Introduction d 2 2 1 1 4 5 6 7 8 7 9 10 11 12 Experimental Materials Aspergillus niger −1 −1 −1 −1 Design of the microreactors 1 12 Fig. 1 a b  Set-up of the system 13 15 GOx/HRP activity monitoring −1 −1 −1 Preparation of apoGOx and restoration of the enzyme activity 16 −1 −1 −1 v v −1 −1 −1 −1 −1 −1 Determination of several characteristics of the miniaturized enzyme reactor 1 1 \documentclass[12pt]{minimal}
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\begin{document}$$ {\text{\% conversion}} = \frac{{{\sqrt {{\left( {2\pi } \right)}} }h\sigma 100\% }} {{IcnF}} $$\end{document} h σ I c −1 n F −1 π σ 1 Results Preparation of apoGOx and restoration of the enzyme activity 2 2 2 \documentclass[12pt]{minimal}
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\begin{document}$$ {\text{f}}{\left( {\text{t}} \right)} = {\text{1}} - {\text{exp}}{\left( { - {\text{kt}}} \right)} $$\end{document} k −1 t Fig. 2 circles solid line f t t  1 2 Performance 3 3 1 Fig. 3 a diamonds squares triangles circles stars b circles −1 squares −1 triangles −1 diamonds −1  Table 1 Measured detector signal and relative conversion of glucose in relation to the amount of enzyme retained on the filter in the miniaturized microreactor. Indicated are the amounts of GOx (in fmol) on the PES filter and the signals of the detector (in nA) indicating the amount of converted glucose, calculated as described in the method section Protein (GOx) on the filter (fmol) Signal (nA) Conversion (%) 0.0625 0.016 0.04 0.625 0.028 0.006 6.25 0.051 0.001 625 0.53 0.0001 625000 2.4 0.0000006 Conclusions 1 2 16 2 4 1 7 10 17 18 19 21