Steitz, Thomas A

Publication with MATCHING institution:

Steitz TA (2010) From the structure and function of the ribosome to new antibiotics (Nobel Lecture). Angewandte Chemie -
International Edition. [IF=2.456, Cited=25, 20509130].
Joseph NN, Roy RN, Steitz TA (2020) Molecular dynamics analysis of Mg²⁺ -dependent cleavage of a pistol
ribozyme reveals a fail-safe secondary ion for catalysis. Journal of Computational Chemistry. [IF=1.045, Cited=3, 32091136].
Steitz TA, Rould MA, Perona JJ (1990) Structural basis of tRNA discrimination as derived from the high resolution
crystal structure of glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP. Molecular Biology Reports. [IF=0.735,
Cited=3, 2194108].
Steitz TA, Moore PB (2003) RNA, the first macromolecular catalyst: the ribosome is a ribozyme. Trends in Biochemical
Sciences. [IF=2.462, Cited=134, 12932729].
Lin J, Gagnon MG, Bulkley D, Steitz TA (2015) Conformational changes of elongation factor G on the ribosome during tRNA
translocation. Cell. [IF=8.479, Cited=81, 25594181].
Bulkley D, Brandi L, Polikanov YS, ..., Steitz TA (2014) The antibiotics dityromycin and GE82832 bind protein S12 and
block EF-G-catalyzed translocation. Cell Reports. [IF=1.738, Cited=26, 24412368].
Lomakin IB, Stolboushkina EA, Vaidya AT, ..., Steitz TA (2017) Crystal Structure of the Human Ribosome in Complex with
DENR-MCT-1. Cell Reports. [IF=1.738, Cited=35, 28723557].
Lomakin IB, De S, Wang J, ..., Steitz TA (2020) Crystal structure of the C-terminal domain of DENR. Computational and
Structural Biotechnology Journal. [IF=1.199, Cited=2, 32257053].
Steitz TA (2005) On the structural basis of peptide-bond formation and antibiotic resistance from atomic structures of
the large ribosomal subunit. FEBS Letters. [IF=0.871, Cited=19, 15680981].
Zuo Y, De S, Feng Y, Steitz TA (2020) Structural Insights into Transcription Initiation from De Novo RNA
Synthesis to Transitioning into Elongation. iScience. [IF=1.12, Cited=3, 32829286].
Vaidya AT, Lomakin IB, Joseph NN, ..., Steitz TA (2017) Crystal Structure of the C-terminal Domain of Human eIF2D and
Its Implications on Eukaryotic Translation Initiation. Journal of Molecular Biology. [IF=1.281, Cited=7, 28736176].
Polikanov YS, Osterman IA, Szal T, ..., Sergiev PV (2014) Amicoumacin a inhibits translation by stabilizing mRNA
interaction with the ribosome. Molecular Cell. [IF=2.773, Cited=48, 25306919].
Polikanov YS, Szal T, Jiang F, ..., Mankin AS (2014) Negamycin interferes with decoding and translocation by
simultaneous interaction with rRNA and tRNA. Molecular Cell. [IF=2.773, Cited=28, 25306922].
Zuo Y, Steitz TA (2015) Crystal structures of the E. coli transcription initiation complexes with a complete bubble.
Molecular Cell. [IF=2.773, Cited=152, 25866247].
Polikanov YS, Starosta AL, Juette MF, ..., Wilson DN (2015) Distinct tRNA Accommodation Intermediates Observed on the
Ribosome with the Antibiotics Hygromycin A and A201A. Molecular Cell. [IF=2.773, Cited=54, 26028538].
Steitz TA (2004) The structural basis of the transition from initiation to elongation phases of transcription, as well
as translocation and strand separation, by T7 RNA polymerase. Current Opinion in Structural Biology. [IF=1.4, Cited=35, 15102443].
Steitz TA (2009) The structural changes of T7 RNA polymerase from transcription initiation to elongation. Current
Opinion in Structural Biology. [IF=1.4, Cited=45, 19811903].
Ban N, Beckmann R, Cate JHD, ..., Yusupov M (2014) A new system for naming ribosomal proteins. Current Opinion in
Structural Biology. [IF=1.4, Cited=343, 24524803].
Steitz TA (2007) Collecting butterflies and the protein structure initiative: the right questions? Structure. [IF=1.155,
Cited=2, 18073100].
Steitz TA (1990) Structural studies of protein-nucleic acid interaction: the sources of sequence-specific binding.
Quarterly Reviews of Biophysics. [IF=1.372, Cited=272, 2204954].
Kang D, Zhang H, Wang Z, ..., Liu X (2019) Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1
Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical
Properties. Journal of Medicinal Chemistry. [IF=1.655, Cited=19, 30624934].
Li H, Cocco MJ, Steitz TA, Engelman DM (2001) Conversion of phospholamban into a soluble pentameric helical bundle.
Biochemistry. [IF=0.753, Cited=21, 11380258].
Wang M, Xia S, Blaha G, ..., Wang J (2010) Insights into base selectivity from the 1.8 Å resolution structure of an RB69
DNA polymerase ternary complex. Biochemistry. [IF=0.753, Cited=36, 21158418].
Wang J, Yu P, Lin TC, ..., Steitz TA (1996) Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its
complexes with single-stranded DNA and with divalent metal ions. Biochemistry. [IF=0.753, Cited=62, 8679562].
Arnez JG, Steitz TA (1996) Crystal structures of three misacylating mutants of Escherichia coli glutaminyl-tRNA
synthetase complexed with tRNA(Gln) and ATP. Biochemistry. [IF=0.753, Cited=24, 8942633].
Brautigam CA, Sun S, Piccirilli JA, Steitz TA (1999) Structures of normal single-stranded DNA and
deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia
coli. Biochemistry. [IF=0.753, Cited=48, 9888810].
Klosterman PS, Shah SA, Steitz TA (1999) Crystal structures of two plasmid copy control related RNA duplexes: An 18 base
pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution. Biochemistry. [IF=0.753, Cited=43, 10555960].
Ippolito JA, Kanyo ZF, Wang D, ..., Duffy EM (2008) Crystal structure of the oxazolidinone antibiotic linezolid bound to
the 50S ribosomal subunit. Journal of Medicinal Chemistry. [IF=1.655, Cited=140, 18494460].
Bunick CG, Presland RB, Lawrence OT, ..., Steitz TA (2015) Crystal Structure of Human Profilaggrin S100 Domain and
Identification of Target Proteins Annexin II, Stratifin, and HSP27. None. [IF=None, Cited=9, 25760235].
Steitz TA (2008) A structural understanding of the dynamic ribosome machine. Nature Reviews Molecular Cell Biology.
[IF=19.213, Cited=222, 18292779].
Brown JA, Bulkley D, Wang J, ..., Steitz JA (2014) Structural insights into the stabilization of MALAT1 noncoding RNA by
a bipartite triple helix. Nature Structural and Molecular Biology. [IF=2.542, Cited=146, 24952594].
Polikanov YS, Steitz TA, Innis CA (2014) A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation
on the ribosome. Nature Structural and Molecular Biology. [IF=2.542, Cited=126, 25132179].
Polikanov YS, Melnikov SV, Söll D, Steitz TA (2015) Structural insights into the role of rRNA modifications in protein
synthesis and ribosome assembly. Nature Structural and Molecular Biology. [IF=2.542, Cited=147, 25775268].
Roy RN, Lomakin IB, Gagnon MG, Steitz TA (2015) The mechanism of inhibition of protein synthesis by the proline-rich
peptide oncocin. Nature Structural and Molecular Biology. [IF=2.542, Cited=93, 25984972].
Steitz TA (2006) Visualizing polynucleotide polymerase machines at work. EMBO Journal. [IF=2.114, Cited=62, 16900098].
Pata JD, Stirtan WG, Goldstein SW, Steitz TA (2004) Structure of HIV-1 reverse transcriptase bound to an inhibitor
active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=38, 15249669].
Kamtekar S, Kennedy WD, Wang J, ..., Steitz TA (2003) The structural basis of cysteine aminoacylation of tRNAPro by
prolyl-tRNA synthetases. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=23, 12578991].
Rodríguez I, Lázaro JM, Blanco L, ..., de Vega M (2005) A specific subdomain in phi29 DNA polymerase confers both
processivity and strand-displacement capacity. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=56, 15845765].
Kamtekar S, Ho RS, Cocco MJ, ..., Steitz TA (2006) Implications of structures of synaptic tetramers of gamma delta
resolvase for the mechanism of recombination. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=32, 16807292].
Kamtekar S, Hohn MJ, Park HS, ..., Steitz TA (2007) Toward understanding phosphoseryl-tRNACys formation: the crystal
structure of Methanococcus maripaludis phosphoseryl-tRNA synthetase. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=23, 17301225].
Kavran JM, Gundllapalli S, O'Donoghue P, ..., Steitz TA (2007) Structure of pyrrolysyl-tRNA synthetase, an archaeal
enzyme for genetic code innovation. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=135, 17592110].
Simonović M, Steitz TA (2008) Cross-crystal averaging reveals that the structure of the peptidyl-transferase center is
the same in the 70S ribosome and the 50S subunit. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=13, 18187576].
Evans RN, Blaha G, Bailey S, Steitz TA (2008) The structure of LepA, the ribosomal back translocase. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=48, 18362332].
Nissen P, Ippolito JA, Ban N, ..., Steitz TA (2001) RNA tertiary interactions in the large ribosomal subunit: the
A-minor motif. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=421, 11296253].
Sharma H, Yu S, Kong J, ..., Steitz TA (2009) Structure of apo-CAP reveals that large conformational changes are
necessary for DNA binding. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=47, 19805344].
Bulkley D, Innis CA, Blaha G, Steitz TA (2010) Revisiting the structures of several antibiotics bound to the bacterial
ribosome. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=154, 20876130].
Eiler D, Lin J, Simonetti A, ..., Steitz TA (2013) Initiation factor 2 crystal structure reveals a different domain
organization from eukaryotic initiation factor 5B and mechanism among translational GTPases. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=22, 24029018].
Simonetti A, Marzi S, Billas IML, ..., Klaholz BP (2013) Involvement of protein IF2 N domain in ribosomal subunit
joining revealed from architecture and function of the full-length initiation factor. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=38, 24029017].
Eiler D, Wang J, Steitz TA (2014) Structural basis for the fast self-cleavage reaction catalyzed by the twister
ribozyme. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=45, 25157168].
Liu B, Zuo Y, Steitz TA (2015) Structural basis for transcription reactivation by RapA. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=40, 25646438].
Guo LT, Wang YS, Nakamura A, ..., Söll D (2014) Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=73, 25385624].
Liu B, Zuo Y, Steitz TA (2016) Structures of E. coli σS-transcription initiation complexes provide new insights into
polymerase mechanism. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=46, 27035955].
Gagnon MG, Lin J, Steitz TA (2016) Elongation factor 4 remodels the A-site tRNA on the ribosome. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=14, 27092003].
Nguyen LA, Wang J, Steitz TA (2017) Crystal structure of Pistol, a class of self-cleaving ribozyme. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=25, 28096403].
Hansen JL, Schmeing TM, Moore PB, Steitz TA (2002) Structural insights into peptide bond formation. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=140, 12185246].
Lomakin IB, Dmitriev SE, Steitz TA (2018) Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site
essential for heterodimer formation. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=13, 30584092].
Steitz TA, Richmond TJ, Wise D, Engelman D (1974) The lac repressor protein: molecular shape, subunit structure, and
proposed model for operator interaction based on structural studies of microcrystals. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=27, 4595565].
Freemont PS, Friedman JM, Beese LS, ..., Steitz TA (1988) Cocrystal structure of an editing complex of Klenow fragment
with DNA. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=150, 3194400].
DiGabriele AD, Sanderson MR, Steitz TA (1989) Crystal lattice packing is important in determining the bend of a DNA
dodecamer containing an adenine tract. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=136, 2928304].
Gartenberg MR, Ampe C, Steitz TA, Crothers DM (1990) Molecular characterization of the GCN4-DNA complex. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=52, 2201019].
Perona JJ, Rould MA, Steitz TA, ..., Brunie S (1991) Structural similarities in glutaminyl- and methionyl-tRNA
synthetases suggest a common overall orientation of tRNA binding. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=26, 2011598].
Kohlstaedt LA, Steitz TA (1992) Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or
Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=47, 1384059].
Kriwacki RW, Schultz SC, Steitz TA, Caradonna JP (1992) Sequence-specific recognition of DNA by zinc-finger peptides
derived from the transcription factor Sp1. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=78, 1329106].
Steitz TA, Steitz JA (1993) A general two-metal-ion mechanism for catalytic RNA. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=641, 8341661].
Wang J, Smerdon SJ, Jäger J, ..., Steitz TA (1994) Structural basis of asymmetry in the human immunodeficiency virus
type 1 reverse transcriptase heterodimer. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=107, 7518928].
Smerdon SJ, Jäger J, Wang J, ..., Steitz TA (1994) Structure of the binding site for nonnucleoside inhibitors of the
reverse transcriptase of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=164, 7513427].
Passner JM, Steitz TA (1997) The structure of a CAP-DNA complex having two cAMP molecules bound to each monomer.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=108, 9096308].
Ippolito JA, Steitz TA (1998) A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA
stem reveals a metal ion-dependent bulge conformation. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=97, 9707559].
Correll CC, Munishkin A, Chan YL, ..., Steitz TA (1998) Crystal structure of the ribosomal RNA domain essential for
binding elongation factors. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=116, 9811818].
Lu M, Steitz TA (2000) Structure of Escherichia coli ribosomal protein L25 complexed with a 5S rRNA fragment at 1.8-A
resolution. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=57, 10696113].
Steitz TA (1999) DNA polymerases: structural diversity and common mechanisms. Journal of Biological Chemistry.
[IF=1.122, Cited=437, 10364165].
Steitz TA, Weber IT, Ollis D, Brick P (1983) Crystallographic studies of protein-nucleic acid interaction: catabolite
gene activator protein and the large fragment of DNA polymerase I. Journal of Biomolecular Structure and Dynamics.
[IF=1.22, Cited=8, 6101086].
Zuo Y, Steitz TA (2016) A structure-based kinetic model of transcription. Transcription. [IF=1.038, Cited=6, 27656764].
Gagnon MG, Roy RN, Lomakin IB, ..., Steitz TA (2016) Structures of proline-rich peptides bound to the ribosome reveal a
common mechanism of protein synthesis inhibition. Nucleic Acids Research. [IF=4.663, Cited=86, 26809677].
Liu B, Steitz TA (2016) Structural insights into NusG regulating transcription elongation. Nucleic Acids Research.
[IF=4.663, Cited=26, 27899640].
Melnikov SV, Söll D, Steitz TA, Polikanov YS (2016) Insights into RNA binding by the anticancer drug cisplatin from the
crystal structure of cisplatin-modified ribosome. Nucleic Acids Research. [IF=4.663, Cited=32, 27079977].
Steitz TA, Yin YW (2004) Accuracy, lesion bypass, strand displacement and translocation by DNA polymerases.
Philosophical Transactions of the Royal Society B: Biological Sciences. [IF=1.629, Cited=24, 15065652].
Steitz TA, Moore PB (2017) Perspectives on the ribosome. Philosophical Transactions of the Royal Society B: Biological
Sciences. [IF=1.629, Cited=2, 28138074].
Steitz TA, Beese L, Freemont PS, ..., Sanderson MR (1987) Structural studies of Klenow fragment: an enzyme with two
active sites. Cold Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=17, 3331343].
Steitz TA, Smerdon S, Jäger J, ..., Rice PA (1993) Two DNA polymerases: HIV reverse transcriptase and the Klenow
fragment of Escherichia coli DNA polymerase I. Cold Spring Harbor Symposia on Quantitative Biology. [IF=0.889,
Cited=11, 7525146].
Ritacco CJ, Steitz TA, Wang J (2014) Exploiting large non-isomorphous differences for phase determination of a G-segment
invertase-DNA complex. None. [IF=None, Cited=1, 24598738].
Yin YW, Steitz TA (2002) Structural basis for the transition from initiation to elongation transcription in T7 RNA
polymerase. Science. [IF=7.729, Cited=211, 12242451].
Li W, Kamtekar S, Xiong Y, ..., Steitz TA (2005) Structure of a synaptic gammadelta resolvase tetramer covalently linked
to two cleaved DNAs. Science. [IF=7.729, Cited=78, 15994378].
Bailey S, Eliason WK, Steitz TA (2007) Structure of hexameric DnaB helicase and its complex with a domain of DnaG
primase. Science. [IF=7.729, Cited=141, 17947583].
Durniak KJ, Bailey S, Steitz TA (2008) The structure of a transcribing T7 RNA polymerase in transition from initiation
to elongation. Science. [IF=7.729, Cited=69, 18948533].
Steitz TA (2009) Retrospective. Frederic M. Richards (1925-2009). Science. [IF=7.729, Cited=0, 19251620].
Palioura S, Sherrer RL, Steitz TA, ..., Simonovic M (2009) The human SepSecS-tRNASec complex reveals the mechanism of
selenocysteine formation. Science. [IF=7.729, Cited=91, 19608919].
Blaha G, Stanley RE, Steitz TA (2009) Formation of the first peptide bond: the structure of EF-P bound to the 70S
ribosome. Science. [IF=7.729, Cited=135, 19696344].
Seidelt B, Innis CA, Wilson DN, ..., Beckmann R (2009) Structural insight into nascent polypeptide chain-mediated
translational stalling. Science. [IF=7.729, Cited=182, 19933110].
Pan B, Xiong Y, Steitz TA (2010) How the CCA-adding enzyme selects adenine over cytosine at position 76 of tRNA.
Science. [IF=7.729, Cited=26, 21071662].
Mitton-Fry RM, DeGregorio SJ, Wang J, ..., Steitz JA (2010) Poly(A) tail recognition by a viral RNA element through
assembly of a triple helix. Science. [IF=7.729, Cited=105, 21109672].
Gagnon MG, Seetharaman SV, Bulkley D, Steitz TA (2012) Structural basis for the rescue of stalled ribosomes: structure
of YaeJ bound to the ribosome. Science. [IF=7.729, Cited=74, 22422986].
Polikanov YS, Blaha GM, Steitz TA (2012) How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science.
[IF=7.729, Cited=128, 22605777].
Gagnon MG, Lin J, Bulkley D, Steitz TA (2014) Crystal structure of elongation factor 4 bound to a clockwise ratcheted
ribosome. Science. [IF=7.729, Cited=29, 25104389].
Kohlstaedt LA, Wang J, Friedman JM, ..., Steitz TA (1992) Crystal structure at 3.5 A resolution of HIV-1 reverse
transcriptase complexed with an inhibitor. Science. [IF=7.729, Cited=1000, 1377403].
Schultz SC, Shields GC, Steitz TA (1991) Crystal structure of a CAP-DNA complex: the DNA is bent by 90 degrees. Science.
[IF=7.729, Cited=682, 1653449].
Weeks KM, Ampe C, Schultz SC, ..., Crothers DM (1990) Fragments of the HIV-1 Tat protein specifically bind TAR RNA.
Science. [IF=7.729, Cited=280, 2205002].
Anderson CM, Zucker FH, Steitz TA (1979) Space-filling models of kinase clefts and conformation changes. Science.
[IF=7.729, Cited=117, 220706].
Rould MA, Perona JJ, Söll D, Steitz TA (1989) Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln)
and ATP at 2.8 A resolution. Science. [IF=7.729, Cited=513, 2479982].
Perona JJ, Swanson RN, Rould MA, ..., Söll D (1989) Structural basis for misaminoacylation by mutant E. coli glutaminyl-
tRNA synthetase enzymes. Science. [IF=7.729, Cited=39, 2686030].
Derbyshire V, Freemont PS, Sanderson MR, ..., Steitz TA (1988) Genetic and crystallographic studies of the
3',5'-exonucleolytic site of DNA polymerase I. Science. [IF=7.729, Cited=155, 2832946].
Cheetham GM, Steitz TA (1999) Structure of a transcribing T7 RNA polymerase initiation complex. Science. [IF=7.729,
Cited=204, 10600732].
Ban N, Nissen P, Hansen J, ..., Steitz TA (2000) The complete atomic structure of the large ribosomal subunit at 2.4 A
resolution. Science. [IF=7.729, Cited=1000, 10937989].
Nissen P, Hansen J, Ban N, ..., Steitz TA (2000) The structural basis of ribosome activity in peptide bond synthesis.
Science. [IF=7.729, Cited=1000, 10937990].
Bruist MF, Horvath SJ, Hood LE, ..., Simon MI (1987) Synthesis of a site-specific DNA-binding peptide. Science.
[IF=7.729, Cited=27, 3027895].
Steitz TA, Smerdon SJ, Jäger J, Joyce CM (1994) A unified polymerase mechanism for nonhomologous DNA and RNA
polymerases. Science. [IF=7.729, Cited=155, 7528445].
Story RM, Bishop DK, Kleckner N, Steitz TA (1993) Structural relationship of bacterial RecA proteins to recombination
proteins from bacteriophage T4 and yeast. Science. [IF=7.729, Cited=104, 8456313].
Beese LS, Derbyshire V, Steitz TA (1993) Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Science.
[IF=7.729, Cited=265, 8469987].
Liu B, Hong C, Huang RK, ..., Steitz TA (2017) Structural basis of bacterial transcription activation. Science.
[IF=7.729, Cited=45, 29146813].
Torabi SF, Vaidya AT, Tycowski KT, ..., Steitz JA (2021) RNA stabilization by a poly(A) tail 3'-end binding pocket and
other modes of poly(A)-RNA interaction. Science. [IF=7.729, Cited=19, 33414189].
Gürel G, Blaha G, Steitz TA, Moore PB (2009) Structures of triacetyloleandomycin and mycalamide A bind to the large
ribosomal subunit of Haloarcula marismortui. Antimicrobial Agents and Chemotherapy. [IF=1.175, Cited=31, 19738021].
Joyce CM, Steitz TA (1995) Polymerase structures and function: variations on a theme? Journal of Bacteriology.
[IF=0.898, Cited=104, 7592405].
Lin J, Zhou D, Steitz TA, ..., Gagnon MG (2018) Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of
Resistance, and Implications for Drug Design. Annual Review of Biochemistry. [IF=5.273, Cited=118, 29570352].
Joyce CM, Steitz TA (1994) Function and structure relationships in DNA polymerases. Annual Review of Biochemistry.
[IF=5.273, Cited=311, 7526780].
Moore PB, Steitz TA (2003) The structural basis of large ribosomal subunit function. Annual Review of Biochemistry.
[IF=5.273, Cited=80, 14527328].
Stabach PR, Simonović I, Ranieri MA, ..., Morrow JS (2009) The structure of the ankyrin-binding site of beta-spectrin
reveals how tandem spectrin-repeats generate unique ligand-binding properties. Blood. [IF=2.983, Cited=47, 19168783].
Yang Y, Kang D, Nguyen LA, ..., Steitz TA (2018) Structural basis for potent and broad inhibition of HIV-1 RT by
thiophene[3,2-d]pyrimidine non-nucleoside inhibitors. eLife. [IF=1.743, Cited=18, 30044217].
Steitz TA (None) DNA and RNA polymerases: structural diversity and common mechanisms. None. [IF=None, Cited=14, 10941420].

Publication with MISSING institution:

Steitz TA, Harrison R, Weber IT, Leahy M (1983) Ligand-induced conformational changes in proteins. None. [IF=None,
Cited=5, 6301781].
Beese LS, Steitz TA (1991) Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a
two metal ion mechanism. EMBO Journal. [IF=2.114, Cited=535, 1989886].
Hughes RE, Rice PA, Steitz TA, Grindley ND (1993) Protein-protein interactions directing resolvase site-specific
recombination: a structure-function analysis. EMBO Journal. [IF=2.114, Cited=35, 8385604].
Czworkowski J, Wang J, Steitz TA, Moore PB (1994) The crystal structure of elongation factor G complexed with GDP, at
2.7 A resolution. EMBO Journal. [IF=2.114, Cited=268, 8070396].
Freemont PS, Ollis DL, Steitz TA, Joyce CM (1986) A domain of the Klenow fragment of Escherichia coli DNA polymerase I
has polymerase but no exonuclease activity. Proteins: Structure, Function and Bioinformatics. [IF=0.897, Cited=43, 3329725].
Warwicker J, Engelman BP, Steitz TA (1987) Electrostatic calculations and model-building suggest that DNA bound to CAP
is sharply bent. Proteins: Structure, Function and Bioinformatics. [IF=0.897, Cited=49, 2834718].
Rice PA, Goldman A, Steitz TA (1990) A helix-turn-strand structural motif common in alpha-beta proteins. Proteins:
Structure, Function and Bioinformatics. [IF=0.897, Cited=19, 1708883].
DiGabriele AD, Steitz TA (1993) A DNA dodecamer containing an adenine tract crystallizes in a unique lattice and
exhibits a new bend. Journal of Molecular Biology. [IF=1.281, Cited=80, 8515463].
Jeruzalmi D, Steitz TA (1997) Use of organic cosmotropic solutes to crystallize flexible proteins: application to T7 RNA
polymerase and its complex with the inhibitor T7 lysozyme. Journal of Molecular Biology. [IF=1.281, Cited=10, 9405156].
Brautigam CA, Steitz TA (1998) Structural principles for the inhibition of the 3'-5' exonuclease activity of Escherichia
coli DNA polymerase I by phosphorothioates. Journal of Molecular Biology. [IF=1.281, Cited=103, 9514742].
Ippolito JA, Steitz TA (2000) The structure of the HIV-1 RRE high affinity rev binding site at 1.6 A resolution. Journal
of Molecular Biology. [IF=1.281, Cited=37, 10656783].
Li F, Wang J, Steitz TA (2000) Sulfolobus shibatae CCA-adding enzyme forms a tetramer upon binding two tRNA molecules: A
scrunching-shuttling model of CCA specificity. Journal of Molecular Biology. [IF=1.281, Cited=10, 11090289].
Passner JM, Schultz SC, Steitz TA (2000) Modeling the cAMP-induced allosteric transition using the crystal structure of
CAP-cAMP at 2.1 A resolution. Journal of Molecular Biology. [IF=1.281, Cited=130, 11124031].
Tu D, Blaha G, Moore PB, Steitz TA (2005) Gene replacement in Haloarcula marismortui: construction of a strain with two
of its three chromosomal rRNA operons deleted. Extremophiles. [IF=0.793, Cited=17, 15970993].
Steitz TA, Steitz TA, Henderson R, ..., Blow DM (1969) Structure of crystalline alpha-chymotrypsin. 3. Crystallographic
studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin. Journal of Molecular Biology.
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Steitz TA (1971) Structure of yeast hexokinase-B. I. Preliminary x-ray studies and subunit structure. Journal of
Molecular Biology. [IF=1.281, Cited=15, 5133118].
Steitz TA, Fletterick RJ, Hwang KJ (1973) Structure of yeast hexokinase. II. A 6 angstrom resolution electron density
map showing molecular shape and heterologous interaction of subunits. Journal of Molecular Biology. [IF=1.281,
Cited=28, 4585329].
Anderson WF, Fletterick RJ, Steitz TA (1974) Structure of yeast hexokinase. 3. Low resolution structure of a second
crystal form showing a different quaternary structure, heterologous interaction of subunits and substrate binding.
Journal of Molecular Biology. [IF=1.281, Cited=17, 4370398].
Anderson WF, Steitz TA (1975) Structure of yeast hexokinase. IV. Low-resoultion structure of enzyme-substrate complexes
revealing negative co-operativity and allosteric interactions. Journal of Molecular Biology. [IF=1.281, Cited=16, 1095755].
Steitz TA, Fletterick RJ, Anderson WF, Anderson CM (1976) High resolution x-ray structure of yeast hexokinase, an
allosteric protein exhibiting a non-symmetric arrangement of subunits. Journal of Molecular Biology. [IF=1.281,
Cited=59, 785010].
Richmond TJ, Steitz TA (1976) Protein-DNA interaction investigated by binding Escherichia coli lac repressor protein to
poly(d(A-U-HgX)). Journal of Molecular Biology. [IF=1.281, Cited=16, 785008].
Anderson CM, Stenkamp RE, McDonald RC, Steitz TA (1978) A refined model of the sugar binding site of yeast hexokinase B.
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Anderson CM, McDonald RC, Steitz TA (1978) Sequencing a protein by x-ray crystallography. I. Interpretation of yeast
hexokinase B at 2.5 A resolution by model building. Journal of Molecular Biology. [IF=1.281, Cited=31, 355642].
Anderson CM, Stenkamp RE, Steitz TA (1978) Sequencing a protein by x-ray crystallography. II. Refinement of yeast
hexokinase B co-ordinates and sequence at 2.1 A resolution. Journal of Molecular Biology. [IF=1.281, Cited=81, 355643].
Klug A, Jack A, Viswamitra MA, ..., Steitz TA (1979) A hypothesis on a specific sequence-dependent conformation of DNA
and its relation to the binding of the lac-repressor protein. Journal of Molecular Biology. [IF=1.281, Cited=205, 513130].
Bennett WS, Steitz TA (1980) Structure of a complex between yeast hexokinase A and glucose. I. Structure determination
and refinement at 3.5 A resolution. Journal of Molecular Biology. [IF=1.281, Cited=47, 7001031].
Bennett WS, Steitz TA (1980) Structure of a complex between yeast hexokinase A and glucose. II. Detailed comparisons of
conformation and active site configuration with the native hexokinase B monomer and dimer. Journal of Molecular Biology.
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Shoham M, Steitz TA (1980) Crystallographic studies and model building of ATP at the active site of hexokinase. Journal
of Molecular Biology. [IF=1.281, Cited=29, 7411639].
McKay DB, Pickover CA, Steitz TA (1982) Escherichia coli lac repressor is elongated with its operator DNA binding
domains located at both ends. Journal of Molecular Biology. [IF=1.281, Cited=25, 7047750].
Weber PC, Ollis DL, Bebrin WR, ..., Steitz TA (1982) Crystallization of resolvase, a repressor that also catalyzes site-
specific DNA recombination. Journal of Molecular Biology. [IF=1.281, Cited=6, 6288965].
Warwicker J, Ollis D, Richards FM, Steitz TA (1985) Electrostatic field of the large fragment of Escherichia coli DNA
polymerase I. Journal of Molecular Biology. [IF=1.281, Cited=39, 3912509].
Goldman A, Ollis D, Ngai KL, Steitz TA (1985) Crystal structure of muconate lactonizing enzyme at 6.5 A resolution.
Journal of Molecular Biology. [IF=1.281, Cited=8, 3999146].
Weber IT, Steitz TA (1986) Crystallization of recA protein from Proteus mirabilis. Journal of Molecular Biology.
[IF=1.281, Cited=0, 3519980].
Weber IT, Steitz TA (1987) Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A
resolution. Journal of Molecular Biology. [IF=1.281, Cited=292, 2828639].
Goldman A, Ollis DL, Steitz TA (1987) Crystal structure of muconate lactonizing enzyme at 3 A resolution. Journal of
Molecular Biology. [IF=1.281, Cited=38, 3612800].
Perona JJ, Swanson R, Steitz TA, Söll D (1988) Overproduction and purification of Escherichia coli tRNA(2Gln) and its
use in crystallization of the glutaminyl-tRNA synthetase-tRNA(Gln) complex. Journal of Molecular Biology. [IF=1.281,
Cited=39, 2459391].
Sanderson MR, Freemont PS, Murthy HM, ..., Steitz TA (1988) Purification and crystallization of thymidine kinase from
herpes simplex virus type 1. Journal of Molecular Biology. [IF=1.281, Cited=12, 2845104].
Hatfull GF, Sanderson MR, Freemont PS, ..., Steitz TA (1989) Preparation of heavy-atom derivatives using site-directed
mutagenesis. Introduction of cysteine residues into gamma delta resolvase. Journal of Molecular Biology. [IF=1.281,
Cited=29, 2553982].
Engelman DM, Steitz TA (1981) The spontaneous insertion of proteins into and across membranes: the helical hairpin
hypothesis. Cell. [IF=8.479, Cited=461, 7471207].
Sanderson MR, Freemont PS, Rice PA, ..., Steitz TA (1990) The crystal structure of the catalytic domain of the site-
specific recombination enzyme gamma delta resolvase at 2.7 A resolution. Cell. [IF=8.479, Cited=69, 2175678].
Hughes RE, Hatfull GF, Rice P, ..., Grindley ND (1990) Cooperativity mutants of the gamma delta resolvase identify an
essential interdimer interaction. Cell. [IF=8.479, Cited=56, 2175679].
Yang W, Steitz TA (1995) Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp
cleavage site. Cell. [IF=8.479, Cited=176, 7628011].
Shoham M, Steitz TA (1982) The 6-hydroxymethyl group of a hexose is essential for the substrate-induced closure of the
cleft in hexokinase. None. [IF=None, Cited=17, 6751401].
Landès C, Perona JJ, Brunie S, ..., Risler JL (1995) A structure-based multiple sequence alignment of all class I
aminoacyl-tRNA synthetases. Biochimie. [IF=0.926, Cited=32, 7647112].
Steitz TA, Goldman A, Engelman DM (1982) Quantitative application of the helical hairpin hypothesis to membrane
proteins. Biophysical Journal. [IF=0.842, Cited=15, 19431438].
Rife JP, Stallings SC, Correll CC, ..., Moore PB (1999) Comparison of the crystal and solution structures of two RNA
oligonucleotides. Biophysical Journal. [IF=0.842, Cited=18, 9876123].
Schultz SC, Shields GC, Steitz TA (1990) Crystallization of Escherichia coli catabolite gene activator protein with its
DNA binding site. The use of modular DNA. Journal of Molecular Biology. [IF=1.281, Cited=23, 2160019].
Simonović M, Steitz TA (2009) A structural view on the mechanism of the ribosome-catalyzed peptide bond formation. None.
[IF=None, Cited=42, 19595805].
Tu D, Blaha G, Moore PB, Steitz TA (2005) Structures of MLSBK antibiotics bound to mutated large ribosomal subunits
provide a structural explanation for resistance. Cell. [IF=8.479, Cited=270, 15851032].
Bailey S, Wing RA, Steitz TA (2006) The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic
replicative DNA polymerases. Cell. [IF=8.479, Cited=93, 16959569].
Lomakin IB, Xiong Y, Steitz TA (2007) The crystal structure of yeast fatty acid synthase, a cellular machine with eight
active sites working together. Cell. [IF=8.479, Cited=130, 17448991].
Itsathitphaisarn O, Wing RA, Eliason WK, ..., Steitz TA (2012) The hexameric helicase DnaB adopts a nonplanar
conformation during translocation. Cell. [IF=8.479, Cited=152, 23022319].
Klein DJ, Moore PB, Steitz TA (2004) The roles of ribosomal proteins in the structure assembly, and evolution of the
large ribosomal subunit. Journal of Molecular Biology. [IF=1.281, Cited=290, 15184028].
Voss NR, Gerstein M, Steitz TA, Moore PB (2006) The geometry of the ribosomal polypeptide exit tunnel. Journal of
Molecular Biology. [IF=1.281, Cited=191, 16784753].
Schroeder SJ, Blaha G, Tirado-Rives J, ..., Moore PB (2007) The structures of antibiotics bound to the E site region of
the 50 S ribosomal subunit of Haloarcula marismortui: 13-deoxytedanolide and girodazole. Journal of Molecular Biology.
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Kavran JM, Steitz TA (2007) Structure of the base of the L7/L12 stalk of the Haloarcula marismortui large ribosomal
subunit: analysis of L11 movements. Journal of Molecular Biology. [IF=1.281, Cited=36, 17599351].
Blaha G, Gürel G, Schroeder SJ, ..., Steitz TA (2008) Mutations outside the anisomycin-binding site can make ribosomes
drug-resistant. Journal of Molecular Biology. [IF=1.281, Cited=52, 18455733].
Wing RA, Bailey S, Steitz TA (2008) Insights into the replisome from the structure of a ternary complex of the DNA
polymerase III alpha-subunit. Journal of Molecular Biology. [IF=1.281, Cited=54, 18691598].
Gürel G, Blaha G, Moore PB, Steitz TA (2009) U2504 determines the species specificity of the A-site cleft antibiotics:
the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome. Journal of Molecular Biology.
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Bulkley D, Johnson F, Steitz TA (2012) The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit
bridge B2a of the ribosome. Journal of Molecular Biology. [IF=1.281, Cited=24, 22240456].
Kamtekar S, Berman AJ, Wang J, ..., Steitz TA (2004) Insights into strand displacement and processivity from the crystal
structure of the protein-primed DNA polymerase of bacteriophage phi29. Molecular Cell. [IF=2.773, Cited=94, 15546620].
Schmeing TM, Huang KS, Kitchen DE, ..., Steitz TA (2005) Structural insights into the roles of water and the 2' hydroxyl
of the P site tRNA in the peptidyl transferase reaction. Molecular Cell. [IF=2.773, Cited=152, 16285925].
Zuo Y, Wang Y, Steitz TA (2013) The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the
structure of their complex. Molecular Cell. [IF=2.773, Cited=125, 23623685].
Xiong Y, Steitz TA (2005) A story with a good ending: tRNA 3'-end maturation by CCA-adding enzymes. Current Opinion in
Structural Biology. [IF=1.4, Cited=54, 16364630].
Blaha GM, Polikanov YS, Steitz TA (2012) Elements of ribosomal drug resistance and specificity. Current Opinion in
Structural Biology. [IF=1.4, Cited=16, 22981944].
Liu B, Lin J, Steitz TA (2013) Structure of the PolIIIα-τc-DNA complex suggests an atomic model of the replisome.
Structure. [IF=1.155, Cited=10, 23478062].
Hansen JL, Moore PB, Steitz TA (2003) Structures of five antibiotics bound at the peptidyl transferase center of the
large ribosomal subunit. Journal of Molecular Biology. [IF=1.281, Cited=237, 12860128].
Brick P, Ollis D, Steitz TA (1983) Crystallization and 7 A resolution electron density map of the large fragment of
Escherichia coli DNA polymerase I. Journal of Molecular Biology. [IF=1.281, Cited=5, 6343618].
Ollis D, Brick P, Abdel-Meguid SS, ..., Steitz TA (1983) Crystals of Escherichia coli single-strand DNA-binding protein
show that the tetramer has D2 symmetry. Journal of Molecular Biology. [IF=1.281, Cited=18, 6355488].
Abdel-Meguid SS, Moore PB, Steitz TA (1983) Crystallization of a ribonuclease-resistant fragment of Escherichia coli 5 S
ribosomal RNA and its complex with protein L25. Journal of Molecular Biology. [IF=1.281, Cited=18, 6197527].
Wang J, Sattar AK, Wang CC, ..., Steitz TA (1997) Crystal structure of a pol alpha family replication DNA polymerase
from bacteriophage RB69. Cell. [IF=8.479, Cited=281, 9215631].
Correll CC, Freeborn B, Moore PB, Steitz TA (1997) Metals, motifs, and recognition in the crystal structure of a 5S rRNA
domain. Cell. [IF=8.479, Cited=238, 9393863].
Ban N, Freeborn B, Nissen P, ..., Steitz TA (1998) A 9 A resolution X-ray crystallographic map of the large ribosomal
subunit. Cell. [IF=8.479, Cited=130, 9657144].
Shamoo Y, Steitz TA (1999) Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA
polymerase and a polymerase editing complex. Cell. [IF=8.479, Cited=247, 10535734].
Franklin MC, Wang J, Steitz TA (2001) Structure of the replicating complex of a pol alpha family DNA polymerase. Cell.
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Li F, Xiong Y, Wang J, ..., Steitz TA (2002) Crystal structures of the Bacillus stearothermophilus CCA-adding enzyme and
its complexes with ATP or CTP. Cell. [IF=8.479, Cited=82, 12526808].
Yin YW, Steitz TA (2004) The structural mechanism of translocation and helicase activity in T7 RNA polymerase. Cell.
[IF=8.479, Cited=217, 15016374].
Brautigam CA, Steitz TA (1998) Structural and functional insights provided by crystal structures of DNA polymerases and
their substrate complexes. Current Opinion in Structural Biology. [IF=1.4, Cited=200, 9519297].
Cheetham GM, Steitz TA (2000) Insights into transcription: structure and function of single-subunit DNA-dependent RNA
polymerases. Current Opinion in Structural Biology. [IF=1.4, Cited=69, 10679468].
Rice PA, Steitz TA (1994) Refinement of gamma delta resolvase reveals a strikingly flexible molecule. Structure.
[IF=1.155, Cited=35, 8081753].
Yang W, Steitz TA (1995) Recombining the structures of HIV integrase, RuvC and RNase H. Structure. [IF=1.155,
Cited=144, 7735828].
Jäger J, Smerdon SJ, Wang J, ..., Steitz TA (1994) Comparison of three different crystal forms shows HIV-1 reverse
transcriptase displays an internal swivel motion. Structure. [IF=1.155, Cited=39, 7529124].
Rath VL, Silvian LF, Beijer B, ..., Steitz TA (1998) How glutaminyl-tRNA synthetase selects glutamine. Structure.
[IF=1.155, Cited=83, 9562563].
Brautigam CA, Aschheim K, Steitz TA (1999) Structural elucidation of the binding and inhibitory properties of lanthanide
(III) ions at the 3'-5' exonucleolytic active site of the Klenow fragment. None. [IF=None, Cited=19, 10631518].
Zhou BL, Pata JD, Steitz TA (2001) Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a
classic polymerase catalytic domain. Molecular Cell. [IF=2.773, Cited=121, 11545744].
Hansen JL, Ippolito JA, Ban N, ..., Steitz TA (2002) The structures of four macrolide antibiotics bound to the large
ribosomal subunit. Molecular Cell. [IF=2.773, Cited=306, 12150912].
Xiong Y, Li F, Wang J, ..., Steitz TA (2003) Crystal structures of an archaeal class I CCA-adding enzyme and its
nucleotide complexes. Molecular Cell. [IF=2.773, Cited=45, 14636575].
Perona JJ, Rould MA, Steitz TA (1993) Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-
tRNA synthetase. Biochemistry. [IF=0.753, Cited=117, 8364025].
Arnez JG, Steitz TA (1994) Crystal structure of unmodified tRNA(Gln) complexed with glutaminyl-tRNA synthetase and ATP
suggests a possible role for pseudo-uridines in stabilization of RNA structure. Biochemistry. [IF=0.753, Cited=151, 8011621].
Beese LS, Friedman JM, Steitz TA (1993) Crystal structures of the Klenow fragment of DNA polymerase I complexed with
deoxynucleoside triphosphate and pyrophosphate. Biochemistry. [IF=0.753, Cited=92, 8260491].
Weber IT, Steitz TA, Bubis J, Taylor SS (1987) Predicted structures of cAMP binding domains of type I and II regulatory
subunits of cAMP-dependent protein kinase. Biochemistry. [IF=0.753, Cited=60, 3030405].
McDonald RC, Steitz TA, Engelman DM (1979) Yeast hexokinase in solution exhibits a large conformational change upon
binding glucose or glucose 6-phosphate. Biochemistry. [IF=0.753, Cited=58, 369601].
Cheetham GM, Jeruzalmi D, Steitz TA (1999) Structural basis for initiation of transcription from an RNA polymerase-
promoter complex. Nature. [IF=11.591, Cited=173, 10331394].
Ban N, Nissen P, Hansen J, ..., Steitz TA (1999) Placement of protein and RNA structures into a 5 A-resolution map of
the 50S ribosomal subunit. Nature. [IF=11.591, Cited=201, 10476961].
McKay DB, Steitz TA (1981) Structure of catabolite gene activator protein at 2.9 A resolution suggests binding to left-
handed B-DNA. Nature. [IF=11.591, Cited=389, 6261152].
Ollis DL, Brick P, Hamlin R, ..., Steitz TA (None) Structure of large fragment of Escherichia coli DNA polymerase I
complexed with dTMP. Nature. [IF=11.591, Cited=475, 3883192].
Ollis DL, Kline C, Steitz TA (None) Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase.
Nature. [IF=11.591, Cited=59, 3883196].
Steitz TA (1998) A mechanism for all polymerases. Nature. [IF=11.591, Cited=344, 9440683].
Rould MA, Perona JJ, Steitz TA (1991) Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase.
Nature. [IF=11.591, Cited=214, 1857417].
Story RM, Weber IT, Steitz TA (1992) The structure of the E. coli recA protein monomer and polymer. Nature. [IF=11.591,
Cited=483, 1731246].
Story RM, Steitz TA (1992) Structure of the recA protein-ADP complex. Nature. [IF=11.591, Cited=383, 1731253].
Shamoo Y, Friedman AM, Parsons MR, ..., Steitz TA (1995) Crystal structure of a replication fork single-stranded DNA
binding protein (T4 gp32) complexed to DNA. Nature. [IF=11.591, Cited=173, 7630406].
Kim Y, Eom SH, Wang J, ..., Steitz TA (1995) Crystal structure of Thermus aquaticus DNA polymerase. Nature. [IF=11.591,
Cited=202, 7637814].
Eom SH, Wang J, Steitz TA (1996) Structure of Taq polymerase with DNA at the polymerase active site. Nature. [IF=11.591,
Cited=199, 8717047].
Moore PB, Steitz TA (2002) The involvement of RNA in ribosome function. Nature. [IF=11.591, Cited=93, 12110899].
Steitz TA (2011) Lunchtime science. Nature. [IF=11.591, Cited=1, 21993823].
Xiong Y, Steitz TA (2004) Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide
template. Nature. [IF=11.591, Cited=91, 15295590].
Schmeing TM, Huang KS, Strobel SA, Steitz TA (2005) An induced-fit mechanism to promote peptide bond formation and
exclude hydrolysis of peptidyl-tRNA. Nature. [IF=11.591, Cited=210, 16306996].
Lomakin IB, Steitz TA (2013) The initiation of mammalian protein synthesis and mRNA scanning mechanism. Nature.
[IF=11.591, Cited=121, 23873042].
Liu B, Eliason WK, Steitz TA (2013) Structure of a helicase-helicase loader complex reveals insights into the mechanism
of bacterial primosome assembly. Nature Communications. [IF=3.268, Cited=26, 24048025].
Shamoo Y, Krueger U, Rice LM, ..., Steitz TA (1997) Crystal structure of the two RNA binding domains of human hnRNP A1
at 1.75 A resolution. None. [IF=None, Cited=81, 9164463].
Bellon SF, Rodgers KK, Schatz DG, ..., Steitz TA (1997) Crystal structure of the RAG1 dimerization domain reveals
multiple zinc-binding motifs including a novel zinc binuclear cluster. None. [IF=None, Cited=79, 9228952].
Schmeing TM, Seila AC, Hansen JL, ..., Steitz TA (2002) A pre-translocational intermediate in protein synthesis observed
in crystals of enzymatically active 50S subunits. None. [IF=None, Cited=117, 11828326].
Yin FF, Bailey S, Innis CA, ..., Schatz DG (2009) Structure of the RAG1 nonamer binding domain with DNA reveals a dimer
that mediates DNA synapsis. Nature Structural and Molecular Biology. [IF=2.542, Cited=60, 19396172].
Stanley RE, Blaha G, Grodzicki RL, ..., Steitz TA (2010) The structures of the anti-tuberculosis antibiotics viomycin
and capreomycin bound to the 70S ribosome. Nature Structural and Molecular Biology. [IF=2.542, Cited=101, 20154709].
Kamtekar S, Berman AJ, Wang J, ..., Steitz TA (2006) The phi29 DNA polymerase:protein-primer structure suggests a model
for the initiation to elongation transition. EMBO Journal. [IF=2.114, Cited=64, 16511564].
Berman AJ, Kamtekar S, Goodman JL, ..., Steitz TA (2007) Structures of phi29 DNA polymerase complexed with substrate:
the mechanism of translocation in B-family polymerases. EMBO Journal. [IF=2.114, Cited=98, 17611604].
Steitz TA, Anderson C, Bennett W, ..., Stenkamp R (1977) Protomer structure of oligomeric enzymes: symmetry and
allosteric interactions in yeast hexokinase. Biochemical Society Transactions. [IF=0.925, Cited=3, 332556].
Steitz TA, Freemont PS, Ollis DL, ..., Grindley JM (1986) Functional implications of the Klenow fragment structure.
Biochemical Society Transactions. [IF=0.925, Cited=3, 3519313].
Steitz TA, Wiley DC, Lipscomb WN (1967) The structure of aspartate transcarbamylase, I. A molecular twofold axis in the
complex with cytidine triphosphate. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=4, 5237487].
Fletterick RJ, Bates DJ, Steitz TA (1975) The structure of a yeast hexokinase monomer and its complexes with substrates
at 2.7-A resolution. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=28, 164023].
Bennett WS, Steitz TA (1978) Glucose-induced conformational change in yeast hexokinase. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=138, 283394].
Steitz TA, Ohlendorf DH, McKay DB, ..., Matthews BW (1982) Structural similarity in the DNA-binding domains of
catabolite gene activator and cro repressor proteins. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=88, 6212926].
Weber IT, Takio K, Titani K, Steitz TA (1982) The cAMP-binding domains of the regulatory subunit of cAMP-dependent
protein kinase and the catabolite gene activator protein are homologous. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=49, 6296845].
Weber IT, Steitz TA (1984) Model of specific complex between catabolite gene activator protein and B-DNA suggested by
electrostatic complementarity. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=73, 6377305].
Abdel-Meguid SS, Grindley ND, Templeton NS, Steitz TA (1984) Cleavage of the site-specific recombination protein gamma
delta resolvase: the smaller of two fragments binds DNA specifically. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=51, 6326096].
Kaplan DL, Steitz TA (1999) DnaB from Thermus aquaticus unwinds forked duplex DNA with an asymmetric tail length
dependence. Journal of Biological Chemistry. [IF=1.122, Cited=24, 10066742].
Simonovic M, Zhang Z, Cianci CD, ..., Morrow JS (2006) Structure of the calmodulin alphaII-spectrin complex provides
insight into the regulation of cell plasticity. Journal of Biological Chemistry. [IF=1.122, Cited=27, 16945920].
Correll CC, Freeborn B, Moore PB, Steitz TA (1997) Use of chemically modified nucleotides to determine a 62-nucleotide
RNA crystal structure: a survey of phosphorothioates, Br, Pt and Hg. Journal of Biomolecular Structure and Dynamics.
[IF=1.22, Cited=14, 9399146].
Jeruzalmi D, Steitz TA (1998) Structure of T7 RNA polymerase complexed to the transcriptional inhibitor T7 lysozyme.
EMBO Journal. [IF=2.114, Cited=98, 9670025].
Jaeger J, Restle T, Steitz TA (1998) The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot
inhibitor. EMBO Journal. [IF=2.114, Cited=58, 9687519].
Klein DJ, Schmeing TM, Moore PB, Steitz TA (2001) The kink-turn: a new RNA secondary structure motif. EMBO Journal.
[IF=2.114, Cited=500, 11483524].
Weber IT, McKay DB, Steitz TA (1982) Two helix DNA binding motif of CAP found in lac repressor and gal repressor.
Nucleic Acids Research. [IF=4.663, Cited=72, 6897114].
Weber IT, Steitz TA (1984) A model for the non-specific binding of catabolite gene activator protein to DNA. Nucleic
Acids Research. [IF=4.663, Cited=14, 6390343].
Rice PA, Steitz TA (1989) Ribosomal protein L7/L12 has a helix-turn-helix motif similar to that found in DNA-binding
regulatory proteins. Nucleic Acids Research. [IF=4.663, Cited=15, 2660100].
Pata JD, King BR, Steitz TA (2002) Assembly, purification and crystallization of an active HIV-1 reverse transcriptase
initiation complex. Nucleic Acids Research. [IF=4.663, Cited=5, 12433988].
Bailey S, Eliason WK, Steitz TA (2007) The crystal structure of the Thermus aquaticus DnaB helicase monomer. Nucleic
Acids Research. [IF=4.663, Cited=33, 17606462].
Ritacco CJ, Kamtekar S, Wang J, Steitz TA (2012) Crystal structure of an intermediate of rotating dimers within the
synaptic tetramer of the G-segment invertase. Nucleic Acids Research. [IF=4.663, Cited=17, 23275567].
Mitra K, Steitz TA, Engelman DM (2002) Rational design of 'water-soluble' bacteriorhodopsin variants. None. [IF=None,
Cited=10, 12082167].
Birktoft JJ, Blow DM, Henderson R, ..., Steitz TA (1970) I. Serine proteinases. The structure of alpha-chymotrypsin.
Philosophical Transactions of the Royal Society B: Biological Sciences. [IF=1.629, Cited=41, 4399050].
Steitz TA, Shoham M, Bennett WS (1981) Structural dynamics of yeast hexokinase during catalysis. Philosophical
Transactions of the Royal Society B: Biological Sciences. [IF=1.629, Cited=35, 6115422].
Moore PB, Steitz TA (2011) The roles of RNA in the synthesis of protein. Cold Spring Harbor perspectives in biology.
[IF=1.926, Cited=37, 21068149].
Steitz TA, Weber IT, Matthew JB (1983) Catabolite gene activator protein: structure, homology with other proteins, and
cyclic AMP and DNA binding. Cold Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=19, 6305560].
Cheetham GM, Jeruzalmi D, Steitz TA (1998) Transcription regulation, initiation, and "DNA scrunching" by T7 RNA
polymerase. Cold Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=14, 10384290].
Hansen JL, Schmeing TM, Klein DJ, ..., Steitz TA (2001) Progress toward an understanding of the structure and enzymatic
mechanism of the large ribosomal subunit. Cold Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=6, 12762006].
Wang J, Kamtekar S, Berman AJ, Steitz TA (2004) Correction of X-ray intensities from single crystals containing lattice-
translocation defects. None. [IF=None, Cited=23, 15608377].
Eom SH, Song HK, Suh SW, ..., Lee DS (1995) Crystallization and preliminary X-ray crystallographic analysis of DNA
polymerase from Thermus aquaticus. None. [IF=None, Cited=1, 15299782].
Rould MA, Perona JJ, Steitz TA (1992) Improving multiple isomorphous replacement phasing by heavy-atom refinement using
solvent-flattened phases. None. [IF=None, Cited=15, 1445683].
Li F, Steitz TA (2003) A novel method of determining the number of macromolecules per asymmetric unit from accurate
crystal-volume measurements. None. [IF=None, Cited=1, 14501119].
Fresco JR, Hess GP, Russell RL, ..., Steitz TA (1970) Shapiro's defection. Science. [IF=7.729, Cited=0, 5416525].
Perros M, Steitz TA (1996) DNA looping and lac repressor-CAP interaction. Science. [IF=7.729, Cited=17, 8984647].
Gleick PH, Adams RM, Amasino RM, ..., Zoback ML (2010) Climate change and the integrity of science. Science. [IF=7.729,
Cited=12, 20448167].
Friedman AM, Fischmann TO, Steitz TA (1995) Crystal structure of lac repressor core tetramer and its implications for
DNA looping. Science. [IF=7.729, Cited=173, 7792597].
Steitz TA, Shulman RG (1982) Crystallographic and NMR studies of the serine proteases. None. [IF=None, Cited=79, 7049067].
Engelman DM, Steitz TA, Goldman A (1986) Identifying nonpolar transbilayer helices in amino acid sequences of membrane
proteins. None. [IF=None, Cited=683, 3521657].
Blow DM, Steitz TA (1970) X-ray diffraction studies of enzymes. Annual Review of Biochemistry. [IF=5.273, Cited=64, 5479039].
Simonović M, Steitz TA (2008) Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl
group of A76 of the unacylated A-site tRNA. RNA. [IF=0.956, Cited=16, 18818369].
Moore PB, Steitz TA (2003) After the ribosome structures: how does peptidyl transferase work? RNA. [IF=0.956, Cited=34, 12554855].
Schmeing TM, Moore PB, Steitz TA (2003) Structures of deacylated tRNA mimics bound to the E site of the large ribosomal
subunit. RNA. [IF=0.956, Cited=62, 14561884].
Klein DJ, Moore PB, Steitz TA (2004) The contribution of metal ions to the structural stability of the large ribosomal
subunit. RNA. [IF=0.956, Cited=172, 15317974].
Rice PA, Steitz TA (1994) Model for a DNA-mediated synaptic complex suggested by crystal packing of gamma delta
resolvase subunits. EMBO Journal. [IF=2.114, Cited=43, 8156989].
Silvian LF, Wang J, Steitz TA (1999) Insights into editing from an ile-tRNA synthetase structure with tRNAile and
mupirocin. Science. [IF=7.729, Cited=252, 10446055].
Polesky AH, Steitz TA, Grindley ND, Joyce CM (1990) Identification of residues critical for the polymerase activity of
the Klenow fragment of DNA polymerase I from Escherichia coli. Journal of Biological Chemistry. [IF=1.122, Cited=124, 2201688].
Abdel-Meguid SS, Murthy HM, Steitz TA (1986) Preliminary X-ray diffraction studies of the putative catalytic domain of
gamma delta resolvase from Escherichia coli. Journal of Biological Chemistry. [IF=1.122, Cited=5, 3023334].
Steitz TA, Anderson WF, Fletterick RJ, Anderson CM (1977) High resolution crystal structures of yeast hexokinase
complexes with substrates, activators, and inhibitors. Evidence for an allosteric control site. Journal of Biological
Chemistry. [IF=1.122, Cited=53, 326777].
McDonald RC, Engelman DM, Steitz TA (1979) Small angle X-ray scattering of dimeric yeast hexokinase in solution. Journal
of Biological Chemistry. [IF=1.122, Cited=8, 372185].
Pickover CA, McKay DB, Engelman DM, Steitz TA (1979) Substrate binding closes the cleft between the domains of yeast
phosphoglycerate kinase. Journal of Biological Chemistry. [IF=1.122, Cited=82, 387770].
Lipscomb WN, Hartsuck JA, Reeke GN, ..., Coppola JC (1968) The structure of carboxypeptidase A. VII. The 2.0-angstrom
resolution studies of the enzyme and of its complex with glycyltyrosine, and mechanistic deductions. None. [IF=None,
Cited=66, 5719196].
Steitz TA, Ludwig ML, Quiocho FA, Lipscomb WN (1967) The structure of carboxypepidase A. V. Studies of enzyme-substrate
and enzyme-inhibitor complexes at 6 A resolution. Journal of Biological Chemistry. [IF=1.122, Cited=26, 6061411].
McKay DB, Weber IT, Steitz TA (1982) Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation
of amino acid sequence and interactions with cyclic AMP. Journal of Biological Chemistry. [IF=1.122, Cited=110, 6286624].
McKay DB, Steitz TA, Weber IT, ..., Howard-Flanders P (1980) Crystallization of monomeric recA protein. Journal of
Biological Chemistry. [IF=1.122, Cited=20, 6446560].
Tormo J, Lamed R, Chirino AJ, ..., Steitz TA (1996) Crystal structure of a bacterial family-III cellulose-binding
domain: a general mechanism for attachment to cellulose. EMBO Journal. [IF=2.114, Cited=239, 8918451].

Steitz, Thomas A

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