Introduction 1 2 n n n n n Discussion Classification foregut midgut hindgut 3 4 functional nonfunctional Imaging approach 5 Anatomic imaging Multidetector CT 6 7 1 8 Fig. 1 a arrows b  MRI 9 2 10 Fig. 2 a b c d  Sonography 9 11 3 12 Fig. 3 arrow V  Molecular imaging 13 111 4 14 14 Fig. 4 2 a arrowhead arrow arrow b c brown  5 18 15 18 16 Fig. 5 a b  Fusion imaging 6 7 17 Fig. 6 a arrow b  Fig. 7 a b arrow arrowhead  Common pediatric GEP-NETs by location Appendiceal NETs 2 8 18 20 21 18 20 18 21 2 18 Fig. 8 a arrow b arrow  Gastrointestinal NETs 22 23 8 Hepatic NETs 1 Pancreatic NETs 24 25 24 9 Fig. 9 a b arrow arrowhead c d  Pulmonary NETs 1 1 26 27 28 27 10 10 29 30 Fig. 10 a b arrow c arrow arrowhead  Thymic NETs 9 31 11 Fig. 11 a b arrow c d e f e f  Middle ear NETs 12 32 Fig. 12 a b  Conclusions A low index of suspicion for GEP-NETs in children combined with nonspecific clinical complaints can result in delay in the detection of these rare but treatable malignancies. A multimodality imaging approach using both anatomic and functional imaging is essential in the diagnosis, staging, and surveillance of these potentially malignant tumors in children.