Background 1 2 3 4 Methodology Nucleic Acids Research 5 4 6 7 First, we have developed a user interface to search databases globally. In other words, a global search can be utilized to search the categories reported in DoD2007, database names and other pages located in 
the database. Keywords used to search the database can be general or specific and depends on the terms indexed for search.  Second, an organized category list was created in a separate page. The availability of these databases as a list is intended to promote better understanding of database segregation used to generate 
categories and to quickly recognize the new ones with those that are inaccessible. These databases have links to the database entries because a link back to the main page makes it easy for both new and 
proficient users to conduct a variety of searches. However, some users may not realize the keywords that need to be used to search a database and even some users may show interest in the published resource. 
Hence, a keyword help and links to abstract or full-text articles were created in respective main pages for intuitive and efficient presentation. Finally, a number of sub-categories are created such 
as ‘Operons’ and ‘Comparative genomics’ in ‘nucleotide db’ and ‘Genomics db’ respectively along with two sub-categories viz. ‘Protein Interactions’ and ‘Amino Acid Repeats’ in ‘Protein Sequence db’. Features of DoD2007 DoD2007 is a unique, categorized and easy-to-use interface for all molecular biology databases. New databases in various categories were appended and the number of databases in DOD2007 reached up to 1082 that are 209 databases ahead 
from the previous issue. Major additions, 49 new entries, were reported in Genomics database. However, the list is not complete. A brief description of databases under all categories was given as a pop-up window with a provision to view 
full-text of the published article and a direct link to the database home page. The search option under ‘link to database’ leads to the respective home pages of the database. Boolean search items are not allowed in the DoD2007 but spaces 
between search strings enables the search. During the search, results are displayed in a separate window as this helps in further database scan without losing the home page. supplementary material figure 1 8 9 10 figure 2 Utility DoD2007 provides the updated descriptions and links to existing and new databases that serves as an interface and user-friendly access to molecular biology scientific community. Number of inaccessible databases reported in the 
years 2005 and 2006 remain unchanged in DoD2007 so as to enable the users to know the type of database that once existed.  Conclusion DoD2007, a freely available web-based database resource enabling ease of access, serves as a general reference source both for community of researchers working in molecular biology and educators who deal with particular databases 
of their interest. Brief description about the databases and keyword help makes the users familiar with the contents of the database, respective keywords and database links. The database shall be updated on a yearly basis. Supplementary material Data 1