Introduction 1 2 4 5 6 7 9 10 11 5 TD 12 Materials and methods 2 A4-Fthermodilutioncatheter(PulsiocathPV2014 L16) was introduced into the femoral artery and connected to a commercially available CO device (PiCCO, Pulsion,Munich, Germany). Transpulmonary thermodilution cardiac output (TPCO) was measured by quadruple injections of 15 ml ice-cold saline into the right atrium and used for transpulmonary thermodilution stroke volume calculation. 13 14 15 t 1 t 2 t 3 t 4 t 5 t 6 t 7 16 t TD 17 15 TD p Results 2 1 TD K 2 2 TD SB 2 2 TD W 2 2 1 Fig. 1 SVI SVI TD SVI K 13 SVI SB 14 SVI W 15 p t 1  Table 1 LOA SVI TD t 1 t 2 t 3 t 4 t 5 t 6 t 7 SVI K 13 SVI SB 14 SVI W 15  K SB W time  Bias (ml/m–2)  Precision (ml/m–2)  LOA (ml/m–2)  Mean error (%)  Bias (ml/m–2)  Precision (ml/m–2)  LOA (ml/m–2)  Mean error (%)  Bias (ml/m–2)  Precision (ml/m–2)  LOA (ml/m–2)  Mean error (%) t 1 6.4 13.9 –20.8, +33.6 77 15.5 12.3 –8.6, +39.6 68 –14.7 9.8 –33.9, +4.5 54 t 2 0.6 8.8 –16.6, +17.8 51 11.8 9.3 –6.4, +30.0 54 –13.0 4.8 –22.5,– 3.5 28 t 3 –3.0 7.8 –18.3, +12.4 51 6.2 13.9 –21.0, +33.4 90 –14.2 8.1 –30.2, +1.7 53 t 4 1.0 8.4 –15.5, +17.6 56 9.9 5.4 –0.7, +20.4 36 –13.8 5.8 –25.1,– 2.5 38 t 5 0.4 10.0 –19.2, +20.0 58 10.1 10.7 –10.9, +31.1 62 –16.3 8.6 –33.1, +0.6 50 t 6 1.5 13.3 –24.5, +27.5 73 7.2 12.1 –16.4, +30.9 66 –17.8 9.5 –36.4, +0.8 52 t 7 –0.6 10.7 –21.5, +20.4 60 8.3 13.0 –17.2, +33.8 72 –18.0 8.1 –34.0, –2.1 45 Discussion TD TD 18 TD 19 8 9 8 t 2 TD 20 Electronic supplementary material Electronic Supplementary Material (DOC 54K)