Tsai, Francis TF

Publication with MATCHING institution:

Mercado JM, Lee S, Chang C, ..., Tsai FT (2022) Atomic structure of the Leishmania spp. Hsp100 N-domain. Proteins:
Structure, Function and Bioinformatics. [IF=0.897, Cited=1, 35122310].
van Oosten-Hawle P, Backe SJ, Ben-Zvi A, ..., Truman AW (2023) Second Virtual International Symposium on Cellular and
Organismal Stress Responses, September 8-9, 2022. Cell Stress and Chaperones. [IF=0.931, Cited=0, 36602710].
Lee S, Roh SH, Lee J, ..., Tsai FT (2019) Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP
Conformation. Cell Reports. [IF=1.738, Cited=23, 30605683].
Teh-Poot CF, Dzul-Huchim VM, Mercado JM, ..., Cruz-Chan JV (2023) A short-term method to evaluate anti-leishmania drugs
by inhibition of stage differentiation in Leishmania mexicana using flow cytometry. Experimental Parasitology. [IF=0.72,
Cited=0, 37004860].
Eisa NH, Crowley VM, Elahi A, ..., Chadli A (2023) Enniatin A inhibits the chaperone Hsp90 and unleashes the immune
system against triple-negative breast cancer. iScience. [IF=1.12, Cited=3, 38025772].
Tsai JT, Sung N, Lee J, ..., Tsai FT (2019) Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding
Protein. Journal of Molecular Biology. [IF=1.281, Cited=1, 31202886].
Rizzolo K, Yu AYH, Ologbenla A, ..., Houry WA (2021) Functional cooperativity between the trigger factor chaperone and
the ClpXP proteolytic complex. Nature Communications. [IF=3.268, Cited=11, 33436616].
Rizzolo K, Yu AYH, Ologbenla A, ..., Houry WA (2021) Author Correction: Functional cooperativity between the trigger
factor chaperone and the ClpXP proteolytic complex. Nature Communications. [IF=3.268, Cited=0, 33958595].
Lee S, Lee SB, Sung N, ..., Tsai FT (2023) Structural basis of impaired disaggregase function in the oxidation-sensitive
SKD3 mutant causing 3-methylglutaconic aciduria. Nature Communications. [IF=3.268, Cited=1, 37041140].
Maneix L, Iakova P, Lee CG, ..., Catic A (2024) Cyclophilin A supports translation of intrinsically disordered proteins
and affects haematopoietic stem cell ageing. Nature Cell Biology. [IF=3.908, Cited=0, 38553595].
Mok SA, Condello C, Freilich R, ..., Gestwicki JE (2018) Mapping interactions with the chaperone network reveals factors
that protect against tau aggregation. Nature Structural and Molecular Biology. [IF=2.542, Cited=78, 29728653].
Lee J, Sung N, Mercado JM, ..., Tsai FT (2017) Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role
in Protein Disaggregation. Scientific Reports. [IF=1.312, Cited=11, 28894176].
Lee J, Sung N, Yeo L, ..., Tsai FT (2017) Structural determinants for protein unfolding and translocation by the Hsp104
protein disaggregase. Bioscience Reports. [IF=0.84, Cited=9, 29175998].
Lee G, Kim RS, Lee SB, ..., Tsai FT (2022) Deciphering the mechanism and function of Hsp100 unfoldases from protein
structure. Biochemical Society Transactions. [IF=0.925, Cited=1, 36454589].
Zhang J, Simisky J, Tsai FT, Geller DS (2005) A critical role of helix 3-helix 5 interaction in steroid hormone receptor
function. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=26, 15710879].
Lee S, Sielaff B, Lee J, Tsai FT (2010) CryoEM structure of Hsp104 and its mechanistic implication for protein
disaggregation. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=69, 20404203].
Biter AB, Lee S, Sung N, Tsai FT (2012) Structural basis for intersubunit signaling in a protein disaggregating machine.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=33, 22802670].
Lee J, Kim JH, Biter AB, ..., Tsai FT (2013) Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=75, 23650362].
Sung N, Lee J, Kim JH, ..., Tsai FT (2016) Mitochondrial Hsp90 is a ligand-activated molecular chaperone coupling ATP
binding to dimer closure through a coiled-coil intermediate. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=27, 26929380].
Zhang H, Murphy P, Yu J, ..., Ling J (2023) Coordination between aminoacylation and editing to protect against
proteotoxicity. Nucleic Acids Research. [IF=4.663, Cited=0, 37742077].
Sung N, Lee J, Kim JH, ..., Lee S (2016) 2.4 Å resolution crystal structure of human TRAP1NM, the Hsp90 paralog in the
mitochondrial matrix. Acta Crystallographica Section D: Structural Biology. [IF=1.47, Cited=9, 27487821].
Joshi A, Dai L, Liu Y, ..., Picard D (2020) The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and
is involved in mitochondrial metabolic homeostasis. BMC Biology. [IF=1.461, Cited=40, 31987035].
Jeng W, Lee S, Sung N, ..., Tsai FT (2015) Molecular chaperones: guardians of the proteome in normal and disease states.
F1000Research. [IF=0.912, Cited=19, 26918154].
Chang CW, Lee S, Tsai FT (2017) Structural Elements Regulating AAA+ Protein Quality Control Machines. Frontiers in
Molecular Biosciences. [IF=0.92, Cited=8, 28523272].
Maneix L, Sweeney MA, Lee S, ..., Catic A (2021) The Mitochondrial Protease LonP1 Promotes Proteasome Inhibitor
Resistance in Multiple Myeloma. Cancers. [IF=1.086, Cited=7, 33671345].
Tsai FT, Hill CP (2020) Same structure, different mechanisms? eLife. [IF=1.743, Cited=8, 32321627].

Publication with MISMATCHING institution:

Tsai FT, Sigler PB (2000) Structural basis of preinitiation complex assembly on human pol II promoters. EMBO Journal.
[IF=2.114, Cited=114, 10619841].
Tsai FT, Littlefield O, Kosa PF, ..., Sigler PB (1998) Polarity of transcription on Pol II and archaeal promoters: where
is the "one-way sign" and how is it read? Cold Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=3, 10384270].
Tsai FT, Subramanya HS, Brannigan JA, ..., Wigley DB (1996) Crystallization and preliminary crystallographic analysis of
the DNA gyrase B protein from B. stearothermophilus. None. [IF=None, Cited=1, 15299591].
Geller DS, Farhi A, Pinkerton N, ..., Lifton R (2000) Activating mineralocorticoid receptor mutation in hypertension
exacerbated by pregnancy. Science. [IF=7.729, Cited=286, 10884226].
Tsai FT, Singh OM, Skarzynski T, ..., Wigley DB (1997) The high-resolution crystal structure of a 24-kDa gyrase B
fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin. Proteins: Structure,
Function and Bioinformatics. [IF=0.897, Cited=0, 9144789].

Publication with MISSING institution:

Lewis RJ, Tsai FT, Wigley DB (1996) Molecular mechanisms of drug inhibition of DNA gyrase. BioEssays. [IF=0.818,
Cited=44, 8760340].
Rees I, Lee S, Kim H, Tsai FT (2006) The E3 ubiquitin ligase CHIP binds the androgen receptor in a phosphorylation-
dependent manner. None. [IF=None, Cited=40, 16725394].
Weibezahn J, Tessarz P, Schlieker C, ..., Bukau B (2004) Thermotolerance requires refolding of aggregated proteins by
substrate translocation through the central pore of ClpB. Cell. [IF=8.479, Cited=326, 15550247].
Sielaff B, Tsai FT (2010) The M-domain controls Hsp104 protein remodeling activity in an Hsp70/Hsp40-dependent manner.
Journal of Molecular Biology. [IF=1.281, Cited=72, 20654624].
Sielaff B, Lee KS, Tsai FT (2010) Structural and functional conservation of Mycobacterium tuberculosis GroEL paralogs
suggests that GroEL1 Is a chaperonin. Journal of Molecular Biology. [IF=1.281, Cited=12, 21094166].
Lee S, Sowa ME, Choi JM, Tsai FT (2004) The ClpB/Hsp104 molecular chaperone-a protein disaggregating machine. Journal of
Structural Biology. [IF=0.773, Cited=60, 15037241].
Biter AB, Lee J, Sung N, ..., Lee S (2012) Functional analysis of conserved cis- and trans-elements in the Hsp104
protein disaggregating machine. Journal of Structural Biology. [IF=0.773, Cited=18, 22634726].
Haslberger T, Weibezahn J, Zahn R, ..., Mogk A (2007) M domains couple the ClpB threading motor with the DnaK chaperone
activity. Molecular Cell. [IF=2.773, Cited=114, 17244532].
Lee S, Choi JM, Tsai FT (2007) Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for
substrate binding by ClpB. Molecular Cell. [IF=2.773, Cited=91, 17244533].
Augustin S, Gerdes F, Lee S, ..., Tatsuta T (2009) An intersubunit signaling network coordinates ATP hydrolysis by m-AAA
proteases. Molecular Cell. [IF=2.773, Cited=72, 19748354].
Perng CK, Ku HH, Chiou SH, ..., Kao CL (2006) Evaluation of wound healing effect on skin-defect nude mice by using human
dermis-derived mesenchymal stem cells. Transplantation Proceedings. [IF=0.445, Cited=12, 17112905].
Kao CL, Lin HT, Chen YW, ..., Ku HH (2007) Fibronectin suppresses lipopolysaccharide-induced liver damage and promotes
the cytoprotection abilities of hepatocyte-like cells derived from human bone marrow mesenchymal stem cells.
Transplantation Proceedings. [IF=0.445, Cited=6, 18089402].
Lee S, Sowa ME, Watanabe Yh, ..., Tsai FT (2003) The structure of ClpB: a molecular chaperone that rescues proteins from
an aggregated state. Cell. [IF=8.479, Cited=292, 14567920].
Lee S, Augustin S, Tatsuta T, ..., Tsai FT (2010) Electron cryomicroscopy structure of a membrane-anchored mitochondrial
AAA protease. Journal of Biological Chemistry. [IF=1.122, Cited=36, 21147776].
Saliba J, Zabriskie R, Ghosh R, ..., Plon SE (2016) Pharmacogenetic characterization of naturally occurring germline
NT5C1A variants to chemotherapeutic nucleoside analogs. Pharmacogenetics and Genomics. [IF=0.611, Cited=1, 26906009].
Lee S, Tsai FT (2007) Crystallization and preliminary X-ray crystallographic analysis of a 40 kDa N-terminal fragment of
the yeast prion-remodeling factor Hsp104. None. [IF=None, Cited=1, 17768355].
Sielaff B, Lee KS, Tsai FT (2010) Crystallization and preliminary X-ray crystallographic analysis of a GroEL1 fragment
from Mycobacterium tuberculosis H37Rv. None. [IF=None, Cited=2, 20383012].
Lee S, Hisayoshi M, Yoshida M, Tsai FT (2003) Crystallization and preliminary X-ray crystallographic analysis of the
Hsp100 chaperone ClpB from Thermus thermophilus. None. [IF=None, Cited=6, 14646112].
Zhang J, Tsai FT, Geller DS (2006) Differential interaction of RU486 with the progesterone and glucocorticoid receptors.
Journal of Molecular Endocrinology. [IF=0.999, Cited=11, 16901932].
Lee S, Tsai FT (2005) Molecular chaperones in protein quality control. None. [IF=None, Cited=31, 15943899].