Nicolaou, K C
Publication with MATCHING institution:
- Nicolaou KC (2014) Advancing the drug discovery and development process. Angewandte Chemie - International Edition.
[IF=2.456, Cited=34, 25045053].
- Nicolaou KC, Heretsch P, ElMarrouni A, ..., Prabhu KS (2014) Total synthesis of Δ¹²-prostaglandin J₃, a highly potent
and selective antileukemic agent. Angewandte Chemie - International Edition. [IF=2.456, Cited=10, 25098181].
- Nicolaou KC, Shi L, Lu M, ..., Lamani M (2014) Total synthesis of myceliothermophins C, D, and E. Angewandte Chemie -
International Edition. [IF=2.456, Cited=6, 25163463].
- Nicolaou KC, Cai Q, Qin B, ..., Heretsch P (2015) Total synthesis of trioxacarcin DC-45-A2. Angewandte Chemie -
International Edition. [IF=2.456, Cited=7, 25583408].
- Nicolaou KC, Shah AA, Korman H, ..., Theodorakis EA (2015) Total Synthesis and Structural Revision of Antibiotic
CJ-16,264. Angewandte Chemie - International Edition. [IF=2.456, Cited=13, 26096055].
- Nicolaou KC, Lu M, Chen P, Shah AA (2015) Practical Synthesis of p- and o-Amino- and Methoxyphenolic Anthraquinones.
Angewandte Chemie - International Edition. [IF=2.456, Cited=1, 26332286].
- Nicolaou KC, Rigol S (2019) The Role of Organic Synthesis in the Emergence and Development of Antibody-Drug Conjugates
as Targeted Cancer Therapies. Angewandte Chemie - International Edition. [IF=2.456, Cited=28, 31012193].
- Nicolaou KC, Pulukuri KK, Yu R, ..., ElMarrouni A (2016) Total Synthesis of Δ(12) -Prostaglandin J3 : Evolution of
Synthetic Strategies to a Streamlined Process. Chemistry - A European Journal. [IF=0.899, Cited=5, 27187634].
- He Y, Agarwal PK, Kiran INC, ..., Nicolaou KC (2016) Efficient Synthesis of Dimeric Oxazoles, Piperidines and
Tetrahydroisoquinolines from N-Substituted 2-Oxazolones. Chemistry - A European Journal. [IF=0.899, Cited=0, 27113382].
- Nicolaou KC, Rhoades D, Wang Y, ..., Hamel E (2015) Synthesis and Biological Evaluation of Novel Epothilone B Side Chain
Analogues. ChemMedChem. [IF=0.766, Cited=2, 26447977].
- Nicolaou KC, Vourloumis D, Totokotsopoulos S, ..., Stepan AF (2015) Synthesis and Biopharmaceutical Evaluation of
Imatinib Analogues Featuring Unusual Structural Motifs. ChemMedChem. [IF=0.766, Cited=27, 26585829].
- Rodríguez LP, Vilariño N, Louzao MC, ..., Botana LM (2013) Microsphere-based immunoassay for the detection of
azaspiracids. Analytical Biochemistry. [IF=0.706, Cited=6, 24215909].
- Nicolaou KC (2014) The chemistry-biology-medicine continuum and the drug discovery and development process in academia.
None. [IF=None, Cited=7, 25237851].
- Nicolaou KC, Rigol S (2018) Total Synthesis in Search of Potent Antibody-Drug Conjugate Payloads. From the Fundamentals
to the Translational. Accounts of Chemical Research. [IF=3.533, Cited=12, 30575399].
- Nicolaou KC, Shelke YG, Dherange BD, ..., Gavrilyuk J (2020) Design, Synthesis, and Biological Investigation of
Epothilone B Analogues Featuring Lactone, Lactam, and Carbocyclic Macrocycles, Epoxide, Aziridine, and
1,1-Difluorocyclopropane and Other Fluorine Residues. Journal of Organic Chemistry. [IF=0.885, Cited=4, 32065746].
- Nicolaou KC, Rekula SR, Kumar SM, ..., Gavrilyuk J (2021) Design, Synthesis, and Biological Investigation of
Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural
Motifs. Journal of Organic Chemistry. [IF=0.885, Cited=2, 33417458].
- Nicolaou KC, Pan S, Pulukuri KK, ..., Gavrilyuk J (2021) Design, Synthesis, and Biological Evaluation of Tubulysin
Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-
Tubulin Binding Derived from X-ray Crystallographic Analysis. Journal of Organic Chemistry. [IF=0.885, Cited=2, 33544599].
- Nicolaou KC, Buchman M, Bellavance G, ..., Pulukuri KK (2018) Syntheses of Cyclopropyl Analogues of Disorazoles
A1 and B1 and Their Thiazole Counterparts. Journal of Organic Chemistry. [IF=0.885, Cited=4, 30277774].
- Nicolaou KC, Pulukuri KK, Rigol S, ..., Gavrilyuk J (2018) Short Total Synthesis of Δ12-Prostaglandin
J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic
Δ12-Prostaglandin J2 Analogues. Journal of Organic Chemistry. [IF=0.885, Cited=3, 30557504].
- Beabout K, McCurry MD, Mehta H, ..., Shamoo Y (2017) Experimental Evolution of Diverse Strains as a Method for the
Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics. ACS Infectious Diseases.
[IF=0.991, Cited=5, 28942642].
- Nicolaou KC, Hale CRH, Nilewski C, ..., Shamoo Y (2014) Total synthesis of viridicatumtoxin B and analogues thereof:
strategy evolution, structural revision, and biological evaluation. Journal of the American Chemical Society. [IF=2.573,
Cited=19, 25317739].
- Nicolaou KC, Heretsch P, Nakamura T, ..., Konoki K (2014) Synthesis and biological evaluation of QRSTUVWXYZA' domains of
maitotoxin. Journal of the American Chemical Society. [IF=2.573, Cited=10, 25374117].
- Nicolaou KC, Li R, Chen Q, ..., Gavrilyuk J (2020) Synthesis and Biological Evaluation of Shishijimicin A-Type Linker-
Drugs and Antibody-Drug Conjugates. Journal of the American Chemical Society. [IF=2.573, Cited=3, 32662641].
- Nicolaou KC, Krieger J, Murhade GM, ..., Gavrilyuk J (2020) Streamlined Symmetrical Total Synthesis of Disorazole
B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues. Journal of the American
Chemical Society. [IF=2.573, Cited=2, 32852944].
- Nicolaou KC, Chen Q, Li R, ..., Tsuchikama K (2020) Total Synthesis of the Monomeric Unit of Lomaiviticin A. Journal of
the American Chemical Society. [IF=2.573, Cited=8, 33186022].
- Nicolaou KC, Pan S, Shelke Y, ..., Rigol S (2021) A Reverse Approach to the Total Synthesis of Halichondrin B. Journal
of the American Chemical Society. [IF=2.573, Cited=5, 34105959].
- Nicolaou KC, Pan S, Shelke Y, ..., Rigol S (2021) A Highly Convergent Total Synthesis of Norhalichondrin B. Journal of
the American Chemical Society. [IF=2.573, Cited=3, 34851106].
- Nicolaou KC, Yu R, Lu Z, Alvarez FG (2022) Total Synthesis of Gukulenin B via Sequential Tropolone Functionalizations.
Journal of the American Chemical Society. [IF=2.573, Cited=2, 35275627].
- Nicolaou KC, Lu Z, Li R, ..., Sohn Ti (2015) Total Synthesis of Shishijimicin A. Journal of the American Chemical
Society. [IF=2.573, Cited=9, 26133230].
- Nicolaou KC, Yin J, Mandal D, ..., Vourloumis D (2016) Total Synthesis and Biological Evaluation of Natural and Designed
Tubulysins. Journal of the American Chemical Society. [IF=2.573, Cited=21, 26829208].
- Nicolaou KC, Cai Q, Sun H, ..., Zhu S (2016) Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7″-epi-C and Full
Structural Assignment of Trioxacarcin C. Journal of the American Chemical Society. [IF=2.573, Cited=14, 26910506].
- Nicolaou KC, Pulukuri KK, Rigol S, ..., Gavrilyuk J (2016) Synthesis and Biological Investigation of Δ(12)-Prostaglandin
J3 (Δ(12)-PGJ3) Analogues and Related Compounds. Journal of the American Chemical Society. [IF=2.573, Cited=8, 27171618].
- Nicolaou KC, Wang Y, Lu M, ..., Pitsinos EN (2016) Streamlined Total Synthesis of Uncialamycin and Its Application to
the Synthesis of Designed Analogues for Biological Investigations. Journal of the American Chemical Society. [IF=2.573,
Cited=17, 27266267].
- Nicolaou KC, Rhoades D, Lamani M, ..., Kumar SM (2016) Total Synthesis of Thailanstatin A. Journal of the American
Chemical Society. [IF=2.573, Cited=12, 27266914].
- Nicolaou KC, Liu G, Beabout K, ..., Shamoo Y (2017) Asymmetric Alkylation of Anthrones, Enantioselective Total Synthesis
of (-)- and (+)-Viridicatumtoxins B and Analogues Thereof: Absolute Configuration and Potent Antibacterial Agents.
Journal of the American Chemical Society. [IF=2.573, Cited=6, 28256128].
- Nicolaou KC, Rhoades D, Wang Y, ..., Gavrilyuk J (2017) 12,13-Aziridinyl Epothilones. Stereoselective Synthesis of
Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological
Evaluation of Potent Antitumor Agents. Journal of the American Chemical Society. [IF=2.573, Cited=7, 28513142].
- Nicolaou KC, Pulukuri KK, Rigol S, ..., Shamoo Y (2017) Enantioselective Total Synthesis of Antibiotic CJ-16,264,
Synthesis and Biological Evaluation of Designed Analogues, and Discovery of Highly Potent and Simpler Antibacterial
Agents. Journal of the American Chemical Society. [IF=2.573, Cited=3, 29064688].
- Nicolaou KC, Chen P, Zhu S, ..., Gavrilyuk J (2017) Streamlined Total Synthesis of Trioxacarcins and Its Application to
the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent
Trioxacarcin Analogues. Journal of the American Chemical Society. [IF=2.573, Cited=5, 29052423].
- Nicolaou KC, Bellavance G, Buchman M, Pulukuri KK (2017) Total Syntheses of Disorazoles A₁ and B₁ and Full Structural
Elucidation of Disorazole B₁. Journal of the American Chemical Society. [IF=2.573, Cited=7, 29064682].
- Nicolaou KC, Erande RD, Yin J, ..., Gavrilyuk J (2018) Improved Total Synthesis of Tubulysins and Design, Synthesis, and
Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for
Antibody-Drug Conjugates. Journal of the American Chemical Society. [IF=2.573, Cited=10, 29381062].
- Nicolaou KC, Li R, Lu Z, ..., Alemany LB (2018) Total Synthesis and Full Structural Assignment of Namenamicin. Journal
of the American Chemical Society. [IF=2.573, Cited=3, 29932325].
- Nicolaou KC, Rhoades D, Kumar SM (2018) Total Syntheses of Thailanstatins A-C, Spliceostatin D, and Analogues Thereof.
Stereodivergent Synthesis of Tetrasubstituted Dihydro- and Tetrahydropyrans and Design, Synthesis, Biological
Evaluation, and Discovery of Potent Antitumor Agents. Journal of the American Chemical Society. [IF=2.573, Cited=16, 29943984].
- Zhang H, Li R, Ba S, ..., Nicolaou KC (2019) DNA Binding and Cleavage Modes of Shishijimicin A. Journal of the American
Chemical Society. [IF=2.573, Cited=5, 31050893].
- Nicolaou KC, Das D, Lu Y, ..., Gavrilyuk J (2020) Total Synthesis and Biological Evaluation of Tiancimycins A and B,
Yangpumicin A, and Related Anthraquinone-Fused Enediyne Antitumor Antibiotics. Journal of the American Chemical Society.
[IF=2.573, Cited=12, 31976660].
- Nicolaou KC, Rigol S (2017) A brief history of antibiotics and select advances in their synthesis. Journal of
Antibiotics. [IF=0.805, Cited=54, 28676714].
- Nicolaou KC, Rigol S (2020) Perspectives from nearly five decades of total synthesis of natural products and their
analogues for biology and medicine. Natural Product Reports. [IF=3.292, Cited=12, 32319494].
- Nicolaou KC, Rigol S, Pitsinos EN, ..., Gavrilyuk J (2021) Uncialamycin-based antibody-drug conjugates: Unique enediyne
ADCs exhibiting bystander killing effect. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=11, 34155147].
- Nicolaou KC, Pan S, Shelke Y, ..., Ye Q (2022) A unified strategy for the total syntheses of eribulin and a macrolactam
analogue of halichondrin B. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=1, 35930662].
- Nicolaou KC (2014) Organic synthesis: the art and science of replicating the molecules of living nature and creating
others like them in the laboratory. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences.
[IF=1.382, Cited=19, 24611027].
- Savva CG, Totokotsopoulos S, Nicolaou KC, ..., Constantinou AI (2016) Selective activation of TNFR1 and NF-κB inhibition
by a novel biyouyanagin analogue promotes apoptosis in acute leukemia cells. BMC Cancer. [IF=1.166, Cited=7, 27098354].
- Cheng C, Liu Y, Balasis ME, ..., Li R (2014) Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L)
binding to Bim. Marine Drugs. [IF=1.253, Cited=7, 24608970].
- Cheng C, Liu Y, Balasis ME, ..., Li R (2014) Marinopyrrole derivatives with sulfide spacers as selective disruptors of
Mcl-1 binding to pro-apoptotic protein Bim. Marine Drugs. [IF=1.253, Cited=5, 25076060].
Publication with MISMATCHING institution:
- Nicolaou KC, Hepworth D (1998) Concise and Efficient Total Syntheses of Alkannin and Shikonin. Angewandte Chemie -
International Edition. [IF=2.456, Cited=5, 29711400].
- Nicolaou KC, Kim S, Pfefferkorn J, ..., Li T (1998) Synthesis and Biological Activity of Sarcodictyins. Angewandte
Chemie - International Edition. [IF=2.456, Cited=9, 29710898].
- Nicolaou KC, Watanabe N, Li J, ..., Winssinger N (1998) Solid-Phase Synthesis of Oligosaccharides: Construction of a
Dodecasaccharide. Angewandte Chemie - International Edition. [IF=2.456, Cited=14, 29710918].
- Nicolaou KC, Roschangar F, Vourloumis D (1998) Chemical Biology of Epothilones. Angewandte Chemie - International
Edition. [IF=2.456, Cited=45, 29711063].
- Nicolaou KC, Winssinger N, Pastor J, Murphy F (1998) Solid-Phase Synthesis of Macrocyclic Systems by a Cyclorelease
Strategy: Application of the Stille Coupling to a Synthesis of (S)-Zearalenone. Angewandte Chemie - International
Edition. [IF=2.456, Cited=8, 29711345].
- Nicolaou KC, Natarajan S, Li H, ..., Takayanagi M (1998) Total Synthesis of Vancomycin Aglycon-Part 1: Synthesis of
Amino Acids 4-7 and Construction of the AB-COD Ring Skeleton. Angewandte Chemie - International Edition. [IF=2.456,
Cited=29, 29711605].
- Nicolaou KC, Jain NF, Natarajan S, ..., Bando T (1998) Total Synthesis of Vancomycin Aglycon-Part 2: Synthesis of Amino
Acids 1-3 and Construction of the AB-COD-DOE Ring Skeleton. Angewandte Chemie - International Edition. [IF=2.456,
Cited=23, 29711613].
- Nicolaou KC, Takayanagi M, Jain NF, ..., Ramanjulu JM (1998) Total Synthesis of Vancomycin Aglycon-Part 3: Final Stages.
Angewandte Chemie - International Edition. [IF=2.456, Cited=26, 29711623].
- Papageorgiou VP, Assimopoulou AN, Couladouros EA, ..., Nicolaou KC (1999) The Chemistry and Biology of Alkannin,
Shikonin, and Related Naphthazarin Natural Products. Angewandte Chemie - International Edition. [IF=2.456, Cited=137, 29711637].
- Nicolaou KC, Jautelat R, He Y, ..., Zhong YL (1999) A Novel Route to the Fused Maleic Anhydride Moiety of CP Molecules.
Angewandte Chemie - International Edition. [IF=2.456, Cited=2, 29711784].
- Nicolaou KC, Zhong YL, Choi HS, ..., Fong KC (1999) Total Synthesis of the CP Molecules CP-263,114 and CP-225,917- Part
1: Synthesis of Key Intermediates and Intelligence Gathering. Angewandte Chemie - International Edition. [IF=2.456,
Cited=15, 29710978].
- Nicolaou KC, Zhong YL, Fong KC, ..., Choi HS (1999) Total Synthesis of the CP Molecules CP-225,917 and CP-263,114- Part
2: Evolution of the Final Strategy. Angewandte Chemie - International Edition. [IF=2.456, Cited=9, 29710974].
- Nicolaou KC, Boddy C, Bräse S, Winssinger N (1999) Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics.
Angewandte Chemie - International Edition. [IF=2.456, Cited=204, 10425471].
- Nicolaou KC, Rodríguez R, Fylaktakidou K, ..., Mitchell H (1999) Total Synthesis of Everninomicin 13,384-1-Part 2:
Synthesis of the FGHA(2) Fragment. Angewandte Chemie - International Edition. [IF=2.456, Cited=7, 10602189].
- Nicolaou KC, Mitchell H, Rodríguez R, ..., Suzuki H (1999) Total Synthesis of Everninomicin 13,384-1-Part 3: Synthesis
of the DE Fragment and Completion of the Total Synthesis. Angewandte Chemie - International Edition. [IF=2.456,
Cited=7, 10602190].
- Nicolaou KC, Simonsen K, Vassilikogiannakis G, ..., Couladouros E (1999) Biomimetic Explorations Towards the
Bisorbicillinoids: Total Synthesis of Bisorbicillinol, Bisorbibutenolide, and Trichodimerol. Angewandte Chemie -
International Edition. [IF=2.456, Cited=28, 10602241].
- Nicolaou KC, Zhong Y, Baran P (2000) New Synthetic Technology for the Rapid Construction of Novel Heterocycles-Part 2.
The Reaction of IBX with Anilides and Related Compounds. Angewandte Chemie - International Edition. [IF=2.456,
Cited=30, 10671279].
- Nicolaou KC, Winssinger N, Hughes R, ..., Cho S (2000) New Selenium-Based Safety-Catch Linkers: Solid-Phase
Semisynthesis of Vancomycin We thank Drs. D. H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric
assistance, respectively. This work was financially supported by the National Institutes of Health (USA), The Skaggs
Institute for Chemical Biology, a fellowship from the George Hewitt Foundation (N. W.), and grants from Schering Plough,
Pfizer, Glaxo, Merck, Hoffmann-La Roche, DuPont, and Abbott Laboratories. Angewandte Chemie - International Edition.
[IF=2.456, Cited=11, 10760929].
- Nicolaou KC, Mitchell H, Fylaktakidou K, ..., Rodríguez R (2000) 1,2-Seleno Migrations in Carbohydrate Chemistry:
Solution and Solid-Phase Synthesis of 2-Deoxy Glycosides, Orthoesters, and Allyl Orthoesters We thank Drs. D. H. Huang
and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. We gratefully thank Nicolas
Winssinger for helpful discussions and preparation of the selenium bromide resin. This work was financially supported by
the Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), postdoctoral fellowships from
M.E.C., Spain (R.M.R., Fullbright), the Japan Society for the Promotion of Science (H.S.), the George Hewitt Foundation
(K.C.F.), and grants from Schering Plough, Pfizer, Glaxo, Merck, Hoffmann - La Roche, DuPont, Abbott Laboratories, and
Boehringer - Ingelheim. Angewandte Chemie - International Edition. [IF=2.456, Cited=11, 10760930].
- Nicolaou KC, Jung J, Yoon W, ..., Baran P (2000) The Absolute Configuration and Asymmetric Total Synthesis of the CP
Molecules (CP-263,114 and CP-225,917, Phomoidrides B and A) We thank Drs. D. H. Huang, G. Siuzdak, and R. Chadha for
assistance with NMR spectroscopy, mass spectrometry, and X-ray crystallography, respectively. This work was financially
supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, doctoral fellowships
from the National Science Foundation (P.S.B.) and Boehringer Ingelheim (Y.H.), and grants from Array Biopharma,
Boehringer Ingelheim, Schering Plough, Pfizer, Glaxo, Merck, Hoffmann-La Roche, DuPont, and Abbott Laboratories.
Angewandte Chemie - International Edition. [IF=2.456, Cited=11, 10934377].
- Nicolaou KC, Pfefferkorn JA (2001) Solid phase synthesis of complex natural products and libraries thereof. Biopolymers.
[IF=0.522, Cited=10, 11774224].
- Nicolaou KC, Namoto K, Li J, ..., Giannakakou P (2001) Synthesis and biological evaluation of 12,13-cyclopropyl and
12,13-cyclobutyl epothilones. ChemBioChem. [IF=0.691, Cited=8, 11828429].
- Nicolaou KC, Roecker AJ, Barluenga S, ..., Cao GQ (2001) Discovery of novel antibacterial agents active against
methicillin-resistant Staphylococcus aureus from combinatorial benzopyran libraries. ChemBioChem. [IF=0.691, Cited=12, 11828478].
- Nicolaou KC, Hepworth D, King NP, ..., Winssinger N (2000) Total synthesis of 16-desmethylepothilone B, epothilone B10,
epothilone F, and related side chain modified epothilone B analogues. Chemistry - A European Journal. [IF=0.899,
Cited=13, 10985727].
- Nicolaou KC, Rodríguez RM, Mitchell HJ, ..., van Delft FL (2000) Total synthesis of everninomicin 13,384-1--Part 1:
retrosynthetic analysis and synthesis of the A1B(A)C fragment. Chemistry - A European Journal. [IF=0.899, Cited=21, 11002992].
- Nicolaou KC, Mitchell HJ, Fylaktakidou KC, ..., Suzuki H (2000) Total synthesis of everninomicin 13,384-1--Part 2:
synthesis of the FGHA2 fragment. Chemistry - A European Journal. [IF=0.899, Cited=11, 11002993].
- Nicolaou KC, Mitchell HJ, Rodríguez RM, ..., Conley SR (2000) Total synthesis of everninomicin 13,384-1--Part 3:
synthesis of the DE fragment and completion of the total synthesis. Chemistry - A European Journal. [IF=0.899, Cited=8, 11002994].
- Nicolaou KC, Fylaktakidou KC, Mitchell HJ, ..., Jin Z (2000) Total synthesis of everninomicin 13,384-1--Part 4:
explorations of methodology; stereocontrolled synthesis of 1,1'-disaccharides, 1,2-seleno migrations in carbohydrates,
and solution- and solid-phase synthesis of 2-deoxy glycosides and orthoesters. Chemistry - A European Journal.
[IF=0.899, Cited=8, 11002995].
- Nicolaou KC, Cho SY, Hughes R, ..., Endermann R (2001) Solid- and solution-phase synthesis of vancomycin and vancomycin
analogues with activity against vancomycin-resistant bacteria. Chemistry - A European Journal. [IF=0.899, Cited=31, 11575782].
- Nicolaou KC, Hughes R, Cho SY, ..., Endermann R (2001) Synthesis and biological evaluation of vancomycin dimers with
potent activity against vancomycin-resistant bacteria: target-accelerated combinatorial synthesis. Chemistry - A
European Journal. [IF=0.899, Cited=51, 11575783].
- Nicolaou KC, Hughes R, Pfefferkorn JA, ..., Roecker AJ (2001) Combinatorial synthesis through disulfide exchange:
discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus
(MRSA). Chemistry - A European Journal. [IF=0.899, Cited=33, 11686609].
- Nicolaou KC, Hughes R, Pfefferkorn JA, Barluenga S (2001) Optimization and mechanistic studies of psammaplin A type
antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA). Chemistry - A European Journal.
[IF=0.899, Cited=12, 11686610].
- Nicolaou KC, Vassilikogiannakis G, Mägerlein W, Kranich R (2001) Total synthesis of colombiasin A and determination of
its absolute configuration. Chemistry - A European Journal. [IF=0.899, Cited=22, 11822436].
- Nicolaou KC, Koumbis A, Snyder S, Simonsen K (2000) Novel Reactions Initiated by Titanocene Methylidenes: Deoxygenation
of Sulfoxides, N-Oxides, and Selenoxides We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass
spectroscopic assistance, respectively. Financial support for this work was provided by The Skaggs Institute for
Chemical Biology, the National Institutes of Health (USA), fellowships from the National Science Foundation (S.A.S.) and
the Alfred Benzons Foundation (K.B.S.), and grants from Abbott, Amgen, Boehringer-Ingelheim, GlaxoWellcome, Hoffmann-
LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456,
Cited=6, 10941126].
- Nicolaou KC, Snyder S, Simonsen K, Koumbis A (2000) Model Studies towards Diazonamide A: Synthesis of the Heterocyclic
Core We thank Dr. D. H. Huang, Dr. G. Suizdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray
crystallographic assistance, respectively. We also thank Professor R. H. Grubbs for a generous gift of catalyst 30.
Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of
Health (USA), a predoctoral fellowship from the National Science Foundation (S.A.S.), postdoctoral fellowships from the
Alfred Benzons Foundation and the Danish Natural Science Research Council (K.B.S.), and grants from Abbott, Amgen,
ArrayBiopharma, Boehringer-Ingelheim, GlaxoWellcome, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering
Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=9, 11091394].
- Nicolaou KC, Hughes R, Cho SY, ..., Endermann R (2000) Target-Accelerated Combinatorial Synthesis and Discovery of
Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria. Angewandte Chemie - International Edition.
[IF=2.456, Cited=40, 29711708].
- Nicolaou KC, Kranich R, Zhong YL, ..., Zou N (2001) Mechanistic Studies of Periodinane-Mediated Reactions of Anilides
and Related Systems. Angewandte Chemie - International Edition. [IF=2.456, Cited=2, 29711956].
- Nicolaou KC, Sugita K, Zhong YL (2001) New Synthetic Technology for the Construction of N-Containing Quinones and
Derivatives Thereof: Total Synthesis of Epoxyquinomycin B. Angewandte Chemie - International Edition. [IF=2.456,
Cited=1, 29711950].
- Nicolaou KC, Zhong YL, Sugita K (2001) Rapid Access to Complex Molecular Architectures via o-Azaquinones. Angewandte
Chemie - International Edition. [IF=2.456, Cited=0, 29712189].
- Nicolaou KC, Vassilikogiannakis G, Mägerlein W, Kranich R (2001) Total Synthesis of Colombiasin A. Angewandte Chemie -
International Edition. [IF=2.456, Cited=8, 29712275].
- Nicolaou KC, Gray D, Tae J (2001) Total Synthesis of Hamigerans: Part 1. Development of Synthetic Technology for the
Construction of Benzannulated Polycyclic Systems by the Intramolecular Trapping of Photogenerated Hydroxy-o-
quinodimethanes and Synthesis of Key Building Blocks This work was financially supported by the National Institutes of
Health (USA) and The Skaggs Institute for Chemical Biology, and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-
Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Pfizer, and Schering Plough. Angewandte Chemie - International
Edition. [IF=2.456, Cited=21, 11592219].
- Nicolaou KC, Gray D, Tae J (2001) Total Synthesis of Hamigerans: Part 2. Implementation of the Intramolecular Diels-
Alder Trapping of Photochemically Generated Hydroxy-o-quinodimethanes; Strategy and Completion of the Synthesis This
work was financially supported by the National Institutes of Health (USA) and The Skaggs Institute for Chemical Biology,
and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Pfizer,
and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=20, 11592220].
- Nicolaou KC, Li Y, Wei HX, Weyershausen B (2001) Total Synthesis of Apoptolidin: Part 1. Retrosynthetic Analysis and
Construction of Building Blocks. Angewandte Chemie - International Edition. [IF=2.456, Cited=1, 29712121].
- Nicolaou KC, Li Y, Sugita K (2001) Total Synthesis of Apoptolidin: Part 2. Coupling of Key Building Blocks and
Completion of the Synthesis. Angewandte Chemie - International Edition. [IF=2.456, Cited=2, 29712136].
- Nicolaou KC, Qian W, Bernal F, ..., Hinrichs J (2001) Synthesis of the ABCD Ring System of Azaspiracid. Angewandte
Chemie - International Edition. [IF=2.456, Cited=2, 29712267].
- Nicolaou KC, Li J (2001) "Biomimetic" Cascade Reactions in Organic Synthesis: Construction of
4-Oxatricyclo[4.3.1.0]decan-2-one Systems and Total Synthesis of 1-O-Methylforbesione via Tandem Claisen
Rearrangement/Diels-Alder Reactions. Angewandte Chemie - International Edition. [IF=2.456, Cited=13, 29712093].
- Nicolaou KC, Vassilikogiannakis G (2001) cis-3,4-Dichlorocyclobutene as a Versatile Synthon in Organic Synthesis. Rapid
Entry into Complex Polycyclic Systems with Remarkably Stereospecific Reactions We thank Drs. D. H. Huang and G. Siuzdak
for their assistance with NMR spectroscopy and mass spectrometry, respectively. This work was financially supported by
the National Institutes of Health (USA) and The Skaggs Institute for Chemical Biology, a postdoctoral fellowship from
the Skaggs Institute for Research (to V.G.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo,
Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie - International Edition.
[IF=2.456, Cited=8, 12404439].
- Nicolaou KC, Huang X, Giuseppone N, ..., Snyder SA (2001) Construction of the Complete Aromatic Core of Diazonamide A by
a Novel Hetero Pinacol Macrocyclization Cascade Reaction We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic
and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute
for Chemical Biology, the National Institutes of Health (USA), American Biosciences, a predoctoral fellowship from the
National Science Foundation (S.A.S.), a postdoctoral fellowship from the Association pour la Recherche sur le Cancer
(N.G.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck,
Novartis, Pfizer, and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=10, 12404390].
- Nicolaou KC, Huang X, Bheema Rao P, Bella M (2002) A novel regio- and stereoselective synthesis of sulfamidates from
1,2-diols using Burgess and related reagents: a facile entry into beta-amino alcohols. Angewandte Chemie - International
Edition. [IF=2.456, Cited=10, 12491352].
- Nicolaou KC, Montagnon T (2002) Modulation of the reactivity profile of IBX by ligand complexation: ambient temperature
dehydrogenation of aldehydes and ketones to alpha,beta-unsaturated carbonyl compounds. Angewandte Chemie - International
Edition. [IF=2.456, Cited=54, 12491291].
- Nicolaou KC, Gray DLF, Montagnon T, Harrison ST (2002) Oxidation of silyl enol ethers by using IBX and IBX.N-oxide
complexes: a mild and selective reaction for the synthesis of enones. Angewandte Chemie - International Edition.
[IF=2.456, Cited=49, 12491292].
- Nicolaou KC, Montagnon T (2002) HIO3 and I2O5: mild and selective alternative reagents to IBX for the dehydrogenation of
aldehydes and ketones. Angewandte Chemie - International Edition. [IF=2.456, Cited=20, 19750773].
- Nicolaou KC, Montagnon T, Vassilikogiannakis G (2002) The Diels--Alder reaction in total synthesis. Angewandte Chemie -
International Edition. [IF=2.456, Cited=381, 19750686].
- Nicolaou KC (2002) The CP molecule labyrinth: a paradigm of how endeavors in total synthesis lead to discoveries and
inventions in organic synthesis. Angewandte Chemie - International Edition. [IF=2.456, Cited=6, 12203464].
- Nicolaou KC, Vassilikogiannakis G, Montagnon T (2002) The total synthesis of coleophomones B and C. Angewandte Chemie -
International Edition. [IF=2.456, Cited=7, 12207414].
- Nicolaou KC, Bella M, Chen DYK, ..., Ling T (2002) Total synthesis of diazonamide A. Angewandte Chemie - International
Edition. [IF=2.456, Cited=46, 12298077].
- Nicolaou KC, Kim DW, Baati R (2002) Stereocontrolled total synthesis of apicularen A and its delta(17,18) Z isomer.
Angewandte Chemie - International Edition. [IF=2.456, Cited=25, 12370936].
- Nicolaou KC, Longbottom DA, Nalbanadian AZ, Huang X (2002) A new method for the synthesis of nonsymmetrical sulfamides
using burgess-type reagents. Angewandte Chemie - International Edition. [IF=2.456, Cited=5, 12386873].
- Nicolaou KC, Bheema Rao P, Hao J, ..., Chen DYK (2003) The second total synthesis of diazonamide A. Angewandte Chemie -
International Edition. [IF=2.456, Cited=49, 12707898].
- Nicolaou KC, Roecker AJ, Monenschein H, ..., Follmann M (2003) Studies towards the synthesis of azadirachtin:
enantioselective entry into the azadirachtin framework through cascade reactions. Angewandte Chemie - International
Edition. [IF=2.456, Cited=11, 12916035].
- Nicolaou KC, Nevalainen M, Zak M, ..., Safina BS (2003) Synthetic studies on thiostrepton: construction of thiostrepton
analogues with the thiazoline-containing macrocycle. Angewandte Chemie - International Edition. [IF=2.456, Cited=16, 12888975].
- Nicolaou KC, Sasmal PK, Xu H, ..., Ritzén A (2003) Total synthesis of 1-O-methyllateriflorone. Angewandte Chemie -
International Edition. [IF=2.456, Cited=12, 14502742].
- Nicolaou KC, Sasmal PK, Rassias G, ..., Giannakakou P (2003) Design, synthesis, and biological properties of highly
potent epothilone B analogues. Angewandte Chemie - International Edition. [IF=2.456, Cited=19, 12900969].
- Nicolaou KC, Li Y, Uesaka N, ..., Chen DYK (2003) Total synthesis of the proposed azaspiracid-1 structure, part 1:
construction of the enantiomerically pure C1-C20, C21-C27, and C28-C40 fragments. Angewandte Chemie - International
Edition. [IF=2.456, Cited=27, 12916036].
- Nicolaou KC, Chen DYK, Li Y, ..., Uesaka N (2003) Total synthesis of the proposed azaspiracid-1 structure, part 2:
coupling of the C1-C20, C21-C27, and C28-C40 fragments and completion of the synthesis. Angewandte Chemie -
International Edition. [IF=2.456, Cited=28, 12916037].
- Nicolaou KC, Mathison CJN, Montagnon T (2003) New reactions of IBX: oxidation of nitrogen- and sulfur-containing
substrates to afford useful synthetic intermediates. Angewandte Chemie - International Edition. [IF=2.456, Cited=42, 12973775].
- Nicolaou KC, Vyskocil S, Koftis TV, ..., Satake M (2004) Structural revision and total synthesis of azaspiracid-1, part
1: intelligence gathering and tentative proposal. Angewandte Chemie - International Edition. [IF=2.456, Cited=33, 15368380].
- Nicolaou KC, Koftis TV, Vyskocil S, ..., Frederick MO (2004) Structural revision and total synthesis of azaspiracid-1,
part 2: definition of the ABCD domain and total synthesis. Angewandte Chemie - International Edition. [IF=2.456,
Cited=46, 15368381].
- Nicolaou KC (2005) Chasing molecules that were never there: misassigned natural products and the role of chemical
synthesis in modern structure elucidation. Angewandte Chemie - International Edition. [IF=2.456, Cited=157, 15688428].
- Nicolaou KC, Safina BS, Zak M, ..., Lee SH (2004) Total synthesis of thiostrepton, part 1: construction of the
dehydropiperidine/thiazoline-containing macrocycle. Angewandte Chemie - International Edition. [IF=2.456, Cited=30, 15372631].
- Nicolaou KC, Zak M, Safina BS, ..., Estrada AA (2004) Total synthesis of thiostrepton, part 2: construction of the
quinaldic acid macrocycle and final stages of the synthesis. Angewandte Chemie - International Edition. [IF=2.456,
Cited=35, 15372630].
- Nicolaou KC, Estrada AA, Zak M, ..., Safina BS (2005) A mild and selective method for the hydrolysis of esters with
trimethyltin hydroxide. Angewandte Chemie - International Edition. [IF=2.456, Cited=101, 15674985].
- Nicolaou KC, Xu H, Wartmann M (2005) Biomimetic total synthesis of gambogin and rate acceleration of pericyclic
reactions in aqueous media. Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 15657969].
- Nicolaou KC, Sasmal PK, Roecker AJ, ..., Converso A (2005) Studies toward the synthesis of azadirachtin, part 1: total
synthesis of a fully functionalized ABC ring framework and coupling with a norbornene domain. Angewandte Chemie -
International Edition. [IF=2.456, Cited=13, 15846829].
- Nicolaou KC, Sasmal PK, Koftis TV, ..., Petrovic G (2005) Studies toward the synthesis of azadirachtin, part 2:
construction of fully functionalized ABCD ring frameworks and unusual intramolecular reactions induced by close-
proximity effects. Angewandte Chemie - International Edition. [IF=2.456, Cited=13, 15849805].
- Nicolaou KC, Bulger PG, Sarlah D (2005) Palladium-catalyzed cross-coupling reactions in total synthesis. Angewandte
Chemie - International Edition. [IF=2.456, Cited=513, 15991198].
- Nicolaou KC, Bulger PG, Sarlah D (2005) Metathesis reactions in total synthesis. Angewandte Chemie - International
Edition. [IF=2.456, Cited=307, 16003791].
- Nicolaou KC, Kim DW, Schlawe D, ..., Longbottom DA (2005) Total synthesis of halipeptins A and D and analogues.
Angewandte Chemie - International Edition. [IF=2.456, Cited=11, 16010700].
- Nicolaou KC, Lee SH, Estrada AA, Zak M (2005) Construction of substituted N-hydroxyindoles: synthesis of a nocathiacin I
model system. Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 15892095].
- Nicolaou KC, Carenzi GEA, Jeso V (2005) Construction of highly functionalized medium-sized rings: synthesis of
hyperforin and perforatumone model systems. Angewandte Chemie - International Edition. [IF=2.456, Cited=13, 15892032].
- Nicolaou KC, Tang W, Dagneau P, Faraoni R (2005) A catalytic asymmetric three-component 1,4-addition/aldol reaction:
enantioselective synthesis of the spirocyclic system of vannusal A. Angewandte Chemie - International Edition.
[IF=2.456, Cited=20, 15900527].
- Nicolaou KC, Mathison CJN (2005) Synthesis of imides, N-acyl vinylogous carbamates and ureas, and nitriles by oxidation
of amides and amines with Dess-Martin periodinane. Angewandte Chemie - International Edition. [IF=2.456, Cited=30, 16124020].
- Nicolaou KC, Papageorgiou CD, Piper JL, Chadha RK (2005) The cytoskyrin cascade: a facile entry into cytoskyrin A,
deoxyrubroskyrin, rugulin, skyrin, and flavoskyrin model systems. Angewandte Chemie - International Edition. [IF=2.456,
Cited=14, 16123947].
- Nicolaou KC, Lim YH, Papageorgiou CD, Piper JL (2005) Total synthesis of (+)-rugulosin and (+)-2,2'-epi-cytoskyrin A
through cascade reactions. Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 16342134].
- Nicolaou KC, Denton RM, Lenzen A, ..., Harrison ST (2006) Stereocontrolled synthesis of model core systems of
lomaiviticins A and B. Angewandte Chemie - International Edition. [IF=2.456, Cited=17, 16496276].
- Nicolaou KC, Frederick MO, Petrovic G, ..., Loizidou EZ (2006) Total synthesis and confirmation of the revised
structures of azaspiracid-2 and azaspiracid-3. Angewandte Chemie - International Edition. [IF=2.456, Cited=28, 16548033].
- Nicolaou KC, Harrison ST (2006) Total synthesis of abyssomicin C and atrop-abyssomicin C. Angewandte Chemie -
International Edition. [IF=2.456, Cited=35, 16634106].
- Nicolaou KC, Estrada AA, Lee SH, Freestone GC (2006) Synthesis of highly substituted N-hydroxyindoles through
1,5-addition of carbon nucleophiles to in situ generated unsaturated nitrones. Angewandte Chemie - International
Edition. [IF=2.456, Cited=8, 16847981].
- Nicolaou KC, Nold AL, Milburn RR, Schindler CS (2006) Total synthesis of marinomycins A-C. Angewandte Chemie -
International Edition. [IF=2.456, Cited=18, 16977657].
- Nicolaou KC, Edmonds DJ, Bulger PG (2006) Cascade reactions in total synthesis. Angewandte Chemie - International
Edition. [IF=2.456, Cited=481, 17075967].
- Nicolaou KC, Zou B, Dethe DH, ..., Chen DYK (2006) Total synthesis of antibiotics GE2270A and GE2270T. Angewandte Chemie
- International Edition. [IF=2.456, Cited=27, 17061302].
- Nicolaou KC, Li A, Edmonds DJ (2006) Total synthesis of platensimycin. Angewandte Chemie - International Edition.
[IF=2.456, Cited=62, 17013803].
- Nicolaou KC, Frederick MO (2007) On the structure of maitotoxin. Angewandte Chemie - International Edition. [IF=2.456,
Cited=17, 17469088].
- Nicolaou KC, Edmonds DJ, Li A, Tria GS (2007) Asymmetric total syntheses of platensimycin. Angewandte Chemie -
International Edition. [IF=2.456, Cited=54, 17444571].
- Nicolaou KC, Zhang H, Chen JS, ..., Pasunoori L (2007) Total synthesis and stereochemistry of uncialamycin. Angewandte
Chemie - International Edition. [IF=2.456, Cited=22, 17497617].
- Nicolaou KC, Lister T, Denton RM, ..., Edmonds DJ (2007) Adamantaplatensimycin: a bioactive analogue of platensimycin.
Angewandte Chemie - International Edition. [IF=2.456, Cited=46, 17514775].
- Nicolaou KC, Sarlah D, Shaw DM (2007) Total synthesis and revised structure of biyouyanagin A. Angewandte Chemie -
International Edition. [IF=2.456, Cited=30, 17523208].
- Nicolaou KC, Majumder U, Roche SP, Chen DYK (2007) Construction of the "left domain" of haplophytine. Angewandte Chemie
- International Edition. [IF=2.456, Cited=13, 17559182].
- Nicolaou KC, Guduru R, Sun YP, ..., Chen DYK (2007) Total synthesis of the originally proposed and revised structures of
palmerolide A. Angewandte Chemie - International Edition. [IF=2.456, Cited=23, 17600809].
- Nicolaou KC, Lister T, Denton RM, Gelin CF (2007) Cascade reactions involving formal [2+2] thermal cycloadditions: total
synthesis of artochamins F, H, I, and J. Angewandte Chemie - International Edition. [IF=2.456, Cited=10, 17768746].
- Nicolaou KC, Cole KP, Frederick MO, ..., Denton RM (2007) Chemical synthesis of the GHIJK ring system and further
experimental support for the originally assigned structure of maitotoxin. Angewandte Chemie - International Edition.
[IF=2.456, Cited=19, 17943950].
- Nicolaou KC, Chen JS, Zhang H, Montero A (2008) Asymmetric synthesis and biological properties of uncialamycin and
26-epi-uncialamycin. Angewandte Chemie - International Edition. [IF=2.456, Cited=15, 18058881].
- Nicolaou KC, Pappo D, Tsang KY, ..., Chen DYK (2008) A chiral pool based synthesis of platensimycin. Angewandte Chemie -
International Edition. [IF=2.456, Cited=31, 18176919].
- Nicolaou KC, Wang J, Tang Y (2008) Synthesis of the sporolide ring framework through a cascade sequence involving an
intramolecular [4+2] cycloaddition reaction of an o-quinone. Angewandte Chemie - International Edition. [IF=2.456,
Cited=6, 18205155].
- Nicolaou KC, Tria GS, Edmonds DJ (2008) Total synthesis of platencin. Angewandte Chemie - International Edition.
[IF=2.456, Cited=44, 18246566].
- Nicolaou KC, Krasovskiy A, Trépanier VE, Chen DYK (2008) An expedient strategy for the synthesis of tryptamines and
other heterocycles. Angewandte Chemie - International Edition. [IF=2.456, Cited=6, 18404758].
- Nicolaou KC, Chen JS, Edmonds DJ, Estrada AA (2009) Recent advances in the chemistry and biology of naturally occurring
antibiotics. Angewandte Chemie - International Edition. [IF=2.456, Cited=62, 19130444].
- Nicolaou KC, Frederick MO, Aversa RJ (2008) The continuing saga of the marine polyether biotoxins. Angewandte Chemie -
International Edition. [IF=2.456, Cited=46, 18763702].
- Nicolaou KC, Li A (2008) Total syntheses and structural revision of alpha- and beta-diversonolic esters and total
syntheses of diversonol and blennolide C. Angewandte Chemie - International Edition. [IF=2.456, Cited=29, 18651685].
- Nicolaou KC, Sun YP, Peng XS, ..., Chen DYK (2008) Total synthesis of (+)-cortistatin A. Angewandte Chemie -
International Edition. [IF=2.456, Cited=33, 18704899].
- Nicolaou KC, Zhang H, Ortiz A, Dagneau P (2008) Total synthesis of the originally assigned structure of vannusal B.
Angewandte Chemie - International Edition. [IF=2.456, Cited=14, 18850598].
- Nicolaou KC, Lim YH, Becker J (2009) Total synthesis and absolute configuration of the bisanthraquinone antibiotic
BE-43472B. Angewandte Chemie - International Edition. [IF=2.456, Cited=11, 19235819].
- Nicolaou KC, Tang Y, Wang J (2009) Total synthesis of sporolide B. Angewandte Chemie - International Edition. [IF=2.456,
Cited=20, 19241430].
- Nicolaou KC, Wu TR, Kang Q, Chen DYK (2009) Total synthesis of hopeahainol A and hopeanol. Angewandte Chemie -
International Edition. [IF=2.456, Cited=27, 19280619].
- Nicolaou KC, Li A, Ellery SP, Edmonds DJ (2009) Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal
alkynes and formal total synthesis of (-)-platensimycin. Angewandte Chemie - International Edition. [IF=2.456,
Cited=20, 19606433].
- Nicolaou KC, Zhang H, Ortiz A (2009) The true structures of the vannusals, part 1: Initial forays into suspected
structures and intelligence gathering. Angewandte Chemie - International Edition. [IF=2.456, Cited=8, 19562816].
- Nicolaou KC, Ortiz A, Zhang H (2009) The true structures of the vannusals, part 2: Total synthesis and revised structure
of vannusal B. Angewandte Chemie - International Edition. [IF=2.456, Cited=10, 19562817].
- Nicolaou KC, Ellery SP, Chen JS (2009) Samarium diiodide mediated reactions in total synthesis. Angewandte Chemie -
International Edition. [IF=2.456, Cited=111, 19714695].
- Nicolaou KC, Nold AL, Li H (2009) Synthesis of the monomeric unit of the lomaiviticin aglycon. Angewandte Chemie -
International Edition. [IF=2.456, Cited=15, 19575434].
- Nicolaou KC, Sarlah D, Wu TR, Zhan W (2009) Total synthesis of hirsutellone B. Angewandte Chemie - International
Edition. [IF=2.456, Cited=24, 19685548].
- Nicolaou KC, Dalby SM, Li S, ..., Chen DYK (2009) Total synthesis of (+)-haplophytine. Angewandte Chemie - International
Edition. [IF=2.456, Cited=33, 19746386].
- Nicolaou KC, Sun YP, Korman H, Sarlah D (2010) Asymmetric total synthesis of cylindrocyclophanes A and F through
cyclodimerization and a Ramberg-Bäcklund reaction. Angewandte Chemie - International Edition. [IF=2.456, Cited=17, 20623817].
- Nicolaou KC (2011) Invigorating education. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 21132824].
- Nicolaou KC, Jiang X, Lindsay-Scott PJ, ..., Fowler VM (2011) Total synthesis and biological evaluation of
monorhizopodin and 16-epi-monorhizopodin. Angewandte Chemie - International Edition. [IF=2.456, Cited=17, 21268213].
- Nicolaou KC, Adsool VA, Hale CRH (2011) An expedient synthesis of a functionalized core structure of bielschowskysin.
Angewandte Chemie - International Edition. [IF=2.456, Cited=6, 21523870].
- Nicolaou KC, Giguère D, Totokotsopoulos S, Sun YP (2011) A practical sulfenylation of 2,5-diketopiperazines. Angewandte
Chemie - International Edition. [IF=2.456, Cited=18, 22162254].
- Nicolaou KC, Hale CRH, Ebner C, ..., Rhoades D (2012) Synthesis of macroheterocycles through intramolecular oxidative
coupling of furanoid β-ketoesters. Angewandte Chemie - International Edition. [IF=2.456, Cited=9, 22489095].
- Nicolaou KC (2012) How thiostrepton was made in the laboratory. Angewandte Chemie - International Edition. [IF=2.456,
Cited=11, 23208736].
- Nicolaou KC (2012) The emergence of the structure of the molecule and the art of its synthesis. Angewandte Chemie -
International Edition. [IF=2.456, Cited=6, 23203813].
- Nicolaou KC, Nilewski C, Hale CRH, ..., Koch LG (2013) Total synthesis and structural revision of viridicatumtoxin B.
Angewandte Chemie - International Edition. [IF=2.456, Cited=10, 23893651].
- Nicolaou KC, Frederick MO, Loizidou EZ, ..., Yamada YMA (2006) Second-generation total synthesis of azaspiracids-1, -2,
and -3. Chemistry - An Asian Journal. [IF=0.736, Cited=16, 17441061].
- Nicolaou KC, Dethe DH, Leung GYC, ..., Chen DYK (2008) Total synthesis of thiopeptide antibiotics GE2270A, GE2270T, and
GE2270C1. Chemistry - An Asian Journal. [IF=0.736, Cited=32, 18188863].
- Nicolaou KC, Kim DW, Baati R, ..., Giannakakou P (2003) Total synthesis and biological evaluation of (-)apicularen A and
analogues thereof. Chemistry - A European Journal. [IF=0.899, Cited=13, 14679529].
- Nicolaou KC, Longbottom DA, Nalbandian AZ, Huang X (2004) New uses for the Burgess reagent in chemical synthesis:
methods for the facile and stereoselective formation of sulfamidates, glycosylamines, and sulfamides. Chemistry - A
European Journal. [IF=0.899, Cited=18, 15470695].
- Nicolaou KC, Schlawe D, Kim DW, ..., Faulkner DJ (2005) Total synthesis of halipeptins: isolation of halipeptin D and
synthesis of oxazoline halipeptin analogues. Chemistry - A European Journal. [IF=0.899, Cited=9, 16075448].
- Nicolaou KC, Sanchini S, Wu TR, Sarlah D (2010) Total synthesis and structural revision of biyouyanagin B. Chemistry - A
European Journal. [IF=0.899, Cited=8, 20572192].
- Nicolaou KC, Pratt BA, Arseniyadis S, ..., Giannakakou P (2006) Molecular design and chemical synthesis of a highly
potent epothilone. ChemMedChem. [IF=0.766, Cited=17, 16892332].
- Nicolaou KC, Aversa RJ (2011) Maitotoxin: An Inspiration for Synthesis. Israel Journal of Chemistry. [IF=0.673,
Cited=12, 21709816].
- Nicolaou KC, Hale CRH, Nilewski C (2012) A total synthesis trilogy: calicheamicin γ1(I), Taxol®, and brevetoxin A.
Chemical Record. [IF=1.183, Cited=8, 22711588].
- Nicolaou KC, Marron BE, Veale CA, ..., Serhan CN (1989) Identification of a novel 7-cis-11-trans-lipoxin A4 generated by
human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4
and B4. None. [IF=None, Cited=10, 2713393].
- Nicolaou KC, Caulfield TJ, Katoaka H (1990) Total synthesis of globotriaosylceramide (Gb3) and lysoglobotriaosylceramide
(lysoGb3). Carbohydrate Research. [IF=0.688, Cited=18, 2224889].
- Nicolaou KC, Pitsinos EN, Theodorakis EA, ..., Wrasidlo W (1994) Synthetic calicheamicin mimics with novel initiation
mechanisms: DNA cleavage, cytotoxicity, and apoptosis. None. [IF=None, Cited=15, 9383371].
- Smee DF, Evans WJ, Nicolaou KC, ..., Day CW (2016) Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus
87 strains to various antiviral compounds. Antiviral Research. [IF=1.4, Cited=34, 27063860].
- Nicolaou KC, Chen JS, Dalby SM (2008) From nature to the laboratory and into the clinic. Bioorganic and Medicinal
Chemistry. [IF=0.86, Cited=24, 19028103].
- Nicolaou KC, Ellery SP, Rivas F, ..., Burton D (2011) Synthesis and biological evaluation of 2',4'- and 3',4'-bridged
nucleoside analogues. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=7, 21840722].
- Nicolaou KC, Valiulin RA, Pokorski JK, ..., Chen JS (2012) Bio-inspired synthesis and biological evaluation of a
colchicine-related compound library. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=12, 22542017].
- Nicolaou KC, Estrada AA, Freestone GC, ..., Alvarez-Mico X (2007) New synthetic technology for the construction of
N-hydroxyindoles and synthesis of nocathiacin I model systems. Tetrahedron. [IF=0.579, Cited=12, 20606766].
- Nicolaou KC, Lister T, Denton RM, Gelin CF (2008) Total synthesis of atrochamins F, H, I, and J through cascade
reactions. Tetrahedron. [IF=0.579, Cited=9, 19461992].
- Nicolaou KC, Simmons NL, Chen JS, ..., Nizet V (2011) Total synthesis and biological evaluation of marinopyrrole A and
analogues. Tetrahedron Letters. [IF=0.515, Cited=18, 21499535].
- Ferreiro SF, Vilariño N, Louzao MC, ..., Botana LM (2014) In vitro chronic effects on hERG channel caused by the marine
biotoxin azaspiracid-2. Toxicon. [IF=0.916, Cited=4, 25286396].
- Nicolaou KC, Roecker AJ, Hughes R, ..., Winssinger N (2003) Novel strategies for the solid phase synthesis of
substituted indolines and indoles. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=3, 12517442].
- Nicolaou KC, Trujillo JI, Jandeleit B, ..., Goodman SL (1998) Design, synthesis and biological evaluation of nonpeptide
integrin antagonists. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=27, 9784861].
- Nicolaou KC, King NP, Finlay MR, ..., Hepworth D (1999) Total synthesis of epothilone E and related side-chain modified
analogues via a Stille coupling based strategy. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=19, 10400321].
- Nicolaou KC, Scarpelli R, Bollbuck B, ..., Giannakakou P (2000) Chemical synthesis and biological properties of pyridine
epothilones. None. [IF=None, Cited=43, 11048950].
- Nicolaou KC, Finlay MR, Ninkovic S, ..., Vourloumis D (1998) Synthesis and biological properties of C12,13-cyclopropyl-
epothilone A and related epothilones. None. [IF=None, Cited=12, 9662505].
- Hirschmann RF, Nicolaou KC, Angeles AR, ..., Smith AB (2009) The beta-D-glucose scaffold as a beta-turn mimetic.
Accounts of Chemical Research. [IF=3.533, Cited=25, 19624154].
- Wrasidlo W, Gaedicke G, Guy RK, ..., Lode HN (2002) A novel 2'-(N-methylpyridinium acetate) prodrug of paclitaxel
induces superior antitumor responses in preclinical cancer models. Bioconjugate Chemistry. [IF=0.921, Cited=18, 12236791].
- Narayana N, Diller TC, Koide K, ..., Taylor SS (1999) Crystal structure of the potent natural product inhibitor balanol
in complex with the catalytic subunit of cAMP-dependent protein kinase. Biochemistry. [IF=0.753, Cited=53, 10029530].
- Hamel E, Sackett DL, Vourloumis D, Nicolaou KC (1999) The coral-derived natural products eleutherobin and sarcodictyins
A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the
polymer taxoid site. Biochemistry. [IF=0.753, Cited=57, 10220336].
- Nicolaou KC, Namoto K, Ritzén A, ..., Giannakakou P (2001) Chemical synthesis and biological evaluation of cis- and
trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues. Journal of the
American Chemical Society. [IF=2.573, Cited=45, 11562214].
- Nicolaou KC, Jung J, Yoon WH, ..., Baran PS (2002) Total synthesis of the CP-molecules (CP-263,114 and CP-225,917,
phomoidrides B and A). 1. Racemic and asymmetric synthesis of bicyclo[4.3.1] key building blocks. Journal of the
American Chemical Society. [IF=2.573, Cited=8, 11878972].
- Nicolaou KC, Baran PS, Zhong YL, ..., Choi HS (2002) Total synthesis of the CP-molecules (CP-263,114 and CP-225,917,
phomoidrides B and A). 2. Model studies for the construction of key structural elements and first-generation strategy.
Journal of the American Chemical Society. [IF=2.573, Cited=12, 11878973].
- Nicolaou KC, Zhong YL, Baran PS, ..., Yoon WH (2002) Total synthesis of the CP-molecules (CP-263,114 and CP-225,917,
phomoidrides B and A). 3. Completion and synthesis of advanced analogues. Journal of the American Chemical Society.
[IF=2.573, Cited=9, 11878974].
- Nicolaou KC, Baran PS, Zhong YL, Sugita K (2002) Iodine(V) reagents in organic synthesis. Part 1. Synthesis of
polycyclic heterocycles via Dess-Martin periodinane-mediated cascade cyclization: generality, scope, and mechanism of
the reaction. Journal of the American Chemical Society. [IF=2.573, Cited=26, 11878975].
- Nicolaou KC, Sugita K, Baran PS, Zhong YL (2002) Iodine(V) reagents in organic synthesis. Part 2. Access to complex
molecular architectures via Dess-Martin periodinane-generated o-imidoquinones. Journal of the American Chemical Society.
[IF=2.573, Cited=20, 11878976].
- Nicolaou KC, Baran PS, Zhong YL, ..., Vega JA (2002) Iodine(V) reagents in organic synthesis. Part 3. New routes to
heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: generality, scope, and mechanism. Journal of the
American Chemical Society. [IF=2.573, Cited=65, 11878977].
- Nicolaou KC, Montagnon T, Baran PS, Zhong YL (2002) Iodine(V) reagents in organic synthesis. Part 4. o-Iodoxybenzoic
acid as a chemospecific tool for single electron transfer-based oxidation processes. Journal of the American Chemical
Society. [IF=2.573, Cited=111, 11878978].
- Nicolaou KC, Montagnon T, Ulven T, ..., Sarabia F (2002) Novel chemistry of alpha-tosyloxy ketones: applications to the
solution- and solid-phase synthesis of privileged heterocycle and enediyne libraries. Journal of the American Chemical
Society. [IF=2.573, Cited=8, 12010045].
- Nicolaou KC (2002) Atropselective macrocyclization of diaryl ether ring systems: application to the synthesis of
vancomycin model systems. Journal of the American Chemical Society. [IF=2.573, Cited=20, 12197747].
- Nicolaou KC, Monenschein H, Li Y, ..., Sugita K (2003) Total synthesis of apoptolidin: construction of enantiomerically
pure fragments. Journal of the American Chemical Society. [IF=2.573, Cited=34, 14664589].
- Nicolaou KC, Li Y, Sugita K, ..., O'Brate A (2003) Total synthesis of apoptolidin: completion of the synthesis and
analogue synthesis and evaluation. Journal of the American Chemical Society. [IF=2.573, Cited=30, 14664590].
- Nicolaou KC, Gray DLF (2004) Total synthesis of hybocarpone and analogues thereof. A facile dimerization of
naphthazarins to pentacyclic systems. Journal of the American Chemical Society. [IF=2.573, Cited=28, 14719960].
- Nicolaou KC, Gray DLF, Tae J (2004) Total synthesis of hamigerans and analogues thereof. Photochemical generation and
Diels-Alder trapping of hydroxy-o-quinodimethanes. Journal of the American Chemical Society. [IF=2.573, Cited=46, 14719961].
- Nicolaou KC, Sasmal PK, Xu H (2004) Biomimetically inspired total synthesis and structure activity relationships of
1-O-methyllateriflorone. 6 pi electrocyclizations in organic synthesis. Journal of the American Chemical Society.
[IF=2.573, Cited=25, 15113221].
- Nicolaou KC, Mathison CJN, Montagnon T (2004) o-Iodoxybenzoic acid (IBX) as a viable reagent in the manipulation of
nitrogen- and sulfur-containing substrates: scope, generality, and mechanism of IBX-mediated amine oxidations and
dithiane deprotections. Journal of the American Chemical Society. [IF=2.573, Cited=70, 15099102].
- Nicolaou KC, Huang X, Simonsen KB, ..., Bigot A (2004) Studies toward diazonamide A: initial synthetic forays directed
toward the originally proposed structure. Journal of the American Chemical Society. [IF=2.573, Cited=28, 15303892].
- Nicolaou KC, Giuseppone N, Huang X, ..., Giannakakou P (2004) Studies toward diazonamide A: development of a hetero-
pinacol macrocyclization cascade for the construction of the bis-macrocyclic framework of the originally proposed
structure. Journal of the American Chemical Society. [IF=2.573, Cited=13, 15303893].
- Nicolaou KC, Chen DYK, Huang X, ..., Bella M (2004) Chemistry and biology of diazonamide A: first total synthesis and
confirmation of the true structure. Journal of the American Chemical Society. [IF=2.573, Cited=54, 15469286].
- Nicolaou KC, Hao J, Rao PB, ..., Giannakakou P (2004) Chemistry and biology of diazonamide A: second total synthesis and
biological investigations. Journal of the American Chemical Society. [IF=2.573, Cited=49, 15469287].
- Nicolaou KC, Nalbandian AZ, Longbottom DA (2004) A new method for the stereoselective synthesis of alpha- and beta-
glycosylamines using the Burgess reagent. Journal of the American Chemical Society. [IF=2.573, Cited=14, 15149212].
- Nicolaou KC, Montagnon T, Vassilikogiannakis G, Mathison CJN (2005) The total synthesis of coleophomones B, C, and D.
Journal of the American Chemical Society. [IF=2.573, Cited=29, 15954796].
- Nicolaou KC, Safina BS, Zak M, ..., Bulat S (2005) Total synthesis of thiostrepton. Retrosynthetic analysis and
construction of key building blocks. Journal of the American Chemical Society. [IF=2.573, Cited=41, 16076224].
- Nicolaou KC, Zak M, Safina BS, ..., Nevalainen M (2005) Total synthesis of thiostrepton. Assembly of key building blocks
and completion of the synthesis. Journal of the American Chemical Society. [IF=2.573, Cited=44, 16076225].
- Nicolaou KC, Bernal F, Frederick MO, ..., Zou N (2006) Total synthesis and structural elucidation of azaspiracid-1.
Construction of key building blocks for originally proposed structure. Journal of the American Chemical Society.
[IF=2.573, Cited=25, 16478178].
- Nicolaou KC, Chen DYK, Li Y, ..., Vyskocil S (2006) Total synthesis and structural elucidation of azaspiracid-1.
Synthesis-based analysis of originally proposed structures and indication of their non-identity to the natural product.
Journal of the American Chemical Society. [IF=2.573, Cited=25, 16478179].
- Nicolaou KC, Koftis TV, Vyskocil S, ..., Yamada YMA (2006) Total synthesis and structural elucidation of azaspiracid-1.
Final assignment and total synthesis of the correct structure of azaspiracid-1. Journal of the American Chemical
Society. [IF=2.573, Cited=37, 16506764].
- Nicolaou KC, Zak M, Rahimipour S, ..., Ghadiri MR (2005) Discovery of a biologically active thiostrepton fragment.
Journal of the American Chemical Society. [IF=2.573, Cited=37, 16248640].
- Nicolaou KC, Lizos DE, Kim DW, ..., Cirino G (2006) Total synthesis and biological evaluation of halipeptins A and D and
analogues. Journal of the American Chemical Society. [IF=2.573, Cited=18, 16569024].
- Nicolaou KC, Harrison ST (2007) Total synthesis of abyssomicin C, atrop-abyssomicin C, and abyssomicin D: implications
for natural origins of atrop-abyssomicin C. Journal of the American Chemical Society. [IF=2.573, Cited=41, 17212423].
- Nicolaou KC, Nold AL, Milburn RR, ..., Yamaguchi J (2007) Total synthesis of marinomycins A-C and of their monomeric
counterparts monomarinomycin A and iso-monomarinomycin A. Journal of the American Chemical Society. [IF=2.573,
Cited=21, 17249678].
- Nicolaou KC, Lim YH, Piper JL, Papageorgiou CD (2007) Total syntheses of 2,2'-epi-cytoskyrin A, rugulosin, and the
alleged structure of rugulin. Journal of the American Chemical Society. [IF=2.573, Cited=26, 17355133].
- Nicolaou KC, Li H, Nold AL, ..., Lenzen A (2007) Total synthesis of kinamycins C, F, and J. Journal of the American
Chemical Society. [IF=2.573, Cited=30, 17676854].
- Nicolaou KC, Tang Y, Wang J, ..., Montero A (2007) Total synthesis and antibacterial properties of carbaplatensimycin.
Journal of the American Chemical Society. [IF=2.573, Cited=44, 17988130].
- Nicolaou KC, Ortiz A, Zhang H, ..., Lizos DE (2010) Total synthesis and structural revision of vannusals A and B:
synthesis of the originally assigned structure of vannusal B. Journal of the American Chemical Society. [IF=2.573,
Cited=19, 20443561].
- Nicolaou KC, Ortiz A, Zhang H, Guella G (2010) Total synthesis and structural revision of vannusals A and B: synthesis
of the true structures of vannusals A and B. Journal of the American Chemical Society. [IF=2.573, Cited=15, 20443558].
- Nicolaou KC, Aversa RJ, Jin J, Rivas F (2010) Synthesis of the ABCDEFG ring system of maitotoxin. Journal of the
American Chemical Society. [IF=2.573, Cited=14, 20415445].
- Nicolaou KC, Kang Q, Wu TR, ..., Chen DYK (2010) Total synthesis and biological evaluation of the resveratrol-derived
polyphenol natural products hopeanol and hopeahainol A. Journal of the American Chemical Society. [IF=2.573, Cited=42, 20462209].
- Nicolaou KC, Kang Q, Ng SY, Chen DYK (2010) Total synthesis of englerin A. Journal of the American Chemical Society.
[IF=2.573, Cited=48, 20496885].
- Nicolaou KC, Gelin CF, Seo JH, ..., Umezawa T (2010) Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and
86-epi-diastereoisomers. Journal of the American Chemical Society. [IF=2.573, Cited=14, 20666400].
- Nicolaou KC, Wang J, Tang Y, Botta L (2010) Total synthesis of sporolide B and 9-epi-sporolide B. Journal of the
American Chemical Society. [IF=2.573, Cited=15, 20698702].
- Nicolaou KC, Seo JH, Nakamura T, Aversa RJ (2010) Synthesis of the C'D'E'F' domain of maitotoxin. Journal of the
American Chemical Society. [IF=2.573, Cited=7, 21166429].
- Nicolaou KC, Baker TM, Nakamura T (2010) Synthesis of the WXYZA' domain of maitotoxin. Journal of the American Chemical
Society. [IF=2.573, Cited=12, 21166430].
- Saielli G, Nicolaou KC, Ortiz A, ..., Bagno A (2011) Addressing the stereochemistry of complex organic molecules by
density functional theory-NMR: vannusal B in retrospective. Journal of the American Chemical Society. [IF=2.573,
Cited=49, 21438587].
- Nicolaou KC, Simmons NL, Ying Y, ..., Chen JS (2011) Enantioselective dichlorination of allylic alcohols. Journal of the
American Chemical Society. [IF=2.573, Cited=71, 21542622].
- Nicolaou KC, Totokotsopoulos S, Giguère D, ..., Sarlah D (2011) Total synthesis of epicoccin G. Journal of the American
Chemical Society. [IF=2.573, Cited=40, 21548595].
- Bian M, Wang Z, Xiong X, ..., Li A (2012) Total syntheses of anominine and tubingensin A. Journal of the American
Chemical Society. [IF=2.573, Cited=39, 22537293].
- Nicolaou KC, Lu M, Totokotsopoulos S, ..., Winzeler EA (2012) Synthesis and biological evaluation of epidithio-,
epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of
epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new
antiviral and antimalarial agents. Journal of the American Chemical Society. [IF=2.573, Cited=41, 22978674].
- Nicolaou KC, Sun YP, Guduru R, ..., Chen DYK (2008) Total synthesis of the originally proposed and revised structures of
palmerolide A and isomers thereof. Journal of the American Chemical Society. [IF=2.573, Cited=30, 18298117].
- Nicolaou KC, Frederick MO, Burtoloso ACB, ..., Suzuki T (2008) Chemical Synthesis of the GHIJKLMNO Ring System of
Maitotoxin. Journal of the American Chemical Society. [IF=2.573, Cited=24, 18481856].
- Nicolaou KC, Leung GYC, Dethe DH, ..., Chen DYK (2008) Chemical synthesis and biological evaluation of palmerolide A
analogues. Journal of the American Chemical Society. [IF=2.573, Cited=18, 18598030].
- Nicolaou KC, Wu TR, Sarlah D, ..., Burton DR (2008) Total synthesis, revised structure, and biological evaluation of
biyouyanagin A and analogues thereof. Journal of the American Chemical Society. [IF=2.573, Cited=29, 18646750].
- Nicolaou KC, Stepan AF, Lister T, ..., Edmonds DJ (2008) Design, synthesis, and biological evaluation of platensimycin
analogues with varying degrees of molecular complexity. Journal of the American Chemical Society. [IF=2.573, Cited=49, 18771264].
- Nicolaou KC, Toh QY, Chen DYK (2008) An expedient asymmetric synthesis of platencin. Journal of the American Chemical
Society. [IF=2.573, Cited=30, 18665593].
- Nicolaou KC, Dalby SM, Majumder U (2008) A concise asymmetric total synthesis of aspidophytine. Journal of the American
Chemical Society. [IF=2.573, Cited=29, 18855359].
- Nicolaou KC, Krasovskiy A, Majumder U, ..., Chen DYK (2009) New synthetic technologies for the construction of
heterocycles and tryptamines. Journal of the American Chemical Society. [IF=2.573, Cited=12, 19243142].
- Nicolaou KC, Reingruber R, Sarlah D, Bräse S (2009) Enantioselective intramolecular Friedel-Crafts-type alpha-arylation
of aldehydes. Journal of the American Chemical Society. [IF=2.573, Cited=43, 19173649].
- Nicolaou KC, Peng XS, Sun YP, ..., Chen DYK (2009) Total synthesis and biological evaluation of cortistatins A and J and
analogues thereof. Journal of the American Chemical Society. [IF=2.573, Cited=33, 19722632].
- Nicolaou KC, Li A, Edmonds DJ, ..., Ellery SP (2009) Total synthesis of platensimycin and related natural products.
Journal of the American Chemical Society. [IF=2.573, Cited=41, 19874023].
- Nicolaou KC, Tria GS, Edmonds DJ, Kar M (2009) Total syntheses of (+/-)-platencin and (-)-platencin. Journal of the
American Chemical Society. [IF=2.573, Cited=26, 19824676].
- Nicolaou KC, Becker J, Lim YH, ..., Montero A (2009) Total synthesis and biological evaluation of (+)- and
(-)-bisanthraquinone antibiotic BE-43472B and related compounds. Journal of the American Chemical Society. [IF=2.573,
Cited=17, 19778008].
- Nicolaou KC, Ding H, Richard JA, Chen DYK (2010) Total synthesis of echinopines A and B. Journal of the American
Chemical Society. [IF=2.573, Cited=16, 20184316].
- Nicolaou KC (2005) Joys of molecules. 2. Endeavors in chemical biology and medicinal chemistry. Journal of Medicinal
Chemistry. [IF=1.655, Cited=7, 16134928].
- Vale C, Nicolaou KC, Frederick MO, ..., Botana LM (2007) Effects of azaspiracid-1, a potent cytotoxic agent, on primary
neuronal cultures. A structure-activity relationship study. Journal of Medicinal Chemistry. [IF=1.655, Cited=23, 17228878].
- Smith AL, Nicolaou KC (1996) The enediyne antibiotics. Journal of Medicinal Chemistry. [IF=1.655, Cited=121, 8667354].
- Nicolaou KC (2005) Joys of molecules. 1. Campaigns in total synthesis. Journal of Organic Chemistry. [IF=0.885,
Cited=7, 16122219].
- Nicolaou KC (2009) Inspirations, discoveries, and future perspectives in total synthesis. Journal of Organic Chemistry.
[IF=0.885, Cited=5, 19152273].
- Hayden AE, Paton RS, Becker J, ..., Houk KN (2010) Origins of regioselectivity of Diels-Alder reactions for the
synthesis of bisanthraquinone antibiotic BE-43472B. Journal of Organic Chemistry. [IF=0.885, Cited=3, 20027998].
- Nicolaou KC, Vassilikogiannakis G, Kranich R, ..., Natarajan S (2000) New Synthetic Technology for the Mild and
Selective One-Carbon Homologation of Hindered Aldehydes in the Presence of Ketones. Organic Letters. [IF=1.091,
Cited=4, 10891185].
- Hayden AE, Xu H, Nicolaou KC, Houk KN (2006) Origins of selectivity in pericyclic reaction cascades for the synthesis of
gambogin and lateriflorone. Organic Letters. [IF=1.091, Cited=7, 16805534].
- Nicolaou KC, Adsool VA, Hale CRH (2010) An expedient procedure for the oxidative cleavage of olefinic bonds with
PhI(OAc)2, NMO, and catalytic OsO4. Organic Letters. [IF=1.091, Cited=40, 20192259].
- Nicolaou KC, Kiappes JL, Tian W, ..., Becker J (2011) Synthesis of the carboline disaccharide domain of shishijimicin A.
Organic Letters. [IF=1.091, Cited=6, 21711032].
- Nicolaou KC, Sun YP, Sarlah D, ..., Wu TR (2011) Bioinspired synthesis of hirsutellones A, B, and C. Organic Letters.
[IF=1.091, Cited=14, 21913732].
- Nicolaou KC, Yu R, Shi L, ..., Heretsch P (2013) General synthetic approach to functionalized dihydrooxepines. Organic
Letters. [IF=1.091, Cited=13, 23550898].
- Nicolaou KC, He Y, Fong KC, ..., Baran PS (1999) Novel strategies to construct the gamma-hydroxy lactone moiety of the
CP molecules. Synthesis of the CP-225,917 core skeleton. Organic Letters. [IF=1.091, Cited=1, 10822534].
- Nicolaou KC, Baran PS, Zhong YL, ..., Yoon WH (1999) New synthetic technology for the synthesis of hindered alpha-
diazoketones via acyl mesylates. Organic Letters. [IF=1.091, Cited=7, 10823217].
- Nicolaou KC, Pfefferkorn JA, Cao GQ, ..., Kessabi J (1999) A facile method for the solution and solid-phase synthesis of
substituted [3.3.1] bicycles. Organic Letters. [IF=1.091, Cited=8, 10823208].
- Vilariño N, Nicolaou KC, Frederick MO, ..., Botana LM (2006) Cell growth inhibition and actin cytoskeleton
disorganization induced by azaspiracid-1 structure-activity studies. Chemical Research in Toxicology. [IF=0.994,
Cited=24, 17112233].
- Vilariño N, Nicolaou KC, Frederick MO, ..., Botana LM (2008) Azaspiracid substituent at C1 is relevant to in vitro
toxicity. Chemical Research in Toxicology. [IF=0.994, Cited=9, 18707138].
- Nicolaou KC, Yang Z, Shi G, ..., Gärtner P (1998) Total synthesis of brevetoxin A. Nature. [IF=11.591, Cited=40, 9521320].
- Nicolaou KC, Riemer C, Kerr MA, ..., Wrasidlo W (1993) Design, synthesis and biological activity of protaxols. Nature.
[IF=11.591, Cited=47, 8101355].
- Nicolaou KC, Yang Z, Liu JJ, ..., Paulvannan K (1994) Total synthesis of taxol. Nature. [IF=11.591, Cited=247, 7906395].
- Nicolaou KC, Winssinger N, Pastor J, ..., Hamel E (1997) Synthesis of epothilones A and B in solid and solution phase.
Nature. [IF=11.591, Cited=94, 9153390].
- Nicolaou KC, Boddy CN (2001) Behind enemy lines. None. [IF=None, Cited=6, 11341163].
- Nicolaou KC, Ritzén A, Namoto K (2001) Recent developments in the chemistry, biology and medicine of the epothilones.
Chemical Communications. [IF=0.902, Cited=34, 12240368].
- Nicolaou KC, Montagnon T (2003) Tandem reactions, cascade sequences, and biomimetic strategies in total synthesis.
Chemical Communications. [IF=0.902, Cited=141, 12669826].
- Nicolaou KC, Xu H (2006) Total synthesis of floresolide B and Delta(6,7)-Z-floresolide B. Chemical Communications.
[IF=0.902, Cited=19, 16446822].
- Nicolaou KC, Brenzovich WE, Bulger PG, Francis TM (2006) Synthesis of iso-epoxy-amphidinolide N and des-epoxy-
caribenolide I structures. Initial forays. Organic and Biomolecular Chemistry. [IF=0.77, Cited=22, 16729126].
- Nicolaou KC, Bulger PG, Brenzovich WE (2006) Synthesis of iso-epoxy-amphidinolide N and des-epoxy-caribenolide I
structures. Revised strategy and final stages. Organic and Biomolecular Chemistry. [IF=0.77, Cited=4, 16729127].
- Nicolaou KC, Tang Y, Wang J (2007) Formal synthesis of (+/-)-platensimycin. Chemical Communications. [IF=0.902,
Cited=33, 17695230].
- Nicolaou KC, Dethe DH, Chen DYK (2008) Total syntheses of amythiamicins A, B and C. Chemical Communications. [IF=0.902,
Cited=6, 18535690].
- Nicolaou KC, Chen JS (2009) The art of total synthesis through cascade reactions. Chemical Society Reviews. [IF=8.116,
Cited=200, 19847336].
- Nicolaou KC, Dong L, Deng L, ..., Chen DYK (2009) Synthesis of functionalized maoecrystal V core structures. Chemical
Communications. [IF=0.902, Cited=20, 20024296].
- Nicolaou KC, Hale CRH, Nilewski C, Ioannidou HA (2012) Constructing molecular complexity and diversity: total synthesis
of natural products of biological and medicinal importance. Chemical Society Reviews. [IF=8.116, Cited=47, 22743704].
- Nicolaou KC, Valiulin RA (2013) Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent
antitumor agents. Organic and Biomolecular Chemistry. [IF=0.77, Cited=4, 23685867].
- Fiore S, Nicolaou KC, Caulfield T, ..., Serhan CN (1990) Evaluation of synthetic sphingosine, lysosphingolipids and
glycosphingolipids as inhibitors of functional responses of human neutrophils. Biochemical Journal. [IF=0.852, Cited=8, 2155608].
- Nicolaou KC, Harrison ST, Chen JS (2009) Discoveries from the Abyss: The Abyssomicins and Their Total Synthesis.
Synthesis. [IF=0.648, Cited=12, 20047014].
- Nicolaou KC (2004) The essence of total synthesis. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=40, 15302925].
- Giannakakou P, Gussio R, Nogales E, ..., Fojo T (2000) A common pharmacophore for epothilone and taxanes: molecular
basis for drug resistance conferred by tubulin mutations in human cancer cells. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=223, 10688884].
- Nicolaou KC, Sanchini S, Sarlah D, ..., Burton DR (2011) Design, synthesis, and biological evaluation of a biyouyanagin
compound library. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=17, 21245351].
- Giannakakou P, Nakano M, Nicolaou KC, ..., Fojo T (2002) Enhanced microtubule-dependent trafficking and p53 nuclear
accumulation by suppression of microtubule dynamics. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=128, 12145320].
- Lefer AM, Stahl GL, Lefer DJ, ..., Smith JB (1988) Lipoxins A4 and B4: comparison of icosanoids having
bronchoconstrictor and vasodilator actions but lacking platelet aggregatory activity. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=29, 3186729].
- Nicolaou KC, Smith AL, Yue EW (1993) Chemistry and biology of natural and designed enediynes. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=63, 8327459].
- Maryanoff BE, Qiu X, Padmanabhan KP, ..., Liu A (1993) Molecular basis for the inhibition of human alpha-thrombin by the
macrocyclic peptide cyclotheonamide A. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=31, 8367461].
- Nicolaou KC, Stabila P, Esmaeli-Azad B, ..., Hiatt A (1993) Cell-specific regulation of apoptosis by designed enediynes.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=18, 8475052].
- Liu C, Smith BM, Ajito K, ..., Vogt PK (1996) Sequence-selective carbohydrate-DNA interaction: dimeric and monomeric
forms of the calicheamicin oligosaccharide interfere with transcription factor function. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=18, 8570664].
- LaMarr WA, Yu L, Nicolaou KC, Dedon PC (1998) Supercoiling affects the accessibility of glutathione to DNA-bound
molecules: positive supercoiling inhibits calicheamicin-induced DNA damage. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=9, 9419336].
- Demont-Caulet N, Maillet F, Tailler D, ..., Dénarié J (1999) Nodule-inducing activity of synthetic Sinorhizobium
meliloti nodulation factors and related lipo-chitooligosaccharides on alfalfa. Importance of the acyl chain structure.
Plant Physiology. [IF=1.719, Cited=22, 10318686].
- Nicolaou KC, Dai WM, Tsay SC, ..., Wrasidlo W (1992) Designed enediynes: a new class of DNA-cleaving molecules with
potent and selective anticancer activity. Science. [IF=7.729, Cited=71, 1589797].
- Lefer AM, Ogletree ML, Smith JB, ..., Gasic GP (1978) Prostacyclin: a potentially valuable agent for preserving
myocardial tissue in acute myocardial ischemia. Science. [IF=7.729, Cited=159, 345441].
- Wenzel M, Patra M, Albrecht D, ..., Bandow JE (2011) Proteomic signature of fatty acid biosynthesis inhibition available
for in vivo mechanism-of-action studies. Antimicrobial Agents and Chemotherapy. [IF=1.175, Cited=34, 21383089].
- Narita T, Yin S, Gelin CF, ..., Van Meir EG (2009) Identification of a novel small molecule HIF-1alpha translation
inhibitor. Clinical Cancer Research. [IF=2.156, Cited=79, 19789328].
- Yin S, Kaluz S, Devi NS, ..., Van Meir EG (2012) Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with
HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP. Clinical Cancer Research. [IF=2.156, Cited=52, 22923450].
- Nicolaou KC, Pfefferkorn J, Xu J, ..., Li T (1999) Total synthesis and chemical biology of the sarcodictyins. Chemical
and Pharmaceutical Bulletin. [IF=0.569, Cited=13, 10517002].
- Nicolaou KC, Xu J, Murphy F, ..., Ohshima T (1999) Total Synthesis of Sanglifehrin A. Angewandte Chemie - International
Edition. [IF=2.456, Cited=0, 10458817].
- Nicolaou KC, Mitchell H, Suzuki H, ..., Fylaktakidou K (1999) Total Synthesis of Everninomicin 13,384-1-Part 1:
Synthesis of the A(1)B(A)C Fragment. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 10602188].
- Nicolaou KC, Vourloumis D, Winssinger N, Baran P (2000) The Art and Science of Total Synthesis at the Dawn of the
Twenty-First Century. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 10649349].
- Nicolaou KC, Zhong Y, Baran P (2000) New Synthetic Technology for the Rapid Construction of Novel Heterocycles-Part 1:
The Reaction of Dess - Martin Periodinane with Anilides and Related Compounds. Angewandte Chemie - International
Edition. [IF=2.456, Cited=0, 10671278].
- Nicolaou KC, Pfefferkorn J, Cao G (2000) Selenium-Based Solid-Phase Synthesis of Benzopyrans I: Applications to
Combinatorial Synthesis of Natural Products. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 10760852].
- Nicolaou KC, Cao G, Pfefferkorn J (2000) Selenium-Based Solid-Phase Synthesis of Benzopyrans II: Applications to
Combinatorial Synthesis of Medicinally Relevant Small Organic Molecules. Angewandte Chemie - International Edition.
[IF=2.456, Cited=0, 10760853].
- Nicolaou KC, Snyder S, Bigot A, Pfefferkorn J (2000) Solution and Solid-Phase Synthesis of Functionalized
3-Arylbenzofurans by a Novel Cyclofragmentation - Release Pathway Financial support for this work was provided by The
Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), doctoral fellowships from the National
Science Foundation (S.A.S.) and the Department of Defense (J.A.P.), and grants from Abbott, Amgen, Boehringer -
Ingelheim, Glaxo, Hoffmann - La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 10760931].
- Nicolaou KC, Baran P, Zhong Y, Vega J (2000) Novel IBX-Mediated Processes for the Synthesis of Amino Sugars and
Libraries Thereof We thank Dr. D. H. Huang, Dr. G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric,
and X-ray crystallographic assistance, respectively, and Prof. H. M. R. Hoffmann and Prof. A. Eschenmoser for helpful
discussions. We also thank Dr. Maria-Rosa Rodriguez and Mr. Keith Wilcoxen of these laboratories for early intermediates
leading to 9-12. This work was financially supported by the National Institutes of Health (USA), The Skaggs Institute
for Chemical Biology, fellowships from the Ministerio de Educacion y Cultura, Spain (J.A.V.) and the National Science
Foundation (P.S.B), and grants from Array Biopharma, Pfizer, GlaxoWellcome, Merck, Schering Plough, Hoffmann-LaRoche,
Boehringer Ingelheim, DuPont, and Abbott Laboratories. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 10941125].
- Nicolaou KC, Baran PS, Kranich R, ..., Zou N (2001) Mechanistic Studies of Periodinane-Mediated Reactions of Anilides
and Related Systems Professors M. G. Finn, A. Eschenmoser, and M. E. Newcomb are gratefully acknowledged for valuable
discussions and suggestions. We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric
assistance, respectively. We would also like to thank Dr. G. Vasilikogiannakis for helpful discussions and an anonymous
referee for critical suggestions. Financial support for this work was provided by The Skaggs Institute for Chemical
Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.B.),
postdoctoral fellowships from ArrayBiopharma (N.Z.) and Bayer AG (R.K.), and grants from Abbott, Amgen, ArrayBiopharma,
Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 11169713].
- Nicolaou KC, Sugita K, Baran PS, Zhong YL (2001) New Synthetic Technology for the Construction of N-Containing Quinones
and Derivatives Thereof: Total Synthesis of Epoxyquinomycin B We thank Dr. D. H. Huang, Dr. G. Siuzdak, and Dr. R.
Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support
for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a
predoctoral fellowship from the National Science Foundation (P.B.), and grants from Abbott, Amgen, ArrayBiopharma,
Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 11169714].
- Nicolaou KC, Boddy CNC, Siegel JS (2001) Does CIP Nomenclature Adequately Handle Molecules with Multiple Stereoelements?
A Case Study of Vancomycin and Cognates We would like to thank Professor Dieter Hellwinkel for pointing out to us the
stereochemical discrepancies in our review6 and elsewhere in the literature, and Kurt Mislow for stimulating and useful
discussions. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 11241596].
- Nicolaou KC, Gray D (2001) Total Synthesis of Hybocarpone We thank Dr. D. H. Huang, Dr. G. Siuzdak and Dr. I. Ioannou
for NMR spectroscopic, mass spectrometric and computational assistance, respectively. Financial support for this work
was provided by the Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), and grants from
Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, CaPCURE,
and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 11241615].
- Nicolaou KC, Pihko PM, Diedrichs N, ..., Bernal F (2001) Synthesis of the FGHI Ring System of Azaspiracid We thank Dr.
D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support
for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a
predoctoral fellowship from Bristol-Myers Squibb (F.B.), postdoctoral fellowships from the Academy of Finland, the Ella
and Georg Ehrnrooth Foundation, and the Tauno Tönning Foundation (all to P.M.P.), ArrayBiopharma (N.Z.), and Bayer AG
(N.D.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck,
Novartis, Pfizer, and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 11301444].
- Nicolaou KC, Sugita K, Baran PS, Zhong YL (2001) New Synthetic Technology for the Construction of N-Containing Quinones
and Derivatives Thereof: Total Synthesis of Epoxyquinomycin B We thank Dr. D. H. Huang, Dr. G. Siuzdak, and Dr. R.
Chadha for NMR spectroscopic, mass spectrometric, and X-ray crystallographic assistance, respectively. Financial support
for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a
predoctoral fellowship from the National Science Foundation (P.B.), and grants from Abbott, Amgen, ArrayBiopharma,
Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 11353465].
- Nicolaou KC, Pihko PM, Diedrichs N, ..., Bernal F (2001) Synthesis of the FGHI Ring System of Azaspiracid We thank Dr.
D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support
for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), a
predoctoral fellowship from Bristol-Myers Squibb (F.B.), postdoctoral fellowships from the Academy of Finland, the Ella
and Georg Ehrnrooth Foundation, and the Tauno Tönning Foundation (all to P.M.P.), ArrayBiopharma (N.Z.), and Bayer AG
(N.D.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck,
Novartis, Pfizer, and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 11353466].
- Nicolaou KC, Mitchell HJ (2001) Adventures in Carbohydrate Chemistry: New Synthetic Technologies, Chemical Synthesis,
Molecular Design, and Chemical Biology A list of abbreviations can be found at the end of this article. Telemachos
Charalambous was an inspiring teacher at the Pancyprian Gymnasium, Nicosia, Cyprus. Angewandte Chemie - International
Edition. [IF=2.456, Cited=0, 11353467].
- Nicolaou KC, Zhong YL, Baran PS, Sugita K (2001) Rapid Access to Complex Molecular Architectures via o-Azaquinones We
thank Dr. D. H. Huang, G. Siuzdak, and Dr. R. Chadha for NMR spectroscopic, mass spectrometric, and X-ray
crystallographic assistance, respectively. This work was supported financially by The Skaggs Institute for Chemical
Biology, the National Institutes of Health (USA), a predoctoral fellowship from the National Science Foundation (P.S.B),
and grants from ArrayBiopharma, Pfizer, Glaxo, Merck, Schering Plough, Hoffmann-La Roche, Boehringer Ingelheim, DuPont,
and Abbott Laboratories. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 11433472].
- Nicolaou KC, Vassilikogiannakis G, Mägerlein W, Kranich R (2001) Total Synthesis of Colombiasin A This work was
financially supported by the National Institutes of Health (USA) and The Skaggs Institute for Chemical Biology,
postdoctoral fellowships from Bayer AG (to R.K. and W.M.), and grants from Abbott, Amgen, ArrayBiopharma, Boehringer-
Ingelheim, Glaxo, Hoffmann-La Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 11443672].
- Nicolaou KC, Li Y, Fylaktakidou KC, ..., Weyershausen B (2001) Total Synthesis of Apoptolidin: Part 1. Retrosynthetic
Analysis and Construction of Building Blocks We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass
spectrometric assistance, respectively. This work was financially supported by the National Institutes of Health (USA),
the Skaggs Institute for Chemical Biology, American Biosciences, a pre-doctoral fellowship from Boehringer Ingelheim
(Y.L.), a postdoctoral fellowship the George Hewitt Foundation (K.C.F.), and grants from Abbott Laboratories,
ArrayBiopharma, Bayer, Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering
Plough. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 11668553].
- Nicolaou KC, Li Y, Fylaktakidou KC, ..., Sugita K (2001) Total Synthesis of Apoptolidin: Part 2. Coupling of Key
Building Blocks and Completion of the Synthesis We thank Dr. C. Khosla and Dr. Y. Hayakawa for generous gifts of
apoptolidin, and Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance,
respectively. This work was financially supported by the National Institutes of Health (USA), the Skaggs Institute for
Chemical Biology, American Biosciences, a predoctoral fellowship from Boehringer Ingelheim (to Y.L.), a postdoctoral
fellowship the George Hewitt Foundation (to K.C.F.), and grants from Abbott Laboratories, ArrayBiopharma, Bayer,
Boehringer Ingelheim, DuPont, Glaxo, Hoffmann-LaRoche, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 11668554].
- Nicolaou KC, Qian W, Bernal F, ..., Hinrichs J (2001) Synthesis of the ABCD Ring System of Azaspiracid We thank Drs. D.
H. Huang and G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. This work was financially
supported by the National Institutes of Health (USA), The Skaggs Institute for Chemical Biology, a predoctoral
fellowship from Bristol-Myers Squibb (to F.B.), postdoctoral fellowships from The Skaggs Institute for Research (to
W.Q.), the Academy of Finland, the Ella and Georg Ehrnrooth Foundation and the Tauno Tönning Foundation (all to P.M.P.),
and Bayer AG (to J.H.), as well as grants from Abbott, Amgen, ArrayBiopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-La
Roche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie - International Edition. [IF=2.456,
Cited=0, 12404495].
- Nicolaou KC, Evans RM, Roecker AJ, ..., Pfefferkorn JA (2003) Discovery and optimization of non-steroidal FXR agonists
from natural product-like libraries. Organic and Biomolecular Chemistry. [IF=0.77, Cited=0, 12929628].
- Nicolaou KC, Follmann M, Roecker AJ, Hunt KW (2002) Model studies towards azadirachtin: part 1. Construction of the
crowded C8-C14 bond by radical chemistry. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 19746610].
- Nicolaou KC, Roecker AJ, Follmann M, Baati R (2002) Model studies towards azadirachtin: part 2. Construction of the
crowded C8-C14 bond by transition metal chemistry. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 19746611].
- Nicolaou KC, Safina BS, Funke C, ..., Zécri FJ (2002) Stereocontrolled synthesis of the quinaldic acid macrocyclic
system of thiostrepton. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 19750639].
- Nicolaou KC, Nevalainen M, Safina BS, ..., Bulat S (2002) A biomimetically inspired synthesis of the dehydropiperidine
domain of thiostrepton. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 19750640].
Publication with MISSING institution:
- Xiao XY, Li R, Zhuang H, ..., Nicolaou KC (2000) Solid-phase combinatorial synthesis using MicroKan reactors, Rf
tagging, and directed sorting. Biotechnology and Bioengineering. [IF=0.932, Cited=13, 10629535].
- Nicolaou KC, Gasic GP, Barnette WE (1978) Synthesis and biological properties of prostaglandin endoperoxides,
thromboxanes and prostacyclins. Angewandte Chemie - International Edition. [IF=2.456, Cited=9, 98074].
- Cee VJ, Chen DYK, Lee MR, Nicolaou KC (2009) Cortistatin A is a high-affinity ligand of protein kinases ROCK, CDK8, and
CDK11. Angewandte Chemie - International Edition. [IF=2.456, Cited=48, 19844931].
- Nicolaou KC, Rigol S (2021) Corrigendum: The Role of Organic Synthesis in the Emergence and Development of Antibody-Drug
Conjugates as Targeted Cancer Therapies. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 34312957].
- Frederick MO, De Lamo Marin S, Janda KD, ..., Dickerson TJ (2009) Monoclonal antibodies with orthogonal azaspiracid
epitopes. ChemBioChem. [IF=0.691, Cited=8, 19492388].
- Bunnage ME, Nicolaou KC (1997) The oxide anion accelerated retro-diels-alder reaction. Chemistry - A European Journal.
[IF=0.899, Cited=4, 24022946].
- Altmann KH, Pfeiffer B, Arseniyadis S, ..., Nicolaou KC (2007) The chemistry and biology of epothilones--the wheel keeps
turning. ChemMedChem. [IF=0.766, Cited=43, 17340668].
- Vale C, Wandscheer C, Nicolaou KC, ..., Botana LM (2008) Cytotoxic effect of azaspiracid-2 and azaspiracid-2-methyl
ester in cultured neurons: involvement of the c-Jun N-terminal kinase. Journal of Neuroscience Research. [IF=1.0,
Cited=5, 18500761].
- Webber SE, Webber SE, Veale CA, Nicolaou KC (1988) The total synthesis of the lipoxins and related compounds. Advances
in Experimental Medicine and Biology. [IF=0.945, Cited=0, 3421158].
- Lefer AM, Smith JB, Nicolaou KC (1981) Thromboxane synthetase inhibitors differentially antagonize thromboxane receptors
in vascular smooth muscle. Naunyn-Schmiedeberg's Archives of Pharmacology. [IF=0.838, Cited=0, 6276789].
- Gryglewski RJ, Nicolaou KC (1978) A triple test for screening biological activity of prostacyclin analogues. None.
[IF=None, Cited=5, 367809].
- Wikström E, Westlund P, Nicolaou KC, Dahlén SE (1989) Lipoxin A4 causes generation of thromboxane A2 in the guinea-pig
lung. None. [IF=None, Cited=5, 2711953].
- Dahlén SE, Veale CA, Webber SE, ..., Serhan CN (1989) Pharmacodynamics of lipoxin A4 in airway smooth muscle. None.
[IF=None, Cited=6, 2711954].
- Ferreiro SF, Vilariño N, Carrera C, ..., Botana LM (2013) In vivo arrhythmogenicity of the marine biotoxin azaspiracid-2
in rats. Archives of Toxicology. [IF=1.533, Cited=11, 23934164].
- Newman RA, Yang J, Raymond M, ..., Navone NM (2001) Antitumor efficacy of 26-fluoroepothilone B against human prostate
cancer xenografts. Cancer Chemotherapy and Pharmacology. [IF=0.809, Cited=21, 11710633].
- Manku MS, Horrobin DF, Cunnane SC, ..., Barnette WE (1978) Prostaglandins E1, E2 and I2: evidence for three distinct
actions in vascular smooth muscle. Biochemical and Biophysical Research Communications. [IF=0.643, Cited=15, 358978].
- Palmblad J, Gyllenhammar H, Ringertz B, ..., Nicolaou KC (1987) The effects of lipoxin A and lipoxin B on functional
responses of human granulocytes. Biochemical and Biophysical Research Communications. [IF=0.643, Cited=18, 3593338].
- Badr KF, Serhan CN, Nicolaou KC, Samuelsson B (1987) The action of lipoxin-A on glomerular microcirculatory dynamics in
the rat. Biochemical and Biophysical Research Communications. [IF=0.643, Cited=20, 3593345].
- Luscinskas FW, Nicolaou KC, Webber SE, ..., Serhan CN (1990) Ca2+ mobilization with leukotriene A4 and epoxytetraenes in
human neutrophils. Biochemical Pharmacology. [IF=1.155, Cited=12, 2154229].
- Ogletree ML, Lefer AM, Smith JB, Nicolaou KC (1979) Studies on the protective effect of prostacyclin in acute myocardial
ischemia. European Journal of Pharmacology. [IF=1.015, Cited=104, 467518].
- Stahl GL, Tsao P, Lefer AM, ..., Nicolaou KC (1989) Pharmacologic profile of lipoxins A5 and B5: new biologically active
eicosanoids. European Journal of Pharmacology. [IF=1.015, Cited=6, 2545463].
- Koshishara Y, Murota S, Petasis NA, Nicolaou KC (1982) Selective inhibition of 5-lipoxygenase by 5,6-methanoleukotriene
A4, a stable analogue of leukotriene A4. FEBS Letters. [IF=0.871, Cited=13, 6811315].
- Puustinen T, Webber SE, Webber SE, ..., Samuelsson B (1986) Evidence for a 5(6)-epoxytetraene intermediate in the
biosynthesis of lipoxins in human leukocytes. Conversion into lipoxin A by cytosolic epoxide hydrolase. FEBS Letters.
[IF=0.871, Cited=13, 3770188].
- Brezinski ME, Gimbrone MA, Nicolaou KC, Serhan CN (1989) Lipoxins stimulate prostacyclin generation by human endothelial
cells. FEBS Letters. [IF=0.871, Cited=46, 2494071].
- Karazyn M, Horrobin DF, Manku MS, ..., Barnette WE (1978) Effect of prostacyclin on perfusion pressure, electrical
activity, rate and force of contraction in isolated rat and rabbit hearts. Life Sciences. [IF=1.121, Cited=22, 353421].
- Lefer AM, Trachte GJ, Smith JB, ..., Nicolaou KC (1979) Circulatory and platelet actions of 6,9-thiaprostacyclin
(PGI2-S) in the cat. Life Sciences. [IF=1.121, Cited=4, 384128].
- Smith JB, Lefer AM, Nicolaou KC (1981) Spasmogenic effects of the anti-fertility agent, zoapatanol. Life Sciences.
[IF=1.121, Cited=10, 7266247].
- Nicolaou KC, Magolda RL (1982) Synthesis of stable thromboxane A2 analogs: pinane thromboxane A2 (PTA2) and carbocyclic
thromboxane A2 (CTA2). None. [IF=None, Cited=1, 7132765].
- Pace-Asciak CR, Carrara MC, Nicolaou KC (1978) Prostaglandin I2 has more potent hypotensive properties than
prostaglandin E2 in the normal and spontaneously hypertensive rat. None. [IF=None, Cited=40, 358298].
- Pace-Asciak CR, Carrara MC, Rangaraj G, Nicolaou KC (1978) Enhanced formation of PGI2, a potent hypotensive substance,
by aortic rings and homogenates of the spontaneously hypertensive rat. None. [IF=None, Cited=95, 358292].
- Komoriya K, Ohmori H, Azuma A, ..., Magolda RL (1978) Prostaglandin I2 as a potentiator of acute inflammation in rats.
None. [IF=None, Cited=27, 353901].
- Hawkings HJ, Smith JB, Nicolaou KC, Eling TE (1978) Studies of the mechanisms involved in the fate of prostacyclin
(PGI2) and 6-keto-PGF1alpha in the pulmonary circulation. None. [IF=None, Cited=22, 219443].
- Raisz LG, Vanderhoek JY, Simmons HA, ..., Nicolaou KC (1979) Prostaglandin synthesis by fetal rat bone in vitro:
evidence for a role of prostacyclin. None. [IF=None, Cited=99, 388530].
- Pace-Asciak CR, Carrara MC, Levine L, Nicolaou KC (1980) PGI2-specific antibodies administered in vivo suggest against a
role for endogenous PGI2 as a circulating vasodepressor hormone in the normotensive and spontaneously hypertensive rat.
None. [IF=None, Cited=14, 7010446].
- Lefer AM, Aharony D, Smith JB, ..., Nicolaou KC (1981) Carbocyclic thromboxane A2: aggrevation of myocardial ischemia by
a new synthetic thromboxane A2 analog. None. [IF=None, Cited=24, 7232768].
- Smith JB, Roth DM, Lefer AM, ..., Nicolaou KC (1985) Modulation of leukotriene synthesis and actions by synthetic
derivatives of arachidonic acid. None. [IF=None, Cited=3, 4011927].
- Yanagisawa A, Lefer AM, Elisseou EM, Nicolaou KC (1986) Synthesis and vascular actions of an arachidonic acid ethylene-
diamino-triethyl-ester (AA-EDTA) derivative. None. [IF=None, Cited=1, 3094093].
- Tsai BS, Keith RH, Villani-Price D, ..., Nicolaou KC (1989) Differential effects of 20-trifluoromethyl leukotriene B4 on
human neutrophil functions. None. [IF=None, Cited=6, 2543037].
- Nicolaou KC, Barnette WE, Magolda RL (1978) Synthesis of prostaglandin H2 (PGH2) and prostacyclin (PGI2) analogs:
tetrathia-PGH2 and PGI2-ketal methyl ester. None. [IF=None, Cited=1, 362454].
- Lefer AM, Araki H, Smith JB, ..., Magolda RL (1979) Protective effects of a novel thromboxane analog in lethal traumatic
shock. None. [IF=None, Cited=8, 552102].
- Gullner HG, Nicolaou KC, Bartter FC (1980) Prostacyclin has effects on proximal and distal tubular function in the dog.
None. [IF=None, Cited=3, 6994154].
- Roth DM, Lefer AM, Smith JB, Nicolaou KC (1982) Anti-thromboxane A2 actions of pinane thromboxane A2 derivatives. None.
[IF=None, Cited=1, 6960376].
- Yanagisawa A, Brezinski M, Lefer AM, ..., Nicolaou KC (1986) Coronary vasoactivity of four 7,13-bridged analogs of
arachidonic acid. None. [IF=None, Cited=2, 3090560].
- Gomez Paloma L, Guy RK, Wrasidlo W, Nicolaou KC (1994) Conformation of a water-soluble derivative of taxol in water by
2D-NMR spectroscopy. None. [IF=None, Cited=24, 9383378].
- Chakraborty TK, Weber HP, Nicolaou KC (1995) Design and synthesis of a rapamycin-based high affinity binding FKBP12
ligand. None. [IF=None, Cited=8, 9383417].
- Koide K, Bunnage ME, Gomez Paloma L, ..., Nicolaou KC (1995) Molecular design and biological activity of potent and
selective protein kinase inhibitors related to balanol. None. [IF=None, Cited=21, 9383464].
- Gawley RE, Rein KS, Jeglitsch G, ..., Baden DG (1995) The relationship of brevetoxin 'length' and A-ring functionality
to binding and activity in neuronal sodium channels. None. [IF=None, Cited=49, 9383457].
- Alfonso A, Vieytes MR, Ofuji K, ..., Botana LM (2006) Azaspiracids modulate intracellular pH levels in human
lymphocytes. Biochemical and Biophysical Research Communications. [IF=0.643, Cited=10, 16793022].
- Vilariño N, Nicolaou KC, Frederick MO, ..., Botana LM (2007) Irreversible cytoskeletal disarrangement is independent of
caspase activation during in vitro azaspiracid toxicity in human neuroblastoma cells. Biochemical Pharmacology.
[IF=1.155, Cited=19, 17485074].
- Tan C, de Noronha RG, Devi NS, ..., Van Meir EG (2011) Sulfonamides as a new scaffold for hypoxia inducible factor
pathway inhibitors. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=19, 21831638].
- Mishra OP, Simmons N, Tyagi S, ..., Christofidou-Solomidou M (2013) Synthesis and antioxidant evaluation of (S,S)- and
(R,R)-secoisolariciresinol diglucosides (SDGs). Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=27, 23978651].
- Buey RM, Díaz JF, Andreu JM, ..., Namoto K (2004) Interaction of epothilone analogs with the paclitaxel binding site:
relationship between binding affinity, microtubule stabilization, and cytotoxicity. None. [IF=None, Cited=56, 15123284].
- Starosta AL, Qin H, Mikolajka A, ..., Wilson DN (2009) Identification of distinct thiopeptide-antibiotic precursor lead
compounds using translation machinery assays. None. [IF=None, Cited=17, 19875082].
- Jeso V, Nicolaou KC (2009) Total Synthesis of Tovophyllin B. Tetrahedron Letters. [IF=0.515, Cited=5, 20161287].
- Nicolaou KC, Bernette WE, Gasic BP, ..., Ingerman CM (1977) Rapid and easy preparation of prostacyclin. The Lancet.
[IF=25.787, Cited=11, 67522].
- Nicholas GM, Eckman LL, Ray S, ..., Bewley CA (2002) Bromotyrosine-derived natural and synthetic products as inhibitors
of mycothiol-S-conjugate amidase. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=35, 12161164].
- Downes M, Verdecia MA, Roecker AJ, ..., Evans RM (2003) A chemical, genetic, and structural analysis of the nuclear bile
acid receptor FXR. Molecular Cell. [IF=2.773, Cited=217, 12718892].
- Nicolaou KC, Pulukuri KK, Rigol S, ..., Gavrilyuk J (2019) Correction to "Short Total Synthesis of
Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of
Macrocyclic Δ12-Prostaglandin J2 Analogues". Journal of Organic Chemistry. [IF=0.885, Cited=1, 30715889].
- Nicolaou KC, Ladduwahetty T, Randall JL, Chucholowski A (1986) Stereospecific 1,2-migrations in carbohydrates.
Stereocontrolled synthesis of .alpha.- and .beta.-2-deoxyglycosides. Journal of the American Chemical Society.
[IF=2.573, Cited=31, 22175613].
- Nicolaou KC, Duggan ME, Hwang CK (1986) New synthetic technology for the construction of oxocenes. Journal of the
American Chemical Society. [IF=2.573, Cited=13, 22175614].
- Nicolaou KC, Baran PS, Zhong YL (2001) Selective oxidation at carbon adjacent to aromatic systems with IBX. Journal of
the American Chemical Society. [IF=2.573, Cited=22, 11457049].
- Nicolaou KC, Barnette WE, Gasic GP, Magolda RL (1977) 6,9-thiaprostacyclin. A stable and biologically potent analogue of
prostacyclin (PGI2). Journal of the American Chemical Society. [IF=2.573, Cited=14, 334822].
- Cory EJ, Nicolaou KC, Melvin LS (1975) Letter: Synthesis of novel macrocyclic lactones in the prostaglandin and
polyether antibiotic series. Journal of the American Chemical Society. [IF=2.573, Cited=14, 1133366].
- Corey EJ, Corey EJ, Nicolaou KC, Toru T (1975) Letter: Total synthesis of (plus or minus)-vermiculine. Journal of the
American Chemical Society. [IF=2.573, Cited=11, 1133413].
- Nicolaou KC, Nilewski C, Hale CRH, ..., Nagrath D (2015) Synthesis and biological evaluation of dimeric furanoid
macroheterocycles: discovery of new anticancer agents. Journal of the American Chemical Society. [IF=2.573, Cited=2, 25827338].
- Nicolaou KC, Li R, Lu Z, ..., Gavrilyuk J (2018) Streamlined Total Synthesis of Shishijimicin A and Its Application to
the Design, Synthesis, and Biological Evaluation of Analogues thereof and Practical Syntheses of PhthNSSMe and Related
Sulfenylating Reagents. Journal of the American Chemical Society. [IF=2.573, Cited=8, 30216054].
- Li T, Nicolaou KC (1994) Chemical self-replication of palindromic duplex DNA. Nature. [IF=11.591, Cited=85, 8183341].
- Nicolaou KC, Guy RK, Potier P (1996) Taxoids: new weapons against cancer. None. [IF=None, Cited=21, 8643952].
- Bono JJ, Riond J, Nicolaou KC, ..., Ranjeva R (1995) Characterization of a binding site for chemically synthesized lipo-
oligosaccharidic NodRm factors in particulate fractions prepared from roots. Plant Journal. [IF=1.71, Cited=45, 7704048].
- Nicolaou KC (2004) The art and science of constructing the molecules of nature. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=2, 16576760].
- Corey EJ, Corey EJ, Nicolaou KC, ..., Samuelsson B (1975) Synthesis and biological properties of a 9,11-azo-prostanoid:
highly active biochemical mimic of prostaglandin endoperoxides. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=42, 1059121].
- Nicolaou KC, Magolda RL, Smith JB, ..., Lefer AM (1979) Synthesis and biological properties of pinane-thromboxane A2, a
selective inhibitor of coronary artery constriction, platelet aggregation, and thromboxane formation. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=27, 288046].
- Lefer AM, Araki H, Smith JB, ..., Nicolaou KC (1980) Dissociation of vasoconstrictor and platelet aggregatory activities
of thromboxane by carbocyclic thromboxane A2, a stable analog of thromboxane A2. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=42, 6929517].
- Green PJ, Yuen CT, Childs RA, ..., Nicolaou KC (1995) Further studies of the binding specificity of the leukocyte
adhesion molecule, L-selectin, towards sulphated oligosaccharides--suggestion of a link between the selectin- and the
integrin-mediated lymphocyte adhesion systems. Glycobiology. [IF=0.962, Cited=32, 7539644].
- Vale C, Nicolaou KC, Frederick MO, ..., Botana LM (2009) Cell volume decrease as a link between azaspiracid-induced
cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. Toxicological Sciences. [IF=0.949, Cited=10, 19815690].
- Cao Z, LePage KT, Frederick MO, ..., Murray TF (2010) Involvement of caspase activation in azaspiracid-induced
neurotoxicity in neocortical neurons. Toxicological Sciences. [IF=0.949, Cited=21, 20047973].
- Burke SE, Lefer AM, Nicolaou KC, ..., Smith JB (1983) Responsiveness of platelets and coronary arteries from different
species to synthetic thromboxane and prostaglandin endoperoxide analogues. British Journal of Pharmacology. [IF=1.816,
Cited=65, 6831115].
- Hedqvist P, Raud J, Palmertz U, ..., Dahlén SE (1989) Lipoxin A4 inhibits leukotriene B4-induced inflammation in the
hamster cheek pouch. None. [IF=None, Cited=46, 2557732].
- Hamel E, Day BW, Miller JH, ..., Sorensen EJ (2006) Synergistic effects of peloruside A and laulimalide with taxoid site
drugs, but not with each other, on tubulin assembly. Molecular Pharmacology. [IF=0.939, Cited=63, 16887932].
- Setyawan J, Koide K, Diller TC, ..., Brunton LL (1999) Inhibition of protein kinases by balanol: specificity within the
serine/threonine protein kinase subfamily. Molecular Pharmacology. [IF=0.939, Cited=21, 10419556].
- Koppaka V, Thompson DC, Chen Y, ..., Vasiliou V (2012) Aldehyde dehydrogenase inhibitors: a comprehensive review of the
pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacological Reviews. [IF=4.608,
Cited=281, 22544865].
- Cunnane SC, Zinner H, Horrobin DF, ..., Nicolaou KC (1979) Copper inhibits pressor responses to noradrenaline but not
potassium. Interactions with prostaglandins E1, E2, and I2 and penicillamine. Canadian Journal of Physiology and
Pharmacology. [IF=0.544, Cited=10, 371766].
- Schrör K, Bickerton M, Smith JB, ..., Lefer AM (1980) Preservation of ischemic myocardium by pinane thromboxane A2.
None. [IF=None, Cited=34, 7356037].
- Lefer AM, Nicolaou KC (1981) Mechanism of coronary vasoconstriction induced by carbocyclic thromboxane A2. None.
[IF=None, Cited=35, 6261592].
- Vale C, Gómez-Limia B, Nicolaou KC, ..., Botana LM (2007) The c-Jun-N-terminal kinase is involved in the neurotoxic
effect of azaspiracid-1. Cellular Physiology and Biochemistry. [IF=0.848, Cited=11, 17982278].
- Güllner HG, Nicolaou KC, Bartter FC, Kelly G (1980) Effect of prostacyclin (PGI2) on renal function and renin secretion
in hypophysectomized dogs. None. [IF=None, Cited=7, 6993967].
- Webber PC, Larsson C, Anggard E, ..., Samuelsson B (1976) Stimulation of renin release from rabbit renal cortex by
arachidonic acid and prostaglandin endoperoxides. Circulation Research. [IF=3.534, Cited=104, 1000781].
- Lee TH, Crea AE, Gant V, ..., Serhan CN (1990) Identification of lipoxin A4 and its relationship to the sulfidopeptide
leukotrienes C4, D4, and E4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary
diseases. None. [IF=None, Cited=80, 2161628].
- Needleman P, Bronson SD, Wyche A, ..., Nicolaou KC (1978) Cardiac and renal prostaglandin I2. Biosynthesis and
biological effects in isolated perfused rabbit tissues. Journal of Clinical Investigation. [IF=2.423, Cited=101, 346605].
- Siegl AM, Smith JB, Silver MJ, ..., Ahern D (1979) Selective binding site for [3H]prostacyclin on platelets. Journal of
Clinical Investigation. [IF=2.423, Cited=117, 372237].
- Komoriya K, Ohmori H, Azuma A, ..., Nicolaou KC (1979) Effect of 6,9-thia prostaglandin I2 (a stable PGI2 analogue) on
passive cutaneous anaphylaxis (PCA) in rats. None. [IF=None, Cited=0, 395349].
- Wrasidlo W, Hiatt A, Mauch S, ..., Nicolaou KC (1995) In vivo efficacy of novel synthetic enediynes 1. Acta Oncologica.
[IF=1.127, Cited=2, 7718252].
- Bocci G, Nicolaou KC, Kerbel RS (2002) Protracted low-dose effects on human endothelial cell proliferation and survival
in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Research. [IF=1.624,
Cited=0, 12460910].
- Nicolaou KC (2003) Profile. K. C. Nicolaou. Organic and Biomolecular Chemistry. [IF=0.77, Cited=0, 12929625].
- Wikström E, Westlund P, Nicolaou KC, Dahlén SE (1992) Lipoxin A4-induced release of thromboxane in the guinea-pig lung:
studies of its characteristics using lipoxin A4-methyl ester. None. [IF=None, Cited=0, 1467461].
- Tan C, de Noronha RG, Roecker AJ, ..., Van Meir EG (2005) Identification of a novel small-molecule inhibitor of the
hypoxia-inducible factor 1 pathway. Cancer Research. [IF=1.624, Cited=0, 15695405].
- Tsao PS, Stahl GA, Lefer AM, ..., Nicolaou KC (1989) Platelet-activating factor (PAF) antagonistic actions of two new
analogs of tetrahydrofurans. None. [IF=None, Cited=0, 2519893].
- Serhan CN, Nicolaou KC, Webber SE, ..., Samuelsson B (1987) Stereochemistry and biosynthesis of lipoxins. None.
[IF=None, Cited=0, 2959121].
- Serhan CN, Nicolaou KC, Webber SE, ..., Samuelsson B (1986) Lipoxin A. Stereochemistry and biosynthesis. Journal of
Biological Chemistry. [IF=1.122, Cited=0, 3097008].
- Ally AI, Barrette WE, Cunnane S, ..., Nicolaou KC (1978) Prostaglandin I2 (prostacyclin) inhibits intracellular calcium
release [proceedings]. Journal of Physiology. [IF=1.417, Cited=0, 349134].
- Addonizio VP, Macarak J, Nicolaou KC, ..., Colman RW (1979) Effects of prostacyclin and albumin on platelet loss during
in vitro simulation of extracorporeal circulation. Blood. [IF=2.983, Cited=0, 375998].
- Ramstedt U, Serhan CN, Nicolaou KC, ..., Samuelsson B (1987) Lipoxin A-induced inhibition of human natural killer cell
cytotoxicity: studies on stereospecificity of inhibition and mode of action. Journal of Immunology. [IF=0.939, Cited=0, 3782800].
- Ohtsu A, Hoshina K, Kurozumi S, ..., Nicolaou KC (1979) Effects of PGI2 on platelet aggregation induced by various
stimulants. None. [IF=None, Cited=0, 388963].
- Musial J, Niewiarowski S, Edmunds LH, ..., Colman RW (1980) In vivo release and turnover of secreted platelet
antiheparin proteins in rhesus monkey (Macaca mulatta). Blood. [IF=2.983, Cited=0, 6158350].
- Koshihara Y, Murota S, Nicolaou KC (1983) 5,6-methano leukotriene A4: a potent specific inhibitor for 5-lipoxygenase.
None. [IF=None, Cited=0, 6221521].
- Nicolaou KC, Magolda RL, Claremon DA (1980) Synthesis of thromboxane A2 analogs. None. [IF=None, Cited=0, 6992537].
- Araki H, Lefer AM, Smith JB, ..., Magolda R (1980) Beneficial actions of a new thromboxane analog in traumatic shock.
None. [IF=None, Cited=0, 7369045].
- Yuen CT, Bezouska K, O'Brien J, ..., Nicolaou KC (1994) Sulfated blood group Lewis(a). A superior oligosaccharide ligand
for human E-selectin. Journal of Biological Chemistry. [IF=1.122, Cited=0, 7507478].
- Corbeil J, Richman DD, Wrasidlo W, ..., Looney DJ (1994) Antiproliferative effects of enediynes on AIDS-derived Kaposi's
sarcoma cells. Cancer Research. [IF=1.624, Cited=0, 8044770].
- Lode HN, Reisfeld RA, Handgretinger R, ..., Wrasidlo W (1998) Targeted therapy with a novel enediyene antibiotic
calicheamicin theta(I)1 effectively suppresses growth and dissemination of liver metastases in a syngeneic model of
murine neuroblastoma. Cancer Research. [IF=1.624, Cited=0, 9679947].