Background 1 2 3 4 5 Methodology Database model and content 6 7 figure 1 Searching DND There are three ways by which the user can query the database. The first one is the keyword search in home page that can be performed by giving keywords like Disease name, Gene name and Drug name to retrieve the required data. The second one is the advanced search option for specific requirements with two main entry points namely gene/protein and drug/drug properties. Gene/protein include search options like Gene name, Gene id, Omim, Hgnc, Pubmed, Swissprot id, Pdb, Interpro, Pfam, Smart and Prints. The second entry point Drug/drug properties include Drug name, Kegg id, DrugBank id, Pubchem, and IUPAC name and Molecular formula. Alternatively, the users can also browse the database via the seven entry points namely browse by Diseases, Genes, Proteins, Drugs, Pathways, Related Articles and Organizations. Utility 8