Schultz, Peter G
Publication with MATCHING institution:
- Winssinger N, Harris JL, Backes BJ, Schultz PG (2001) From Split-Pool Libraries to Spatially Addressable Microarrays and
Its Application to Functional Proteomic Profiling. Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 29712061].
- Schultz PG, Yin J, Lerner RA (2002) The chemistry of the antibody molecule. Angewandte Chemie - International Edition.
[IF=2.456, Cited=28, 12458503].
- Kularatne SA, Deshmukh V, Gymnopoulos M, ..., Schultz PG (2013) Recruiting cytotoxic T cells to folate-receptor-positive
cancer cells. Angewandte Chemie - International Edition. [IF=2.456, Cited=16, 24573789].
- Cao Y, Axup JY, Ma JSY, ..., Kim CH (2015) Multiformat T-cell-engaging bispecific antibodies targeting human breast
cancers. Angewandte Chemie - International Edition. [IF=2.456, Cited=25, 25919418].
- Luo X, Liu T, Wang Y, ..., Wang F (2015) An Epitope-Specific Respiratory Syncytial Virus Vaccine Based on an Antibody
Scaffold. Angewandte Chemie - International Edition. [IF=2.456, Cited=8, 26434555].
- Cao Y, Rodgers DT, Du J, ..., Young TS (2016) Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast
Cancer. Angewandte Chemie - International Edition. [IF=2.456, Cited=56, 27145250].
- Xuan W, Li J, Luo X, Schultz PG (2016) Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins.
Angewandte Chemie - International Edition. [IF=2.456, Cited=26, 27418387].
- Xuan W, Shao S, Schultz PG (2017) Protein Crosslinking by Genetically Encoded Noncanonical Amino Acids with Reactive
Aryl Carbamate Side Chains. Angewandte Chemie - International Edition. [IF=2.456, Cited=31, 28371162].
- Xuan W, Schultz PG (2017) A Strategy for Creating Organisms Dependent on Noncanonical Amino Acids. Angewandte Chemie -
International Edition. [IF=2.456, Cited=10, 28593724].
- Kessel C, Nandakumar KS, Peters FB, ..., Holmdahl R (2014) A single functional group substitution in c5a breaks B cell
and T cell tolerance and protects against experimental arthritis. Arthritis and Rheumatology. [IF=3.262, Cited=11, 24574221].
- Kang M, Light K, Ai HW, ..., Schultz PG (2014) Evolution of iron(II)-finger peptides by using a bipyridyl amino acid.
ChemBioChem. [IF=0.691, Cited=22, 24591102].
- Lee TC, Kang M, Kim CH, ..., Deniz AA (2016) Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to
Enable Single-Molecule FRET Studies of p97 Folding. ChemBioChem. [IF=0.691, Cited=15, 27115850].
- Iaconelli J, Ibrahim L, Chen E, ..., Bollong MJ (2019) Small-Molecule Stimulators of NRF1 Transcriptional Activity.
ChemBioChem. [IF=0.691, Cited=6, 31596542].
- Jo J, Ibrahim L, Iaconelli J, ..., Yun H (2021) Discovery and SAR studies of
3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE)
activators. Bioorganic Chemistry. [IF=1.325, Cited=5, 33508678].
- Yao A, Reed SA, Koh M, ..., Schultz PG (2018) Progress toward a reduced phage genetic code. Bioorganic and Medicinal
Chemistry. [IF=0.86, Cited=1, 29609949].
- Zambaldo C, Koh M, Nasertorabi F, ..., Schultz PG (2020) An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical
amino acid mutagenesis in Escherichia coli. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=6, 33069069].
- Johnson SM, Sharif O, Mak PA, ..., Chapman E (2014) A biochemical screen for GroEL/GroES inhibitors. Bioorganic and
Medicinal Chemistry Letters. [IF=0.704, Cited=26, 24418775].
- Abdeen S, Salim N, Mammadova N, ..., Johnson SM (2016) GroEL/ES inhibitors as potential antibiotics. Bioorganic and
Medicinal Chemistry Letters. [IF=0.704, Cited=23, 27184767].
- Abdeen S, Salim N, Mammadova N, ..., Johnson SM (2016) Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei
as a strategy for treating African sleeping sickness. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=18, 27720295].
- Supekova L, Zambaldo C, Choi S, ..., Schultz PG (2018) The genetic incorporation of p-azidomethyl-l-phenylalanine into
proteins in yeast. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=0, 29625824].
- Crnovcic I, Gan F, Yang D, ..., Shen B (2018) Activities of recombinant human bleomycin hydrolase on bleomycins and
engineered analogues revealing new opportunities to overcome bleomycin-induced pulmonary toxicity. Bioorganic and
Medicinal Chemistry Letters. [IF=0.704, Cited=8, 29730026].
- Liu T, Du J, Luo X, ..., Wang F (2015) Homogeneously modified immunoglobulin domains for therapeutic application.
Current Opinion in Chemical Biology. [IF=1.51, Cited=8, 26117722].
- Shim HS, Iaconelli J, Shang X, ..., DePinho RA (2024) TERT activation targets DNA methylation and multiple aging
hallmarks. Cell. [IF=8.479, Cited=0, 38908367].
- Luo X, Wang TSA, Zhang Y, ..., Schultz PG (2016) Stabilizing Protein Motifs with a Genetically Encoded Metal-Ion
Chelator. Cell Chemical Biology. [IF=1.446, Cited=8, 27662253].
- Liu T, Jia P, Ma H, ..., Schultz PG (2017) Construction and Screening of a Lentiviral Secretome Library. Cell Chemical
Biology. [IF=1.446, Cited=8, 28602759].
- Martínez-Peña F, Pearson AD, Tang EL, ..., Lairson LL (2022) Synthesis and biological evaluation of novel FiVe1
derivatives as potent and selective agents for the treatment of mesenchymal cancers. European Journal of Medicinal
Chemistry. [IF=1.568, Cited=1, 36001933].
- Decker RS, Koyama E, Enomoto-Iwamoto M, ..., Pacifici M (2014) Mouse limb skeletal growth and synovial joint development
are coordinately enhanced by Kartogenin. Developmental Biology. [IF=0.815, Cited=37, 25238962].
- Yang PY, Zou H, Amso Z, ..., Shen W (2020) New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles
Exhibit Weight Reducing and Anti-Steatotic Properties in Mice. Bioconjugate Chemistry. [IF=0.921, Cited=8, 32243137].
- Lim RKV, Yu S, Cheng B, ..., Kazane SA (2015) Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug
Conjugate. Bioconjugate Chemistry. [IF=0.921, Cited=33, 25945727].
- Ahmed N, De Graaf JF, Ahmed N, ..., Pezacki JP (2018) Visualization of the Delivery and Release of Small RNAs Using
Genetic Code Expansion and Unnatural RNA-Binding Proteins. Bioconjugate Chemistry. [IF=0.921, Cited=2, 30408949].
- Koh M, Cho HY, Yu C, ..., Schultz PG (2019) Site-Specific Incorporation of a Dithiolane Containing Amino Acid into
Proteins. Bioconjugate Chemistry. [IF=0.921, Cited=2, 31319026].
- Lear S, Pflimlin E, Zhou Z, ..., Shen W (2020) Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a
GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity. Journal of Medicinal Chemistry. [IF=1.655, Cited=6, 32844654].
- Dayan Elshan NGR, Wolff KC, Riva L, ..., Schultz PG (2024) Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease
Inhibitor Bearing a Novel Warhead. Journal of Medicinal Chemistry. [IF=1.655, Cited=1, 38335279].
- Elshan NGRD, Wolff KC, Riva L, ..., Schultz PG (2024) Correction to "Discovery of CMX990: A Potent SARS-CoV-2 3CL
Protease Inhibitor Bearing a Novel Warhead". Journal of Medicinal Chemistry. [IF=1.655, Cited=0, 38875353].
- Yang PY, Zou H, Lee C, ..., Shen W (2018) Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran
Sodium Sulfate Induced Mouse Colitis Models. Journal of Medicinal Chemistry. [IF=1.655, Cited=18, 29528634].
- Abdeen S, Kunkle T, Salim N, ..., Johnson SM (2018) Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent
Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA). Journal of Medicinal Chemistry. [IF=1.655,
Cited=10, 30060666].
- Bollong MJ, Yun H, Sherwood L, ..., Schultz PG (2015) A Small Molecule Inhibits Deregulated NRF2 Transcriptional
Activity in Cancer. ACS Chemical Biology. [IF=0.963, Cited=50, 26270491].
- Muppidi A, Zou H, Yang PY, ..., Shen W (2016) Design of Potent and Proteolytically Stable Oxyntomodulin Analogs. ACS
Chemical Biology. [IF=0.963, Cited=16, 26727558].
- Liu Y, Wang Y, Zhang Y, ..., Wang F (2016) Rational Design of Dual Agonist-Antibody Fusions as Long-acting Therapeutic
Hormones. ACS Chemical Biology. [IF=0.963, Cited=0, 27704775].
- Choi SH, Mahankali M, Lee SJ, ..., Shen W (2017) Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule.
ACS Chemical Biology. [IF=0.963, Cited=31, 28976731].
- Young DD, Schultz PG (2018) Playing with the Molecules of Life. ACS Chemical Biology. [IF=0.963, Cited=153, 29345901].
- Xuan W, Collins D, Koh M, ..., Schultz PG (2018) Site-Specific Incorporation of a Thioester Containing Amino Acid into
Proteins. ACS Chemical Biology. [IF=0.963, Cited=8, 29360343].
- Li JC, Nastertorabi F, Xuan W, ..., Schultz PG (2019) A Single Reactive Noncanonical Amino Acid Is Able to Dramatically
Stabilize Protein Structure. ACS Chemical Biology. [IF=0.963, Cited=9, 31181898].
- Yin J, Mundorff EC, Yang PL, ..., Schultz PG (2001) A comparative analysis of the immunological evolution of antibody
28B4. Biochemistry. [IF=0.753, Cited=51, 11535051].
- Licht SS, Sonnleitner A, Weiss S, Schultz PG (2003) A rugged energy landscape mechanism for trapping of transmembrane
receptors during endocytosis. Biochemistry. [IF=0.753, Cited=14, 12627957].
- Zhang Z, Smith BAC, Wang L, ..., Schultz PG (2003) A new strategy for the site-specific modification of proteins in
vivo. Biochemistry. [IF=0.753, Cited=106, 12779328].
- Anderson JC, Schultz PG (2003) Adaptation of an orthogonal archaeal leucyl-tRNA and synthetase pair for four-base,
amber, and opal suppression. Biochemistry. [IF=0.753, Cited=64, 12911301].
- Mukherji M, Brill LM, Ficarro SB, ..., Schultz PG (2006) A phosphoproteomic analysis of the ErbB2 receptor tyrosine
kinase signaling pathways. Biochemistry. [IF=0.753, Cited=33, 17176074].
- Young DD, Young TS, Jahnz M, ..., Schultz PG (2011) An evolved aminoacyl-tRNA synthetase with atypical polysubstrate
specificity. Biochemistry. [IF=0.753, Cited=115, 21280675].
- Chatterjee A, Sun SB, Furman JL, ..., Schultz PG (2013) A versatile platform for single- and multiple-unnatural amino
acid mutagenesis in Escherichia coli. Biochemistry. [IF=0.753, Cited=167, 23379331].
- Young TS, Ahmad I, Brock A, Schultz PG (2009) Expanding the genetic repertoire of the methylotrophic yeast Pichia
pastoris. Biochemistry. [IF=0.753, Cited=34, 19265424].
- Liu CC, Choe H, Farzan M, ..., Schultz PG (2009) Mutagenesis and evolution of sulfated antibodies using an expanded
genetic code. Biochemistry. [IF=0.753, Cited=25, 19715291].
- Mundorff EC, Hanson MA, Varvak A, ..., Stevens RC (2000) Conformational effects in biological catalysis: an antibody-
catalyzed oxy-cope rearrangement. Biochemistry. [IF=0.753, Cited=23, 10651626].
- Dubrovska A, Kim C, Elliott J, ..., Schultz PG (2011) A chemically induced vaccine strategy for prostate cancer. ACS
Chemical Biology. [IF=0.963, Cited=20, 21936526].
- de Lichtervelde L, Boitano AE, Wang Y, ..., Schultz PG (2013) Eupalinilide E inhibits erythropoiesis and promotes the
expansion of hematopoietic progenitor cells. ACS Chemical Biology. [IF=0.963, Cited=3, 23441826].
- Niu W, Schultz PG, Guo J (2013) An expanded genetic code in mammalian cells with a functional quadruplet codon. ACS
Chemical Biology. [IF=0.963, Cited=59, 23662731].
- Swoboda JG, Elliott J, Deshmukh V, ..., Schultz PG (2013) Small molecule mediated proliferation of primary retinal
pigment epithelial cells. ACS Chemical Biology. [IF=0.963, Cited=5, 23621521].
- Zhang Y, Wang D, Welzel G, ..., Wang F (2013) An antibody CDR3-erythropoietin fusion protein. ACS Chemical Biology.
[IF=0.963, Cited=15, 23941200].
- Javahishvili T, Manibusan A, Srinagesh S, ..., Schultz PG (2014) Role of tRNA orthogonality in an expanded genetic code.
ACS Chemical Biology. [IF=0.963, Cited=6, 24443971].
- Rust HL, Subramanian V, West GM, ..., Thompson PR (2014) Using unnatural amino acid mutagenesis to probe the regulation
of PRMT1. ACS Chemical Biology. [IF=0.963, Cited=23, 24358983].
- Xiao H, Peters FB, Yang PY, ..., Schultz PG (2014) Genetic incorporation of histidine derivatives using an engineered
pyrrolysyl-tRNA synthetase. ACS Chemical Biology. [IF=0.963, Cited=41, 24506189].
- Xiao H, Xuan W, Shao S, ..., Schultz PG (2015) Genetic Incorporation of ε-N-2-Hydroxyisobutyryl-lysine into Recombinant
Histones. ACS Chemical Biology. [IF=0.963, Cited=29, 25909834].
- Hong J, Lee J, Min KH, ..., Schultz PG (2007) Identification and characterization of small-molecule inducers of
epidermal keratinocyte differentiation. ACS Chemical Biology. [IF=0.963, Cited=9, 17348628].
- Xie J, Supekova L, Schultz PG (2007) A genetically encoded metabolically stable analogue of phosphotyrosine in
Escherichia coli. ACS Chemical Biology. [IF=0.963, Cited=49, 17622177].
- Ding S, Gray NS, Ding Q, ..., Schultz PG (2002) Resin-capture and release strategy toward combinatorial libraries of
2,6,9-substituted purines. None. [IF=None, Cited=6, 11886295].
- Tae EL, Wu Y, Xia G, ..., Romesberg FE (2001) Efforts toward expansion of the genetic alphabet: replication of DNA with
three base pairs. Journal of the American Chemical Society. [IF=2.573, Cited=53, 11472182].
- Lin Q, Jiang F, Schultz PG, Gray NS (2001) Design of allele-specific protein methyltransferase inhibitors. Journal of
the American Chemical Society. [IF=2.573, Cited=48, 11716715].
- Atwell S, Meggers E, Spraggon G, Schultz PG (2001) Structure of a copper-mediated base pair in DNA. Journal of the
American Chemical Society. [IF=2.573, Cited=81, 11734038].
- Wang L, Brock A, Schultz PG (2002) Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli. Journal of the
American Chemical Society. [IF=2.573, Cited=56, 11866580].
- Ding S, Gray NS, Wu X, ..., Schultz PG (2002) A combinatorial scaffold approach toward kinase-directed heterocycle
libraries. Journal of the American Chemical Society. [IF=2.573, Cited=72, 11853431].
- Chang YT, Choi J, Ding S, ..., Schultz PG (2002) The synthesis and biological characterization of a ceramide library.
Journal of the American Chemical Society. [IF=2.573, Cited=27, 11866590].
- Chapman E, Ding S, Schultz PG, Wong CH (2002) A potent and highly selective sulfotransferase inhibitor. Journal of the
American Chemical Society. [IF=2.573, Cited=16, 12465948].
- Chin JW, Santoro SW, Martin AB, ..., Schultz PG (2002) Addition of p-azido-L-phenylalanine to the genetic code of
Escherichia coli. Journal of the American Chemical Society. [IF=2.573, Cited=391, 12148987].
- Zimmermann N, Meggers E, Schultz PG (2002) A novel silver(i)-mediated DNA base pair. Journal of the American Chemical
Society. [IF=2.573, Cited=62, 12431092].
- Wu Y, Fa M, Tae EL, ..., Romesberg FE (2002) Enzymatic phosphorylation of unnatural nucleosides. Journal of the American
Chemical Society. [IF=2.573, Cited=20, 12465973].
- Wu X, Ding S, Ding Q, ..., Schultz PG (2002) A small molecule with osteogenesis-inducing activity in multipotent
mesenchymal progenitor cells. Journal of the American Chemical Society. [IF=2.573, Cited=113, 12465946].
- Lin Q, Barbas CF, Schultz PG (2003) Small-molecule switches for zinc finger transcription factors. Journal of the
American Chemical Society. [IF=2.573, Cited=21, 12526643].
- Mehl RA, Anderson JC, Santoro SW, ..., Schultz PG (2003) Generation of a bacterium with a 21 amino acid genetic code.
Journal of the American Chemical Society. [IF=2.573, Cited=125, 12537491].
- Liu H, Wang L, Brock A, ..., Schultz PG (2003) A method for the generation of glycoprotein mimetics. Journal of the
American Chemical Society. [IF=2.573, Cited=55, 12580587].
- Matsuda S, Henry AA, Schultz PG, Romesberg FE (2003) The effect of minor-groove hydrogen-bond acceptors and donors on
the stability and replication of four unnatural base pairs. Journal of the American Chemical Society. [IF=2.573,
Cited=27, 12785844].
- Deiters A, Cropp TA, Mukherji M, ..., Schultz PG (2003) Adding amino acids with novel reactivity to the genetic code of
Saccharomyces cerevisiae. Journal of the American Chemical Society. [IF=2.573, Cited=161, 14505376].
- Chen S, Zhang Q, Wu X, ..., Ding S (2004) Dedifferentiation of lineage-committed cells by a small molecule. Journal of
the American Chemical Society. [IF=2.573, Cited=155, 14719906].
- Alfonta L, Zhang Z, Uryu S, ..., Schultz PG (2003) Site-specific incorporation of a redox-active amino acid into
proteins. Journal of the American Chemical Society. [IF=2.573, Cited=63, 14640614].
- Wu X, Ding S, Ding Q, ..., Schultz PG (2004) Small molecules that induce cardiomyogenesis in embryonic stem cells.
Journal of the American Chemical Society. [IF=2.573, Cited=123, 14871063].
- Yin J, Mills JH, Schultz PG (2004) A catalysis-based selection for peroxidase antibodies with increased activity.
Journal of the American Chemical Society. [IF=2.573, Cited=12, 15012103].
- Wu N, Deiters A, Cropp TA, ..., Schultz PG (2004) A genetically encoded photocaged amino acid. Journal of the American
Chemical Society. [IF=2.573, Cited=154, 15521721].
- Xu R, Hanson SR, Zhang Z, ..., Wong CH (2004) Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-
O-threonine into protein in Escherichia coli. Journal of the American Chemical Society. [IF=2.573, Cited=30, 15571382].
- Tian F, Tsao ML, Schultz PG (2004) A phage display system with unnatural amino acids. Journal of the American Chemical
Society. [IF=2.573, Cited=78, 15584720].
- Venkateshrao S, Yin J, Jarzecki AA, ..., Spiro TG (2004) Porphyrin distortion during affinity maturation of a
ferrochelatase antibody, monitored by Resonance Raman spectroscopy. Journal of the American Chemical Society. [IF=2.573,
Cited=18, 15600337].
- Spence MM, Ruiz EJ, Rubin SM, ..., Pines A (2004) Development of a functionalized xenon biosensor. Journal of the
American Chemical Society. [IF=2.573, Cited=49, 15548026].
- Turner JM, Graziano J, Spraggon G, Schultz PG (2005) Structural characterization of a p-acetylphenylalanyl aminoacyl-
tRNA synthetase. Journal of the American Chemical Society. [IF=2.573, Cited=24, 16248607].
- Bose M, Groff D, Xie J, ..., Schultz PG (2006) The incorporation of a photoisomerizable amino acid into proteins in E.
coli. Journal of the American Chemical Society. [IF=2.573, Cited=78, 16402807].
- Tsao ML, Summerer D, Ryu Y, Schultz PG (2006) The genetic incorporation of a distance probe into proteins in Escherichia
coli. Journal of the American Chemical Society. [IF=2.573, Cited=28, 16594684].
- Wang J, Xie J, Schultz PG (2006) A genetically encoded fluorescent amino acid. Journal of the American Chemical Society.
[IF=2.573, Cited=143, 16819861].
- Schultz KC, Supekova L, Ryu Y, ..., Schultz PG (2006) A genetically encoded infrared probe. Journal of the American
Chemical Society. [IF=2.573, Cited=127, 17061854].
- Matsuda S, Fillo JD, Henry AA, ..., Romesberg FE (2007) Efforts toward expansion of the genetic alphabet: structure and
replication of unnatural base pairs. Journal of the American Chemical Society. [IF=2.573, Cited=44, 17685517].
- Liu CC, Brustad E, Liu W, Schultz PG (2007) Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
Journal of the American Chemical Society. [IF=2.573, Cited=36, 17685615].
- Graziano JJ, Liu W, Perera R, ..., Schultz PG (2007) Selecting folded proteins from a library of secondary structural
elements. Journal of the American Chemical Society. [IF=2.573, Cited=11, 18067292].
- Seyedsayamdost MR, Xie J, Chan CTY, ..., Stubbe J (2007) Site-specific insertion of 3-aminotyrosine into subunit alpha2
of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation. Journal of
the American Chemical Society. [IF=2.573, Cited=84, 17990884].
- Minnihan EC, Young DD, Schultz PG, Stubbe J (2011) Incorporation of fluorotyrosines into ribonucleotide reductase using
an evolved, polyspecific aminoacyl-tRNA synthetase. Journal of the American Chemical Society. [IF=2.573, Cited=55, 21913683].
- Tianero MDB, Donia MS, Young TS, ..., Schmidt EW (2011) Ribosomal route to small-molecule diversity. Journal of the
American Chemical Society. [IF=2.573, Cited=74, 22107593].
- Kim CH, Axup JY, Dubrovska A, ..., Schultz PG (2012) Synthesis of bispecific antibodies using genetically encoded
unnatural amino acids. Journal of the American Chemical Society. [IF=2.573, Cited=78, 22642368].
- Shen W, Tremblay MS, Deshmukh VA, ..., Schultz PG (2013) Small-molecule inducer of β cell proliferation identified by
high-throughput screening. Journal of the American Chemical Society. [IF=2.573, Cited=52, 23330637].
- Kazane SA, Axup JY, Kim CH, ..., Smider VV (2012) Self-assembled antibody multimers through peptide nucleic acid
conjugation. Journal of the American Chemical Society. [IF=2.573, Cited=38, 23210862].
- Sun SB, Sen S, Kim NJ, ..., Wang F (2013) Mutational analysis of 48G7 reveals that somatic hypermutation affects both
antibody stability and binding affinity. Journal of the American Chemical Society. [IF=2.573, Cited=18, 23795814].
- Lu H, Wang D, Kazane S, ..., Schultz PG (2013) Site-specific antibody-polymer conjugates for siRNA delivery. Journal of
the American Chemical Society. [IF=2.573, Cited=43, 23924037].
- Chatterjee A, Guo J, Lee HS, Schultz PG (2013) A genetically encoded fluorescent probe in mammalian cells. Journal of
the American Chemical Society. [IF=2.573, Cited=97, 23924161].
- Furman JL, Kang M, Choi S, ..., Kim CH (2014) A genetically encoded aza-Michael acceptor for covalent cross-linking of
protein-receptor complexes. Journal of the American Chemical Society. [IF=2.573, Cited=55, 24846839].
- Liu T, Liu Y, Wang Y, ..., Wang F (2014) Rational design of CXCR4 specific antibodies with elongated CDRs. Journal of
the American Chemical Society. [IF=2.573, Cited=18, 25041362].
- Liu T, Fu G, Luo X, ..., Wang F (2015) Rational design of antibody protease inhibitors. Journal of the American Chemical
Society. [IF=2.573, Cited=11, 25775396].
- Cellitti SE, Jones DH, Lagpacan L, ..., Geierstanger BH (2008) In vivo incorporation of unnatural amino acids to probe
structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy. Journal of the
American Chemical Society. [IF=2.573, Cited=94, 18576636].
- Lee HS, Schultz PG (2008) Biosynthesis of a site-specific DNA cleaving protein. Journal of the American Chemical
Society. [IF=2.573, Cited=42, 18788806].
- Brustad EM, Lemke EA, Schultz PG, Deniz AA (2008) A general and efficient method for the site-specific dual-labeling of
proteins for single molecule fluorescence resonance energy transfer. Journal of the American Chemical Society.
[IF=2.573, Cited=97, 19108697].
- Lee HS, Spraggon G, Schultz PG, Wang F (2009) Genetic incorporation of a metal-ion chelating amino acid into proteins as
a biophysical probe. Journal of the American Chemical Society. [IF=2.573, Cited=63, 19193005].
- Wu X, Schultz PG (2009) Synthesis at the interface of chemistry and biology. Journal of the American Chemical Society.
[IF=2.573, Cited=50, 19689159].
- Lemke EA, Gambin Y, Vandelinder V, ..., Deniz AA (2009) Microfluidic device for single-molecule experiments with
enhanced photostability. Journal of the American Chemical Society. [IF=2.573, Cited=41, 19772358].
- Liu CC, Mack AV, Brustad EM, ..., Schultz PG (2009) Evolution of proteins with genetically encoded "chemical warheads".
Journal of the American Chemical Society. [IF=2.573, Cited=46, 19555063].
- Lee HS, Guo J, Lemke EA, ..., Schultz PG (2009) Genetic incorporation of a small, environmentally sensitive, fluorescent
probe into proteins in Saccharomyces cerevisiae. Journal of the American Chemical Society. [IF=2.573, Cited=110, 19702307].
- Zambaldo C, Vinogradova EV, Qi X, ..., Bollong MJ (2020) 2-Sulfonylpyridines as Tunable, Cysteine-Reactive
Electrophiles. Journal of the American Chemical Society. [IF=2.573, Cited=33, 32302104].
- Kim MS, Ma JSY, Yun H, ..., Kim CH (2015) Redirection of genetically engineered CAR-T cells using bifunctional small
molecules. Journal of the American Chemical Society. [IF=2.573, Cited=90, 25692571].
- Mehta AP, Li H, Reed SA, ..., Schultz PG (2016) Replacement of Thymidine by a Modified Base in the Escherichia coli
Genome. Journal of the American Chemical Society. [IF=2.573, Cited=12, 27213685].
- Mehta AP, Li H, Reed SA, ..., Schultz PG (2016) Replacement of 2'-Deoxycytidine by 2'-Deoxycytidine Analogues in the E.
coli Genome. Journal of the American Chemical Society. [IF=2.573, Cited=9, 27762133].
- Koh M, Nasertorabi F, Han GW, ..., Schultz PG (2017) Generation of an Orthogonal Protein-Protein Interface with a
Noncanonical Amino Acid. Journal of the American Chemical Society. [IF=2.573, Cited=12, 28413876].
- Zambaldo C, Luo X, Mehta AP, Schultz PG (2017) Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino
Acids. Journal of the American Chemical Society. [IF=2.573, Cited=21, 28809560].
- Xuan W, Yao A, Schultz PG (2017) Genetically Encoded Fluorescent Probe for Detecting Sirtuins in Living Cells. Journal
of the American Chemical Society. [IF=2.573, Cited=11, 28857557].
- Du J, Cao Y, Liu Y, ..., Wang F (2017) Engineering Bifunctional Antibodies with Constant Region Fusion Architectures.
Journal of the American Chemical Society. [IF=2.573, Cited=4, 29186655].
- Gan F, Liu R, Wang F, Schultz PG (2018) Functional Replacement of Histidine in Proteins To Generate Noncanonical Amino
Acid Dependent Organisms. Journal of the American Chemical Society. [IF=2.573, Cited=18, 29509426].
- Mehta AP, Wang Y, Reed SA, ..., Schultz PG (2018) Bacterial Genome Containing Chimeric DNA-RNA Sequences. Journal of the
American Chemical Society. [IF=2.573, Cited=5, 30160955].
- Li JC, Liu T, Wang Y, ..., Schultz PG (2018) Enhancing Protein Stability with Genetically Encoded Noncanonical Amino
Acids. Journal of the American Chemical Society. [IF=2.573, Cited=25, 30433771].
- Koh M, Yao A, Gleason PR, ..., Schultz PG (2019) A General Strategy for Engineering Noncanonical Amino Acid Dependent
Bacterial Growth. Journal of the American Chemical Society. [IF=2.573, Cited=9, 31580059].
- Chang YT, Wignall SM, Rosania GR, ..., Schultz PG (2001) Synthesis and biological evaluation of myoseverin derivatives:
microtubule assembly inhibitors. Journal of Medicinal Chemistry. [IF=1.655, Cited=15, 11741468].
- Ding S, Gray NS, Ding Q, Schultz PG (2001) A concise and traceless linker strategy toward combinatorial libraries of
2,6,9-substituted purines. Journal of Organic Chemistry. [IF=0.885, Cited=9, 11722241].
- Wang L, Xie J, Deniz AA, Schultz PG (2003) Unnatural amino acid mutagenesis of green fluorescent protein. Journal of
Organic Chemistry. [IF=0.885, Cited=56, 12515477].
- Thielges MC, Axup JY, Wong D, ..., Fayer MD (2011) Two-dimensional IR spectroscopy of protein dynamics using two
vibrational labels: a site-specific genetically encoded unnatural amino acid and an active site ligand. Journal of
Physical Chemistry B. [IF=0.893, Cited=48, 21823631].
- Wu TY, Ding S, Gray NS, Schultz PG (2001) Solid-phase synthesis of 2,3,5-trisubstituted indoles. Organic Letters.
[IF=1.091, Cited=5, 11720546].
- Wu TYH, Schultz PG (2002) A versatile linkage strategy for solid-phase synthesis of N,N-dimethyltryptamines and beta-
carbolines. Organic Letters. [IF=1.091, Cited=3, 12423079].
- Wu TYH, Schultz PG, Ding S (2003) One-pot two-step microwave-assisted reaction in constructing 4,5-disubstituted
pyrazolopyrimidines. Organic Letters. [IF=1.091, Cited=12, 14507179].
- Schultz PG, Lerner RA (2002) Completing the circle. Nature. [IF=11.591, Cited=11, 12152057].
- Yu S, Pearson AD, Lim RK, ..., Tremblay MS (2016) Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune
Cells via an Antibody-drug Conjugate. Molecular Therapy. [IF=1.72, Cited=19, 27731313].
- Deshmukh VA, Tardif V, Lyssiotis CA, ..., Lairson LL (2013) A regenerative approach to the treatment of multiple
sclerosis. Nature. [IF=11.591, Cited=283, 24107995].
- Luo X, Fu G, Wang RE, ..., Wang F (2017) Genetically encoding phosphotyrosine and its nonhydrolyzable analog in
bacteria. Nature Chemical Biology. [IF=2.623, Cited=64, 28604693].
- Bakowski MA, Beutler N, Wolff KC, ..., Rogers TF (2021) Drug repurposing screens identify chemical entities for the
development of COVID-19 interventions. Nature Communications. [IF=3.268, Cited=56, 34083527].
- Bollong MJ, Lee G, Coukos JS, ..., Moellering RE (2018) A metabolite-derived protein modification integrates glycolysis
with KEAP1-NRF2 signalling. Nature. [IF=11.591, Cited=123, 30323285].
- Shalhout SZ, Yang PY, Grzelak EM, ..., Bollong MJ (2021) YAP-dependent proliferation by a small molecule targeting
annexin A2. Nature Chemical Biology. [IF=2.623, Cited=21, 33723431].
- Lee SJ, Mahankali M, Bitar A, ..., Shen W (2017) A Novel Role for RARα Agonists as Apolipoprotein CIII Inhibitors
Identified from High Throughput Screening. Scientific Reports. [IF=1.312, Cited=8, 28724938].
- Su AI, Cooke MP, Ching KA, ..., Hogenesch JB (2002) Large-scale analysis of the human and mouse transcriptomes.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=1000, 11904358].
- Santoro SW, Schultz PG (2002) Directed evolution of the site specificity of Cre recombinase. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=104, 11904359].
- Wang L, Zhang Z, Brock A, Schultz PG (2002) Addition of the keto functional group to the genetic code of Escherichia
coli. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=211, 12518054].
- Yin J, Andryski SE, Beuscher AE, ..., Schultz PG (2003) Structural evidence for substrate strain in antibody catalysis.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=28, 12552112].
- Zhang Z, Alfonta L, Tian F, ..., Schultz PG (2004) Selective incorporation of 5-hydroxytryptophan into proteins in
mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=81, 15187228].
- Huang Q, Raya A, DeJesus P, ..., Schultz PG (2004) Identification of p53 regulators by genome-wide functional analysis.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=102, 14990790].
- Anderson JC, Wu N, Santoro SW, ..., Schultz PG (2004) An expanded genetic code with a functional quadruplet codon.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=182, 15138302].
- Torres FE, Kuhn P, De Bruyker D, ..., Bruce RH (2004) Enthalpy arrays. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=52, 15210951].
- Liu J, Bang AG, Kintner C, ..., Schultz PG (2005) Identification of the Wnt signaling activator leucine-rich repeat in
Flightless interaction protein 2 by a genome-wide functional analysis. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=51, 15677333].
- Melnick JS, Janes J, Kim S, ..., Caldwell JS (2006) An efficient rapid system for profiling the cellular activities of
molecular libraries. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=112, 16492761].
- Collins CS, Hong J, Sapinoso L, ..., Hampton GM (2006) A small interfering RNA screen for modulators of tumor cell
motility identifies MAP4K4 as a promigratory kinase. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=129, 16537454].
- Berezhna SY, Supekova L, Supek F, ..., Deniz AA (2006) siRNA in human cells selectively localizes to target RNA sites.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=51, 16684885].
- Turner JM, Graziano J, Spraggon G, Schultz PG (2006) Structural plasticity of an aminoacyl-tRNA synthetase active site.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=34, 16618920].
- Summerer D, Chen S, Wu N, ..., Schultz PG (2006) A genetically encoded fluorescent amino acid. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=124, 16785423].
- Mukherji M, Bell R, Supekova L, ..., Schultz PG (2006) Genome-wide functional analysis of human cell-cycle regulators.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=95, 17001007].
- Chen S, Do JT, Zhang Q, ..., Ding S (2006) Self-renewal of embryonic stem cells by a small molecule. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=178, 17088537].
- Galkin AV, Melnick JS, Kim S, ..., Warmuth M (2006) Identification of NVP-TAE684, a potent, selective, and efficacious
inhibitor of NPM-ALK. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=217, 17185414].
- Liu Y, Kern JT, Walker JR, ..., Luesch H (2007) A genomic screen for activators of the antioxidant response element.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=111, 17360324].
- Gumireddy K, Sun F, Klein-Szanto AJ, ..., Huang Q (2007) In vivo selection for metastasis promoting genes in the mouse.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=56, 17420453].
- Zhang Q, Major MB, Takanashi S, ..., Ding S (2007) Small-molecule synergist of the Wnt/beta-catenin signaling pathway.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=76, 17460038].
- Chen S, Takanashi S, Zhang Q, ..., Schultz PG (2007) Reversine increases the plasticity of lineage-committed mammalian
cells. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=59, 17566101].
- Lyssiotis CA, Walker J, Wu C, ..., Wu X (2007) Inhibition of histone deacetylase activity induces developmental
plasticity in oligodendrocyte precursor cells. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=84, 17855562].
- Ding S, Wu TYH, Brinker A, ..., Schultz PG (2003) Synthetic small molecules that control stem cell fate. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=201, 12794184].
- Dubrovska A, Kim S, Salamone RJ, ..., Reddy VA (2008) The role of PTEN/Akt/PI3K signaling in the maintenance and
viability of prostate cancer stem-like cell populations. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=356, 19116269].
- Hirota T, Lewis WG, Liu AC, ..., Kay SA (2008) A chemical biology approach reveals period shortening of the mammalian
circadian clock by specific inhibition of GSK-3beta. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=184, 19104043].
- Wang W, Walker JR, Wang X, ..., Schultz PG (2009) Identification of small-molecule inducers of pancreatic beta-cell
expansion. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=57, 19164755].
- Deniz AA, Laurence TA, Beligere GS, ..., Weiss S (2000) Single-molecule protein folding: diffusion fluorescence
resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2. Proceedings of the National Academy
of Sciences of the United States of America. [IF=2.765, Cited=224, 10792044].
- Lyssiotis CA, Foreman RK, Staerk J, ..., Jaenisch R (2009) Reprogramming of murine fibroblasts to induced pluripotent
stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=211, 19447925].
- Zhu S, Wurdak H, Wang Y, ..., Wu X (2009) A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=64, 19805117].
- Fleissner MR, Brustad EM, Kálai T, ..., Hubbell WL (2009) Site-directed spin labeling of a genetically encoded unnatural
amino acid. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=117, 19995976].
- Gonzalez R, Jennings LL, Knuth M, ..., Lesley SA (2010) Screening the mammalian extracellular proteome for regulators of
embryonic human stem cell pluripotency. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=64, 20133595].
- Supekova L, Supek F, Greer JE, Schultz PG (2010) A single mutation in the first transmembrane domain of yeast COX2
enables its allotopic expression. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=21, 20194738].
- Hu XV, Rodrigues TMA, Tao H, ..., Wu X (2010) Identification of RING finger protein 4 (RNF4) as a modulator of DNA
demethylation through a functional genomics screen. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=45, 20696907].
- Wurdak H, Zhu S, Min KH, ..., Schultz PG (2010) A small molecule accelerates neuronal differentiation in the adult rat.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=57, 20823227].
- Xia G, Chen L, Sera T, ..., Romesberg FE (2002) Directed evolution of novel polymerase activities: mutation of a DNA
polymerase into an efficient RNA polymerase. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=79, 12011423].
- Cho H, Daniel T, Buechler YJ, ..., Kimmel BE (2011) Optimized clinical performance of growth hormone with an expanded
genetic code. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=101, 21576502].
- Young TS, Young DD, Ahmad I, ..., Schultz PG (2011) Evolution of cyclic peptide protease inhibitors. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=70, 21690365].
- Gauba V, Grünewald J, Gorney V, ..., Ramirez-Montagut T (2011) Loss of CD4 T-cell-dependent tolerance to proteins with
modified amino acids. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=38, 21768354].
- Liu J, Johnson K, Li J, ..., Schultz PG (2011) Regenerative phenotype in mice with a point mutation in transforming
growth factor beta type I receptor (TGFBR1). Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=31, 21841138].
- Watanabe CM, Wolffram S, Ader P, ..., Gohil K (2001) The in vivo neuromodulatory effects of the herbal medicine ginkgo
biloba. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=120, 11381109].
- Axup JY, Bajjuri KM, Ritland M, ..., Schultz PG (2012) Synthesis of site-specific antibody-drug conjugates using
unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=256, 22988081].
- Chatterjee A, Xiao H, Schultz PG (2012) Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for
unnatural amino acid mutagenesis in Escherichia coli. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=65, 22927411].
- Boitano AE, de Lichtervelde L, Snead JL, ..., Schultz PG (2012) An image-based screen identifies a small molecule
regulator of megakaryopoiesis. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=13, 22891346].
- Su AI, Guidotti LG, Pezacki JP, ..., Schultz PG (2002) Gene expression during the priming phase of liver regeneration
after partial hepatectomy in mice. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=126, 12177410].
- Wang F, Sen S, Zhang Y, ..., Schultz PG (2013) Somatic hypermutation maintains antibody thermodynamic stability during
affinity maturation. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=48, 23440204].
- Wang F, Sambandan D, Halder R, ..., Schultz PG (2013) Identification of a small molecule with activity against drug-
resistant and persistent tuberculosis. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=106, 23776209].
- Chatterjee A, Xiao H, Bollong M, ..., Schultz PG (2013) Efficient viral delivery system for unnatural amino acid
mutagenesis in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=69, 23818609].
- Kim CH, Axup JY, Lawson BR, ..., Schultz PG (2013) Bispecific small molecule-antibody conjugate targeting prostate
cancer. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=50, 24127589].
- Tian F, Lu Y, Manibusan A, ..., Sapra P (2014) A general approach to site-specific antibody drug conjugates. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=136, 24443552].
- Liu T, Zhang Y, Liu Y, ..., Wang F (2015) Functional human antibody CDR fusions as long-acting therapeutic endocrine
agonists. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=22, 25605877].
- Harbut MB, Vilchèze C, Luo X, ..., Wang F (2015) Auranofin exerts broad-spectrum bactericidal activities by targeting
thiol-redox homeostasis. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=161, 25831516].
- Xiao H, Nasertorabi F, Choi SH, ..., Schultz PG (2015) Exploring the potential impact of an expanded genetic code on
protein function. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=35, 26038548].
- Rodgers DT, Mazagova M, Hampton EN, ..., Young TS (2016) Switch-mediated activation and retargeting of CAR-T cells for
B-cell malignancies. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=216, 26759369].
- Ma JSY, Kim JY, Kazane SA, ..., Cao Y (2016) Versatile strategy for controlling the specificity and activity of
engineered T cells. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=163, 26759368].
- Yang PY, Zou H, Chao E, ..., Shen W (2016) Engineering a long-acting, potent GLP-1 analog for microstructure-based
transdermal delivery. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=21, 27035989].
- Luo X, Zambaldo C, Liu T, ..., Young TS (2016) Recombinant thiopeptides containing noncanonical amino acids. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=33, 26976568].
- Liu T, Wang Y, Luo X, ..., Schultz PG (2016) Enhancing protein stability with extended disulfide bonds. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=64, 27162342].
- Wang RE, Wang Y, Zhang Y, ..., Wang F (2016) Rational design of a Kv1.3 channel-blocking antibody as a selective
immunosuppressant. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=18, 27663736].
- Bollong MJ, Yang B, Vergani N, ..., Schultz PG (2017) Small molecule-mediated inhibition of myofibroblast
transdifferentiation for the treatment of fibrosis. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=41, 28416697].
- Bollong MJ, Pietilä M, Pearson AD, ..., Lairson LL (2017) A vimentin binding small molecule leads to mitotic disruption
in mesenchymal cancers. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=39, 29087350].
- Chin JW, Martin AB, King DS, ..., Schultz PG (2002) Addition of a photocrosslinking amino acid to the genetic code of
Escherichiacoli. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=398, 12154230].
- Winssinger N, Ficarro S, Schultz PG, Harris JL (2002) Profiling protein function with small molecule microarrays.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=78, 12167675].
- Wang J, Schultz PG, Johnson KA (2018) Mechanistic studies of a small-molecule modulator of SMN2 splicing. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=65, 29712837].
- Mehta AP, Supekova L, Chen JH, ..., Schultz PG (2018) Engineering yeast endosymbionts as a step toward the evolution of
mitochondria. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=20, 30373839].
- Lucki NC, Villa GR, Vergani N, ..., Lairson LL (2019) A cell type-selective apoptosis-inducing small molecule for the
treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=14, 30846550].
- Zhang Y, Fang C, Wang RE, ..., Wang F (2019) A tumor-targeted immune checkpoint blocker. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=13, 31332018].
- Spence MM, Rubin SM, Dimitrov IE, ..., Schultz PG (2001) Functionalized xenon as a biosensor. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=146, 11535830].
- Shao S, Koh M, Schultz PG (2020) Expanding the genetic code of the human hematopoietic system. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=7, 32253306].
- Chanda SK, White S, Orth AP, ..., Caldwell JS (2003) Genome-scale functional profiling of the mammalian AP-1 signaling
pathway. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=66, 14514886].
- Koh M, Ahmad I, Ko Y, ..., Bollong MJ (2021) A short ORF-encoded transcriptional regulator. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=22, 33468658].
- Su AI, Pezacki JP, Wodicka L, ..., Chisari FV (2002) Genomic analysis of the host response to hepatitis C virus
infection. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=464, 12441396].
- Zheng L, Liu J, Batalov S, ..., Schultz PG (2003) An approach to genomewide screens of expressed small interfering RNAs
in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=132, 14688408].
- Ko Y, Hong M, Lee S, ..., Bollong MJ (2023) S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite
activates NRF2 signaling. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=7, 37155889].
- Schultz PG (2023) Christopher T. Walsh: Science, mentorship, and service. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=0, 36857341].
- Grzelak EM, Elshan NGRD, Shao S, ..., Bollong MJ (2023) Pharmacological YAP activation promotes regenerative repair of
cutaneous wounds. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=3, 37399395].
- Shao S, Zhang N, Specht GP, ..., Bollong MJ (2024) Pharmacological expansion of type 2 alveolar epithelial cells
promotes regenerative lower airway repair. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=0, 38598345].
- Salomon AR, Ficarro SB, Brill LM, ..., Peters EC (2003) Profiling of tyrosine phosphorylation pathways in human cells
using mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=161, 12522270].
- Yao S, Anex DS, Caldwell WB, ..., Schultz PG (1999) SDS capillary gel electrophoresis of proteins in microfabricated
channels. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=58, 10318890].
- Liu DR, Liu DR, Schultz PG, Schultz PG (1999) Progress toward the evolution of an organism with an expanded genetic
code. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=94, 10220370].
- Supekova L, Supek F, Lee J, ..., Schultz PG (2007) Identification of human kinases involved in hepatitis C virus
replication by small interference RNA library screening. Journal of Biological Chemistry. [IF=1.122, Cited=80, 17951261].
- Block-Alper L, Webster P, Zhou X, ..., Meyer DI (2002) IN02, a positive regulator of lipid biosynthesis, is essential
for the formation of inducible membranes in yeast. Molecular Biology of the Cell. [IF=0.848, Cited=17, 11809821].
- Larman HB, Scott ER, Wogan M, ..., Schultz PG (2014) Sensitive, multiplex and direct quantification of RNA sequences
using a modified RASL assay. Nucleic Acids Research. [IF=4.663, Cited=18, 25063296].
- Xiao H, Schultz PG (2016) At the Interface of Chemical and Biological Synthesis: An Expanded Genetic Code. Cold Spring
Harbor perspectives in biology. [IF=1.926, Cited=62, 27413101].
- Zhang Z, English BP, Grimm JB, ..., Tjian R (2016) Rapid dynamics of general transcription factor TFIIB binding during
preinitiation complex assembly revealed by single-molecule analysis. Genes and Development. [IF=1.985, Cited=45, 27798851].
- Zhong L, Tran T, Baguley TD, ..., Shen W (2018) A novel inhibitor of inducible NOS dimerization protects against
cytokine-induced rat beta cell dysfunction. British Journal of Pharmacology. [IF=1.816, Cited=4, 29888783].
- Lee SC, Ma JSY, Kim MS, ..., Young TS (2021) A PSMA-targeted bispecific antibody for prostate cancer driven by a small-
molecule targeting ligand. Science advances. [IF=2.861, Cited=8, 34380625].
- Wang L, Brock A, Herberich B, Schultz PG (2001) Expanding the genetic code of Escherichia coli. Science. [IF=7.729,
Cited=747, 11313494].
- Chin JW, Cropp TA, Anderson JC, ..., Schultz PG (2003) An expanded eukaryotic genetic code. Science. [IF=7.729,
Cited=450, 12920298].
- Zhang Z, Gildersleeve J, Yang YY, ..., Schultz PG (2004) A new strategy for the synthesis of glycoproteins. Science.
[IF=7.729, Cited=87, 14726590].
- Willingham AT, Orth AP, Batalov S, ..., Schultz PG (2005) A strategy for probing the function of noncoding RNAs finds a
repressor of NFAT. Science. [IF=7.729, Cited=501, 16141075].
- Debler EW, Kaufmann GF, Meijler MM, ..., Lerner RA (2008) Deeply inverted electron-hole recombination in a luminescent
antibody-stilbene complex. Science. [IF=7.729, Cited=28, 18309081].
- Boitano AE, Wang J, Romeo R, ..., Cooke MP (2010) Aryl hydrocarbon receptor antagonists promote the expansion of human
hematopoietic stem cells. Science. [IF=7.729, Cited=628, 20688981].
- Meister S, Plouffe DM, Kuhen KL, ..., Winzeler EA (2011) Imaging of Plasmodium liver stages to drive next-generation
antimalarial drug discovery. Science. [IF=7.729, Cited=205, 22096101].
- Johnson K, Zhu S, Tremblay MS, ..., Schultz PG (2012) A stem cell-based approach to cartilage repair. Science.
[IF=7.729, Cited=353, 22491093].
- Hirota T, Lee JW, St John PC, ..., Kay SA (2012) Identification of small molecule activators of cryptochrome. Science.
[IF=7.729, Cited=266, 22798407].
- Lajoie MJ, Rovner AJ, Goodman DB, ..., Isaacs FJ (2013) Genomically recoded organisms expand biological functions.
Science. [IF=7.729, Cited=430, 24136966].
- Ly DH, Lockhart DJ, Lerner RA, Schultz PG (2000) Mitotic misregulation and human aging. Science. [IF=7.729, Cited=353, 10741968].
- Guo Z, Zhou D, Schultz PG (2000) Designing small-molecule switches for protein-protein interactions. Science. [IF=7.729,
Cited=49, 10856217].
- Simeonov A, Matsushita M, Juban EA, ..., Janda KD (2000) Blue-fluorescent antibodies. Science. [IF=7.729, Cited=40, 11030644].
- Zhang Z, Gildersleeve J, Yang YY, ..., Schultz PG (2009) Retraction. Science. [IF=7.729, Cited=8, 19965450].
- Pearson AD, Mills JH, Song Y, ..., Schultz PG (2015) Transition states. Trapping a transition state in a computationally
designed protein bottle. Science. [IF=7.729, Cited=22, 25700516].
- Chin EN, Yu C, Vartabedian VF, ..., Lairson LL (2020) Antitumor activity of a systemic STING-activating non-nucleotide
cGAMP mimetic. Science. [IF=7.729, Cited=143, 32820126].
- Lairson LL, Lyssiotis CA, Zhu S, Schultz PG (2013) Small molecule-based approaches to adult stem cell therapies. Annual
Review of Pharmacology and Toxicology. [IF=2.886, Cited=19, 23294307].
- Liu CC, Schultz PG (2010) Adding new chemistries to the genetic code. Annual Review of Biochemistry. [IF=5.273,
Cited=880, 20307192].
- Wang L, Xie J, Schultz PG (2006) Expanding the genetic code. None. [IF=None, Cited=301, 16689635].
- Deniz AA, Laurence TA, Dahan M, ..., Weiss S (2001) Ratiometric single-molecule studies of freely diffusing
biomolecules. Annual Review of Physical Chemistry. [IF=3.733, Cited=100, 11326065].
- Mirotsou M, Watanabe CMH, Schultz PG, ..., Dzau VJ (2003) Elucidating the molecular mechanism of cardiac remodeling
using a comparative genomic approach. Physiological Genomics. [IF=0.843, Cited=21, 12902547].
- Dubrovska A, Elliott J, Salamone RJ, ..., Schultz PG (2010) Combination therapy targeting both tumor-initiating and
differentiated cell populations in prostate carcinoma. Clinical Cancer Research. [IF=2.156, Cited=81, 21138868].
- Love MS, Beasley FC, Jumani RS, ..., McNamara CW (2017) A high-throughput phenotypic screen identifies clofazimine as a
potential treatment for cryptosporidiosis. PLoS Neglected Tropical Diseases. [IF=1.335, Cited=64, 28158186].
- Wilburn KM, Montague CR, Qin B, ..., VanderVen BC (2022) Pharmacological and genetic activation of cAMP synthesis
disrupts cholesterol utilization in Mycobacterium tuberculosis. PLoS Pathogens. [IF=1.423, Cited=7, 35134095].
- Laborda E, Mazagova M, Shao S, ..., Young TS (2017) Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-
Like Molecule-1 for Human Acute Myeloid Leukemia. International Journal of Molecular Sciences. [IF=1.263, Cited=39, 29077054].
- Zhu S, Wurdak H, Schultz PG (2010) Directed embryonic stem cell differentiation with small molecules. Future Medicinal
Chemistry. [IF=0.829, Cited=7, 21426114].
Publication with MISMATCHING institution:
- Pollitt SK, Schultz PG (1998) A Photochemical Switch for Controlling Protein-Protein Interactions. Angewandte Chemie -
International Edition. [IF=2.456, Cited=3, 29711048].
- Loweth CJ, Caldwell WB, Peng X, ..., Schultz PG (1999) DNA-Based Assembly of Gold Nanocrystals. Angewandte Chemie -
International Edition. [IF=2.456, Cited=87, 29711189].
- Wang Y, Du J, Zou H, ..., Wang F (2016) Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon,
and Glucose-Dependent Insulinotropic Polypeptide Receptors. Angewandte Chemie - International Edition. [IF=2.456,
Cited=12, 27595986].
- Diercks CS, Dik DA, Schultz PG (2021) Adding New Chemistries to the Central Dogma of Molecular Biology. Chem. [IF=2.863,
Cited=2, 37621702].
- Park Y, Luo J, Schultz PG, Kirsch JF (1997) Noncoded amino acid replacement probes of the aspartate aminotransferase
mechanism. Biochemistry. [IF=0.753, Cited=7, 9265632].
- Koh JT, Cornish VW, Schultz PG (1997) An experimental approach to evaluating the role of backbone interactions in
proteins using unnatural amino acid mutagenesis. Biochemistry. [IF=0.753, Cited=61, 9298950].
- Blackwood ME, Rush TS, Romesberg F, ..., Spiro TG (1998) Alternative modes of substrate distortion in enzyme and
antibody catalyzed ferrochelation reactions. Biochemistry. [IF=0.753, Cited=32, 9457047].
- Romesberg FE, Santarsiero BD, Spiller B, ..., Stevens RC (1998) Structural and kinetic evidence for strain in biological
catalysis. Biochemistry. [IF=0.753, Cited=21, 9772166].
- Liu Y, Barrett JE, Schultz PG, Santi DV (1999) Tyrosine 146 of thymidylate synthase assists proton abstraction from the
5-position of 2'-deoxyuridine 5'-monophosphate. Biochemistry. [IF=0.753, Cited=9, 9888826].
- Nam TG, McNamara CW, Bopp S, ..., Winzeler EA (2011) A chemical genomic analysis of decoquinate, a Plasmodium falciparum
cytochrome b inhibitor. ACS Chemical Biology. [IF=0.963, Cited=62, 21866942].
- Grunwell JR, Glass JL, Lacoste TD, ..., Schultz PG (2001) Monitoring the conformational fluctuations of DNA hairpins
using single-pair fluorescence resonance energy transfer. Journal of the American Chemical Society. [IF=2.573,
Cited=58, 11457196].
- Zhang Y, Liu Y, Wang Y, ..., Wang F (2014) Rational design of humanized dual-agonist antibodies. Journal of the American
Chemical Society. [IF=2.573, Cited=14, 25494484].
- Dik DA, Zhang N, Chen JS, ..., Schultz PG (2020) Semisynthesis of a Bacterium with Non-canonical Cell-Wall Cross-Links.
Journal of the American Chemical Society. [IF=2.573, Cited=8, 32510943].
- Wang RE, Liu T, Wang Y, ..., Schultz PG (2015) An immunosuppressive antibody-drug conjugate. Journal of the American
Chemical Society. [IF=2.573, Cited=49, 25699419].
- Kern JC, Cancilla M, Dooney D, ..., Garbaccio RM (2016) Discovery of Pyrophosphate Diesters as Tunable, Soluble, and
Bioorthogonal Linkers for Site-Specific Antibody-Drug Conjugates. Journal of the American Chemical Society. [IF=2.573,
Cited=58, 26745435].
- Mehta AP, Ko Y, Supekova L, ..., Schultz PG (2019) Toward a Synthetic Yeast Endosymbiont with a Minimal Genome. Journal
of the American Chemical Society. [IF=2.573, Cited=4, 31419116].
- Verdugo DE, Cancilla MT, Ge X, ..., Bertozzi CR (2001) Discovery of estrogen sulfotransferase inhibitors from a purine
library screen. Journal of Medicinal Chemistry. [IF=1.655, Cited=23, 11495578].
- Ardestani A, Li S, Annamalai K, ..., Maedler K (2019) Neratinib protects pancreatic beta cells in diabetes. Nature
Communications. [IF=3.268, Cited=28, 31676778].
- Pigula M, Lai YC, Koh M, ..., Schultz PG (2024) An unnatural amino acid dependent, conditional Pseudomonas vaccine
prevents bacterial infection. Nature Communications. [IF=3.268, Cited=0, 39117651].
- Riva L, Yuan S, Yin X, ..., Chanda SK (2020) Discovery of SARS-CoV-2 antiviral drugs through large-scale compound
repurposing. Nature. [IF=11.591, Cited=457, 32707573].
- Riva L, Yuan S, Yin X, ..., Chanda SK (2024) Author Correction: Discovery of SARS-CoV-2 antiviral drugs through large-
scale compound repurposing. Nature. [IF=11.591, Cited=0, 38890463].
- Plouffe D, Brinker A, McNamara C, ..., Winzeler EA (2008) In silico activity profiling reveals the mechanism of action
of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=276, 18579783].
- Grünewald J, Tsao ML, Perera R, ..., Schultz PG (2008) Immunochemical termination of self-tolerance. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=35, 18685087].
- Liu CC, Mack AV, Tsao ML, ..., Smider VV (2008) Protein evolution with an expanded genetic code. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=83, 19004806].
- Wikoff WR, Anfora AT, Liu J, ..., Siuzdak G (2009) Metabolomics analysis reveals large effects of gut microflora on
mammalian blood metabolites. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=1000, 19234110].
- Grünewald J, Hunt GS, Dong L, ..., Smider VV (2009) Mechanistic studies of the immunochemical termination of self-
tolerance with unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=36, 19246393].
- Kazane SA, Sok D, Cho EH, ..., Smider VV (2012) Site-specific DNA-antibody conjugates for specific and sensitive immuno-
PCR. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=63, 22345566].
- Liu J, Pan S, Hsieh MH, ..., Harris JL (2013) Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=463, 24277854].
- Lesley SA, Kuhn P, Godzik A, ..., Stevens RC (2002) Structural genomics of the Thermotoga maritima proteome implemented
in a high-throughput structure determination pipeline. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=297, 12193646].
- Bouvard C, Lim SM, Ludka J, ..., Zhu S (2017) Small molecule selectively suppresses MYC transcription in cancer cells.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=17, 28292893].
- Miglianico M, Eldering M, Slater H, ..., Dechering KJ (2018) Repurposing isoxazoline veterinary drugs for control of
vector-borne human diseases. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=31, 29967151].
- Zhang G, Baidin V, Pahil KS, ..., Kahne D (2018) Cell-based screen for discovering lipopolysaccharide biogenesis
inhibitors. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=49, 29735709].
- Janes J, Young ME, Chen E, ..., Schultz PG (2018) The ReFRAME library as a comprehensive drug repurposing library and
its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=104, 30282735].
- Simbulan-Rosenthal CM, Ly DH, Rosenthal DS, ..., Smulson ME (2000) Misregulation of gene expression in primary
fibroblasts lacking poly(ADP-ribose) polymerase. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=86, 11016956].
- Dik DA, Zhang N, Sturgell EJ, ..., Schultz PG (2021) A synthetic 5,3-cross-link in the cell wall of rod-shaped Gram-
positive bacteria. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=3, 33836615].
- Zuckermann RN, Schultz PG (1989) Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=11, 2467291].
- Pei D, Corey DR, Schultz PG (1990) Site-specific cleavage of duplex DNA by a semisynthetic nuclease via triple-helix
formation. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=29, 2124705].
- Jackson DY, Prudent JR, Baldwin EP, Schultz PG (1991) A mutagenesis study of a catalytic antibody. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=12, 1898778].
- Oldenburg KR, Loganathan D, Goldstein IJ, ..., Gallop MA (1992) Peptide ligands for a sugar-binding protein isolated
from a random peptide library. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=141, 1608948].
- Chung HH, Benson DR, Cornish VW, Schultz PG (1993) Probing the role of loop 2 in Ras function with unnatural amino
acids. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=18, 8234268].
- Lesley SA, Patten PA, Schultz PG (1993) A genetic approach to the generation of antibodies with enhanced catalytic
activities. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=18, 8094556].
- Jacobsen JR, Schultz PG (1994) Antibody catalysis of peptide bond formation. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=14, 8016084].
- Cornish VW, Benson DR, Altenbach CA, ..., Schultz PG (1994) Site-specific incorporation of biophysical probes into
proteins. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=108, 8159678].
- Huang L, Sera T, Schultz PG (1994) A permutational approach toward protein-DNA recognition. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=10, 8171021].
- Ku J, Schultz PG (1995) Alternate protein frameworks for molecular recognition. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=35, 7604031].
- Ulrich HD, Patten PA, Yang PL, ..., Schultz PG (1995) Expression studies of catalytic antibodies. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=44, 8524873].
- Hsieh-Wilson LC, Schultz PG, Stevens RC (1996) Insights into antibody catalysis: structure of an oxygenation catalyst at
1.9-angstrom resolution. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=20, 8643580].
- Sera T, Schultz PG (1996) In vivo selection of basic region-leucine zipper proteins with altered DNA-binding
specificities. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=12, 8610143].
- Liu DR, Liu DR, Magliery TJ, ..., Schultz PG (1997) Engineering a tRNA and aminoacyl-tRNA synthetase for the site-
specific incorporation of unnatural amino acids into proteins in vivo. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=93, 9294168].
- Kanamori T, Nishikawa S, Shin I, ..., Endo T (1997) Probing the environment along the protein import pathways in yeast
mitochondria by site-specific photocrosslinking. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=54, 9012810].
- Ma L, Hsieh-Wilson LC, Schultz PG (1998) Antibody catalysis of peptidyl-prolyl cis-trans isomerization in the folding of
RNase T1. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=7, 9636134].
- Pedersen H, Hölder S, Sutherlin DP, ..., Schultz PG (1998) A method for directed evolution and functional cloning of
enzymes. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=67, 9724736].
- Schultz PG (1998) Bringing biological solutions to chemical problems. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=3, 9843932].
- Yu J, Choi SY, Moon KD, ..., Schultz PG (1998) A glycosidase antibody elicited against a chair-like transition state
analog by in vitro immunization. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=8, 9501184].
- Ha T, Ha T, Ting AY, ..., Weiss S (1999) Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and
cleavage mechanism. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=215, 9927664].
- Kanamori T, Nishikawa S, Nakai M, ..., Endo T (1999) Uncoupling of transfer of the presequence and unfolding of the
mature domain in precursor translocation across the mitochondrial outer membrane. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=54, 10097089].
- Deniz AA, Dahan M, Grunwell JR, ..., Schultz PG (1999) Single-pair fluorescence resonance energy transfer on freely
diffusing molecules: observation of Förster distance dependence and subpopulations. Proceedings of the National Academy
of Sciences of the United States of America. [IF=2.765, Cited=236, 10097095].
- Rosania GR, Merlie J, Gray N, ..., Heald R (1999) A cyclin-dependent kinase inhibitor inducing cancer cell
differentiation: biochemical identification using Xenopus egg extracts. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=31, 10220373].
- Rampon C, Jiang CH, Dong H, ..., Hu Y (2000) Effects of environmental enrichment on gene expression in the brain.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=357, 11070096].
- Jiang CH, Tsien JZ, Schultz PG, Hu Y (2001) The effects of aging on gene expression in the hypothalamus and cortex of
mice. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=206, 11172053].
- Schultz PG, Schultz PG, Dervan PB, Dervan PB (1984) Distamycin and penta-N-methylpyrrolecarboxamide binding sites on
native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving. Journal of Biomolecular
Structure and Dynamics. [IF=1.22, Cited=29, 6101078].
- Hsieh LC, Yonkovich S, Kochersperger L, Schultz PG (1993) Controlling chemical reactivity with antibodies. Science.
[IF=7.729, Cited=20, 10049109].
- Ellman JA, Mendel D, Schultz PG (1992) Site-specific incorporation of novel backbone structures into proteins. Science.
[IF=7.729, Cited=80, 1553546].
- Mendel D, Ellman JA, Chang Z, ..., Schultz PG (1992) Probing protein stability with unnatural amino acids. Science.
[IF=7.729, Cited=59, 1615324].
- Pei DH, Ulrich HD, Schultz PG (1991) A combinatorial approach toward DNA recognition. Science. [IF=7.729, Cited=24, 1716784].
- Cochran AG, Schultz PG (1990) Antibody-catalyzed porphyrin metallation. Science. [IF=7.729, Cited=66, 2389144].
- Jacobsen JR, Prudent JR, Kochersperger L, ..., Schultz PG (1992) An efficient antibody-catalyzed aminoacylation
reaction. Science. [IF=7.729, Cited=23, 1566082].
- Noren CJ, Anthony-Cahill SJ, Griffith MC, Schultz PG (1989) A general method for site-specific incorporation of
unnatural amino acids into proteins. Science. [IF=7.729, Cited=454, 2649980].
- Baldwin E, Schultz PG (1989) Generation of a catalytic antibody by site-directed mutagenesis. Science. [IF=7.729,
Cited=30, 2672338].
- Müller WT, Klein DL, Lee T, ..., Schultz PG (1995) A strategy for the chemical synthesis of nanostructures. Science.
[IF=7.729, Cited=21, 17814791].
- Xiang XD, Sun X, Briceño G, ..., Schultz PG (1995) A combinatorial approach to materials discovery. Science. [IF=7.729,
Cited=101, 17834993].
- Patten PA, Gray NS, Yang PL, ..., Schultz PG (1996) The immunological evolution of catalysis. Science. [IF=7.729,
Cited=120, 8599084].
- Wedemayer GJ, Patten PA, Wang LH, ..., Stevens RC (1997) Structural insights into the evolution of an antibody combining
site. Science. [IF=7.729, Cited=327, 9180069].
- Romesberg FE, Spiller B, Schultz PG, Stevens RC (1998) Immunological origins of binding and catalysis in a Diels-
Alderase antibody. Science. [IF=7.729, Cited=74, 9506942].
- Gray NS, Wodicka L, Thunnissen AM, ..., Schultz PG (1998) Exploiting chemical libraries, structure, and genomics in the
search for kinase inhibitors. Science. [IF=7.729, Cited=420, 9677190].
- Schultz PG (1988) The interplay between chemistry and biology in the design of enzymatic catalysts. Science. [IF=7.729,
Cited=26, 2833815].
- Pollack SJ, Nakayama GR, Schultz PG (1988) Introduction of nucleophiles and spectroscopic probes into antibody combining
sites. Science. [IF=7.729, Cited=26, 3194752].
- Corey DR, Schultz PG (1987) Generation of a hybrid sequence-specific single-stranded deoxyribonuclease. Science.
[IF=7.729, Cited=51, 3685986].
- Pollack SJ, Jacobs JW, Schultz PG (1986) Selective chemical catalysis by an antibody. Science. [IF=7.729, Cited=208, 3787262].
- Schultz PG, Lerner RA (1995) From molecular diversity to catalysis: lessons from the immune system. Science. [IF=7.729,
Cited=166, 7569920].
- Cho CY, Moran EJ, Cherry SR, ..., Schultz PG (1993) An unnatural biopolymer. Science. [IF=7.729, Cited=72, 7689747].
- Prudent JR, Uno T, Schultz PG (1994) Expanding the scope of RNA catalysis. Science. [IF=7.729, Cited=65, 8009223].
- Judice JK, Gamble TR, Murphy EC, ..., Schultz PG (1993) Probing the mechanism of staphylococcal nuclease with unnatural
amino acids: kinetic and structural studies. Science. [IF=7.729, Cited=24, 8103944].
- Chung HH, Benson DR, Schultz PG (1993) Probing the structure and mechanism of Ras protein with an expanded genetic code.
Science. [IF=7.729, Cited=73, 8430333].
- Bakowski MA, Shiroodi RK, Liu R, ..., McNamara CW (2019) Discovery of short-course antiwolbachial quinazolines for
elimination of filarial worm infections. Science Translational Medicine. [IF=2.778, Cited=20, 31068442].
- Wieland SF, Vega RG, Müller R, ..., Chisari FV (2003) Searching for interferon-induced genes that inhibit hepatitis B
virus replication in transgenic mouse hepatocytes. Journal of Virology. [IF=1.075, Cited=76, 12502840].
Publication with MISSING institution:
- Ting AY, Ting A, Witte K, ..., Schultz PG (2001) Phage-display evolution of tyrosine kinases with altered nucleotide
specificity. Biopolymers. [IF=0.522, Cited=10, 11774228].
- Damoiseaux R, Schultz PG, Johnsson K (2002) Towards the generation of artificial O6-alkylguanine-DNA alkyltransferases:
in vitro selection of antibodies with reactive cysteine residues. ChemBioChem. [IF=0.691, Cited=3, 12325014].
- Chang YT, Choi G, Bae YS, ..., Ryu SH (2002) Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase.
ChemBioChem. [IF=0.691, Cited=43, 12210991].
- Chin JW, Schultz PG (2002) In vivo photocrosslinking with unnatural amino Acid mutagenesis. ChemBioChem. [IF=0.691,
Cited=85, 12404640].
- Zhang Z, Wang L, Brock A, Schultz PG (2002) The selective incorporation of alkenes into proteins in Escherichia coli.
Angewandte Chemie - International Edition. [IF=2.456, Cited=37, 12203503].
- Yu C, Henry AA, Romesberg FE, Schultz PG (2002) Polymerase recognition of unnatural base pairs. Angewandte Chemie -
International Edition. [IF=2.456, Cited=17, 12386865].
- Martin MT, Schantz AR, Schultz PG, Rees AR (1991) Characterization of the mechanism of action of a catalytic antibody.
None. [IF=None, Cited=0, 1959447].
- Nakayama GR, Schultz PG (1991) Approaches to the design of semisynthetic metal-dependent catalytic antibodies. None.
[IF=None, Cited=1, 1959454].
- Shokat KM, Shokat KM, Schultz PG, Schultz PG (1991) The generation of antibody combining sites containing catalytic
residues. None. [IF=None, Cited=0, 1959444].
- Gildersleeve J, Varvak A, Atwell S, ..., Schultz PG (2003) Development of a high-throughput screen for protein
catalysts: application to the directed evolution of antibody aldolases. Angewandte Chemie - International Edition.
[IF=2.456, Cited=2, 14679545].
- Wang L, Schultz PG (2004) Expanding the genetic code. Angewandte Chemie - International Edition. [IF=2.456, Cited=247, 15599909].
- Liu J, Wu X, Mitchell B, ..., Schultz PG (2005) A small-molecule agonist of the Wnt signaling pathway. Angewandte Chemie
- International Edition. [IF=2.456, Cited=83, 15724259].
- Warashina M, Min KH, Kuwabara T, ..., Ding S (2006) A synthetic small molecule that induces neuronal differentiation of
adult hippocampal neural progenitor cells. Angewandte Chemie - International Edition. [IF=2.456, Cited=47, 16323231].
- Deiters A, Groff D, Ryu Y, ..., Schultz PG (2006) A genetically encoded photocaged tyrosine. Angewandte Chemie -
International Edition. [IF=2.456, Cited=90, 16548032].
- Tian F, Debler EW, Millar DP, ..., Schultz PG (2006) The effects of antibodies on stilbene excited-state energetics.
Angewandte Chemie - International Edition. [IF=2.456, Cited=2, 17089439].
- Liu W, Alfonta L, Mack AV, Schultz PG (2007) Structural basis for the recognition of para-benzoyl-L-phenylalanine by
evolved aminoacyl-tRNA synthetases. Angewandte Chemie - International Edition. [IF=2.456, Cited=19, 17628477].
- Wang J, Schiller SM, Schultz PG (2007) A biosynthetic route to dehydroalanine-containing proteins. Angewandte Chemie -
International Edition. [IF=2.456, Cited=48, 17685371].
- Xie J, Liu W, Schultz PG (2007) A genetically encoded bidentate, metal-binding amino acid. Angewandte Chemie -
International Edition. [IF=2.456, Cited=63, 17893898].
- Guo J, Wang J, Anderson JC, Schultz PG (2008) Addition of an alpha-hydroxy acid to the genetic code of bacteria.
Angewandte Chemie - International Edition. [IF=2.456, Cited=37, 18069708].
- Guo J, Wang J, Lee JS, Schultz PG (2008) Site-specific incorporation of methyl- and acetyl-lysine analogues into
recombinant proteins. Angewandte Chemie - International Edition. [IF=2.456, Cited=47, 18624319].
- Brustad E, Bushey ML, Lee JW, ..., Schultz PG (2008) A genetically encoded boronate-containing amino acid. Angewandte
Chemie - International Edition. [IF=2.456, Cited=64, 18816552].
- Groff D, Thielges MC, Cellitti S, ..., Romesberg FE (2009) Efforts toward the direct experimental characterization of
enzyme microenvironments: tyrosine100 in dihydrofolate reductase. Angewandte Chemie - International Edition. [IF=2.456,
Cited=22, 19347910].
- Chen PR, Groff D, Guo J, ..., Schultz PG (2009) A facile system for encoding unnatural amino acids in mammalian cells.
Angewandte Chemie - International Edition. [IF=2.456, Cited=131, 19378306].
- Guo J, Melançon CE, Lee HS, ..., Schultz PG (2009) Evolution of amber suppressor tRNAs for efficient bacterial
production of proteins containing nonnatural amino acids. Angewandte Chemie - International Edition. [IF=2.456,
Cited=89, 19856359].
- Ai HW, Shen W, Brustad E, Schultz PG (2010) Genetically encoded alkenes in yeast. Angewandte Chemie - International
Edition. [IF=2.456, Cited=30, 20025009].
- Groff D, Wang F, Jockusch S, ..., Schultz PG (2010) A new strategy to photoactivate green fluorescent protein.
Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 20836111].
- Lyssiotis CA, Lairson LL, Boitano AE, ..., Schultz PG (2011) Chemical control of stem cell fate and developmental
potential. Angewandte Chemie - International Edition. [IF=2.456, Cited=60, 21184400].
- Gonzalez R, Lee JW, Snyder EY, Schultz PG (2011) Dorsomorphin promotes human embryonic stem cell self-renewal.
Angewandte Chemie - International Edition. [IF=2.456, Cited=9, 21384475].
- Staerk J, Lyssiotis CA, Medeiro LA, ..., Schultz PG (2011) Pan-Src family kinase inhibitors replace Sox2 during the
direct reprogramming of somatic cells. Angewandte Chemie - International Edition. [IF=2.456, Cited=28, 21547985].
- Gonzalez R, Lee JW, Schultz PG (2011) Stepwise chemically induced cardiomyocyte specification of human embryonic stem
cells. Angewandte Chemie - International Edition. [IF=2.456, Cited=37, 22191091].
- Lee JW, Hirota T, Peters EC, ..., Kay SA (2011) A small molecule modulates circadian rhythms through phosphorylation of
the period protein. Angewandte Chemie - International Edition. [IF=2.456, Cited=27, 21954091].
- Kim CH, Kang M, Kim HJ, ..., Schultz PG (2012) Site-specific incorporation of ε-N-crotonyllysine into histones.
Angewandte Chemie - International Edition. [IF=2.456, Cited=54, 22689270].
- Wang D, Wang J, Bonamy GMC, ..., Schultz PG (2012) A small molecule promotes mitochondrial fusion in mammalian cells.
Angewandte Chemie - International Edition. [IF=2.456, Cited=80, 22907892].
- Wang F, Niu W, Guo J, Schultz PG (2012) Unnatural amino acid mutagenesis of fluorescent proteins. Angewandte Chemie -
International Edition. [IF=2.456, Cited=30, 22951916].
- Chatterjee A, Xiao H, Yang PY, ..., Schultz PG (2013) A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid
mutagenesis in E. coli. Angewandte Chemie - International Edition. [IF=2.456, Cited=30, 23554007].
- Zhang Y, Wang D, de Lichtervelde L, ..., Wang F (2013) Functional antibody CDR3 fusion proteins with enhanced
pharmacological properties. Angewandte Chemie - International Edition. [IF=2.456, Cited=19, 23794517].
- Zhang Y, Goswami D, Wang D, ..., Schultz PG (2013) An antibody with a variable-region coiled-coil "knob" domain.
Angewandte Chemie - International Edition. [IF=2.456, Cited=19, 24254636].
- Xiao H, Chatterjee A, Choi Sh, ..., Schultz PG (2013) Genetic incorporation of multiple unnatural amino acids into
proteins in mammalian cells. Angewandte Chemie - International Edition. [IF=2.456, Cited=86, 24353230].
- Lu H, Zhou Q, Deshmukh V, ..., Schultz PG (2014) Targeting human C-type lectin-like molecule-1 (CLL1) with a bispecific
antibody for immunotherapy of acute myeloid leukemia. Angewandte Chemie - International Edition. [IF=2.456, Cited=40, 25056598].
- Kularatne SA, Deshmukh V, Ma J, ..., Schultz PG (2014) A CXCR4-targeted site-specific antibody-drug conjugate.
Angewandte Chemie - International Edition. [IF=2.456, Cited=32, 25213874].
- Zhang Y, Zou H, Wang Y, ..., Wang F (2014) Rational design of a humanized glucagon-like peptide-1 receptor agonist
antibody. Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 25556336].
- Moran EJ, Wilson TE, Cho CY, ..., Schultz PG (1995) Novel biopolymers for drug discovery. Biopolymers. [IF=0.522,
Cited=8, 7718743].
- Deiters A, Geierstanger BH, Schultz PG (2005) Site-specific in vivo labeling of proteins for NMR studies. ChemBioChem.
[IF=0.691, Cited=14, 15549724].
- Tsao ML, Tian F, Schultz PG (2005) Selective Staudinger modification of proteins containing p-azidophenylalanine.
ChemBioChem. [IF=0.691, Cited=52, 16317766].
- Lowery TJ, Garcia S, Chavez L, ..., Wemmer DE (2006) Optimization of xenon biosensors for detection of protein
interactions. ChemBioChem. [IF=0.691, Cited=40, 16342304].
- Lee J, Wu X, Pasca di Magliano M, ..., Schultz PG (2007) A small-molecule antagonist of the hedgehog signaling pathway.
ChemBioChem. [IF=0.691, Cited=35, 17886323].
- Tippmann EM, Liu W, Summerer D, ..., Schultz PG (2007) A genetically encoded diazirine photocrosslinker in Escherichia
coli. ChemBioChem. [IF=0.691, Cited=53, 18000916].
- Mills JH, Lee HS, Liu CC, ..., Schultz PG (2009) A genetically encoded direct sensor of antibody-antigen interactions.
ChemBioChem. [IF=0.691, Cited=12, 19672911].
- Groff D, Chen PR, Peters FB, Schultz PG (2010) A genetically encoded epsilon-N-methyl lysine in mammalian cells.
ChemBioChem. [IF=0.691, Cited=45, 20422671].
- Bouchez LC, Boitano AE, de Lichtervelde L, ..., Schultz PG (2011) Small-molecule regulators of human stem cell self-
renewal. ChemBioChem. [IF=0.691, Cited=9, 21381174].
- Ai Hw, Shen W, Sagi A, ..., Schultz PG (2011) Probing protein-protein interactions with a genetically encoded photo-
crosslinking amino acid. ChemBioChem. [IF=0.691, Cited=65, 21678540].
- Charbon G, Brustad E, Scott KA, ..., Chapman E (2011) Subcellular protein localization by using a genetically encoded
fluorescent amino acid. ChemBioChem. [IF=0.691, Cited=26, 21681882].
- Chatterjee A, Lajoie MJ, Xiao H, ..., Schultz PG (2014) A bacterial strain with a unique quadruplet codon specifying
non-native amino acids. ChemBioChem. [IF=0.691, Cited=33, 24867343].
- Sun SB, Schultz PG, Kim CH (2014) Therapeutic applications of an expanded genetic code. ChemBioChem. [IF=0.691,
Cited=27, 25044800].
- Nam Tg, Lee J, Walker JR, ..., Schultz PG (2011) Identification and characterization of small-molecule inducers of fetal
hemoglobin. ChemMedChem. [IF=0.766, Cited=4, 21416611].
- Li S, Liao J, Cutler G, ..., Ling XB (2002) Comparative analysis of human genome assemblies reveals genome-level
differences. Genomics. [IF=1.012, Cited=5, 12160725].
- Wedemayer GJ, Wang LH, Patten PA, ..., Stevens RC (1997) Crystal structures of the free and liganded form of an
esterolytic catalytic antibody. Journal of Molecular Biology. [IF=1.281, Cited=26, 9159478].
- Ulrich HD, Schultz PG (1998) Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies.
Journal of Molecular Biology. [IF=1.281, Cited=8, 9451442].
- Yang PL, Schultz PG (1999) Mutational analysis of the affinity maturation of antibody 48G7. Journal of Molecular
Biology. [IF=1.281, Cited=26, 10600377].
- Magliery TJ, Anderson JC, Schultz PG (2001) Expanding the genetic code: selection of efficient suppressors of four-base
codons and identification of "shifty" four-base codons with a library approach in Escherichia coli. Journal of Molecular
Biology. [IF=1.281, Cited=77, 11273699].
- Umanah G, Huang LY, Schultz PG, ..., Becker JM (2009) Incorporation of the unnatural amino acid p-benzoyl-L-
phenylalanine (Bpa) into a G protein-coupled receptor in its native context. Advances in Experimental Medicine and
Biology. [IF=0.945, Cited=4, 19400216].
- Ulrich HD, Moore FL, Schultz PG (1997) Germline diversity within the mouse Igk-V9 gene family. Immunogenetics.
[IF=0.672, Cited=2, 9382926].
- Liao J, Schultz PG (2003) Three sweet receptor genes are clustered in human chromosome 1. Mammalian Genome. [IF=0.583,
Cited=27, 12856281].
- Jones DH, Cellitti SE, Hao X, ..., Geierstanger BH (2009) Site-specific labeling of proteins with NMR-active unnatural
amino acids. Journal of Biomolecular NMR. [IF=0.794, Cited=40, 19669620].
- Pollack SJ, Nakayama GR, Schultz PG (1989) Design of catalytic antibodies. None. [IF=None, Cited=3, 2601630].
- Ellman J, Mendel D, Anthony-Cahill S, ..., Schultz PG (1991) Biosynthetic method for introducing unnatural amino acids
site-specifically into proteins. None. [IF=None, Cited=72, 1784180].
- Shokat KM, Shokat KM, Schultz PG, Schultz PG (1991) Catalytic antibodies. None. [IF=None, Cited=5, 1762563].
- Jacobsen JR, Schultz PG (1995) The scope of antibody catalysis. Current Opinion in Structural Biology. [IF=1.4,
Cited=4, 8749371].
- Anthony-Cahill SJ, Griffith MC, Noren CJ, ..., Schultz PG (1989) Site-specific mutagenesis with unnatural amino acids.
Trends in Biochemical Sciences. [IF=2.462, Cited=9, 2683258].
- Chang YT, Gray NS, Rosania GR, ..., Schultz PG (1999) Synthesis and application of functionally diverse
2,6,9-trisubstituted purine libraries as CDK inhibitors. None. [IF=None, Cited=108, 10375538].
- Zimmermann N, Meggers E, Schultz PG (2004) A second-generation copper(II)-mediated metallo-DNA-base pair. Bioorganic
Chemistry. [IF=1.325, Cited=27, 14700559].
- Saraf-Levy T, Santoro SW, Volpin H, ..., Carmi N (2006) Site-specific recombination of asymmetric lox sites mediated by
a heterotetrameric Cre recombinase complex. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=10, 16412655].
- Lee J, Hong J, Nam TG, ..., Schultz PG (2008) A small molecule inhibitor of alpha4 integrin-dependent cell migration.
Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=5, 18329275].
- Wu TYH, Hassig C, Wu Y, ..., Schultz PG (2004) Design, synthesis, and activity of HDAC inhibitors with a N-formyl
hydroxylamine head group. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=26, 14698179].
- Deiters A, Cropp TA, Summerer D, ..., Schultz PG (2004) Site-specific PEGylation of proteins containing unnatural amino
acids. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=109, 15501033].
- Deiters A, Schultz PG (2005) In vivo incorporation of an alkyne into proteins in Escherichia coli. Bioorganic and
Medicinal Chemistry Letters. [IF=0.704, Cited=89, 15713420].
- Zeng H, Xie J, Schultz PG (2006) Genetic introduction of a diketone-containing amino acid into proteins. Bioorganic and
Medicinal Chemistry Letters. [IF=0.704, Cited=19, 16934461].
- Brustad E, Bushey ML, Brock A, ..., Schultz PG (2008) A promiscuous aminoacyl-tRNA synthetase that incorporates
cysteine, methionine, and alanine homologs into proteins. Bioorganic and Medicinal Chemistry Letters. [IF=0.704,
Cited=29, 18845434].
- Melançon CE, Schultz PG (2009) One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetases.
Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=26, 19398201].
- Lee HS, Dimla RD, Schultz PG (2009) Protein-DNA photo-crosslinking with a genetically encoded benzophenone-containing
amino acid. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=20, 19643606].
- Charbon G, Wang J, Brustad E, ..., Chapman E (2011) Localization of GroEL determined by in vivo incorporation of a
fluorescent amino acid. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=14, 21890355].
- Young DD, Jockush S, Turro NJ, Schultz PG (2011) Synthetase polyspecificity as a tool to modulate protein function.
Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=23, 22041062].
- Day JW, Kim CH, Smider VV, Schultz PG (2013) Identification of metal ion binding peptides containing unnatural amino
acids by phage display. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=14, 23541674].
- Xie J, Schultz PG (2005) Adding amino acids to the genetic repertoire. Current Opinion in Chemical Biology. [IF=1.51,
Cited=85, 16260173].
- Kim CH, Axup JY, Schultz PG (2013) Protein conjugation with genetically encoded unnatural amino acids. Current Opinion
in Chemical Biology. [IF=1.51, Cited=125, 23664497].
- Wang F, Ekiert DC, Ahmad I, ..., Smider VV (2013) Reshaping antibody diversity. Cell. [IF=8.479, Cited=129, 23746848].
- Baldwin EP, Martin SS, Abel J, ..., Santoro SW (2003) A specificity switch in selected cre recombinase variants is
mediated by macromolecular plasticity and water. None. [IF=None, Cited=20, 14652076].
- Wu X, Walker J, Zhang J, ..., Schultz PG (2004) Purmorphamine induces osteogenesis by activation of the hedgehog
signaling pathway. None. [IF=None, Cited=140, 15380183].
- Luesch H, Wu TYH, Ren P, ..., Supek F (2005) A genome-wide overexpression screen in yeast for small-molecule target
identification. None. [IF=None, Cited=70, 15664515].
- Peters FB, Brock A, Wang J, Schultz PG (2009) Photocleavage of the polypeptide backbone by 2-nitrophenylalanine. None.
[IF=None, Cited=35, 19246005].
- Hur W, Sun Z, Jiang T, ..., Gray NS (2010) A small-molecule inducer of the antioxidant response element. None. [IF=None,
Cited=52, 20534351].
- Hutchins BM, Kazane SA, Staflin K, ..., Schultz PG (2011) Selective formation of covalent protein heterodimers with an
unnatural amino acid. None. [IF=None, Cited=36, 21439474].
- Tao H, Jin Q, Koo DI, ..., Wu X (2011) Small molecule antagonists in distinct binding modes inhibit drug-resistant
mutant of smoothened. None. [IF=None, Cited=40, 21513879].
- de Lichtervelde L, Antal CE, Boitano AE, ..., Schultz PG (2012) Euphohelioscopin A is a PKC activator capable of
inducing macrophage differentiation. None. [IF=None, Cited=2, 22921066].
- Cho CY, Koo SH, Wang Y, ..., Chanda SK (2006) Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of
hepatic insulin signaling. Cell Metabolism. [IF=4.686, Cited=37, 16679294].
- Chen S, Schultz PG, Brock A (2007) An improved system for the generation and analysis of mutant proteins containing
unnatural amino acids in Saccharomyces cerevisiae. Journal of Molecular Biology. [IF=1.281, Cited=52, 17560600].
- Young TS, Ahmad I, Yin JA, Schultz PG (2009) An enhanced system for unnatural amino acid mutagenesis in E. coli. Journal
of Molecular Biology. [IF=1.281, Cited=369, 19852970].
- Hutchins BM, Kazane SA, Staflin K, ..., Smider VV (2011) Site-specific coupling and sterically controlled formation of
multimeric antibody fab fragments with unnatural amino acids. Journal of Molecular Biology. [IF=1.281, Cited=41, 21237172].
- Shoji S, Dambacher CM, Shajani Z, ..., Schultz PG (2011) Systematic chromosomal deletion of bacterial ribosomal protein
genes. Journal of Molecular Biology. [IF=1.281, Cited=71, 21945294].
- Lowery TJ, Rubin SM, Ruiz EJ, ..., Wemmer DE (2003) Applications of laser-polarized 129Xe to biomolecular assays.
Magnetic Resonance Imaging. [IF=0.944, Cited=11, 14725931].
- Williams B, Watanabe CMH, Schultz PG, ..., Krucker T (2004) Age-related effects of Ginkgo biloba extract on synaptic
plasticity and excitability. Neurobiology of Aging. [IF=1.058, Cited=45, 15212849].
- Zhu S, Wurdak H, Wang J, ..., Schultz PG (2009) A small molecule primes embryonic stem cells for differentiation. None.
[IF=None, Cited=111, 19427291].
- Wurdak H, Zhu S, Romero A, ..., Schultz PG (2010) An RNAi screen identifies TRRAP as a regulator of brain tumor-
initiating cell differentiation. None. [IF=None, Cited=86, 20085741].
- Cropp TA, Schultz PG (2004) An expanding genetic code. Trends in Genetics. [IF=2.117, Cited=36, 15522458].
- Xie J, Schultz PG (2005) An expanding genetic code. Methods. [IF=0.927, Cited=72, 16076448].
- Yin J, Beuscher AE, Andryski SE, ..., Schultz PG (2003) Structural plasticity and the evolution of antibody affinity and
specificity. Journal of Molecular Biology. [IF=1.281, Cited=88, 12850137].
- Driggers EM, Schultz PG (1996) Catalytic antibodies. None. [IF=None, Cited=7, 8908300].
- Hogenesch JB, Ching KA, Batalov S, ..., Cooke MP (2001) A comparison of the Celera and Ensembl predicted gene sets
reveals little overlap in novel genes. Cell. [IF=8.479, Cited=113, 11534548].
- Panda S, Antoch MP, Miller BH, ..., Hogenesch JB (2002) Coordinated transcription of key pathways in the mouse by the
circadian clock. Cell. [IF=8.479, Cited=1000, 12015981].
- Gildersleeve J, Janes J, Ulrich H, ..., Schultz PG (2002) Development of a genetic selection for catalytic antibodies.
Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=1, 12039592].
- Romesberg FE, Schultz PG (1999) A mutational study of a Diels-Alderase catalytic antibody. Bioorganic and Medicinal
Chemistry Letters. [IF=0.704, Cited=5, 10406634].
- Chang YT, Schultz PG (1999) Versatile fluorescence labeling method using activated esters on solid support. Bioorganic
and Medicinal Chemistry Letters. [IF=0.704, Cited=1, 10498192].
- Ku J, Schultz PG (1994) Phage display of catalytically active staphylococcal nuclease. Bioorganic and Medicinal
Chemistry. [IF=0.86, Cited=6, 7788304].
- Pastrnak M, Schultz PG (2001) Phage selection for site-specific incorporation of unnatural amino acids into proteins in
vivo. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=10, 11553478].
- Cho CY, Liu CW, Wemmer DE, Schultz PG (1999) Cyclic and linear oligocarbamate ligands for human thrombin. Bioorganic and
Medicinal Chemistry. [IF=0.86, Cited=0, 10428389].
- Wang L, Schultz PG (2001) A general approach for the generation of orthogonal tRNAs. None. [IF=None, Cited=114, 11564556].
- Anderson JC, Magliery TJ, Schultz PG (2002) Exploring the limits of codon and anticodon size. None. [IF=None, Cited=46, 11880038].
- Watanabe CMH, Supekova L, Schultz PG (2002) Transcriptional effects of the potent enediyne anti-cancer agent
Calicheamicin gamma(I)(1). None. [IF=None, Cited=12, 11880039].
- Perez OD, Chang YT, Rosania G, ..., Schultz PG (2002) Inhibition and reversal of myogenic differentiation by purine-
based microtubule assembly inhibitors. None. [IF=None, Cited=32, 11983336].
- Supekova L, Pezacki JP, Su AI, ..., Wemmer DE (2002) Genomic effects of polyamide/DNA interactions on mRNA expression.
None. [IF=None, Cited=22, 12144926].
- Chin JW, Cropp TA, Chu S, ..., Schultz PG (2003) Progress toward an expanded eukaryotic genetic code. None. [IF=None,
Cited=52, 12837384].
- Wu TYH, Wagner KW, Bursulaya B, ..., Deveraux QL (2003) Development and characterization of nonpeptidic small molecule
inhibitors of the XIAP/caspase-3 interaction. None. [IF=None, Cited=67, 12954335].
- Cload ST, Liu DR, Liu DR, ..., Schultz PG (1996) Development of improved tRNAs for in vitro biosynthesis of proteins
containing unnatural amino acids. None. [IF=None, Cited=37, 9000011].
- Liu DR, Liu DR, Magliery TJ, ..., Schultz PG (1997) Characterization of an 'orthogonal' suppressor tRNA derived from E.
coli tRNA2(Gln). None. [IF=None, Cited=19, 9331409].
- Li JC, Nasertorabi F, Xuan W, ..., Schultz PG (2020) A Single Reactive Noncanonical Amino Acid is Able to Dramatically
Stabilize Protein Structure. ACS Chemical Biology. [IF=0.963, Cited=0, 33006884].
- Angeles TS, Smith RG, Darsley MJ, ..., Martin MT (1993) Isoabzymes: structurally and mechanistically similar catalytic
antibodies from the same immunization. Biochemistry. [IF=0.753, Cited=20, 8218291].
- Martin MT, Napper AD, Schultz PG, Rees AR (1991) Mechanistic studies of a tyrosine-dependent catalytic antibody.
Biochemistry. [IF=0.753, Cited=16, 1911763].
- Cornish VW, Kaplan MI, Veenstra DL, ..., Schultz PG (1994) Stabilizing and destabilizing effects of placing beta-
branched amino acids in protein alpha-helices. Biochemistry. [IF=0.753, Cited=20, 7918421].
- Schultz PG, Schultz PG, Au KG, ..., Walsh CT (1985) Directed mutagenesis of the redox-active disulfide in the
flavoenzyme mercuric ion reductase. Biochemistry. [IF=0.753, Cited=19, 3907703].
- Corey DR, Pei D, Schultz PG (1989) Generation of a catalytic sequence-specific hybrid DNase. Biochemistry. [IF=0.753,
Cited=12, 2605184].
- Xu R, Hanson SR, Zhang Z, ..., Wong CH (2009) Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-
O-threonine into protein in Escherichia coli. Journal of the American Chemical Society. [IF=2.573, Cited=6, 19731911].
- Sun SB, Sen S, Kim NJ, ..., Wang F (2018) Retraction of "Mutational Analysis of 48G7 Reveals that Somatic Hypermutation
Affects Both Antibody Stability and Binding Affinity". Journal of the American Chemical Society. [IF=2.573, Cited=2, 29376652].
- Shokat KM, Shokat KM, Leumann CJ, ..., Schultz PG (1989) A new strategy for the generation of catalytic antibodies.
Nature. [IF=11.591, Cited=40, 2922053].
- Bishop AC, Ubersax JA, Petsch DT, ..., Shokat KM (2000) A chemical switch for inhibitor-sensitive alleles of any protein
kinase. Nature. [IF=11.591, Cited=728, 11014197].
- Alivisatos AP, Alivisatos AP, Alivisatos AP, ..., Schultz PG (1996) Organization of 'nanocrystal molecules' using DNA.
Nature. [IF=11.591, Cited=753, 8757130].
- Ulrich HD, Mundorff E, Santarsiero BD, ..., Schultz PG (1997) The interplay between binding energy and catalysis in the
evolution of a catalytic antibody. Nature. [IF=11.591, Cited=35, 9305839].
- Rosania GR, Chang YT, Perez O, ..., Schultz PG (2000) Myoseverin, a microtubule-binding molecule with novel cellular
effects. Nature Biotechnology. [IF=8.861, Cited=102, 10700146].
- Lu T, Ting AY, Ting A, ..., Yang J (2001) Probing ion permeation and gating in a K+ channel with backbone mutations in
the selectivity filter. Nature Neuroscience. [IF=4.893, Cited=77, 11224539].
- Dubrovska A, Hartung A, Bouchez LC, ..., Schultz PG (2012) CXCR4 activation maintains a stem cell population in
tamoxifen-resistant breast cancer cells through AhR signalling. British Journal of Cancer. [IF=1.928, Cited=70, 22644306].
- Macpherson LJ, Dubin AE, Evans MJ, ..., Patapoutian A (2007) Noxious compounds activate TRPA1 ion channels through
covalent modification of cysteines. Nature. [IF=11.591, Cited=715, 17237762].
- Hannedouche S, Zhang J, Yi T, ..., Sailer AW (2011) Oxysterols direct immune cell migration via EBI2. Nature.
[IF=11.591, Cited=262, 21796212].
- Xie J, Wang L, Wu N, ..., Schultz PG (2004) The site-specific incorporation of p-iodo-L-phenylalanine into proteins for
structure determination. Nature Biotechnology. [IF=8.861, Cited=67, 15378068].
- Liu CC, Schultz PG (2006) Recombinant expression of selectively sulfated proteins in Escherichia coli. Nature
Biotechnology. [IF=8.861, Cited=86, 17072302].
- Santoro SW, Wang L, Herberich B, ..., Schultz PG (2002) An efficient system for the evolution of aminoacyl-tRNA
synthetase specificity. Nature Biotechnology. [IF=8.861, Cited=108, 12244330].
- Ding S, Schultz PG (2004) A role for chemistry in stem cell biology. Nature Biotechnology. [IF=8.861, Cited=183, 15229546].
- Jones CA, Nishiya N, London NR, ..., Li DY (2009) Slit2-Robo4 signalling promotes vascular stability by blocking Arf6
activity. Nature Cell Biology. [IF=3.908, Cited=145, 19855388].
- Lemke EA, Summerer D, Geierstanger BH, ..., Schultz PG (2007) Control of protein phosphorylation with a genetically
encoded photocaged amino acid. Nature Chemical Biology. [IF=2.623, Cited=124, 17965709].
- Kato N, Sakata T, Breton G, ..., Winzeler EA (2008) Gene expression signatures and small-molecule compounds link a
protein kinase to Plasmodium falciparum motility. Nature Chemical Biology. [IF=2.623, Cited=138, 18454143].
- Luesch H, Chanda SK, Raya RM, ..., Schultz PG (2006) A functional genomics approach to the mode of action of apratoxin
A. Nature Chemical Biology. [IF=2.623, Cited=73, 16474387].
- Liu W, Brock A, Chen S, ..., Schultz PG (2007) Genetic incorporation of unnatural amino acids into proteins in mammalian
cells. Nature Methods. [IF=10.009, Cited=204, 17322890].
- Ryu Y, Schultz PG (2006) Efficient incorporation of unnatural amino acids into proteins in Escherichia coli. Nature
Methods. [IF=10.009, Cited=173, 16554830].
- Liu CC, Cellitti SE, Geierstanger BH, Schultz PG (2009) Efficient expression of tyrosine-sulfated proteins in E. coli
using an expanded genetic code. None. [IF=None, Cited=29, 20010929].
- Xie J, Schultz PG (2006) A chemical toolkit for proteins--an expanded genetic code. Nature Reviews Molecular Cell
Biology. [IF=19.213, Cited=195, 16926858].
- Esaki M, Kanamori T, Nishikawa Si, ..., Endo T (2003) Tom40 protein import channel binds to non-native proteins and
prevents their aggregation. None. [IF=None, Cited=29, 14595396].
- Schlieker C, Weibezahn J, Patzelt H, ..., Mogk A (2004) Substrate recognition by the AAA+ chaperone ClpB. Nature
Structural and Molecular Biology. [IF=2.542, Cited=164, 15208691].
- Wang L, Schultz PG (2002) Expanding the genetic code. Chemical Communications. [IF=0.902, Cited=68, 12120285].
- Ai HW, Lee JW, Schultz PG (2010) A method to site-specifically introduce methyllysine into proteins in E. coli. Chemical
Communications. [IF=0.902, Cited=51, 20571694].
- Schultz PG, Schultz PG, Dervan PB, Dervan PB (1983) Sequence-specific double-strand cleavage of DNA by penta-N-
methylpyrrolecarboxamide-EDTA X Fe(II). Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=31, 6417654].
- Brooks EE, Gray NS, Joly A, ..., Shiffman D (1997) CVT-313, a specific and potent inhibitor of CDK2 that prevents
neointimal proliferation. Journal of Biological Chemistry. [IF=1.122, Cited=77, 9360999].
- Johnsson K, Froland WA, Schultz PG (1997) Overexpression, purification, and characterization of the catalase-peroxidase
KatG from Mycobacterium tuberculosis. Journal of Biological Chemistry. [IF=1.122, Cited=64, 9006925].
- Trisler K, Looger LL, Sharma V, ..., Smider VV (2007) A metalloantibody that irreversibly binds a protein antigen.
Journal of Biological Chemistry. [IF=1.122, Cited=6, 17617633].
- Young TS, Schultz PG (2010) Beyond the canonical 20 amino acids: expanding the genetic lexicon. Journal of Biological
Chemistry. [IF=1.122, Cited=161, 20147747].
- Li S, Cutler G, Liu JJ, ..., Ling XB (2003) A comparative analysis of HGSC and Celera human genome assemblies and gene
sets. Bioinformatics. [IF=1.954, Cited=5, 12967954].
- Robertson SA, Noren CJ, Anthony-Cahill SJ, ..., Schultz PG (1989) The use of 5'-phospho-2
deoxyribocytidylylriboadenosine as a facile route to chemical aminoacylation of tRNA. Nucleic Acids Research. [IF=4.663,
Cited=63, 2602139].
- Noren CJ, Anthony-Cahill SJ, Suich DJ, ..., Schultz PG (1990) In vitro suppression of an amber mutation by a chemically
aminoacylated transfer RNA prepared by runoff transcription. Nucleic Acids Research. [IF=4.663, Cited=39, 2308838].
- Berger M, Wu Y, Ogawa AK, ..., Romesberg FE (2000) Universal bases for hybridization, replication and chain termination.
Nucleic Acids Research. [IF=4.663, Cited=30, 10908353].
- Santoro SW, Anderson JC, Lakshman V, Schultz PG (2003) An archaebacteria-derived glutamyl-tRNA synthetase and tRNA pair
for unnatural amino acid mutagenesis of proteins in Escherichia coli. Nucleic Acids Research. [IF=4.663, Cited=39, 14627803].
- Scanlon TS, Schultz PG (1991) Recent advances in catalytic antibodies. Philosophical Transactions of the Royal Society
B: Biological Sciences. [IF=1.629, Cited=1, 1678534].
- Riva L, Yuan S, Yin X, ..., Chanda SK (2020) A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals. None.
[IF=None, Cited=7, 32511357].
- Gupta AK, Eliasen AM, Andahazy W, ..., McNamara CW (2024) A Prodrug Strategy to Reposition Atovaquone as a Long-Acting
Injectable for Malaria Chemoprotection. None. [IF=None, Cited=0, 38979188].
- Gupta AK, Pedroarena J, Nazarian A, ..., McNamara CW (2024) Identification of mCMQ069, a novel antimalarial with
potential for a single-dose cure and/or 28-day chemoprevention. None. [IF=None, Cited=0, 39005341].
- Pollack SJ, Schultz PG (1987) Antibody catalysis by transition state stabilization. Cold Spring Harbor Symposia on
Quantitative Biology. [IF=0.889, Cited=5, 3454301].
- Zhang Y, Wang L, Schultz PG, Wilson IA (2005) Crystal structures of apo wild-type M. jannaschii tyrosyl-tRNA synthetase
(TyrRS) and an engineered TyrRS specific for O-methyl-L-tyrosine. Protein Science. [IF=1.97, Cited=44, 15840835].
- Lerner RA, Benkovic SJ, Schultz PG (1991) At the crossroads of chemistry and immunology: catalytic antibodies. Science.
[IF=7.729, Cited=229, 2024118].
- Sagan SM, Rouleau Y, Leggiadro C, ..., Pezacki JP (2006) The influence of cholesterol and lipid metabolism on host cell
structure and hepatitis C virus replication. Biochemistry and Cell Biology. [IF=0.589, Cited=58, 16462891].
- Mendel D, Cornish VW, Schultz PG (1995) Site-directed mutagenesis with an expanded genetic code. None. [IF=None,
Cited=81, 7663123].
- Shokat KM, Shokat KM, Schultz PG, Schultz PG (1990) Catalytic antibodies. Annual Review of Immunology. [IF=5.497,
Cited=21, 2188666].
- Berezhna SY, Supekova L, Sever MJ, ..., Deniz AA (2011) Dual regulation of hepatitis C viral RNA by cellular RNAi
requires partitioning of Ago2 to lipid droplets and P-bodies. RNA. [IF=0.956, Cited=18, 21868483].
- Hirota T, Lee JW, Lewis WG, ..., Kay SA (2010) High-throughput chemical screen identifies a novel potent modulator of
cellular circadian rhythms and reveals CKIα as a clock regulatory kinase. PLoS Biology. [IF=2.285, Cited=140, 21179498].
- Wang F, Robbins S, Guo J, ..., Schultz PG (2010) Genetic incorporation of unnatural amino acids into proteins in
Mycobacterium tuberculosis. PLoS ONE. [IF=1.253, Cited=36, 20179771].
- Dubrovska A, Elliott J, Salamone RJ, ..., Schultz PG (2012) CXCR4 expression in prostate cancer progenitor cells. PLoS
ONE. [IF=1.253, Cited=97, 22359577].
- Thorson JS, Cornish VW, Barrett JE, ..., Schultz PG (1998) A biosynthetic approach for the incorporation of unnatural
amino acids into proteins. Methods in Molecular Biology. [IF=0.413, Cited=9, 9770661].
- Santoro SW, Schultz PG (2003) Directed evolution of the substrate specificities of a site-specific recombinase and an
aminoacyl-tRNA synthetase using fluorescence-activated cell sorting (FACS). Methods in Molecular Biology. [IF=0.413,
Cited=5, 12824591].
- Ding S, Schultz PG (2005) Small molecules and future regenerative medicine. Current Topics in Medicinal Chemistry.
[IF=0.7, Cited=30, 15892681].
- Ulrich HD, Driggers EM, Schultz PG (1996) Antibody catalysis of pericyclic reactions. None. [IF=None, Cited=4, 8639375].
- Martin AB, Schultz PG (1999) Opportunities at the interface of chemistry and biology. Trends in Cell Biology. [IF=3.592,
Cited=0, 10611676].
- Su AI, Welsh JB, Sapinoso LM, ..., Hampton GM (2001) Molecular classification of human carcinomas by use of gene
expression signatures. Cancer Research. [IF=1.624, Cited=0, 11606367].
- Wignall SM, Gray NS, Chang YT, ..., Heald R (2004) Identification of a novel protein regulating microtubule stability
through a chemical approach. None. [IF=None, Cited=0, 15113003].
- Corey DR, Schultz PG (1989) Introduction of a metal-dependent regulatory switch into an enzyme. Journal of Biological
Chemistry. [IF=1.122, Cited=0, 2917969].