African hedgehogs are susceptible to aging changes like those of other small exotic mammals. Common conditions of the geriatric hedgehog include heart disease, chronic renal disease, and dental/periodontal disease. Hedgehogs are unique in that they have an unusually short life span and a propensity for neoplasia. These 2 factors make it especially common for exotic animal practitioners to encounter geriatric hedgehogs affected by one of the many conditions outlined in this article.