Traits of dairy cattle known to contribute to genetic merit are discussed briefly. Focus is on alternative measures and research to reflect more closely genetic pathways of performance because knowledge is expanding about cellular, organ, and animal function. Improved measurement of physiological traits of economic characters portends increased genetic control of animal productivity by considering more alternative traits. Research should clarify multiple trait selection programs to maximize profit. The null hypothesis to test is that selection for milk is optimal index selection for milk income and costs of production.