A health condition survey was made of Japanese persons in the prime of life regarding six abnormalities (obesity, impaired glucose tolerance, hypertension, hypercholesterolemia, hypertriglyceridemia, liver dysfunction) occurring with high frequency. It was demonstrated that impaired liver function and elevation in blood cholesterol are the main causes of health deterioration in persons in the prime of life. The survey results suggest that the deterioration of their health is associated with their lifestyle.