Introduction and Characterization of Prostatitis 1 2 3 Category 1. Acute bacterial prostatitis Category 2. Chronic bacterial prostatitis A. Inflammatory B. Non-inflammatory Category 4. Asymptomatic inflammatory prostatitis. While most patients report a primary subjective symptom of local pain and/or dysuria, the clinical presentation of acute versus chronic prostatitis varies. Laboratory cultures are standardly employed to detect bacterial involvement and this testing along with other diagnostic criteria determines each classification. Men with Category 1, acute prostatitis, frequently present with dysuria, fever, malaise, myalgia (non-specific) and positive culture analysis that often reveals coliform bacteria. This imparts to standard antibiotic treatment with good prognosis for recovery and minimal recurrence. 2 1 1 4 4 5 Table 1 2 3 3 3 6 1 4 5 7 8 CAM Background 9 9 8 10 11 10 CAM Therapies for CP/CPPS Biofeedback 12 17 13 15 P 13 P 15 Acupuncture 18 19 20 23 24 25 26 P 27 27 P P 28 High Frequency Electrostimulation P 29 Hyperthermia 30 30 31 32 33 Herbal and Nutritional Supplements 34 40 Fig. 1 Saw palmetto Serenoa repens S. repens 41 in vitro 34 39 42 44 P P 42 43 44 The assessments of saw palmetto studies for CP/CPPS are far fewer than those for BPH. However, marked and continued progress in molecular studies, increased mechanistic data and more clinical trials in CP/CPPS are warranted to ascertain the utility and reproducibility of saw palmetto use in men with chronic prostatitis. Pollen Extract: Cernilton 41 41 45 46 In vitro 47 48 45 48 52 ® 53 Quercetin 41 54 56 P 57 Other Herbal Agents for Prostatitis Rheum palmatum Rx. astragalus memberanaceus Flos Chrysanthemi Indici 58 62 in vitro 58 Conclusions Table 2 in vitro 63 64