Dental caries is one of the most important chronic oral diseases that seriously threaten human health. Because of the characteristics of high incidence, low rate of treatment and high rate of retreatment, conventional prevention and treatment strategies cannot effectively control the occurrence of caries. This article proposes the concept of whole life cycle management of dental caries, focusing on group management of dental caries according to different ages and physiological characteristics on one hand, and personal management of dental caries according to various risk factors and risk levels of individual patient on the other hand, to achieve the goals of controlling the multiple factors that affect the development of dental caries, restoring the oral microecological balance, and further controlling the progress of caries and reconstructing the structure and function of carious teeth.