Background 1 2 3 4 5 6 7 8 2 2 9 MetaSample MetaChip CIAeasy http://systemsanalysis.louisville.edu Methodology Dataset collections 9 Tracking provenance 10 11 12 13 14 15 2 Data integration MetaSample MetaChip CIAeasy Figure 1 MetaSample MetaChip MetaChip 2 16 MetaSample MetaChip CIAeasy CIAeasy R 17 18 CIAeasy R 18 CIAeasy Data analysis 2 19 Discussion Implementation of QueryBDSM 10 Figure 2 http://www.genome.ad.jp/kegg/ Table 1 P MetaChip CIAeasy MetaChip Table 1 CIAeasy MetaSample Figure 2 Table 1 Comparative bioinformatics analysis across developing systems 6 Figure 3 2 MetaSample MetaChip Continue 20 MetaSample MetaChip Conclusion The representation of experimental samples as developmentally contiguous groups is expected to yield a novel mosaic view of gene-expression signatures and genetic dependencies. Although
sufficient data exists for data-mining efforts to begin, the ultimate goal of an unabridged reference collection must be viewed as a long-term effort. Regarding the embryo, a search of
OVID MedLine using keywords ‘embryo’ OR ‘teratogen’ (136,146 records) AND ‘microarray’ OR ‘SAGE’ (16,906 records) returned 343 total records. At the current rate of 564
microarrays per 343 publication records (factor = 1.64), the trajectory of embryo-based microarray publications projects GEO to hold in excess of 1,476 microarrays relevant for
embryogenesis or teratogenesis by the year 2010. 2 http://www.oncomine.org/ 21