RIO kinase 3 (yeast), RIOK3 217627_at: zinc finger protein 573, ZNF573 203492_x_at: translokin, PIG8 210715_s_at: serine protease inhibitor, Kunitz type, 2, SPINT2 204570_at: cytochrome c oxidase subunit VIIa polypeptide 1 (muscle), COX7A1 201226_at: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa, NDUFB8 202207_at: ADP-ribosylation factor-like 7, ARL7 210788_s_at: dehydrogenase/reductase (SDR family) member 7, DHRS7 200092_s_at: ribosomal protein L37 /// ribosomal protein L37, RPL37 218204_s_at: FYVE and coiled-coil domain containing 1, FYCO1 206702_at: TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal), TEK 202713_s_at: KIAA0391, KIAA0391