Introduction 1 5 6 7 8 9 10 11 12 7 118 7 13 7 13 14 q 2 3 3 2+ 2+ 1 2 4 6 11 12 13 14 1–7 15 7 2+ 5 16 in vitro 7 in vivo 17 18 2+ 2+ 5 19 2 20 21 2+ 5 13 2+ 2+ Materials and methods Reagents O 2+ o N,N,N′,N′ Cell culture 22 7 2+ 2 2 2 2 23 5 7 13 7 5 2+ 2+ F \documentclass[12pt]{minimal}
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$$Percentchangeinaveragefluorescence = {{(F - F0)} \over {F0}} \times 100$$
\end{document} F 0 5 7 Migration assay 7 13 2 2 Statistical analysis t P 50 F max \documentclass[12pt]{minimal}
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$$F = {{{F_{max}} \times [L]} \over {E{C_{50}} + [L]}}$$
\end{document} F L Results Nucleotide dose response curves 2+ −7 −3 1 −4 2+ 50 −6 −6 50 −4 −4 50 −5 Figure 1 2+  2+ 2+ Role of nucleotides in injury response 2a 2b 2c 2c 5 2b 2d 2b 2d white circle 2d 2+ Figure 2 2+ 2+ red 2+ blue 2+ horizontal white bar 2+ asterisk 2+ asterisk  2e 2f 2g 2f 2h 2a d 2f 2g 2+ 2f 2h 2+ 5 5 Figure 5 2+ red 2+ 2+ horizontal white bar 2+ asterisk 2+ asterisk www.springeronline.com  2+ 3 4 3 2+ 4 Figure 3 2+ 2+ red 2+ blue 2+ horizontal white bar 2+ asterisk www.springeronline.com  Figure 4 2+ 2+ red 2+ 2+ horizontal white bar 2+ asterisk www.springeronline.com  5a 5d 3 4 2+ 5a 5d 5 2+ 2+ 2+ 5e 5f 5g 5f 5h 2 2+ 2+ 5e 5h 2+ 6a 2+ 6a Figure 6 2+ t P  6b 2+ Nucleotides and EGF induce cell migration 7 7 7 7a b 7 7c d 2 2 7e Figure 7 2  5 8a 24 2 2 8b 2 8b 7 8c 2 2 2 2 Figure 8 2  2 20 6 4 18 9 2 9 Figure 9 2 t P  Discussion 2+ 5 13 2+ 2 3 25 2+ 1 2+ 6 13 2+ 7 1 6 7 2+ 5 5 2+ 2+ 5 2+ 26 V 3 2+ 2 20 9 13 2 1 2+ 27 7 2+ 28 7 29 2 30 7 13 21 31 32 33 34 21 31 35 36 7 2+ 3 6 2+ 7 7 13 28 29 37 2+ 2+ 7 10 2 4