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Data set name: GSE967

Original data set (GSE967)
Data set for Orange

Brief description:: With this model we are trying to distinguish between two childhood tumors - Ewing's sarcoma (EWS) and rhabdomyosarcoma (RMS) based on gene expression values.

Platform: Affymetrix GeneChip Human Genome U95 Version [1 or 2] Set HG-U95A

Diagnostic classes:: - Ewing's sarcoma (EWS): 11 examples (47.8%); - Rhabdomyosarcoma (RMS): 12 examples (52.2%)

Number of genes: 9945
Number of samples: 23
Note: From the originally measured 12625 probe sets we removed genes that were not present (P) in at least one sample

Predictive accuracy with 10-fold cross validation (classifying using the best projection with eight attributes):: Classification accuracy: 95.00%; Area under curve (AUC): 1.000

Following are the three best-ranked visualization with eight, six and four attributes in respect to the visualization score, that is, visualizations where examples from different diagnostic classes are best separated:

	Score: 99.98% Genes: 39721_at: ephrin-B1, EFNB1 34877_at: Janus kinase 1 (a protein tyrosine kinase), JAK1 41138_at: CD99 antigen, CD99 33292_at: dynein, axonemal, light polypeptide 4, DNAL4 39350_at: glypican 3, GPC3 40570_at: forkhead box O1A (rhabdomyosarcoma), FOXO1A 1664_at 33929_at: glypican 1, GPC1
	Score: 99.98% Genes: 39721_at: ephrin-B1, EFNB1 41138_at: CD99 antigen, CD99 40607_at: dihydropyrimidinase-like 2, DPYSL2 38486_at: troponin I, skeletal, slow, TNNI1 1664_at 1296_at: cadherin 15, M-cadherin (myotubule), CDH15
	Score: 99.97% Genes: 33292_at: dynein, axonemal, light polypeptide 4, DNAL4 41138_at: CD99 antigen, CD99 39063_at: actin, alpha, cardiac muscle, ACTC 39350_at: glypican 3, GPC3

Attribute ranking

Following is the histogram of genes showing how often are they present in one of the top 100 radviz visualizations with 8 attributes.

Genes:
39350_at: glypican 3, GPC3
41138_at: CD99 antigen, CD99
1664_at
39063_at: actin, alpha, cardiac muscle, ACTC
31432_g_at: Fc fragment of IgG, receptor, transporter, alpha, FCGRT
36119_at: caveolin 1, caveolae protein, 22kDa, CAV1
34198_at: protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase), PTPN13
41215_s_at: inhibitor of DNA binding 2, dominant negative helix-loop-helix protein /// inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein, ID2 /// ID2B
39721_at: ephrin-B1, EFNB1
37749_at: mesoderm specific transcript homolog (mouse), MEST
40570_at: forkhead box O1A (rhabdomyosarcoma), FOXO1A
38486_at: troponin I, skeletal, slow, TNNI1
41289_at: neural cell adhesion molecule 1, NCAM1
33192_g_at: chromosome 10 open reading frame 6, C10orf6
35330_at: filamin C, gamma (actin binding protein 280), FLNC
35321_at: tousled-like kinase 2, TLK2
215_g_at: msh homeo box homolog 1 (Drosophila), MSX1
1296_at: cadherin 15, M-cadherin (myotubule), CDH15
33292_at: dynein, axonemal, light polypeptide 4, DNAL4