Walsh, Christopher T
Publication with MATCHING institution:
- Walsh CT (2002) Combinatorial biosynthesis of antibiotics: challenges and opportunities. ChemBioChem. [IF=0.691,
Cited=81, 11921390].
- Walsh CT, Garneau-Tsodikova S, Gatto GJ (2005) Protein posttranslational modifications: the chemistry of proteome
diversifications. Angewandte Chemie - International Edition. [IF=2.456, Cited=619, 16267872].
- Walsh CT, Fischbach MA (2008) Inhibitors of sterol biosynthesis as Staphylococcus aureus antibiotics. Angewandte Chemie
- International Edition. [IF=2.456, Cited=10, 18576462].
- Walsh CT, O'Brien RV, Khosla C (2013) Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid
polyketide scaffolds. Angewandte Chemie - International Edition. [IF=2.456, Cited=129, 23729217].
- Walsh CT, O'Connor SE, Schneider TL (2003) Polyketide-nonribosomal peptide epothilone antitumor agents: the EpoA, B, C
subunits. Journal of Industrial Microbiology and Biotechnology. [IF=1.016, Cited=6, 12707798].
- Walsh CT, Fisher SL, Park IS, ..., Wu Z (1996) Bacterial resistance to vancomycin: five genes and one missing hydrogen
bond tell the story. None. [IF=None, Cited=177, 8807824].
- Walsh CT, Benson TE, Kim DH, Lees WJ (1996) The versatility of phosphoenolpyruvate and its vinyl ether products in
biosynthesis. None. [IF=None, Cited=24, 8807832].
- Walsh CT, Chen H, Keating TA, ..., Patel HM (2001) Tailoring enzymes that modify nonribosomal peptides during and after
chain elongation on NRPS assembly lines. Current Opinion in Chemical Biology. [IF=1.51, Cited=148, 11578925].
- Walsh CT, Gehring AM, Weinreb PH, ..., Flugel RS (1997) Post-translational modification of polyketide and nonribosomal
peptide synthases. Current Opinion in Chemical Biology. [IF=1.51, Cited=141, 9667867].
- Kelleher NL, Zubarev RA, Bush K, ..., Walsh CT (1999) Localization of labile posttranslational modifications by electron
capture dissociation: the case of gamma-carboxyglutamic acid. Analytical Chemistry. [IF=1.41, Cited=183, 10517147].
- Walsh CT (2007) The chemical versatility of natural-product assembly lines. Accounts of Chemical Research. [IF=3.533,
Cited=102, 17506516].
- Krebs C, Galonić Fujimori D, Walsh CT, Bollinger JM (2007) Non-heme Fe(IV)-oxo intermediates. Accounts of Chemical
Research. [IF=3.533, Cited=349, 17542550].
- Zamble DB, McClure CP, Penner-Hahn JE, Walsh CT (2000) The McbB component of microcin B17 synthetase is a zinc
metalloprotein. Biochemistry. [IF=0.753, Cited=14, 11123948].
- Keating TA, Marshall CG, Walsh CT (2000) Vibriobactin biosynthesis in Vibrio cholerae: VibH is an amide synthase
homologous to nonribosomal peptide synthetase condensation domains. Biochemistry. [IF=0.753, Cited=64, 11112537].
- Keating TA, Marshall CG, Walsh CT (2000) Reconstitution and characterization of the Vibrio cholerae vibriobactin
synthetase from VibB, VibE, VibF, and VibH. Biochemistry. [IF=0.753, Cited=65, 11112538].
- Miller DA, Walsh CT (2001) Yersiniabactin synthetase: probing the recognition of carrier protein domains by the
catalytic heterocyclization domains, Cy1 and Cy2, in the chain-initiating HWMP2 subunit. Biochemistry. [IF=0.753,
Cited=18, 11318656].
- Trauger JW, Kohli RM, Walsh CT (2001) Cyclization of backbone-substituted peptides catalyzed by the thioesterase domain
from the tyrocidine nonribosomal peptide synthetase. Biochemistry. [IF=0.753, Cited=55, 11401554].
- Kohli RM, Trauger JW, Schwarzer D, ..., Walsh CT (2001) Generality of peptide cyclization catalyzed by isolated
thioesterase domains of nonribosomal peptide synthetases. Biochemistry. [IF=0.753, Cited=75, 11401555].
- Losey HC, Peczuh MW, Chen Z, ..., Walsh CT (2001) Tandem action of glycosyltransferases in the maturation of vancomycin
and teicoplanin aglycones: novel glycopeptides. Biochemistry. [IF=0.753, Cited=88, 11294642].
- Admiraal SJ, Walsh CT, Walsh CT, ..., Khosla C (2001) The loading module of rifamycin synthetase is an adenylation-
thiolation didomain with substrate tolerance for substituted benzoates. Biochemistry. [IF=0.753, Cited=36, 11352749].
- Patel HM, Walsh CT (2001) In vitro reconstitution of the Pseudomonas aeruginosa nonribosomal peptide synthesis of
pyochelin: characterization of backbone tailoring thiazoline reductase and N-methyltransferase activities. Biochemistry.
[IF=0.753, Cited=49, 11467965].
- Marshall CG, Burkart MD, Keating TA, Walsh CT (2001) Heterocycle formation in vibriobactin biosynthesis: alternative
substrate utilization and identification of a condensed intermediate. Biochemistry. [IF=0.753, Cited=24, 11524010].
- Chen H, Thomas MG, O'Connor SE, ..., Walsh CT (2001) Aminoacyl-S-enzyme intermediates in beta-hydroxylations and
alpha,beta-desaturations of amino acids in peptide antibiotics. Biochemistry. [IF=0.753, Cited=37, 11570865].
- Marshall CG, Hillson NJ, Walsh CT (2002) Catalytic mapping of the vibriobactin biosynthetic enzyme VibF. Biochemistry.
[IF=0.753, Cited=43, 11772022].
- O'Connor SE, Chen H, Walsh CT (2002) Enzymatic assembly of epothilones: the EpoC subunit and reconstitution of the EpoA-
ACP/B/C polyketide and nonribosomal peptide interfaces. Biochemistry. [IF=0.753, Cited=21, 11969430].
- Admiraal SJ, Khosla C, Walsh CT (2002) The loading and initial elongation modules of rifamycin synthetase collaborate to
produce mixed aryl ketide products. Biochemistry. [IF=0.753, Cited=16, 11955082].
- Marshall CG, Burkart MD, Meray RK, Walsh CT (2002) Carrier protein recognition in siderophore-producing nonribosomal
peptide synthetases. Biochemistry. [IF=0.753, Cited=16, 12081492].
- Luo L, Kohli RM, Onishi M, ..., Walsh CT (2002) Timing of epimerization and condensation reactions in nonribosomal
peptide assembly lines: kinetic analysis of phenylalanine activating elongation modules of tyrocidine synthetase B.
Biochemistry. [IF=0.753, Cited=40, 12119033].
- Tseng CC, Bruner SD, Kohli RM, ..., Sieber SA (2002) Characterization of the surfactin synthetase C-terminal
thioesterase domain as a cyclic depsipeptide synthase. Biochemistry. [IF=0.753, Cited=58, 12416979].
- Roche ED, Walsh CT (2003) Dissection of the EntF condensation domain boundary and active site residues in nonribosomal
peptide synthesis. Biochemistry. [IF=0.753, Cited=42, 12564937].
- Hillson NJ, Walsh CT (2003) Dimeric structure of the six-domain VibF subunit of vibriobactin synthetase: mutant domain
activity regain and ultracentrifugation studies. Biochemistry. [IF=0.753, Cited=15, 12534289].
- Freel Meyers CL, Oberthür M, Anderson JW, ..., Walsh CT (2003) Initial characterization of novobiocic acid noviosyl
transferase activity of NovM in biosynthesis of the antibiotic novobiocin. Biochemistry. [IF=0.753, Cited=23, 12680772].
- Schneider TL, Shen B, Walsh CT (2003) Oxidase domains in epothilone and bleomycin biosynthesis: thiazoline to thiazole
oxidation during chain elongation. Biochemistry. [IF=0.753, Cited=50, 12911314].
- Patel HM, Tao J, Walsh CT (2003) Epimerization of an L-cysteinyl to a D-cysteinyl residue during thiazoline ring
formation in siderophore chain elongation by pyochelin synthetase from Pseudomonas aeruginosa. Biochemistry. [IF=0.753,
Cited=35, 12950179].
- Clugston SL, Sieber SA, Marahiel MA, Walsh CT (2003) Chirality of peptide bond-forming condensation domains in
nonribosomal peptide synthetases: the C5 domain of tyrocidine synthetase is a (D)C(L) catalyst. Biochemistry. [IF=0.753,
Cited=49, 14556641].
- Mazur MT, Walsh CT, Kelleher NL (2003) Site-specific observation of acyl intermediate processing in thiotemplate
biosynthesis by fourier transform mass spectrometry: the polyketide module of yersiniabactin synthetase. Biochemistry.
[IF=0.753, Cited=20, 14621984].
- Tseng CC, McLoughlin SM, Kelleher NL, Walsh CT (2004) Role of the active site cysteine of DpgA, a bacterial type III
polyketide synthase. Biochemistry. [IF=0.753, Cited=17, 14744141].
- Lu W, Leimkuhler C, Oberthür M, ..., Walsh CT (2004) AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the
anthracycline aclacinomycin A. Biochemistry. [IF=0.753, Cited=29, 15078101].
- Mulichak AM, Lu W, Losey HC, ..., Garavito RM (2004) Crystal structure of vancosaminyltransferase GtfD from the
vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands. Biochemistry. [IF=0.753, Cited=78, 15122882].
- Pacholec M, Freel Meyers CL, Oberthür M, ..., Walsh CT (2005) Characterization of the aminocoumarin ligase SimL from the
simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway. Biochemistry. [IF=0.753,
Cited=18, 15779922].
- Garneau S, Dorrestein PC, Kelleher NL, Walsh CT (2005) Characterization of the formation of the pyrrole moiety during
clorobiocin and coumermycin A1 biosynthesis. Biochemistry. [IF=0.753, Cited=50, 15723521].
- Schneider TL, Walsh CT (2004) Portability of oxidase domains in nonribosomal peptide synthetase modules. Biochemistry.
[IF=0.753, Cited=12, 15595851].
- Freel Meyers CL, Oberthür M, Heide L, ..., Walsh CT (2004) Assembly of dimeric variants of coumermycins by tandem action
of the four biosynthetic enzymes CouL, CouM, CouP, and NovN. Biochemistry. [IF=0.753, Cited=20, 15554710].
- Hillson NJ, Balibar CJ, Walsh CT (2004) Catalytically inactive condensation domain C1 is responsible for the
dimerization of the VibF subunit of vibriobactin synthetase. Biochemistry. [IF=0.753, Cited=11, 15366944].
- Gatto GJ, McLoughlin SM, Kelleher NL, Walsh CT (2005) Elucidating the substrate specificity and condensation domain
activity of FkbP, the FK520 pipecolate-incorporating enzyme. Biochemistry. [IF=0.753, Cited=34, 15835888].
- Kelly WL, Hillson NJ, Walsh CT (2005) Excision of the epothilone synthetase B cyclization domain and demonstration of in
trans condensation/cyclodehydration activity. Biochemistry. [IF=0.753, Cited=18, 16201763].
- McLoughlin SM, Mazur MT, Miller LM, ..., Kelleher NL (2005) Chemoenzymatic approaches for streamlined detection of
active site modifications on thiotemplate assembly lines using mass spectrometry. Biochemistry. [IF=0.753, Cited=6, 16245932].
- Pacholec M, Hillson NJ, Walsh CT (2005) NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl
enzyme during aminocoumarin ring formation in novobiocin biosynthesis. Biochemistry. [IF=0.753, Cited=12, 16171397].
- Pacholec M, Tao J, Walsh CT (2005) CouO and NovO: C-methyltransferases for tailoring the aminocoumarin scaffold in
coumermycin and novobiocin antibiotic biosynthesis. Biochemistry. [IF=0.753, Cited=27, 16274243].
- Howard-Jones AR, Walsh CT (2005) Enzymatic generation of the chromopyrrolic acid scaffold of rebeccamycin by the tandem
action of RebO and RebD. Biochemistry. [IF=0.753, Cited=52, 16313168].
- Dorrestein PC, Blackhall J, Straight PD, ..., Kelleher NL (2006) Activity screening of carrier domains within
nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry.
[IF=0.753, Cited=37, 16460000].
- Yeh E, Cole LJ, Barr EW, ..., Walsh CT (2006) Flavin redox chemistry precedes substrate chlorination during the reaction
of the flavin-dependent halogenase RebH. Biochemistry. [IF=0.753, Cited=63, 16784243].
- Garneau-Tsodikova S, Stapon A, Kahne D, ..., Walsh CT (2006) Installation of the pyrrolyl-2-carboxyl pharmacophore by
CouN1 and CouN7 in the late biosynthetic steps of the aminocoumarin antibiotics clorobiocin and coumermycin A1.
Biochemistry. [IF=0.753, Cited=17, 16834331].
- Larsen NA, Lin H, Wei R, ..., Walsh CT (2006) Structural characterization of enterobactin hydrolase IroE. Biochemistry.
[IF=0.753, Cited=27, 16922493].
- Dorrestein PC, Bumpus SB, Calderone CT, ..., Kelleher NL (2006) Facile detection of acyl and peptidyl intermediates on
thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry.
Biochemistry. [IF=0.753, Cited=92, 17042494].
- Balibar CJ, Walsh CT (2006) GliP, a multimodular nonribosomal peptide synthetase in Aspergillus fumigatus, makes the
diketopiperazine scaffold of gliotoxin. Biochemistry. [IF=0.753, Cited=89, 17154540].
- Kelly WL, Boyne MT, Yeh E, ..., Walsh CT (2007) Characterization of the aminocarboxycyclopropane-forming enzyme CmaC.
Biochemistry. [IF=0.753, Cited=27, 17209546].
- Lai JR, Koglin A, Walsh CT (2006) Carrier protein structure and recognition in polyketide and nonribosomal peptide
biosynthesis. Biochemistry. [IF=0.753, Cited=55, 17154525].
- Balibar CJ, Walsh CT (2006) In vitro biosynthesis of violacein from L-tryptophan by the enzymes VioA-E from
Chromobacterium violaceum. Biochemistry. [IF=0.753, Cited=91, 17176066].
- Yeh E, Blasiak LC, Koglin A, ..., Walsh CT (2007) Chlorination by a long-lived intermediate in the mechanism of flavin-
dependent halogenases. Biochemistry. [IF=0.753, Cited=113, 17260957].
- Ames BD, Walsh CT (2010) Anthranilate-activating modules from fungal nonribosomal peptide assembly lines. Biochemistry.
[IF=0.753, Cited=51, 20225828].
- Ames BD, Liu X, Walsh CT (2010) Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the
generation of multicyclic scaffolds in fungal indole alkaloid biosynthesis. Biochemistry. [IF=0.753, Cited=53, 20804163].
- Mahlstedt S, Fielding EN, Moore BS, Walsh CT (2010) Prephenate decarboxylases: a new prephenate-utilizing enzyme family
that performs nonaromatizing decarboxylation en route to diverse secondary metabolites. Biochemistry. [IF=0.753,
Cited=19, 20863139].
- Zhang W, Heemstra JR, Walsh CT, Imker HJ (2010) Activation of the pacidamycin PacL adenylation domain by MbtH-like
proteins. Biochemistry. [IF=0.753, Cited=60, 20964365].
- Li B, Walsh CT (2011) Streptomyces clavuligerus HlmI is an intramolecular disulfide-forming dithiol oxidase in holomycin
biosynthesis. Biochemistry. [IF=0.753, Cited=46, 21504228].
- Hollenhorst MA, Ntai I, Badet B, ..., Walsh CT (2011) A head-to-head comparison of eneamide and epoxyamide inhibitors of
glucosamine-6-phosphate synthase from the dapdiamide biosynthetic pathway. Biochemistry. [IF=0.753, Cited=10, 21520904].
- Haynes SW, Ames BD, Gao X, ..., Walsh CT (2011) Unraveling terminal C-domain-mediated condensation in fungal
biosynthesis of imidazoindolone metabolites. Biochemistry. [IF=0.753, Cited=30, 21591693].
- Jiang W, Heemstra JR, Forseth RR, ..., Walsh CT (2011) Biosynthetic chlorination of the piperazate residue in kutzneride
biosynthesis by KthP. Biochemistry. [IF=0.753, Cited=23, 21648411].
- Zhang W, Ames BD, Walsh CT (2011) Identification of phenylalanine 3-hydroxylase for meta-tyrosine biosynthesis.
Biochemistry. [IF=0.753, Cited=22, 21615132].
- Ames BD, Haynes SW, Gao X, ..., Walsh CT (2011) Complexity generation in fungal peptidyl alkaloid biosynthesis:
oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from
Aspergillus fumigatus. Biochemistry. [IF=0.753, Cited=36, 21899262].
- Parker JB, Walsh CT (2012) Olefin isomerization regiochemistries during tandem action of BacA and BacB on prephenate in
bacilysin biosynthesis. Biochemistry. [IF=0.753, Cited=11, 22483065].
- Parker JB, Walsh CT (2012) Stereochemical outcome at four stereogenic centers during conversion of prephenate to
tetrahydrotyrosine by BacABGF in the bacilysin pathway. Biochemistry. [IF=0.753, Cited=6, 22765234].
- Wencewicz TA, Walsh CT (2012) Pseudomonas syringae self-protection from tabtoxinine-β-lactam by ligase TblF and
acetylase Ttr. Biochemistry. [IF=0.753, Cited=8, 22994681].
- Parker JB, Walsh CT (2013) Action and timing of BacC and BacD in the late stages of biosynthesis of the dipeptide
antibiotic bacilysin. Biochemistry. [IF=0.753, Cited=19, 23317005].
- Khosla C, Herschlag D, Cane DE, Walsh CT (2014) Assembly line polyketide synthases: mechanistic insights and unsolved
problems. Biochemistry. [IF=0.753, Cited=62, 24779441].
- Setser JW, Heemstra JR, Walsh CT, Drennan CL (2014) Crystallographic evidence of drastic conformational changes in the
active site of a flavin-dependent N-hydroxylase. Biochemistry. [IF=0.753, Cited=12, 25184411].
- Strieter ER, Vaillancourt FH, Walsh CT (2007) CmaE: a transferase shuttling aminoacyl groups between carrier protein
domains in the coronamic acid biosynthetic pathway. Biochemistry. [IF=0.753, Cited=16, 17530782].
- Fridman M, Balibar CJ, Lupoli T, ..., Garneau-Tsodikova S (2007) Chemoenzymatic formation of novel aminocoumarin
antibiotics by the enzymes CouN1 and CouN7. Biochemistry. [IF=0.753, Cited=20, 17580964].
- Nolan EM, Walsh CT (2008) Investigations of the MceIJ-catalyzed posttranslational modification of the microcin E492
C-terminus: linkage of ribosomal and nonribosomal peptides to form "trojan horse" antibiotics. Biochemistry. [IF=0.753,
Cited=30, 18690711].
- Ryan KS, Chakraborty S, Howard-Jones AR, ..., Drennan CL (2008) The FAD cofactor of RebC shifts to an IN conformation
upon flavin reduction. Biochemistry. [IF=0.753, Cited=19, 19035832].
- Singh GM, Fortin PD, Koglin A, Walsh CT (2008) beta-Hydroxylation of the aspartyl residue in the phytotoxin syringomycin
E: characterization of two candidate hydroxylases AspH and SyrP in Pseudomonas syringae. Biochemistry. [IF=0.753,
Cited=37, 18826255].
- Matthews ML, Krest CM, Barr EW, ..., Bollinger JM (2009) Substrate-triggered formation and remarkable stability of the
C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2. Biochemistry. [IF=0.753, Cited=113, 19245217].
- Liu X, Walsh CT (2009) Cyclopiazonic acid biosynthesis in Aspergillus sp.: characterization of a reductase-like R*
domain in cyclopiazonate synthetase that forms and releases cyclo-acetoacetyl-L-tryptophan. Biochemistry. [IF=0.753,
Cited=72, 19663400].
- Hollenhorst MA, Clardy J, Walsh CT (2009) The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-
dipeptide scaffold of the dapdiamide antibiotics. Biochemistry. [IF=0.753, Cited=28, 19807062].
- Liu X, Walsh CT (2009) Characterization of cyclo-acetoacetyl-L-tryptophan dimethylallyltransferase in cyclopiazonic acid
biosynthesis: substrate promiscuity and site directed mutagenesis studies. Biochemistry. [IF=0.753, Cited=29, 19877600].
- Mahlstedt SA, Walsh CT (2010) Investigation of anticapsin biosynthesis reveals a four-enzyme pathway to
tetrahydrotyrosine in Bacillus subtilis. Biochemistry. [IF=0.753, Cited=25, 20052993].
- Gehring AM, Lees WJ, Mindiola DJ, ..., Brown ED (1996) Acetyltransfer precedes uridylyltransfer in the formation of UDP-
N-acetylglucosamine in separable active sites of the bifunctional GlmU protein of Escherichia coli. Biochemistry.
[IF=0.753, Cited=52, 8555230].
- Lees WJ, Benson TE, Hogle JM, Walsh CT (1996) (E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-
acetylenolpyruvylglucosamine reductase (MurB). Biochemistry. [IF=0.753, Cited=9, 8634262].
- Fisher SL, Kim SK, Wanner BL, Walsh CT (1996) Kinetic comparison of the specificity of the vancomycin resistance VanSfor
two response regulators, VanR and PhoB. Biochemistry. [IF=0.753, Cited=57, 8664263].
- Kim DH, Lees WJ, Kempsell KE, ..., Walsh CT (1996) Characterization of a Cys115 to Asp substitution in the Escherichia
coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by
the antibiotic fosfomycin. Biochemistry. [IF=0.753, Cited=104, 8664284].
- Kim DH, Tucker-Kellogg GW, Lees WJ, Walsh CT (1996) Analysis of fluoromethyl group chirality establishes a common
stereochemical course for the enolpyruvyl transfers catalyzed by EPSP synthase and UDP-GlcNAc enolpyruvyl transferase.
Biochemistry. [IF=0.753, Cited=9, 8611533].
- Park IS, Lin CH, Walsh CT (1996) Gain of D-alanyl-D-lactate or D-lactyl-D-alanine synthetase activities in three active-
site mutants of the Escherichia coli D-alanyl-D-alanine ligase B. Biochemistry. [IF=0.753, Cited=26, 8756703].
- Wang J, Walsh CT (1997) Mechanistic studies on full length and the catalytic domain of the tandem SH2 domain-containing
protein tyrosine phosphatase: analysis of phosphoenzyme levels and Vmax stimulatory effects of glycerol and of a
phosphotyrosyl peptide ligand. Biochemistry. [IF=0.753, Cited=6, 9062130].
- Grace MR, Walsh CT, Cole PA (1997) Divalent ion effects and insights into the catalytic mechanism of protein tyrosine
kinase Csk. Biochemistry. [IF=0.753, Cited=27, 9048573].
- Benson TE, Walsh CT, Massey V (1997) Kinetic characterization of wild-type and S229A mutant MurB: evidence for the role
of Ser 229 as a general acid. Biochemistry. [IF=0.753, Cited=25, 9020777].
- Benson TE, Walsh CT, Hogle JM (1997) X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of
the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Biochemistry. [IF=0.753, Cited=26, 9020778].
- Fan C, Park IS, Walsh CT, Knox JR (1997) D-alanine:D-alanine ligase: phosphonate and phosphinate intermediates with wild
type and the Y216F mutant. Biochemistry. [IF=0.753, Cited=46, 9054558].
- Li S, Furie BC, Furie B, Walsh CT (1997) The propeptide of the vitamin K-dependent carboxylase substrate accelerates
formation of the gamma-glutamyl carbanion intermediate. Biochemistry. [IF=0.753, Cited=1, 9174354].
- Gehring AM, Bradley KA, Walsh CT (1997) Enterobactin biosynthesis in Escherichia coli: isochorismate lyase (EntB) is a
bifunctional enzyme that is phosphopantetheinylated by EntD and then acylated by EntE using ATP and
2,3-dihydroxybenzoate. Biochemistry. [IF=0.753, Cited=125, 9214294].
- McCafferty DG, Lessard IA, Walsh CT (1997) Mutational analysis of potential zinc-binding residues in the active site of
the enterococcal D-Ala-D-Ala dipeptidase VanX. Biochemistry. [IF=0.753, Cited=65, 9265630].
- Carreras CW, Gehring AM, Walsh CT, ..., Khosla C (1997) Utilization of enzymatically phosphopantetheinylated acyl
carrier proteins and acetyl-acyl carrier proteins by the actinorhodin polyketide synthase. Biochemistry. [IF=0.753,
Cited=23, 9305965].
- Lin CH, Kwon DS, Bollinger JM, Walsh CT (1997) Evidence for a glutathionyl-enzyme intermediate in the amidase activity
of the bifunctional glutathionylspermidine synthetase/amidase from Escherichia coli. Biochemistry. [IF=0.753, Cited=21, 9398217].
- Weinreb PH, Quadri LE, Walsh CT, Zuber P (1998) Stoichiometry and specificity of in vitro phosphopantetheinylation and
aminoacylation of the valine-activating module of surfactin synthetase. Biochemistry. [IF=0.753, Cited=26, 9484228].
- Quadri LE, Weinreb PH, Lei M, ..., Walsh CT (1998) Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl
transferase for peptidyl carrier protein domains in peptide synthetases. Biochemistry. [IF=0.753, Cited=370, 9484229].
- Skarzynski T, Kim DH, Lees WJ, ..., Duncan K (1998) Stereochemical course of enzymatic enolpyruvyl transfer and
catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction
tetrahedral intermediate bound to the active site of the C115A mutant of MurA. Biochemistry. [IF=0.753, Cited=30, 9485407].
- Gehring AM, Mori I, Walsh CT (1998) Reconstitution and characterization of the Escherichia coli enterobactin synthetase
from EntB, EntE, and EntF. Biochemistry. [IF=0.753, Cited=132, 9485415].
- Sinha Roy R, Belshaw PJ, Walsh CT (1998) Mutational analysis of posttranslational heterocycle biosynthesis in the gyrase
inhibitor microcin B17: distance dependence from propeptide and tolerance for substitution in a GSCG cyclizable
sequence. Biochemistry. [IF=0.753, Cited=29, 9521734].
- Milne JC, Eliot AC, Kelleher NL, Walsh CT (1998) ATP/GTP hydrolysis is required for oxazole and thiazole biosynthesis in
the peptide antibiotic microcin B17. Biochemistry. [IF=0.753, Cited=33, 9748332].
- Gehring AM, Mori I, Perry RD, Walsh CT (1998) The nonribosomal peptide synthetase HMWP2 forms a thiazoline ring during
biogenesis of yersiniabactin, an iron-chelating virulence factor of Yersinia pestis. Biochemistry. [IF=0.753, Cited=78, 9709002].
- Milne JC, Roy RS, Eliot AC, ..., Walsh CT (1999) Cofactor requirements and reconstitution of microcin B17 synthetase: a
multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17. Biochemistry.
[IF=0.753, Cited=55, 10200165].
- Ehmann DE, Gehring AM, Walsh CT (1999) Lysine biosynthesis in Saccharomyces cerevisiae: mechanism of alpha-aminoadipate
reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5. Biochemistry. [IF=0.753, Cited=103, 10320345].
- Kelleher NL, Hendrickson CL, Walsh CT (1999) Posttranslational heterocyclization of cysteine and serine residues in the
antibiotic microcin B17: distributivity and directionality. Biochemistry. [IF=0.753, Cited=41, 10569947].
- Lessard IA, Healy VL, Park IS, Walsh CT (1999) Determinants for differential effects on D-Ala-D-lactate vs D-Ala-D-Ala
formation by the VanA ligase from vancomycin-resistant enterococci. Biochemistry. [IF=0.753, Cited=23, 10529248].
- Suo Z, Walsh CT, Miller DA (1999) Tandem heterocyclization activity of the multidomain 230 kDa HMWP2 subunit of Yersinia
pestis yersiniabactin synthetase: interaction of the 1-1382 and 1383-2035 fragments. Biochemistry. [IF=0.753, Cited=25, 10529249].
- Quadri LE, Keating TA, Patel HM, Walsh CT (1999) Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore
pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.
Biochemistry. [IF=0.753, Cited=70, 10555976].
- Keating TA, Suo Z, Ehmann DE, Walsh CT (2000) Selectivity of the yersiniabactin synthetase adenylation domain in the
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andrimid biosynthetic assembly line. ACS Chemical Biology. [IF=0.963, Cited=20, 18652473].
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gramicidin S synthetase. Journal of the American Chemical Society. [IF=2.573, Cited=29, 11697963].
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the American Chemical Society. [IF=2.573, Cited=33, 12149006].
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epothilone synthetase assembly line. Journal of the American Chemical Society. [IF=2.573, Cited=13, 12236733].
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the isolated thioesterase domain of epothilone polyketide synthase. Journal of the American Chemical Society. [IF=2.573,
Cited=31, 12643694].
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characterizing macrocyclization by thioesterase domains. Journal of the American Chemical Society. [IF=2.573, Cited=35, 12952465].
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polyketide modules of the rifamycin synthetase assembly line. Journal of the American Chemical Society. [IF=2.573,
Cited=10, 14599196].
- Yin J, Liu F, Schinke M, ..., Walsh CT (2004) Phagemid encoded small molecules for high throughput screening of chemical
libraries. Journal of the American Chemical Society. [IF=2.573, Cited=28, 15493886].
- Lin H, Walsh CT (2004) A chemoenzymatic approach to glycopeptide antibiotics. Journal of the American Chemical Society.
[IF=2.573, Cited=55, 15506762].
- Yin J, Liu F, Li X, Walsh CT (2004) Labeling proteins with small molecules by site-specific posttranslational
modification. Journal of the American Chemical Society. [IF=2.573, Cited=108, 15212504].
- Lee HY, Chung HS, Hang C, ..., Walker S (2004) Reconstitution and characterization of a new desosaminyl transferase,
EryCIII, from the erythromycin biosynthetic pathway. Journal of the American Chemical Society. [IF=2.573, Cited=12, 15303858].
- Lin H, Fischbach MA, Liu DR, Walsh CT (2005) In vitro characterization of salmochelin and enterobactin trilactone
hydrolases IroD, IroE, and Fes. Journal of the American Chemical Society. [IF=2.573, Cited=108, 16076215].
- Oberthür M, Leimkuhler C, Kruger RG, ..., Kahne D (2005) A systematic investigation of the synthetic utility of
glycopeptide glycosyltransferases. Journal of the American Chemical Society. [IF=2.573, Cited=41, 16045364].
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unnatural macrolides. Journal of the American Chemical Society. [IF=2.573, Cited=34, 16218575].
- Aron ZD, Dorrestein PC, Blackhall JR, ..., Walsh CT (2005) Characterization of a new tailoring domain in polyketide
biogenesis: the amine transferase domain of MycA in the mycosubtilin gene cluster. Journal of the American Chemical
Society. [IF=2.573, Cited=34, 16248612].
- Frueh DP, Sun ZYJ, Vosburg DA, ..., Wagner G (2006) Non-uniformly sampled double-TROSY hNcaNH experiments for NMR
sequential assignments of large proteins. Journal of the American Chemical Society. [IF=2.573, Cited=44, 16637644].
- Gatto GJ, Boyne MT, Kelleher NL, Walsh CT (2006) Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded
in the rapamycin gene cluster. Journal of the American Chemical Society. [IF=2.573, Cited=68, 16536560].
- Galonić DP, Vaillancourt FH, Walsh CT (2006) Halogenation of unactivated carbon centers in natural product biosynthesis:
trichlorination of leucine during barbamide biosynthesis. Journal of the American Chemical Society. [IF=2.573,
Cited=77, 16551084].
- Lin H, Fischbach MA, Gatto GJ, ..., Walsh CT (2006) Bromoenterobactins as potent inhibitors of a pathogen-associated,
siderophore-modifying C-glycosyltransferase. Journal of the American Chemical Society. [IF=2.573, Cited=5, 16848455].
- Lai JR, Fischbach MA, Liu DR, Walsh CT (2006) Localized protein interaction surfaces on the EntB carrier protein
revealed by combinatorial mutagenesis and selection. Journal of the American Chemical Society. [IF=2.573, Cited=30, 16925399].
- Garneau-Tsodikova S, Dorrestein PC, Kelleher NL, Walsh CT (2006) Protein assembly line components in prodigiosin
biosynthesis: characterization of PigA,G,H,I,J. Journal of the American Chemical Society. [IF=2.573, Cited=36, 17002325].
- Howard-Jones AR, Walsh CT (2006) Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP,
StaC, and RebC on chromopyrrolic acid. Journal of the American Chemical Society. [IF=2.573, Cited=62, 16967980].
- Magarvey NA, Ehling-Schulz M, Walsh CT (2006) Characterization of the cereulide NRPS alpha-hydroxy acid specifying
modules: activation of alpha-keto acids and chiral reduction on the assembly line. Journal of the American Chemical
Society. [IF=2.573, Cited=84, 16910662].
- Hansen DB, Bumpus SB, Aron ZD, ..., Walsh CT (2007) The loading module of mycosubtilin: an adenylation domain with fatty
acid selectivity. Journal of the American Chemical Society. [IF=2.573, Cited=39, 17472382].
- Leimkuhler C, Fridman M, Lupoli T, ..., Kahne D (2007) Characterization of rhodosaminyl transfer by the AknS/AknT
glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A. Journal of the American
Chemical Society. [IF=2.573, Cited=16, 17685523].
- Howard-Jones AR, Kruger RG, Lu W, ..., Walsh CT (2007) Kinetic analysis of teicoplanin glycosyltransferases and
acyltransferase reveal ordered tailoring of aglycone scaffold to reconstitute mature teicoplanin. Journal of the
American Chemical Society. [IF=2.573, Cited=17, 17661468].
- Howard-Jones AR, Walsh CT (2007) Nonenzymatic oxidative steps accompanying action of the cytochrome P450 enzymes StaP
and RebP in the biosynthesis of staurosporine and rebeccamycin. Journal of the American Chemical Society. [IF=2.573,
Cited=31, 17705392].
- Nolan EM, Fischbach MA, Koglin A, Walsh CT (2007) Biosynthetic tailoring of microcin E492m: post-translational
modification affords an antibacterial siderophore-peptide conjugate. Journal of the American Chemical Society.
[IF=2.573, Cited=40, 17973380].
- Fujimori DG, Barr EW, Matthews ML, ..., Riggs-Gelasco PJ (2007) Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo
intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces. Journal of the American Chemical
Society. [IF=2.573, Cited=68, 17939667].
- Read JA, Walsh CT (2007) The lyngbyatoxin biosynthetic assembly line: chain release by four-electron reduction of a
dipeptidyl thioester to the corresponding alcohol. Journal of the American Chemical Society. [IF=2.573, Cited=46, 18044902].
- Zhang W, Bolla ML, Kahne D, ..., Walsh CT (2010) A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation
and incorporation in natural product biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=32, 20394362].
- Bowers AA, Acker MG, Koglin A, Walsh CT (2010) Manipulation of thiocillin variants by prepeptide gene replacement:
structure, conformation, and activity of heterocycle substitution mutants. Journal of the American Chemical Society.
[IF=2.573, Cited=59, 20455532].
- Bowers AA, Walsh CT, Acker MG (2010) Genetic interception and structural characterization of thiopeptide cyclization
precursors from Bacillus cereus. Journal of the American Chemical Society. [IF=2.573, Cited=42, 20707374].
- Hollenhorst MA, Bumpus SB, Matthews ML, ..., Walsh CT (2010) The nonribosomal peptide synthetase enzyme DdaD tethers
N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide
antibiotic biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=19, 20945916].
- Gao X, Chooi YH, Ames BD, ..., Tang Y (2011) Fungal indole alkaloid biosynthesis: genetic and biochemical investigation
of the tryptoquialanine pathway in Penicillium aethiopicum. Journal of the American Chemical Society. [IF=2.573,
Cited=67, 21299212].
- Zhang W, Ntai I, Bolla ML, ..., Walsh CT (2011) Nine enzymes are required for assembly of the pacidamycin group of
peptidyl nucleoside antibiotics. Journal of the American Chemical Society. [IF=2.573, Cited=38, 21417270].
- Bowers AA, Acker MG, Young TS, Walsh CT (2012) Generation of thiocillin ring size variants by prepeptide gene
replacement and in vivo processing by Bacillus cereus. Journal of the American Chemical Society. [IF=2.573, Cited=28, 22686940].
- Cacho RA, Jiang W, Chooi YH, ..., Tang Y (2012) Identification and characterization of the echinocandin B biosynthetic
gene cluster from Emericella rugulosa NRRL 11440. Journal of the American Chemical Society. [IF=2.573, Cited=68, 22998630].
- Haynes SW, Gao X, Tang Y, Walsh CT (2012) Assembly of asperlicin peptidyl alkaloids from anthranilate and tryptophan: a
two-enzyme pathway generates heptacyclic scaffold complexity in asperlicin E. Journal of the American Chemical Society.
[IF=2.573, Cited=26, 23030663].
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blocks of the echinocandin scaffold. Journal of the American Chemical Society. [IF=2.573, Cited=39, 23451921].
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consuming N-P bond formation in microcin C7. Journal of the American Chemical Society. [IF=2.573, Cited=49, 18290647].
- Zhou Z, Koglin A, Wang Y, ..., Walsh CT (2008) An eight residue fragment of an acyl carrier protein suffices for post-
translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo. Journal of the
American Chemical Society. [IF=2.573, Cited=29, 18593165].
- Bumpus SB, Magarvey NA, Kelleher NL, ..., Calderone CT (2008) Polyunsaturated fatty-acid-like trans-enoyl reductases
utilized in polyketide biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=30, 18693732].
- Sattely ES, Walsh CT (2008) A latent oxazoline electrophile for N-O-C bond formation in pseudomonine biosynthesis.
Journal of the American Chemical Society. [IF=2.573, Cited=31, 18710233].
- Neumann CS, Walsh CT (2008) Biosynthesis of (-)-(1S,2R)-allocoronamic acyl thioester by an Fe(II)-dependent halogenase
and a cyclopropane-forming flavoprotein. Journal of the American Chemical Society. [IF=2.573, Cited=33, 18828590].
- Heemstra JR, Walsh CT (2008) Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce
6,7-dichlorotryptophan for kutzneride assembly. Journal of the American Chemical Society. [IF=2.573, Cited=41, 18828589].
- Balskus EP, Walsh CT (2008) Investigating the initial steps in the biosynthesis of cyanobacterial sunscreen scytonemin.
Journal of the American Chemical Society. [IF=2.573, Cited=60, 18954141].
- Strieter ER, Koglin A, Aron ZD, Walsh CT (2009) Cascade reactions during coronafacic acid biosynthesis: elongation,
cyclization, and functionalization during Cfa7-catalyzed condensation. Journal of the American Chemical Society.
[IF=2.573, Cited=10, 19199623].
- Wong C, Fujimori DG, Walsh CT, Drennan CL (2009) Structural analysis of an open active site conformation of nonheme iron
halogenase CytC3. Journal of the American Chemical Society. [IF=2.573, Cited=43, 19281171].
- Wuest WM, Sattely ES, Walsh CT (2009) Three siderophores from one bacterial enzymatic assembly line. Journal of the
American Chemical Society. [IF=2.573, Cited=34, 19320483].
- Frueh DP, Arthanari H, Koglin A, ..., Wagner G (2009) A double TROSY hNCAnH experiment for efficient assignment of large
and challenging proteins. Journal of the American Chemical Society. [IF=2.573, Cited=12, 19702261].
- Strieker M, Nolan EM, Walsh CT, Marahiel MA (2009) Stereospecific synthesis of threo- and erythro-beta-hydroxyglutamic
acid during kutzneride biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=28, 19722489].
- Heemstra JR, Walsh CT, Sattely ES (2009) Enzymatic tailoring of ornithine in the biosynthesis of the Rhizobium cyclic
trihydroxamate siderophore vicibactin. Journal of the American Chemical Society. [IF=2.573, Cited=39, 19778043].
- Balskus EP, Walsh CT (2009) An enzymatic cyclopentyl[b]indole formation involved in scytonemin biosynthesis. Journal of
the American Chemical Society. [IF=2.573, Cited=35, 19780555].
- Acker MG, Bowers AA, Walsh CT (2009) Generation of thiocillin variants by prepeptide gene replacement and in vivo
processing by Bacillus cereus. Journal of the American Chemical Society. [IF=2.573, Cited=44, 19911780].
- Walsh CT, Fischbach MA (2010) Natural products version 2.0: connecting genes to molecules. Journal of the American
Chemical Society. [IF=2.573, Cited=234, 20121095].
- Imker HJ, Walsh CT, Wuest WM (2009) SylC catalyzes ureido-bond formation during biosynthesis of the proteasome inhibitor
syringolin A. Journal of the American Chemical Society. [IF=2.573, Cited=26, 19968303].
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phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from
Escherichia coli. Journal of Medicinal Chemistry. [IF=1.655, Cited=12, 9371250].
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coumarin antibiotic biosynthetic pathway. Organic Letters. [IF=1.091, Cited=5, 12943395].
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biosynthesis. Organic Letters. [IF=1.091, Cited=8, 21812451].
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Letters. [IF=1.091, Cited=37, 21888371].
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synthesis of vancomycin and N- and C-terminus substituent effects of the aglycon substrate. Organic Letters. [IF=1.091,
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machinery. Natural Product Reports. [IF=3.292, Cited=121, 16874387].
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GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=26, 15070728].
- Pi N, Meyers CLF, Pacholec M, ..., Leary JA (2004) Mass spectrometric characterization of a three-enzyme tandem reaction
for assembly and modification of the novobiocin skeleton. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=15, 15218104].
- Ehmann DE, Shaw-Reid CA, Losey HC, Walsh CT (2000) The EntF and EntE adenylation domains of Escherichia coli
enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=67, 10688898].
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C-glycosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
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- Yeh E, Garneau S, Walsh CT (2005) Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase,
generating 7-chlorotryptophan during rebeccamycin biosynthesis. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=135, 15743914].
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O2-dependent halogenase. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
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- Dorrestein PC, Yeh E, Garneau-Tsodikova S, ..., Walsh CT (2005) Dichlorination of a pyrrolyl-S-carrier protein by
FADH2-dependent halogenase PltA during pyoluteorin biosynthesis. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=102, 16162666].
- Yin J, Straight PD, McLoughlin SM, ..., Walsh CT (2005) Genetically encoded short peptide tag for versatile protein
labeling by Sfp phosphopantetheinyl transferase. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=211, 16236721].
- Lai JR, Fischbach MA, Liu DR, Walsh CT (2006) A protein interaction surface in nonribosomal peptide synthesis mapped by
combinatorial mutagenesis and selection. Proceedings of the National Academy of Sciences of the United States of
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- Calderone CT, Kowtoniuk WE, Kelleher NL, ..., Dorrestein PC (2006) Convergence of isoprene and polyketide biosynthetic
machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=98, 16757561].
- Fischbach MA, Lin H, Zhou L, ..., Smith KD (2006) The pathogen-associated iroA gene cluster mediates bacterial evasion
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Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=114, 17190806].
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assembly-line enzymes. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
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enzyme RebC. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=44, 17873060].
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for kutznerides. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=75, 17940045].
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innovation. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=157, 18216259].
- Walsh CT, Nolan EM (2008) Morphing peptide backbones into heterocycles. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=17, 18398003].
- Calderone CT, Bumpus SB, Kelleher NL, ..., Magarvey NA (2008) A ketoreductase domain in the PksJ protein of the
bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=22, 18723688].
- Liu X, Fortin PD, Walsh CT (2008) Andrimid producers encode an acetyl-CoA carboxyltransferase subunit resistant to the
action of the antibiotic. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=34, 18768797].
- Wang Y, Zhou Z, Walsh CT, McMahon AP (2009) Selective translocation of intracellular Smoothened to the primary cilium in
response to Hedgehog pathway modulation. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=127, 19196978].
- Walsh CT, Fischbach MA (2009) Repurposing libraries of eukaryotic protein kinase inhibitors for antibiotic discovery.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=17, 19193851].
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14-residue peptide into the antibiotic thiocillin. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=118, 19196969].
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halogenation and hydroxylation in the aliphatic halogenase, SyrB2. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=111, 19815524].
- Neumann CS, Walsh CT, Kay RR (2010) A flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of
Dictyostelium differentiation-inducing factor 1. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=34, 20231486].
- Li B, Walsh CT (2010) Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces
clavuligerus. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=51, 21041678].
- Pootoolal J, Thomas MG, Marshall CG, ..., Wright GD (2002) Assembling the glycopeptide antibiotic scaffold: The
biosynthesis of A47934 from Streptomyces toyocaensis NRRL15009. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=115, 12060705].
- Zhang W, Ntai I, Kelleher NL, Walsh CT (2011) tRNA-dependent peptide bond formation by the transferase PacB in
biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=39, 21746899].
- Young TS, Walsh CT (2011) Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and
heterologous expression in Streptomyces lividans. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=42, 21788474].
- Mulichak AM, Losey HC, Lu W, ..., Garavito RM (2003) Structure of the TDP-epi-vancosaminyltransferase GtfA from the
chloroeremomycin biosynthetic pathway. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=87, 12874381].
- Malcolmson SJ, Young TS, Ruby JG, ..., Walsh CT (2013) The posttranslational modification cascade to the thiopeptide
berninamycin generates linear forms and altered macrocyclic scaffolds. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=39, 23650400].
- Zamble DB, Miller DA, Heddle JG, ..., Hollfelder F (2001) In vitro characterization of DNA gyrase inhibition by microcin
B17 analogs with altered bisheterocyclic sites. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=26, 11427730].
- Chiu HT, Hubbard BK, Shah AN, ..., Khosla C (2001) Molecular cloning and sequence analysis of the complestatin
biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=91, 11447274].
- Dowling DP, Kung Y, Croft AK, ..., Drennan CL (2016) Structural elements of an NRPS cyclization domain and its
intermodule docking domain. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=37, 27791103].
- Watanabe K, Rude MA, Walsh CT, Khosla C (2003) Engineered biosynthesis of an ansamycin polyketide precursor in
Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=45, 12888623].
- Chen H, Thomas MG, Hubbard BK, ..., Burkart MD (2000) Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of
TDP-L-epivancosamine in chloroeremomycin biosynthesis. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=51, 11035791].
- Chen H, Tseng CC, Hubbard BK, Walsh CT (2001) Glycopeptide antibiotic biosynthesis: enzymatic assembly of the dedicated
amino acid monomer (S)-3,5-dihydroxyphenylglycine. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=52, 11752437].
- Kohli RM, Takagi J, Walsh CT (2002) The thioesterase domain from a nonribosomal peptide synthetase as a cyclization
catalyst for integrin binding peptides. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=28, 11805307].
- Suo Z, Chen H, Walsh CT (2000) Acyl-CoA hydrolysis by the high molecular weight protein 1 subunit of yersiniabactin
synthetase: mutational evidence for a cascade of four acyl-enzyme intermediates during hydrolytic editing. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=16, 11106385].
- Liu J, Walsh CT (1990) Peptidyl-prolyl cis-trans-isomerase from Escherichia coli: a periplasmic homolog of cyclophilin
that is not inhibited by cyclosporin A. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=120, 2190212].
- Ye QZ, Liu J, Walsh CT (1990) p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB
as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=46, 2251281].
- Liu J, Albers MW, Chen CM, ..., Walsh CT (1990) Cloning, expression, and purification of human cyclophilin in
Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=114, 2179953].
- Ramer SE, Winkler DG, Carrera A, ..., Walsh CT (1991) Purification and initial characterization of the lymphoid-cell
protein-tyrosine kinase p56lck from a baculovirus expression system. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=17, 2068105].
- Li PM, Reichert J, Freyd G, ..., Walsh CT (1991) The LIM region of a presumptive Caenorhabditis elegans transcription
factor is an iron-sulfur- and zinc-containing metallodomain. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=31, 1924383].
- Price ER, Zydowsky LD, Jin MJ, ..., Walsh CT (1991) Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-
prolyl isomerase with a signal sequence. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=182, 2000394].
- Kaye RE, Fruman DA, Bierer BE, ..., Walsh CT (1992) Effects of cyclosporin A and FK506 on Fc epsilon receptor type
I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is
associated with a deficiency in FK506-binding protein FKBP12. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=38, 1382293].
- Payne G, Shoelson SE, Gish GD, ..., Walsh CT (1993) Kinetics of p56lck and p60src Src homology 2 domain binding to
tyrosine-phosphorylated peptides determined by a competition assay or surface plasmon resonance. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=58, 7685110].
- Pei D, Neel BG, Walsh CT (1993) Overexpression, purification, and characterization of SHPTP1, a Src homology
2-containing protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=31, 8430079].
- Shi Y, Brown ED, Walsh CT (1994) Expression of recombinant human casein kinase II and recombinant heat shock protein 90
in Escherichia coli and characterization of their interactions. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=36, 8146188].
- Price ER, Jin M, Lim D, ..., McKeon FD (1994) Cyclophilin B trafficking through the secretory pathway is altered by
binding of cyclosporin A. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=72, 7909608].
- Joung I, Kim T, Stolz LA, ..., Shin J (1995) Modification of Ser59 in the unique N-terminal region of tyrosine kinase
p56lck regulates specificity of its Src homology 2 domain. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=36, 7597029].
- Wu Z, Walsh CT (1995) Phosphinate analogs of D-, D-dipeptides: slow-binding inhibition and proteolysis protection of
VanX, a D-, D-dipeptidase required for vancomycin resistance in Enterococcus faecium. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=21, 8524812].
- Haldimann A, Prahalad MK, Fisher SL, ..., Wanner BL (1996) Altered recognition mutants of the response regulator PhoB: a
new genetic strategy for studying protein-protein interactions. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=44, 8962056].
- Pei D, Wang J, Walsh CT (1996) Differential functions of the two Src homology 2 domains in protein tyrosine phosphatase
SH-PTP1. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=69, 8577729].
- Sugiura I, Furie B, Walsh CT, Furie BC (1997) Propeptide and glutamate-containing substrates bound to the vitamin
K-dependent carboxylase convert its vitamin K epoxidase function from an inactive to an active state. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=14, 9256436].
- Park IS, Lin CH, Walsh CT (1997) Bacterial resistance to vancomycin: overproduction, purification, and characterization
of VanC2 from Enterococcus casseliflavus as a D-Ala-D-Ser ligase. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=25, 9294159].
- Silva JC, Haldimann A, Prahalad MK, ..., Wanner BL (1998) In vivo characterization of the type A and B vancomycin-
resistant enterococci (VRE) VanRS two-component systems in Escherichia coli: a nonpathogenic model for studying the VRE
signal transduction pathways. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=42, 9751771].
- Trauger JW, Walsh CT (2000) Heterologous expression in Escherichia coli of the first module of the nonribosomal peptide
synthetase for chloroeremomycin, a vancomycin-type glycopeptide antibiotic. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=16, 10716695].
- Suo Z, Tseng CC, Walsh CT (2001) Purification, priming, and catalytic acylation of carrier protein domains in the
polyketide synthase and nonribosomal peptidyl synthetase modules of the HMWP1 subunit of yersiniabactin synthetase.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=24, 11134531].
- Walsh CT, Acker MG, Bowers AA (2010) Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational
modifications on ribosomal nascent proteins. Journal of Biological Chemistry. [IF=1.122, Cited=53, 20522549].
- Walsh CT (2010) Catalysis at the intersection of biology, chemistry, and medicine. Journal of Biological Chemistry.
[IF=1.122, Cited=1, 20595393].
- Walsh CT, Distefano MD, Moore MJ, ..., Verdine GL (1988) Molecular basis of bacterial resistance to organomercurial and
inorganic mercuric salts. FASEB Journal. [IF=1.029, Cited=39, 3277886].
- Lim FY, Ames B, Walsh CT, Keller NP (2014) Co-ordination between BrlA regulation and secretion of the oxidoreductase
FmqD directs selective accumulation of fumiquinazoline C to conidial tissues in Aspergillus fumigatus. Cellular
Microbiology. [IF=0.89, Cited=45, 24612080].
- Walsh CT (2004) Polyketide and nonribosomal peptide antibiotics: modularity and versatility. Science. [IF=7.729,
Cited=313, 15031493].
- Fischbach MA, Walsh CT (2006) Biochemistry. Directing biosynthesis. Science. [IF=7.729, Cited=14, 17068249].
- Fischbach MA, Walsh CT (2009) Antibiotics for emerging pathogens. Science. [IF=7.729, Cited=813, 19713519].
- Balskus EP, Walsh CT (2010) The genetic and molecular basis for sunscreen biosynthesis in cyanobacteria. Science.
[IF=7.729, Cited=147, 20813918].
- Helmann JD, Ballard BT, Walsh CT (1990) The MerR metalloregulatory protein binds mercuric ion as a tricoordinate, metal-
bridged dimer. Science. [IF=7.729, Cited=64, 2305262].
- Li YM, Milne JC, Madison LL, ..., Walsh CT (1996) From peptide precursors to oxazole and thiazole-containing peptide
antibiotics: microcin B17 synthase. Science. [IF=7.729, Cited=149, 8895467].
- Cane DE, Walsh CT, Walsh CT, ..., Khosla C (1998) Harnessing the biosynthetic code: combinations, permutations, and
mutations. Science. [IF=7.729, Cited=320, 9756477].
- Belshaw PJ, Walsh CT, Stachelhaus T (1999) Aminoacyl-CoAs as probes of condensation domain selectivity in nonribosomal
peptide synthesis. Science. [IF=7.729, Cited=158, 10205056].
- Fan C, Moews PC, Walsh CT, Knox JR (1994) Vancomycin resistance: structure of D-alanine:D-alanine ligase at 2.3 A
resolution. Science. [IF=7.729, Cited=131, 7939684].
- Walsh CT (1993) Vancomycin resistance: decoding the molecular logic. Science. [IF=7.729, Cited=89, 8392747].
- Wright GD, Molinas C, Arthur M, ..., Walsh CT (1992) Characterization of vanY, a DD-carboxypeptidase from vancomycin-
resistant Enterococcus faecium BM4147. Antimicrobial Agents and Chemotherapy. [IF=1.175, Cited=53, 1510448].
- Pfeifer BA, Wang CCC, Walsh CT, Khosla C (2003) Biosynthesis of Yersiniabactin, a complex polyketide-nonribosomal
peptide, using Escherichia coli as a heterologous host. Applied and Environmental Microbiology. [IF=1.103, Cited=58, 14602630].
- Reimmann C, Patel HM, Serino L, ..., Haas D (2001) Essential PchG-dependent reduction in pyochelin biosynthesis of
Pseudomonas aeruginosa. Journal of Bacteriology. [IF=0.898, Cited=66, 11208777].
- Couch R, O'Connor SE, Seidle H, ..., Parry R (2004) Characterization of CmaA, an adenylation-thiolation didomain enzyme
involved in the biosynthesis of coronatine. Journal of Bacteriology. [IF=0.898, Cited=23, 14679222].
- Reimmann C, Patel HM, Walsh CT, Haas D (2004) PchC thioesterase optimizes nonribosomal biosynthesis of the peptide
siderophore pyochelin in Pseudomonas aeruginosa. Journal of Bacteriology. [IF=0.898, Cited=23, 15375116].
- Crosa JH, Walsh CT (2002) Genetics and assembly line enzymology of siderophore biosynthesis in bacteria. Microbiology
and Molecular Biology Reviews. [IF=2.842, Cited=418, 12040125].
- Helmann JD, Wang Y, Mahler I, Walsh CT (1989) Homologous metalloregulatory proteins from both gram-positive and gram-
negative bacteria control transcription of mercury resistance operons. Journal of Bacteriology. [IF=0.898, Cited=35, 2492496].
- Liu J, Duncan K, Walsh CT (1989) Nucleotide sequence of a cluster of Escherichia coli enterobactin biosynthesis genes:
identification of entA and purification of its product 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase. Journal of
Bacteriology. [IF=0.898, Cited=67, 2521622].
- Mayerl F, Piret J, Kiener A, ..., Yasui A (1990) Functional expression of 8-hydroxy-5-deazaflavin-dependent DNA
photolyase from Anacystis nidulans in Streptomyces coelicolor. Journal of Bacteriology. [IF=0.898, Cited=7, 2120199].
- Raybuck SA, Ramer SE, Abbanat DR, ..., Walsh CT (1991) Demonstration of carbon-carbon bond cleavage of acetyl coenzyme A
by using isotopic exchange catalyzed by the CO dehydrogenase complex from acetate-grown Methanosarcina thermophila.
Journal of Bacteriology. [IF=0.898, Cited=19, 1987173].
- Marquardt JL, Siegele DA, Kolter R, Walsh CT (1992) Cloning and sequencing of Escherichia coli murZ and purification of
its product, a UDP-N-acetylglucosamine enolpyruvyl transferase. Journal of Bacteriology. [IF=0.898, Cited=74, 1512209].
- Brown ED, Vivas EI, Walsh CT, Kolter R (1995) MurA (MurZ), the enzyme that catalyzes the first committed step in
peptidoglycan biosynthesis, is essential in Escherichia coli. Journal of Bacteriology. [IF=0.898, Cited=122, 7608103].
- Lorenz U, Ravichandran KS, Pei D, ..., Neel BG (1994) Lck-dependent tyrosyl phosphorylation of the phosphotyrosine
phosphatase SH-PTP1 in murine T cells. Molecular and Cellular Biology. [IF=1.026, Cited=89, 8114715].
- Ma H, Bloom LM, Zhu ZM, ..., Botstein D (1989) Isolation and characterization of mutations in the HXK2 gene of
Saccharomyces cerevisiae. Molecular and Cellular Biology. [IF=1.026, Cited=20, 2685571].
- Ma H, Bloom LM, Walsh CT, Botstein D (1989) The residual enzymatic phosphorylation activity of hexokinase II mutants is
correlated with glucose repression in Saccharomyces cerevisiae. Molecular and Cellular Biology. [IF=1.026, Cited=77, 2685572].
- Tsodikov OV, Hou C, Walsh CT, Garneau-Tsodikova S (2015) Crystal structure of O-methyltransferase CalO6 from the
calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution. BMC Structural
Biology. [IF=1.038, Cited=4, 26170207].
- Rojas Murcia N, Lee X, Waridel P, ..., Reimmann C (2015) The Pseudomonas aeruginosa antimetabolite L -2-amino-4-methoxy-
trans-3-butenoic acid (AMB) is made from glutamate and two alanine residues via a thiotemplate-linked tripeptide
precursor. Frontiers in Microbiology. [IF=1.331, Cited=24, 25814981].
Publication with MISMATCHING institution:
- Walsh CT, Moore BS (2019) Enzymatic Cascade Reactions in Biosynthesis. Angewandte Chemie - International Edition.
[IF=2.456, Cited=33, 30156048].
- Walsh CT (2018) Propofol: Milk of Amnesia. Cell. [IF=8.479, Cited=32, 30217361].
- Walsh CT (2022) Covalent Catalytic Strategies for Enzymes That Modify RNA Molecules on their Tripartite Building Blocks.
ACS Chemical Biology. [IF=0.963, Cited=2, 36103129].
- Walsh CT (2018) Nature Builds Macrocycles and Heterocycles into Its Antimicrobial Frameworks: Deciphering Biosynthetic
Strategy. ACS Infectious Diseases. [IF=0.991, Cited=9, 29993235].
- Tang MC, Zou Y, Watanabe K, ..., Tang Y (2016) Oxidative Cyclization in Natural Product Biosynthesis. Chemical Reviews.
[IF=11.712, Cited=116, 27936626].
- Walsh CT, Tu BP, Tang Y (2017) Eight Kinetically Stable but Thermodynamically Activated Molecules that Power Cell
Metabolism. Chemical Reviews. [IF=11.712, Cited=75, 29272116].
- Walsh CT, Tu BP, Tang Y (2018) Correction to: Eight Kinetically Stable but Thermodynamically Activated Molecules that
Power Cell Metabolism. Chemical Reviews. [IF=11.712, Cited=0, 29620360].
- Walsh CT, Erion MD, Walts AE, ..., Berchtold GA (1987) Chorismate aminations: partial purification of Escherichia coli
PABA synthase and mechanistic comparison with anthranilate synthase. Biochemistry. [IF=0.753, Cited=14, 3311153].
- Walsh CT, Orme-Johnson WH (1987) Nickel enzymes. Biochemistry. [IF=0.753, Cited=26, 3311157].
- Stoll VS, Simpson SJ, Krauth-Siegel RL, ..., Pai EF (1997) Glutathione reductase turned into trypanothione reductase:
structural analysis of an engineered change in substrate specificity. Biochemistry. [IF=0.753, Cited=26, 9174360].
- Walsh CT (2014) Biological matching of chemical reactivity: pairing indole nucleophilicity with electrophilic
isoprenoids. ACS Chemical Biology. [IF=0.963, Cited=24, 25303280].
- Tran HL, Lexa KW, Julien O, ..., Wells JA (2017) Structure-Activity Relationship and Molecular Mechanics Reveal the
Importance of Ring Entropy in the Biosynthesis and Activity of a Natural Product. Journal of the American Chemical
Society. [IF=2.573, Cited=23, 28170244].
- Medema MH, Kottmann R, Yilmaz P, ..., Glöckner FO (2015) Minimum Information about a Biosynthetic Gene cluster. Nature
Chemical Biology. [IF=2.623, Cited=428, 26284661].
- Walsh CT (2015) A chemocentric view of the natural product inventory. Nature Chemical Biology. [IF=2.623, Cited=37, 26284660].
- Walsh CT (2017) Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation
antibiotic scaffolds? Natural Product Reports. [IF=3.292, Cited=4, 28513710].
- Walsh CT (2019) Biologically generated carbon dioxide: nature's versatile chemical strategies for carboxy lyases.
Natural Product Reports. [IF=3.292, Cited=12, 31074473].
- Walsh CT (2023) Tailoring enzyme strategies and functional groups in biosynthetic pathways. Natural Product Reports.
[IF=3.292, Cited=4, 36268810].
- Walsh CT (2016) Insights into the chemical logic and enzymatic machinery of NRPS assembly lines. Natural Product
Reports. [IF=3.292, Cited=79, 26175103].
- Lowry B, Walsh CT, Khosla C (2015) In Vitro Reconstitution of Metabolic Pathways: Insights into Nature's Chemical
Logic. Synlett. [IF=0.473, Cited=10, 26207083].
- Butcher RA, Schroeder FC, Fischbach MA, ..., Clardy J (2007) The identification of bacillaene, the product of the PksX
megacomplex in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=147, 17234808].
- Zhang W, Ostash B, Walsh CT (2010) Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl
nucleoside antibiotics. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=54, 20826445].
- Short SA, Kaback HR, Kaczorowski G, ..., Silverstein SC (1974) Determination of the absolute number of Escherichia coli
membrane vesicles that catalyze active transport. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=16, 4612538].
- Peiser GD, Wang TT, Hoffman NE, ..., Walsh CT (1984) Formation of cyanide from carbon 1 of
1-aminocyclopropane-1-carboxylic acid during its conversion to ethylene. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=103, 16593463].
- Reeve JN, Beckler GS, Cram DS, ..., Walsh CT (1989) A hydrogenase-linked gene in Methanobacterium thermoautotrophicum
strain delta H encodes a polyferredoxin. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=55, 2654933].
- Ke HM, Zydowsky LD, Liu J, Walsh CT (1991) Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A
resolution. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=88, 1946361].
- Swanson SK, Born T, Zydowsky LD, ..., Rusnak F (1992) Cyclosporin-mediated inhibition of bovine calcineurin by
cyclophilins A and B. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=102, 1315036].
- Rehemtulla A, Roth DA, Wasley LC, ..., Kaufman RJ (1993) In vitro and in vivo functional characterization of bovine
vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=26, 8506307].
- Winkler DG, Park I, Kim T, ..., Shin J (1993) Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the
tyrosine kinase p56lck. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=56, 8506364].
- Roth DA, Rehemtulla A, Kaufman RJ, ..., Furie BC (1993) Expression of bovine vitamin K-dependent carboxylase activity in
baculovirus-infected insect cells. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=16, 8378308].
- Bennett AM, Tang TL, Sugimoto S, ..., Neel BG (1994) Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth
factor receptor beta to Ras. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=203, 8041791].
- Park I, Chung J, Walsh CT, ..., Shin J (1995) Phosphotyrosine-independent binding of a 62-kDa protein to the src
homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=62, 8618896].
- Fan C, Moews PC, Shi Y, ..., Knox JR (1995) A common fold for peptide synthetases cleaving ATP to ADP: glutathione
synthetase and D-alanine:d-alanine ligase of Escherichia coli. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=66, 7862655].
- Kharbanda S, Bharti A, Pei D, ..., Kufe D (1996) The stress response to ionizing radiation involoves c-Abl-dependent
phosphorylation of SHPTP1. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=55, 8692915].
- Lessard IA, Walsh CT (1999) VanX, a bacterial D-alanyl-D-alanine dipeptidase: resistance, immunity, or survival
function? Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=40, 10500118].
- Morrongiello JR, Walsh CT, Gray CA, ..., Crook DA (2014) Environmental change drives long-term recruitment and growth
variation in an estuarine fish. Global Change Biology. [IF=3.007, Cited=3, 24510897].
- Arthur M, Molinas C, Bugg TD, ..., Courvalin P (1992) Evidence for in vivo incorporation of D-lactate into peptidoglycan
precursors of vancomycin-resistant enterococci. Antimicrobial Agents and Chemotherapy. [IF=1.175, Cited=69, 1503450].
- Dorfman T, Weimann A, Borsetti A, ..., Göttlinger HG (1997) Active-site residues of cyclophilin A are crucial for its
incorporation into human immunodeficiency virus type 1 virions. Journal of Virology. [IF=1.075, Cited=38, 9261445].
- Chen YC, Peoples OP, Walsh CT (1988) Acinetobacter cyclohexanone monooxygenase: gene cloning and sequence determination.
Journal of Bacteriology. [IF=0.898, Cited=72, 3338974].
- Haldimann A, Fisher SL, Daniels LL, ..., Wanner BL (1997) Transcriptional regulation of the Enterococcus faecium BM4147
vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12. Journal of
Bacteriology. [IF=0.898, Cited=44, 9294451].
- Walsh CT (2017) At the Intersection of Chemistry, Biology, and Medicine. Annual Review of Biochemistry. [IF=5.273,
Cited=1, 28125288].
- Walsh CT, Sandstead HH, Prasad AS, ..., Fraker PJ (1994) Zinc: health effects and research priorities for the 1990s.
Environmental Health Perspectives. [IF=2.06, Cited=152, 7925188].
- Taylor MD, van der Meulen DE, Ives MC, ..., Gray CA (2014) Shock, stress or signal? Implications of freshwater flows for
a top-level estuarine predator. PLoS ONE. [IF=1.253, Cited=2, 24752585].
Publication with MISSING institution:
- Keating TA, Ehmann DE, Kohli RM, ..., Walsh CT (2001) Chain termination steps in nonribosomal peptide synthetase
assembly lines: directed acyl-S-enzyme breakdown in antibiotic and siderophore biosynthesis. ChemBioChem. [IF=0.691,
Cited=44, 11828432].
- Forbes AJ, Mazur MT, Patel HM, ..., Kelleher NL (2001) Toward efficient analysis of >70 kDa proteins with 100% sequence
coverage. Proteomics. [IF=0.795, Cited=33, 11683509].
- Morrison JF, Walsh CT (1988) The behavior and significance of slow-binding enzyme inhibitors. None. [IF=None,
Cited=468, 3281418].
- O'Connor SE, Walsh CT, Liu F (2003) Biosynthesis of epothilone intermediates with alternate starter units: engineering
polyketide-nonribosomal interfaces. Angewandte Chemie - International Edition. [IF=2.456, Cited=17, 12949868].
- Freel Meyers CL, Oberthür M, Xu H, ..., Walsh CT (2004) Characterization of NovP and NovN: completion of novobiocin
biosynthesis by sequential tailoring of the noviosyl ring. Angewandte Chemie - International Edition. [IF=2.456,
Cited=24, 14694473].
- Sieber SA, Tao J, Walsh CT, Marahiel MA (2004) Peptidyl thiophenols as substrates for nonribosomal peptide cyclases.
Angewandte Chemie - International Edition. [IF=2.456, Cited=28, 14735544].
- Hubbard BK, Walsh CT (2003) Vancomycin assembly: nature's way. Angewandte Chemie - International Edition. [IF=2.456,
Cited=135, 12596194].
- Yeh E, Kohli RM, Bruner SD, Walsh CT (2004) Type II thioesterase restores activity of a NRPS module stalled with an
aminoacyl-S-enzyme that cannot be elongated. ChemBioChem. [IF=0.691, Cited=71, 15368584].
- Vaillancourt FH, Vosburg DA, Walsh CT (2006) Dichlorination and bromination of a threonyl-S-carrier protein by the non-
heme Fe(II) halogenase SyrB2. ChemBioChem. [IF=0.691, Cited=18, 16528784].
- Aron ZD, Fortin PD, Calderone CT, Walsh CT (2007) FenF: servicing the Mycosubtilin synthetase assembly line in trans.
ChemBioChem. [IF=0.691, Cited=13, 17330903].
- Balibar CJ, Walsh CT (2008) From thioesters to amides and back: condensation domain reversibility in the biosynthesis of
vibriobactin. ChemBioChem. [IF=0.691, Cited=4, 18022888].
- Strieker M, Essen LO, Walsh CT, Marahiel MA (2008) Non-heme hydroxylase engineering for simple enzymatic synthesis of
L-threo-hydroxyaspartic acid. ChemBioChem. [IF=0.691, Cited=10, 18213565].
- Nolan EM, Walsh CT (2009) How nature morphs peptide scaffolds into antibiotics. ChemBioChem. [IF=0.691, Cited=45, 19058272].
- Altmann KH, Buchner J, Kessler H, ..., Walsh CT (2009) The state of the art of chemical biology. ChemBioChem. [IF=0.691,
Cited=16, 19115274].
- Neumann CS, Jiang W, Heemstra JR, ..., Walsh CT (2012) Biosynthesis of piperazic acid via N5-hydroxy-ornithine in
Kutzneria spp. 744. ChemBioChem. [IF=0.691, Cited=32, 22522643].
- Li B, Forseth RR, Bowers AA, ..., Walsh CT (2012) A backup plan for self-protection: S-methylation of holomycin
biosynthetic intermediates in Streptomyces clavuligerus. ChemBioChem. [IF=0.691, Cited=27, 23097183].
- Gerken T, Walsh CT (2013) Cloning and sequencing of the chaetocin biosynthetic gene cluster. ChemBioChem. [IF=0.691,
Cited=12, 24123808].
- Browne TR, Szabo GK, Walsh CT, ..., Evans BA (1990) New pharmacokinetic methods. II: Determination of the presence or
absence of product inhibition in drugs with nonlinear pharmacokinetics. Journal of Clinical Pharmacology. [IF=0.95,
Cited=2, 2391390].
- Reichert J, Sakaitani M, Walsh CT (1992) Characterization of EntF as a serine-activating enzyme. Protein Science.
[IF=1.97, Cited=26, 1338974].
- Zydowsky LD, Ho SI, Baker CH, ..., Walsh CT (1992) Overexpression, purification, and characterization of yeast
cyclophilins A and B. Protein Science. [IF=1.97, Cited=10, 1304384].
- Nadeau K, Sullivan MA, Bradley M, ..., Walsh CT (1992) 83-kilodalton heat shock proteins of trypanosomes are potent
peptide-stimulated ATPases. Protein Science. [IF=1.97, Cited=18, 1304385].
- Zydowsky LD, Etzkorn FA, Chang HY, ..., Walsh CT (1992) Active site mutants of human cyclophilin A separate peptidyl-
prolyl isomerase activity from cyclosporin A binding and calcineurin inhibition. Protein Science. [IF=1.97, Cited=174, 1338979].
- Lee JP, Cho H, Bannwarth W, ..., Walsh CT (1992) NMR analysis of regioselectivity in dephosphorylation of a
triphosphotyrosyl dodecapeptide autophosphorylation site of the insulin receptor by a catalytic fragment of LAR
phosphotyrosine phosphatase. Protein Science. [IF=1.97, Cited=5, 1303753].
- Cho H, Krishnaraj R, Itoh M, ..., Walsh CT (1993) Substrate specificities of catalytic fragments of protein tyrosine
phosphatases (HPTP beta, LAR, and CD45) toward phosphotyrosylpeptide substrates and thiophosphotyrosylated peptides as
inhibitors. Protein Science. [IF=1.97, Cited=32, 8318901].
- Wright GD, Walsh CT (1993) Identification of a common protease-sensitive region in D-alanyl-D-alanine and D-alanyl-D-
lactate ligases and photoaffinity labeling with 8-azido ATP. Protein Science. [IF=1.97, Cited=6, 8251948].
- Benson TE, Walsh CT, Hogle JM (1994) Crystallization and preliminary X-ray crystallographic studies of UDP-N-
acetylenolpyruvylglucosamine reductase. Protein Science. [IF=1.97, Cited=6, 7920261].
- Jakimowicz P, Tello M, Meyers CLF, ..., Lawson DM (2006) The 1.6-A resolution crystal structure of NovW: a
4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides. Proteins:
Structure, Function and Bioinformatics. [IF=0.897, Cited=9, 16411240].
- Ma H, Bloom LM, Dakin SE, ..., Botstein D (1989) The 15 N-terminal amino acids of hexokinase II are not required for in
vivo function: analysis of a truncated form of hexokinase II in Saccharomyces cerevisiae. Proteins: Structure, Function
and Bioinformatics. [IF=0.897, Cited=7, 2674934].
- Yuan W, Jia Y, Tian J, ..., Stubbe J (2001) Class I and III polyhydroxyalkanoate synthases from Ralstonia eutropha and
Allochromatium vinosum: characterization and substrate specificity studies. Archives of Biochemistry and Biophysics.
[IF=0.874, Cited=66, 11566031].
- Heddle JG, Blance SJ, Zamble DB, ..., Maxwell A (2001) The antibiotic microcin B17 is a DNA gyrase poison:
characterisation of the mode of inhibition. Journal of Molecular Biology. [IF=1.281, Cited=73, 11292337].
- Vosburg DA, Walsh CT (2005) Natural product biosynthetic assembly lines: prospects and challenges for reprogramming.
None. [IF=None, Cited=1, 15645725].
- Kiener A, Orme-Johnson WH, Walsh CT (1988) Reversible conversion of coenzyme F420 to the 8-OH-AMP and 8-OH-GMP esters,
F390-A and F390-G, on oxygen exposure and reestablishment of anaerobiosis in Methanobacterium thermoautotrophicum.
Archives of Microbiology. [IF=0.761, Cited=14, 3178397].
- Ritsema T, Gehring AM, Stuitje AR, ..., Spaink HP (1998) Functional analysis of an interspecies chimera of acyl carrier
proteins indicates a specialized domain for protein recognition. None. [IF=None, Cited=20, 9604887].
- Frueh DP, Vosburg DA, Walsh CT, Wagner G (2006) Determination of all nOes in 1H-13C-Me-ILV-U-2H-15N proteins with two
time-shared experiments. Journal of Biomolecular NMR. [IF=0.794, Cited=18, 16505962].
- Frueh DP, Leed A, Arthanari H, ..., Wagner G (2009) Time-shared HSQC-NOESY for accurate distance constraints measured at
high-field in (15)N-(13)C-ILV methyl labeled proteins. Journal of Biomolecular NMR. [IF=0.794, Cited=8, 19728110].
- Walsh CT, Spector LB (1971) The glucose-glucose 6-phosphate exchange catalyzed by yeast hexokinase. Archives of
Biochemistry and Biophysics. [IF=0.874, Cited=7, 5123138].
- Walsh CT (1982) The influence of age on the gastrointestinal absorption of mercuric chloride and methyl mercury chloride
in the rat. Environmental Research. [IF=1.664, Cited=22, 6211348].
- Neri P, Gemmecker G, Zydowsky LD, ..., Fesik SW (1991) NMR studies of [U-13C]cyclosporin A bound to human cyclophilin B.
FEBS Letters. [IF=0.871, Cited=6, 1915874].
- Krauth-Siegel RL, Sticherling C, Jöst I, ..., Lantwin CB (1993) Crystallization and preliminary crystallographic
analysis of trypanothione reductase from Trypanosoma cruzi, the causative agent of Chagas' disease. FEBS Letters.
[IF=0.871, Cited=17, 8428618].
- Knox JR, Liu HS, Walsh CT, Zawadzke LE (1989) D-alanine-D-alanine ligase (ADP) from Salmonella typhimurium.
Overproduction, purification, crystallization and preliminary X-ray analysis. Journal of Molecular Biology. [IF=1.281,
Cited=4, 2648004].
- Walsh CT, Feierabend JF, Levine RR (1975) The effect of lincomycin on the excretion of diethylstilbestrol and its
uterotrophic action in rats. Life Sciences. [IF=1.121, Cited=1, 1142994].
- Walsh CT, Ryden EB (1984) The effect of chronic ingestion of lead on gastrointestinal transit in rats. Toxicology and
Applied Pharmacology. [IF=0.883, Cited=6, 6474476].
- Walsh CT, Harnett KM (1986) Inhibitory effect of lead acetate on contractility of longitudinal smooth muscle from rat
ileum. Toxicology and Applied Pharmacology. [IF=0.883, Cited=5, 3952751].
- Sullivan FX, Walsh CT (1991) Cloning, sequencing, overproduction and purification of trypanothione reductase from
Trypanosoma cruzi. Molecular and Biochemical Parasitology. [IF=0.541, Cited=56, 2011150].
- Ryden EB, Walsh CT (1987) The effect of lead on cholinergic contractile function in the rat forestomach. Toxicology.
[IF=0.909, Cited=3, 3299876].
- Payne G, Stolz LA, Pei D, ..., Walsh CT (1994) The phosphopeptide-binding specificity of Src family SH2 domains. None.
[IF=None, Cited=17, 9383377].
- Shaw-Reid CA, Kelleher NL, Losey HC, ..., Walsh CT (1999) Assembly line enzymology by multimodular nonribosomal peptide
synthetases: the thioesterase domain of E. coli EntF catalyzes both elongation and cyclolactonization. None. [IF=None,
Cited=96, 10375542].
- Lessard IA, Walsh CT (1999) Mutational analysis of active-site residues of the enterococcal D-ala-D-Ala dipeptidase VanX
and comparison with Escherichia coli D-ala-D-Ala ligase and D-ala-D-Ala carboxypeptidase VanY. None. [IF=None,
Cited=24, 10074467].
- Fujimori DG, Walsh CT (2007) What's new in enzymatic halogenations. Current Opinion in Chemical Biology. [IF=1.51,
Cited=33, 17881282].
- Walsh CT (2022) Propofol: Milk of Amnesia. Cell. [IF=8.479, Cited=2, 36493757].
- Hicks LM, O'Connor SE, Mazur MT, ..., Kelleher NL (2004) Mass spectrometric interrogation of thioester-bound
intermediates in the initial stages of epothilone biosynthesis. None. [IF=None, Cited=24, 15123262].
- Tseng CC, Vaillancourt FH, Bruner SD, Walsh CT (2004) DpgC is a metal- and cofactor-free 3,5-dihydroxyphenylacetyl-CoA
1,2-dioxygenase in the vancomycin biosynthetic pathway. None. [IF=None, Cited=19, 15380180].
- Liu F, Garneau S, Walsh CT (2004) Hybrid nonribosomal peptide-polyketide interfaces in epothilone biosynthesis: minimal
requirements at N and C termini of EpoB for elongation. None. [IF=None, Cited=21, 15556004].
- Yeh E, Lin H, Clugston SL, ..., Walsh CT (2004) Enhanced macrocyclizing activity of the thioesterase from tyrocidine
synthetase in presence of nonionic detergent. None. [IF=None, Cited=15, 15556008].
- Lin H, Thayer DA, Wong CH, Walsh CT (2004) Macrolactamization of glycosylated peptide thioesters by the thioesterase
domain of tyrocidine synthetase. None. [IF=None, Cited=25, 15610847].
- Kruger RG, Lu W, Oberthür M, ..., Walsh CT (2005) Tailoring of glycopeptide scaffolds by the acyltransferases from the
teicoplanin and A-40,926 biosynthetic operons. None. [IF=None, Cited=24, 15664522].
- Lu W, Leimkuhler C, Gatto GJ, ..., Walsh CT (2005) AknT is an activating protein for the glycosyltransferase AknS in
L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. None. [IF=None, Cited=43, 15911373].
- Yin J, Lin AJ, Buckett PD, ..., Walsh CT (2005) Single-cell FRET imaging of transferrin receptor trafficking dynamics by
Sfp-catalyzed, site-specific protein labeling. None. [IF=None, Cited=34, 16183024].
- Balibar CJ, Vaillancourt FH, Walsh CT (2005) Generation of D amino acid residues in assembly of arthrofactin by dual
condensation/epimerization domains. None. [IF=None, Cited=84, 16298298].
- Zhou Z, Lai JR, Walsh CT (2006) Interdomain communication between the thiolation and thioesterase domains of EntF
explored by combinatorial mutagenesis and selection. None. [IF=None, Cited=23, 16931336].
- Ueki M, Galonić DP, Vaillancourt FH, ..., Walsh CT (2006) Enzymatic generation of the antimetabolite gamma,gamma-
dichloroaminobutyrate by NRPS and mononuclear iron halogenase action in a streptomycete. None. [IF=None, Cited=48, 17114000].
- Singh GM, Vaillancourt FH, Yin J, Walsh CT (2007) Characterization of SyrC, an aminoacyltransferase shuttling threonyl
and chlorothreonyl residues in the syringomycin biosynthetic assembly line. None. [IF=None, Cited=30, 17254950].
- Yin J, Straight PD, Hrvatin S, ..., Walsh CT (2007) Genome-wide high-throughput mining of natural-product biosynthetic
gene clusters by phage display. None. [IF=None, Cited=24, 17379145].
- Balibar CJ, Garneau-Tsodikova S, Walsh CT (2007) Covalent CouN7 enzyme intermediate for acyl group shuttling in
aminocoumarin biosynthesis. None. [IF=None, Cited=13, 17584615].
- Calderone CT, Iwig DF, Dorrestein PC, ..., Walsh CT (2007) Incorporation of nonmethyl branches by isoprenoid-like logic:
multiple beta-alkylation events in the biosynthesis of myxovirescin A1. None. [IF=None, Cited=43, 17656320].
- Neumann CS, Fujimori DG, Walsh CT (2008) Halogenation strategies in natural product biosynthesis. None. [IF=None,
Cited=159, 18291314].
- Imker HJ, Krahn D, Clerc J, ..., Walsh CT (2010) N-acylation during glidobactin biosynthesis by the tridomain
nonribosomal peptide synthetase module GlbF. None. [IF=None, Cited=54, 21035730].
- Crawford JM, Mahlstedt SA, Malcolmson SJ, ..., Walsh CT (2011) Dihydrophenylalanine: a prephenate-derived Photorhabdus
luminescens antibiotic and intermediate in dihydrostilbene biosynthesis. None. [IF=None, Cited=7, 21944749].
- Goldman PJ, Ryan KS, Hamill MJ, ..., Drennan CL (2012) An unusual role for a mobile flavin in StaC-like indolocarbazole
biosynthetic enzymes. None. [IF=None, Cited=21, 22840773].
- Young TS, Dorrestein PC, Walsh CT (2012) Codon randomization for rapid exploration of chemical space in thiopeptide
antibiotic variants. None. [IF=None, Cited=46, 23261603].
- Gao X, Jiang W, Jiménez-Osés G, ..., Walsh CT (2013) An iterative, bimodular nonribosomal peptide synthetase that
converts anthranilate and tryptophan into tetracyclic asperlicins. None. [IF=None, Cited=10, 23890005].
- Gómez García I, Stevenson CEM, Usón I, ..., Lawson DM (2009) The crystal structure of the novobiocin biosynthetic enzyme
NovP: the first representative structure for the TylF O-methyltransferase superfamily. Journal of Molecular Biology.
[IF=1.281, Cited=23, 19857499].
- Lambalot RH, Walsh CT (1997) Holo-[acyl-carrier-protein] synthase of Escherichia coli. None. [IF=None, Cited=23, 9211277].
- Furie BC, Kuliopulos A, Roth DA, ..., Furie B (1997) Purification of native bovine carboxylase and expression and
purification of recombinant bovine carboxylase. None. [IF=None, Cited=3, 9330299].
- Ke H, Mayrose D, Belshaw PJ, ..., Walsh CT (1994) Crystal structures of cyclophilin A complexed with cyclosporin A and
N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A. Structure. [IF=1.155, Cited=44, 8075981].
- Kuzin AP, Sun T, Jorczak-Baillass J, ..., Knox JR (2000) Enzymes of vancomycin resistance: the structure of D-alanine-D-
lactate ligase of naturally resistant Leuconostoc mesenteroides. Structure. [IF=1.155, Cited=25, 10801495].
- Mulichak AM, Losey HC, Walsh CT, Garavito RM (2001) Structure of the UDP-glucosyltransferase GtfB that modifies the
heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics. Structure. [IF=1.155, Cited=110, 11470430].
- Bruner SD, Weber T, Kohli RM, ..., Stubbs MT (2002) Structural basis for the cyclization of the lipopeptide antibiotic
surfactin by the thioesterase domain SrfTE. Structure. [IF=1.155, Cited=131, 12005429].
- Benson TE, Walsh CT, Hogle JM (1996) The structure of the substrate-free form of MurB, an essential enzyme for the
synthesis of bacterial cell walls. Structure. [IF=1.155, Cited=37, 8805513].
- Ehmann DE, Trauger JW, Stachelhaus T, Walsh CT (2000) Aminoacyl-SNACs as small-molecule substrates for the condensation
domains of nonribosomal peptide synthetases. None. [IF=None, Cited=53, 11033080].
- Hubbard BK, Thomas MG, Walsh CT (2000) Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid
constituent of peptide antibiotics. None. [IF=None, Cited=76, 11137816].
- Healy VL, Lessard IA, Roper DI, ..., Walsh CT (2000) Vancomycin resistance in enterococci: reprogramming of the D-ala-D-
Ala ligases in bacterial peptidoglycan biosynthesis. None. [IF=None, Cited=68, 10801476].
- Healy VL, Mullins LS, Li X, ..., Walsh CT (2000) D-Ala-D-X ligases: evaluation of D-alanyl phosphate intermediate by
MIX, PIX and rapid quench studies. None. [IF=None, Cited=13, 10903933].
- Cane DE, Walsh CT (1999) The parallel and convergent universes of polyketide synthases and nonribosomal peptide
synthetases. None. [IF=None, Cited=147, 10631508].
- Chen H, Walsh CT (2001) Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme
tyrosyl-S-NovH by a cytochrome P450 NovI. None. [IF=None, Cited=83, 11325587].
- Chen H, O'Connor S, Cane DE, Walsh CT (2001) Epothilone biosynthesis: assembly of the methylthiazolylcarboxy starter
unit on the EpoB subunit. None. [IF=None, Cited=36, 11564558].
- Chen H, Hubbard BK, O'Connor SE, Walsh CT (2002) Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin
antibiotics. None. [IF=None, Cited=93, 11841943].
- Thomas MG, Burkart MD, Walsh CT (2002) Conversion of L-proline to pyrrolyl-2-carboxyl-S-PCP during undecylprodigiosin
and pyoluteorin biosynthesis. None. [IF=None, Cited=93, 11880032].
- Miller DA, Luo L, Hillson N, ..., Walsh CT (2002) Yersiniabactin synthetase: a four-protein assembly line producing the
nonribosomal peptide/polyketide hybrid siderophore of Yersinia pestis. None. [IF=None, Cited=100, 11927258].
- Sieber SA, Linne U, Hillson NJ, ..., Marahiel MA (2002) Evidence for a monomeric structure of nonribosomal Peptide
synthetases. None. [IF=None, Cited=29, 12323374].
- Losey HC, Jiang J, Biggins JB, ..., Walsh CT (2002) Incorporation of glucose analogs by GtfE and GtfD from the
vancomycin biosynthetic pathway to generate variant glycopeptides. None. [IF=None, Cited=82, 12498883].
- Lambalot RH, Gehring AM, Flugel RS, ..., Walsh CT (1996) A new enzyme superfamily - the phosphopantetheinyl
transferases. None. [IF=None, Cited=473, 8939709].
- Lin CH, Chen S, Kwon DS, ..., Walsh CT (1997) Aldehyde and phosphinate analogs of glutathione and
glutathionylspermidine: potent, selective binding inhibitors of the E. coli bifunctional glutathionylspermidine
synthetase/amidase. None. [IF=None, Cited=12, 9384533].
- Gehring AM, Lambalot RH, Vogel KW, ..., Walsh CT (1997) Ability of Streptomyces spp. acyl carrier proteins and coenzyme
A analogs to serve as substrates in vitro for E. coli holo-ACP synthase. None. [IF=None, Cited=58, 9070424].
- Lessard IA, Pratt SD, McCafferty DG, ..., Walsh CT (1998) Homologs of the vancomycin resistance D-Ala-D-Ala dipeptidase
VanX in Streptomyces toyocaensis, Escherichia coli and Synechocystis: attributes of catalytic efficiency,
stereoselectivity and regulation with implications for function. None. [IF=None, Cited=43, 9751644].
- Belshaw PJ, Roy RS, Kelleher NL, Walsh CT (1998) Kinetics and regioselectivity of peptide-to-heterocycle conversions by
microcin B17 synthetase. None. [IF=None, Cited=27, 9662507].
- Gehring AM, DeMoll E, Fetherston JD, ..., Perry RD (1998) Iron acquisition in plague: modular logic in enzymatic
biogenesis of yersiniabactin by Yersinia pestis. None. [IF=None, Cited=136, 9818149].
- Quadri LE, Sello J, Keating TA, ..., Walsh CT (1998) Identification of a Mycobacterium tuberculosis gene cluster
encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin. None. [IF=None,
Cited=269, 9831524].
- Healy VL, Park IS, Walsh CT (1998) Active-site mutants of the VanC2 D-alanyl-D-serine ligase, characteristic of one
vancomycin-resistant bacterial phenotype, revert towards wild-type D-alanyl-D-alanine ligases. None. [IF=None,
Cited=15, 9545431].
- Roy RS, Kim S, Baleja JD, Walsh CT (1998) Role of the microcin B17 propeptide in substrate recognition: solution
structure and mutational analysis of McbA1-26. None. [IF=None, Cited=33, 9545435].
- Sinha Roy R, Kelleher NL, Milne JC, Walsh CT (1999) In vivo processing and antibiotic activity of microcin B17 analogs
with varying ring content and altered bisheterocyclic sites. None. [IF=None, Cited=31, 10322125].
- Roy RS, Allen O, Walsh CT (1999) Expressed protein ligation to probe regiospecificity of heterocyclization in the
peptide antibiotic microcin B17. None. [IF=None, Cited=25, 10574779].
- Keating TA, Walsh CT (1999) Initiation, elongation, and termination strategies in polyketide and polypeptide antibiotic
biosynthesis. Current Opinion in Chemical Biology. [IF=1.51, Cited=78, 10508662].
- Privalsky TM, Soohoo AM, Wang J, ..., Khosla C (2021) Prospects for Antibacterial Discovery and Development. Journal of
the American Chemical Society. [IF=2.573, Cited=17, 34860516].
- Yamada M, Kuliopulos A, Nelson NP, ..., Walsh CT (1995) Localization of the factor IX propeptide binding site on
recombinant vitamin K dependent carboxylase using benzoylphenylalanine photoaffinity peptide inactivators. Biochemistry.
[IF=0.753, Cited=20, 7819240].
- Wu Z, Wright GD, Walsh CT (1995) Overexpression, purification, and characterization of VanX, a D-, D-dipeptidase which
is essential for vancomycin resistance in Enterococcus faecium BM4147. Biochemistry. [IF=0.753, Cited=71, 7873524].
- Shi Y, Walsh CT (1995) Active site mapping of Escherichia coli D-Ala-D-Ala ligase by structure-based mutagenesis.
Biochemistry. [IF=0.753, Cited=40, 7893688].
- Benson TE, Marquardt JL, Marquardt AC, ..., Walsh CT (1993) Overexpression, purification, and mechanistic study of UDP-
N-acetylenolpyruvylglucosamine reductase. Biochemistry. [IF=0.753, Cited=51, 8448160].
- Roux B, Walsh CT (1993) p-Aminobenzoate synthesis in Escherichia coli: mutational analysis of three conserved amino acid
residues of the amidotransferase PabA. Biochemistry. [IF=0.753, Cited=10, 8096767].
- Wright GD, Holman TR, Walsh CT (1993) Purification and characterization of VanR and the cytosolic domain of VanS: a two-
component regulatory system required for vancomycin resistance in Enterococcus faecium BM4147. Biochemistry. [IF=0.753,
Cited=81, 8494882].
- Clubb RT, Thanabal V, Fejzo J, ..., Wagner G (1993) Secondary structure and backbone resonance assignments of the
periplasmic cyclophilin type peptidyl-prolyl isomerase from Escherichia coli. Biochemistry. [IF=0.753, Cited=3, 8518284].
- Rennex D, Cummings RT, Pickett M, ..., Bradley M (1993) Role of tyrosine residues in Hg(II) detoxification by mercuric
reductase from Bacillus sp. strain RC607. Biochemistry. [IF=0.753, Cited=12, 8338845].
- Bugg TD, Wright GD, Dutka-Malen S, ..., Walsh CT (1991) Molecular basis for vancomycin resistance in Enterococcus
faecium BM4147: biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA.
Biochemistry. [IF=0.753, Cited=336, 1931965].
- Cho H, Ramer SE, Itoh M, ..., Walsh CT (1992) Catalytic domains of the LAR and CD45 protein tyrosine phosphatases from
Escherichia coli expression systems: purification and characterization for specificity and mechanism. Biochemistry.
[IF=0.753, Cited=36, 1370625].
- Cummings RT, Walsh CT (1992) Interaction of Tn501 mercuric reductase and dihydroflavin adenine dinucleotide anion with
metal ions: implications for the mechanism of mercuric reductase mediated Hg(II) reduction. Biochemistry. [IF=0.753,
Cited=5, 1310417].
- Moore MJ, Miller SM, Miller S, ..., Walsh CT (1992) C-terminal cysteines of Tn501 mercuric ion reductase. Biochemistry.
[IF=0.753, Cited=19, 1531297].
- Leichus BN, Bradley M, Nadeau K, ..., Blanchard JS (1992) Kinetic isotope effect analysis of the reaction catalyzed by
Trypanosoma congolense trypanothione reductase. Biochemistry. [IF=0.753, Cited=8, 1633154].
- Roux B, Walsh CT (1992) p-aminobenzoate synthesis in Escherichia coli: kinetic and mechanistic characterization of the
amidotransferase PabA. Biochemistry. [IF=0.753, Cited=21, 1637823].
- Kuliopulos A, Hubbard BR, Lam Z, ..., Walsh CT (1992) Dioxygen transfer during vitamin K dependent carboxylase
catalysis. Biochemistry. [IF=0.753, Cited=4, 1510957].
- Kuliopulos A, Cieurzo CE, Furie B, ..., Walsh CT (1992) N-bromoacetyl-peptide substrate affinity labeling of vitamin K
dependent carboxylase. Biochemistry. [IF=0.753, Cited=6, 1390725].
- Etzkorn FA, Chang ZY, Stolz LA, Walsh CT (1994) Cyclophilin residues that affect noncompetitive inhibition of the
protein serine phosphatase activity of calcineurin by the cyclophilin.cyclosporin A complex. Biochemistry. [IF=0.753,
Cited=41, 8117697].
- Nadeau K, Nadler SG, Saulnier M, ..., Walsh CT (1994) Quantitation of the interaction of the immunosuppressant
deoxyspergualin and analogs with Hsc70 and Hsp90. Biochemistry. [IF=0.753, Cited=62, 8117717].
- Clubb RT, Ferguson SB, Walsh CT, Wagner G (1994) Three-dimensional solution structure of Escherichia coli periplasmic
cyclophilin. Biochemistry. [IF=0.753, Cited=49, 8130188].
- Comess KM, Shewchuk LM, Ivanetich K, Walsh CT (1994) Construction of a synthetic gene for the metalloregulatory protein
MerR and analysis of regionally mutated proteins for transcriptional regulation. Biochemistry. [IF=0.753, Cited=13, 8155633].
- Holman TR, Wu Z, Wanner BL, Walsh CT (1994) Identification of the DNA-binding site for the phosphorylated VanR protein
required for vancomycin resistance in Enterococcus faecium. Biochemistry. [IF=0.753, Cited=63, 8161518].
- Fejzo J, Etzkorn FA, Clubb RT, ..., Wagner G (1994) The mutant Escherichia coli F112W cyclophilin binds cyclosporin A in
nearly identical conformation as human cyclophilin. Biochemistry. [IF=0.753, Cited=12, 8180197].
- Chu YH, Lees WJ, Stassinopoulos A, Walsh CT (1994) Using affinity capillary electrophoresis to determine binding
stoichiometries of protein-ligand interactions. Biochemistry. [IF=0.753, Cited=52, 8075061].
- Brown ED, Marquardt JL, Lee JP, ..., Anderson KS (1994) Detection and characterization of a phospholactoyl-enzyme adduct
in the reaction catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase, MurZ. Biochemistry. [IF=0.753, Cited=29, 8075064].
- Marquardt JL, Brown ED, Lane WS, ..., Walsh CT (1994) Kinetics, stoichiometry, and identification of the reactive
thiolate in the inactivation of UDP-GlcNAc enolpyruvoyl transferase by the antibiotic fosfomycin. Biochemistry.
[IF=0.753, Cited=80, 8075065].
- Zawadzke LE, Bugg TD, Walsh CT (1991) Existence of two D-alanine:D-alanine ligases in Escherichia coli: cloning and
sequencing of the ddlA gene and purification and characterization of the DdlA and DdlB enzymes. Biochemistry. [IF=0.753,
Cited=77, 1993184].
- Bugg TD, Dutka-Malen S, Arthur M, ..., Walsh CT (1991) Identification of vancomycin resistance protein VanA as a
D-alanine:D-alanine ligase of altered substrate specificity. Biochemistry. [IF=0.753, Cited=109, 1998664].
- Liu J, Chen CM, Walsh CT (1991) Human and Escherichia coli cyclophilins: sensitivity to inhibition by the
immunosuppressant cyclosporin A correlates with a specific tryptophan residue. Biochemistry. [IF=0.753, Cited=92, 2001362].
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reductase: an alternating sites hypothesis for catalysis. Biochemistry. [IF=0.753, Cited=19, 2001350].
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of glutathione reductase activity in a triple mutant. Biochemistry. [IF=0.753, Cited=22, 2007114].
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enterobactin: sequence of the entF gene, expression and purification of EntF, and analysis of covalent
phosphopantetheine. Biochemistry. [IF=0.753, Cited=94, 1826089].
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trypanothione reductase. Biochemistry. [IF=0.753, Cited=16, 2059620].
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human transmembrane leukocyte antigen related (LAR) protein tyrosine phosphatase from an Escherichia coli expression
system. Biochemistry. [IF=0.753, Cited=34, 1711896].
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a new function for Src homology 2 domains. Biochemistry. [IF=0.753, Cited=108, 7528537].
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enzymes. Biochemistry. [IF=0.753, Cited=5, 6215936].
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2-hydroxycitrate stereoisomers. Biochemistry. [IF=0.753, Cited=1, 6347252].
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alkylation and sequence of the active site peptide. Biochemistry. [IF=0.753, Cited=57, 6412751].
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Crithidia fasciculata. Biochemistry. [IF=0.753, Cited=9, 6087880].
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sequence, enzyme purification, and characterization. Biochemistry. [IF=0.753, Cited=41, 6391537].
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beta-substituted alanines: kinetics, stoichiometry, active site peptide sequencing, and reaction mechanism.
Biochemistry. [IF=0.753, Cited=34, 6439236].
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by D and L isomers of beta-substituted alanines: kinetics, stoichiometry, active site peptide, and mechanistic studies.
Biochemistry. [IF=0.753, Cited=22, 6439237].
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flavoenzyme mercuric ion reductase. Biochemistry. [IF=0.753, Cited=19, 3907703].
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protein sequence determination. Biochemistry. [IF=0.753, Cited=25, 3524676].
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the enzyme encoded by the alr gene. Biochemistry. [IF=0.753, Cited=60, 3524677].
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molecular cloning of the gene, enzyme purification, and characterization. Biochemistry. [IF=0.753, Cited=51, 3015202].
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(1-aminoethyl)phosphonate isomers by isomerization to noncovalent slowly dissociating enzyme-(1-aminoethyl)phosphonate
complexes. Biochemistry. [IF=0.753, Cited=12, 3730360].
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Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases.
Biochemistry. [IF=0.753, Cited=141, 3718941].
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Biochemistry. [IF=0.753, Cited=32, 3542021].
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organomercurial lyase. Biochemistry. [IF=0.753, Cited=43, 3542022].
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deaminase and Bacillus stearothermophilus alanine racemase by slow dissociation behavior. Biochemistry. [IF=0.753,
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Methanobacterium thermoautotrophicum: 1. Purification and characterization. Biochemistry. [IF=0.753, Cited=66, 3663585].
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Methanobacterium thermoautotrophicum: 2. Kinetic and hydrogen-transfer studies. Biochemistry. [IF=0.753, Cited=18, 3663586].
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reductase. Biochemistry. [IF=0.753, Cited=13, 3120769].
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identification of the cleavage site and characterization of the clipped two-domain proteins. Biochemistry. [IF=0.753,
Cited=17, 3327523].
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stearothermophilus: energetic reaction profiles. Biochemistry. [IF=0.753, Cited=15, 3291946].
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gene with purification and characterization of its product, D-alanine:D-alanine ligase (ADP forming). Biochemistry.
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D-alanine:D-alanine ligase (ADP) by (aminoalkyl)phosphinate and aminophosphonate analogues of D-alanine. Biochemistry.
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imine linkage to pyridoxal 5'-phosphate in the enzyme-inhibitor complex by solid-state 15N nuclear magnetic resonance.
Biochemistry. [IF=0.753, Cited=17, 3167024].
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isolation, primary sequence determination, and comparison to glutathione reductase. Biochemistry. [IF=0.753, Cited=42, 3167026].
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(carbonyl group) exchange activity of the acetyl-CoA synthesizing CO dehydrogenase from Clostridium thermoaceticum.
Biochemistry. [IF=0.753, Cited=24, 2905170].
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Biochemistry. [IF=0.753, Cited=17, 2496744].
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mutant enzymes restricted to flavin redox chemistry. Biochemistry. [IF=0.753, Cited=13, 2653436].
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consequences for bacterial detoxification of mercurials. Biochemistry. [IF=0.753, Cited=21, 2540817].
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site of mercuric reductase. Biochemistry. [IF=0.753, Cited=36, 2653437].
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characterization of DNA and mercury (II) binding activities. Biochemistry. [IF=0.753, Cited=34, 2719955].
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repression mutants implicate distinct DNA and mercury(II) binding domains. Biochemistry. [IF=0.753, Cited=31, 2497778].
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stearothermophilus alanine racemase and Salmonella typhimurium D-alanine:D-alanine ligase (ADP-forming). Biochemistry.
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coenzyme A exchange catalyzed by a three-subunit form of the carbon monoxide dehydrogenase/acetyl-CoA synthase from
Clostridium thermoaceticum. Biochemistry. [IF=0.753, Cited=9, 2569891].
- Sullivan FX, Shames SL, Walsh CT (1989) Expression of Trypanosoma congolense trypanothione reductase in Escherichia
coli: overproduction, purification, and characterization. Biochemistry. [IF=0.753, Cited=33, 2669965].
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ramigera: identification of the active-site nucleophile as Cys89, its mutation to Ser89, and kinetic and thermodynamic
characterization of wild-type and mutant enzymes. Biochemistry. [IF=0.753, Cited=48, 2775734].
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indicates that a metal-bridged dimer activates transcription. Biochemistry. [IF=0.753, Cited=24, 2551364].
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2,3-dihydroxybenzoate-AMP ligase: demonstration of enzyme-bound (2,3-dihydroxybenzoyl)adenylate product. Biochemistry.
[IF=0.753, Cited=75, 2531000].
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and conformational constraint of the linker sequence on catalytic efficiency. Biochemistry. [IF=0.753, Cited=6, 2690935].
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synthase (EntC), the first enzyme involved in the biosynthesis of enterobactin from chorismate. Biochemistry. [IF=0.753,
Cited=55, 2139795].
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purification, characterization, and substrate specificity of isochorismatase. Biochemistry. [IF=0.753, Cited=51, 2139796].
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from Escherichia coli. Biochemistry. [IF=0.753, Cited=35, 2186811].
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Cys135 and Cys140 from one subunit and Cys558 and Cys559 from the adjacent subunit: evidence from in vivo and in vitro
heterodimer formation. Biochemistry. [IF=0.753, Cited=22, 2189495].
- Miller SM, Miller S, Massey V, ..., Walsh CT (1990) Use of a site-directed triple mutant to trap intermediates:
demonstration that the flavin C(4a)-thiol adduct and reduced flavin are kinetically competent intermediates in mercuric
ion reductase. Biochemistry. [IF=0.753, Cited=40, 2189497].
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enzyme-inhibitor complex: phosphorylation of an (aminoalkyl)phosphinate inhibitor of D-alanyl-D-alanine ligase by ATP.
Biochemistry. [IF=0.753, Cited=21, 2200515].
- Sakaitani M, Rusnak F, Quinn NR, ..., Walsh CT (1990) Mechanistic studies on trans-2,3-dihydro-2,3-dihydroxybenzoate
dehydrogenase (Ent A) in the biosynthesis of the iron chelator enterobactin. Biochemistry. [IF=0.753, Cited=15, 2144454].
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encoding the subunits of the nickel-containing 8-hydroxy-5-deazaflavin reducing hydrogenase from Methanobacterium
thermoautotrophicum delta H. Biochemistry. [IF=0.753, Cited=48, 2207102].
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D-amino acid dehydrogenase. Biochemistry. [IF=0.753, Cited=3, 6118175].
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acetylenic suicide substrate] 2-hydroxy-3-butynoate. Biochemistry. [IF=0.753, Cited=14, 1268195].
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lactate oxidase and the suicide substrate 2-hydroxy-3-butynoate. Biochemistry. [IF=0.753, Cited=15, 1268196].
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two subunits. Biochemistry. [IF=0.753, Cited=18, 1148170].
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PheATE of gramicidin S synthetase. Biochemistry. [IF=0.753, Cited=17, 11330995].
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halogenase domains in the Curacin A polyketide synthase. ACS Chemical Biology. [IF=0.963, Cited=19, 22103656].
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propargylglycine. Journal of the American Chemical Society. [IF=2.573, Cited=70, 4733835].
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tyrocidine synthetase. Nature. [IF=11.591, Cited=158, 11001063].
- Schiering N, Kabsch W, Moore MJ, ..., Pai EF (1991) Structure of the detoxification catalyst mercuric ion reductase from
Bacillus sp. strain RC607. Nature. [IF=11.591, Cited=86, 2067577].
- Thali M, Bukovsky A, Kondo E, ..., Göttlinger HG (1994) Functional association of cyclophilin A with HIV-1 virions.
Nature. [IF=11.591, Cited=423, 7969495].
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biosynthesis of the microcin C7 antibiotic. EMBO Journal. [IF=2.114, Cited=46, 19494832].
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cyclopropyl amino acid biosynthesis. Nature. [IF=11.591, Cited=148, 16121186].
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syringomycin biosynthesis. Nature. [IF=11.591, Cited=166, 16541079].
- Taga ME, Larsen NA, Howard-Jones AR, ..., Walker GC (2007) BluB cannibalizes flavin to form the lower ligand of vitamin
B12. Nature. [IF=11.591, Cited=104, 17377583].
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lines. Nature. [IF=11.591, Cited=40, 17653193].
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the surfactin synthetase. Nature. [IF=11.591, Cited=83, 18704089].
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peptide synthetase. Nature. [IF=11.591, Cited=93, 18704088].
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like domain. Nature Chemical Biology. [IF=2.623, Cited=91, 22902615].
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and bisprenylation. Nature Chemical Biology. [IF=2.623, Cited=81, 17704773].
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Nature Chemical Biology. [IF=2.623, Cited=189, 16485005].
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the halogenase CytC3. Nature Chemical Biology. [IF=2.623, Cited=155, 17220900].
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Drug Discovery. [IF=18.471, Cited=83, 15520815].
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biosynthesis. None. [IF=None, Cited=45, 7552726].
- Keating TA, Marshall CG, Walsh CT, Keating AE (2002) The structure of VibH represents nonribosomal peptide synthetase
condensation, cyclization and epimerization domains. None. [IF=None, Cited=129, 12055621].
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Natural Product Reports. [IF=3.292, Cited=97, 10331285].
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Communications. [IF=0.902, Cited=46, 12613585].
- Tello M, Jakimowicz P, Errey JC, ..., Field RA (2006) Characterisation of Streptomyces spheroides NovW and revision of
its functional assignment to a dTDP-6-deoxy-D-xylo-4-hexulose 3-epimerase. Chemical Communications. [IF=0.902,
Cited=13, 16514445].
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biosynthesis of chloramphenicol. Organic and Biomolecular Chemistry. [IF=0.77, Cited=16, 17520135].
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peptide pathways. Natural Product Reports. [IF=3.292, Cited=101, 18663394].
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Reports. [IF=3.292, Cited=100, 19636447].
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peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. [IF=3.292,
Cited=955, 23165928].
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and antibiotic resistance. Natural Product Reports. [IF=3.292, Cited=136, 1436736].
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its autoinhibitory domain. Biochemical Journal. [IF=0.852, Cited=28, 9003375].
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demonstrates a carboxyl terminus-mediated interaction with vitamin K hydroquinone. Journal of Biological Chemistry.
[IF=1.122, Cited=9, 7890642].
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Purification, cloning, overproduction, and characterization of a bifunctional glutathionylspermidine synthetase/amidase.
Journal of Biological Chemistry. [IF=1.122, Cited=50, 7775463].
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protein and role of the metal centers in transcription. Journal of Biological Chemistry. [IF=1.122, Cited=100, 7673113].
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Journal of Biological Chemistry. [IF=1.122, Cited=25, 7673185].
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regulator PhoB. Characterization and identification of a VanS domain that inhibits activation of PhoB. Journal of
Biological Chemistry. [IF=1.122, Cited=53, 7559459].
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protein synthase. Journal of Biological Chemistry. [IF=1.122, Cited=112, 7559576].
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occupancy of both SH2 domains. Journal of Biological Chemistry. [IF=1.122, Cited=145, 7531695].
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vitamin K-dependent carboxylase identified by site-directed mutagenesis. Journal of Biological Chemistry. [IF=1.122,
Cited=16, 8663364].
- Park IS, Walsh CT (1997) D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from
vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation. Journal of
Biological Chemistry. [IF=1.122, Cited=32, 9083053].
- Kwon DS, Lin CH, Chen S, ..., Bollinger JM (1997) Dissection of glutathionylspermidine synthetase/amidase from
Escherichia coli into autonomously folding and functional synthetase and amidase domains. Journal of Biological
Chemistry. [IF=1.122, Cited=22, 8999955].
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trypanothione biosynthesis in Crithidia fasciculata. Journal of Biological Chemistry. [IF=1.122, Cited=28, 9677355].
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transfer in Escherichia coli. Journal of Biological Chemistry. [IF=1.122, Cited=77, 10625633].
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glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. Journal of Biological Chemistry.
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lipoprotein transporter proteins. Journal of Biological Chemistry. [IF=1.122, Cited=25, 18171675].
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Nutrition. [IF=2.07, Cited=16, 7879739].
- Yasui A, Takao M, Oikawa A, ..., Eker AP (1988) Cloning and characterization of a photolyase gene from the
cyanobacterium Anacystis nidulans. Nucleic Acids Research. [IF=4.663, Cited=23, 2837735].
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O-methyltransferase NovP from the novobiocin-biosynthetic cluster of Streptomyces spheroides. None. [IF=None, Cited=2, 17329822].
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O-carbamoyltransferase NovN from the novobiocin-biosynthetic cluster of Streptomyces spheroides. None. [IF=None,
Cited=3, 18997325].
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studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-
L-epivancosamine biosynthetic pathway. None. [IF=None, Cited=4, 12077451].
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putative dTDP sugar epimerase NovW from the novobiocin biosynthetic cluster of Streptomyces spheroides. None. [IF=None,
Cited=3, 12876368].
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stimulates fetal globin gene expression in vitro and in vivo. British Journal of Haematology. [IF=1.359, Cited=31, 7529533].
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and mechanistic studies of the cloned enzyme over-produced in Escherichia coli. None. [IF=None, Cited=21, 3286259].
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communities. FEMS Microbiology Ecology. [IF=0.965, Cited=27, 21501195].
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Academy of Sciences. [IF=1.878, Cited=8, 4604751].
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and function. Journal of Bacteriology. [IF=0.898, Cited=50, 6298185].
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of phosphonic and phosphinic acid metabolism. Journal of Bacteriology. [IF=0.898, Cited=75, 3804975].
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methyl reductase and F420-reducing hydrogenase. Journal of Bacteriology. [IF=0.898, Cited=24, 3804976].
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phosphorus lyase activity of Escherichia coli K-12. Journal of Bacteriology. [IF=0.898, Cited=35, 3549702].
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Biochemistry. [IF=5.273, Cited=110, 6433782].
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acylation on dimeric VibF with mass spectrometry. Biophysical Journal. [IF=0.842, Cited=3, 16815901].