Modrich, Paul

Publication with MATCHING institution:

Modrich P (2016) Mechanisms in E. coli and Human Mismatch Repair (Nobel Lecture). Angewandte Chemie - International
Edition. [IF=2.456, Cited=49, 27198632].
Bjornson KP, Allen DJ, Modrich P (2000) Modulation of MutS ATP hydrolysis by DNA cofactors. Biochemistry. [IF=0.753,
Cited=60, 10715140].
Iyer RR, Pluciennik A, Burdett V, Modrich P (2006) DNA mismatch repair: functions and mechanisms. Chemical Reviews.
[IF=11.712, Cited=547, 16464007].
Pluciennik A, Modrich P (2007) Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch
repair. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=51, 17620611].
Nimonkar AV, Ozsoy AZ, Genschel J, ..., Kowalczykowski SC (2008) Human exonuclease 1 and BLM helicase interact to resect
DNA and initiate DNA repair. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=206, 18971343].
Kadyrov FA, Genschel J, Fang Y, ..., Modrich P (2009) A possible mechanism for exonuclease 1-independent eukaryotic
mismatch repair. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=98, 19420220].
van Oers JMM, Roa S, Werling U, ..., Edelmann W (2010) PMS2 endonuclease activity has distinct biological functions and
is essential for genome maintenance. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=42, 20624957].
Pluciennik A, Dzantiev L, Iyer RR, ..., Modrich P (2010) PCNA function in the activation and strand direction of MutLα
endonuclease in mismatch repair. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=172, 20713735].
Burdett V, Baitinger C, Viswanathan M, ..., Modrich P (2001) In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in
methyl-directed mismatch repair. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=134, 11381137].
Pluciennik A, Burdett V, Baitinger C, ..., Modrich P (2013) Extrahelical (CAG)/(CTG) triplet repeat elements support
proliferating cell nuclear antigen loading and MutLα endonuclease activation. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=49, 23840062].
Qiu R, Sakato M, Sacho EJ, ..., Weninger KR (2015) MutL traps MutS at a DNA mismatch. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=35, 26283381].
Genschel J, Kadyrova LY, Iyer RR, ..., Modrich P (2017) Interaction of proliferating cell nuclear antigen with PMS2 is
required for MutLα activation and function in mismatch repair. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=27, 28439008].
Sherrer SM, Penland E, Modrich P (2018) The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-
dependent MutLα endonuclease. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=8, 29941579].
Kadyrova LY, Gujar V, Burdett V, ..., Kadyrov FA (2020) Human MutLγ, the MLH1-MLH3 heterodimer, is an endonuclease that
promotes DNA expansion. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=36, 32015124].
Chen S, Bigner SH, Modrich P (2001) High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=22, 11717437].
Au KG, Cabrera M, Miller JH, Modrich P (1988) Escherichia coli mutY gene product is required for specific A-G----C.G
mismatch correction. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=92, 3057502].
Au KG, Clark S, Miller JH, Modrich P (1989) Escherichia coli mutY gene encodes an adenine glycosylase active on G-A
mispairs. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=128, 2682664].
Holmes J, Clark S, Modrich P (1990) Strand-specific mismatch correction in nuclear extracts of human and Drosophila
melanogaster cell lines. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=236, 2116007].
Worth L, Clark S, Radman M, Modrich P (1994) Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand
transfer between diverged DNAs. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=162, 8159731].
Dong Q, Barsky D, Colvin ME, ..., Friedman HS (1995) A structural basis for a phosphoramide mustard-induced DNA
interstrand cross-link at 5'-d(GAC). Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=34, 8618865].
Li GM, Modrich P (1995) Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer
of human MutL homologs. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=228, 7892206].
Duckett DR, Drummond JT, Murchie AI, ..., Modrich P (1996) Human MutSalpha recognizes damaged DNA base pairs containing
O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=243, 8692834].
Smith J, Modrich P (1996) Mutation detection with MutH, MutL, and MutS mismatch repair proteins. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=37, 8633074].
Smith J, Modrich P (1997) Removal of polymerase-produced mutant sequences from PCR products. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=32, 9192654].
Drummond JT, Genschel J, Wolf E, Modrich P (1997) DHFR/MSH3 amplification in methotrexate-resistant cells alters the
hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair. Proceedings of the National Academy
of Sciences of the United States of America. [IF=2.765, Cited=108, 9294177].
Duckett DR, Bronstein SM, Taya Y, Modrich P (1999) hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in
response to DNA methylator damage. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=111, 10535931].
Modrich P (1997) Strand-specific mismatch repair in mammalian cells. Journal of Biological Chemistry. [IF=1.122,
Cited=126, 9312062].
Modrich P (2006) Mechanisms in eukaryotic mismatch repair. Journal of Biological Chemistry. [IF=1.122, Cited=274, 16905530].
Pukkila PJ, Peterson J, Herman G, ..., Meselson M (1983) Effects of high levels of DNA adenine methylation on methyl-
directed mismatch repair in Escherichia coli. Genetics. [IF=1.102, Cited=181, 6225697].
Shao H, Baitinger C, Soderblom EJ, ..., Modrich P (2014) Hydrolytic function of Exo1 in mammalian mismatch repair.
Nucleic Acids Research. [IF=4.663, Cited=19, 24829455].
Modrich P (1995) Mismatch repair, genetic stability and tumour avoidance. Philosophical Transactions of the Royal
Society B: Biological Sciences. [IF=1.629, Cited=26, 7746860].
Lahue RS, Au KG, Modrich P (1989) DNA mismatch correction in a defined system. Science. [IF=7.729, Cited=321, 2665076].
Drummond JT, Li GM, Longley MJ, Modrich P (1995) Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch
repair to tumor cells. Science. [IF=7.729, Cited=337, 7604264].
Modrich P (1994) Mismatch repair, genetic stability, and cancer. Science. [IF=7.729, Cited=222, 7801122].
Mu D, Tursun M, Duckett DR, ..., Sancar A (1997) Recognition and repair of compound DNA lesions (base damage and
mismatch) by human mismatch repair and excision repair systems. Molecular and Cellular Biology. [IF=1.026, Cited=107, 9001230].
Nicolaides NC, Littman SJ, Modrich P, ..., Vogelstein B (1998) A naturally occurring hPMS2 mutation can confer a
dominant negative mutator phenotype. Molecular and Cellular Biology. [IF=1.026, Cited=58, 9488480].
Dowhan W, Nikaido H, Stubbe J, ..., Modrich P (2013) Christian Raetz: scientist and friend extraordinaire. Annual Review
of Biochemistry. [IF=5.273, Cited=3, 23472605].
Modrich P, Lahue R (1996) Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annual
Review of Biochemistry. [IF=5.273, Cited=860, 8811176].
Modrich P (1991) Mechanisms and biological effects of mismatch repair. Annual Review of Genetics. [IF=2.79, Cited=511, 1812808].
Cheng CL, Johnson SP, Keir ST, ..., Friedman HS (2005) Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide
resistance in a DNA mismatch repair-deficient malignant glioma xenograft. Molecular Cancer Therapeutics. [IF=1.04,
Cited=98, 16170028].
Modrich P (1989) Methyl-directed DNA mismatch correction. Journal of Biological Chemistry. [IF=1.122, Cited=157, 2651430].
Lindahl T, Modrich P, Sancar A (2016) The 2015 Nobel Prize in Chemistry The Discovery of Essential Mechanisms that
Repair DNA Damage. None. [IF=None, Cited=10, 27183258].
Modrich P (1995) A human protein with antimutator activity. None. [IF=None, Cited=0, 7730133].

Publication with MISSING institution:

Allison DP, Kerper PS, Doktycz MJ, ..., Warmack RJ (1997) Mapping individual cosmid DNAs by direct AFM imaging.
Genomics. [IF=1.012, Cited=21, 9169135].
Modrich P (1986) Mismatch correction. None. [IF=None, Cited=3, 2943263].
Hanley ML, Elion GB, Colvin OM, ..., Friedman HS (1998) Therapeutic efficacy of vinorelbine against pediatric and adult
central nervous system tumors. Cancer Chemotherapy and Pharmacology. [IF=0.809, Cited=8, 9788574].
Dong Q, Johnson SP, Colvin OM, ..., Friedman HS (1999) Multiple DNA repair mechanisms and alkylator resistance in the
human medulloblastoma cell line D-283 Med (4-HCR). Cancer Chemotherapy and Pharmacology. [IF=0.809, Cited=7, 9923544].
Friedman HS, Pegg AE, Johnson SP, ..., Colvin OM (1999) Modulation of cyclophosphamide activity by O6-alkylguanine-DNA
alkyltransferase. Cancer Chemotherapy and Pharmacology. [IF=0.809, Cited=18, 9923545].
Chintagumpala MM, Friedman HS, Stewart CF, ..., Horowitz ME (2006) A phase II window trial of procarbazine and topotecan
in children with high-grade glioma: a report from the children's oncology group. Journal of Neuro-Oncology. [IF=1.338,
Cited=10, 16314955].
Konrad EB, Modrich P, Lehman IR (1973) Genetic and enzymatic characterization of a conditional lethal mutant of
Escherichia coli K12 with a temperature-sensitive DNA ligase. Journal of Molecular Biology. [IF=1.281, Cited=88, 4353283].
Konrad EB, Modrich P, Lehman IR (1974) DNA synthesis in strains of Escherichia coli K12 with temperature-sensitive DNA
ligase and DNA polymerase I. Journal of Molecular Biology. [IF=1.281, Cited=11, 4616094].
Young T, Kim S, Modrich P, ..., Jay E (1981) Preliminary x-ray diffraction studies of EcoRI restriction endonuclease-DNA
complex. Journal of Molecular Biology. [IF=1.281, Cited=10, 6267292].
Lahue RS, Modrich P (1988) Methyl-directed DNA mismatch repair in Escherichia coli. Mutation Research - Fundamental and
Molecular Mechanisms of Mutagenesis. [IF=0.498, Cited=19, 3280983].
Parsons R, Li GM, Longley MJ, ..., Modrich P (1993) Hypermutability and mismatch repair deficiency in RER+ tumor cells.
Cell. [IF=8.479, Cited=588, 8261516].
Jhon NI, Casas-Finet JR, Maki AH, Modrich P (1988) Investigation of the complexes of EcoRI endonuclease with
decanucleotides containing canonical and modified recognition sequences using fluorescence and optical detection of
magnetic resonance spectroscopy. None. [IF=None, Cited=2, 2829965].
Rebbe NF, Ware J, Bertina RM, ..., Stafford DW (1987) Nucleotide sequence of a cDNA for a member of the human 90-kDa
heat-shock protein family. Gene. [IF=0.932, Cited=105, 3301534].
Grilley M, Holmes J, Yashar B, Modrich P (1990) Mechanisms of DNA-mismatch correction. Mutation Research - Fundamental
and Molecular Mechanisms of Mutagenesis. [IF=0.498, Cited=44, 2144613].
Genschel J, Modrich P (2006) Analysis of the excision step in human DNA mismatch repair. None. [IF=None, Cited=12, 16793375].
Kadyrov FA, Dzantiev L, Constantin N, Modrich P (2006) Endonucleolytic function of MutLalpha in human mismatch repair.
Cell. [IF=8.479, Cited=414, 16873062].
Orans J, McSweeney EA, Iyer RR, ..., Beese LS (2011) Structures of human exonuclease 1 DNA complexes suggest a unified
mechanism for nuclease family. Cell. [IF=8.479, Cited=112, 21496642].
Vilenchik M, Solit D, Basso A, ..., Chiosis G (2004) Targeting wide-range oncogenic transformation via PU24FCl, a
specific inhibitor of tumor Hsp90. None. [IF=None, Cited=75, 15217612].
Lu AL, Clark S, Modrich P (2005) Methyl-directed repair of DNA base-pair mismatches in vitro. 1983. DNA Repair.
[IF=0.925, Cited=0, 15533843].
Liu Y, Kadyrov FA, Modrich P (2011) PARP-1 enhances the mismatch-dependence of 5'-directed excision in human mismatch
repair in vitro. None. [IF=None, Cited=32, 21945626].
Dzantiev L, Constantin N, Genschel J, ..., Modrich P (2004) A defined human system that supports bidirectional mismatch-
provoked excision. Molecular Cell. [IF=2.773, Cited=165, 15225546].
Koshiji M, To KKW, Hammer S, ..., Huang LE (2005) HIF-1alpha induces genetic instability by transcriptionally
downregulating MutSalpha expression. Molecular Cell. [IF=2.773, Cited=224, 15780936].
Warren JJ, Pohlhaus TJ, Changela A, ..., Beese LS (2007) Structure of the human MutSalpha DNA lesion recognition
complex. Molecular Cell. [IF=2.773, Cited=246, 17531815].
Sacho EJ, Kadyrov FA, Modrich P, ..., Erie DA (2008) Direct visualization of asymmetric adenine-nucleotide-induced
conformational changes in MutL alpha. Molecular Cell. [IF=2.773, Cited=86, 18206974].
Pillon MC, Lorenowicz JJ, Uckelmann M, ..., Guarné A (2010) Structure of the endonuclease domain of MutL: unlicensed to
cut. Molecular Cell. [IF=2.773, Cited=89, 20603082].
Rubin RA, Modrich P (1980) Purification and properties of EcoRI endonuclease. None. [IF=None, Cited=7, 6246382].
Hoyt PR, Doktycz MJ, Modrich P, ..., Allison DP (2000) Identifying sequence similarities between DNA molecules.
Ultramicroscopy. [IF=0.871, Cited=2, 10741675].
Iaccarino I, Palombo F, Drummond J, ..., Jiricny J (1996) MSH6, a Saccharomyces cerevisiae protein that binds to
mismatches as a heterodimer with MSH2. Current Biology. [IF=1.81, Cited=54, 8723353].
Genschel J, Modrich P (2003) Mechanism of 5'-directed excision in human mismatch repair. Molecular Cell. [IF=2.773,
Cited=169, 14636568].
Modrich P (1979) Structures and mechanisms of DNA restriction and modification enzymes. Quarterly Reviews of Biophysics.
[IF=1.372, Cited=55, 232555].
Brody RS, Adler S, Modrich P, ..., Frey PA (1982) Stereochemical course of nucleotidyl transfer catalyzed by
bacteriophage T7 induced DNA polymerase. Biochemistry. [IF=0.753, Cited=8, 7093204].
Nelson SF, McCusker JH, Sander MA, ..., Brown PO (1993) Genomic mismatch scanning: a new approach to genetic linkage
mapping. Nature Genetics. [IF=6.89, Cited=70, 8513319].
Bio FAB Group N, Baker D, Church G, ..., Weiss R (2006) Engineering life: building a fab for biology. None. [IF=None,
Cited=33, 16711359].
Eshleman JR, Donover PS, Littman SJ, ..., Veigl ML (1998) Increased transversions in a novel mutator colon cancer cell
line. Oncogene. [IF=1.523, Cited=8, 9528854].
Ma AH, Xia L, Littman SJ, ..., Sedwick WD (2000) Somatic mutation of hPMS2 as a possible cause of sporadic human colon
cancer with microsatellite instability. Oncogene. [IF=1.523, Cited=14, 10822375].
Yang Q, Zhang R, Wang XW, ..., Harris CC (2004) The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase.
Oncogene. [IF=1.523, Cited=43, 15064730].
Jack WE, Terry BJ, Modrich P (1982) Involvement of outside DNA sequences in the major kinetic path by which EcoRI
endonuclease locates and leaves its recognition sequence. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=85, 6287460].
Lu AL, Clark S, Modrich P (1983) Methyl-directed repair of DNA base-pair mismatches in vitro. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=173, 6308634].
Su SS, Modrich P (1986) Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=206, 3014530].
Lahue RS, Su SS, Modrich P (1987) Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=63, 3550791].
Drummond JT, Anthoney A, Brown R, Modrich P (1996) Cisplatin and adriamycin resistance are associated with MutLalpha and
mismatch repair deficiency in an ovarian tumor cell line. Journal of Biological Chemistry. [IF=1.122, Cited=173, 8702663].
Longley MJ, Pierce AJ, Modrich P (1997) DNA polymerase delta is required for human mismatch repair in vitro. Journal of
Biological Chemistry. [IF=1.122, Cited=110, 9099749].
Yamaguchi M, Dao V, Modrich P (1998) MutS and MutL activate DNA helicase II in a mismatch-dependent manner. Journal of
Biological Chemistry. [IF=1.122, Cited=96, 9535910].
Dao V, Modrich P (1998) Mismatch-, MutS-, MutL-, and helicase II-dependent unwinding from the single-strand break of an
incised heteroduplex. Journal of Biological Chemistry. [IF=1.122, Cited=81, 9535911].
Genschel J, Littman SJ, Drummond JT, Modrich P (1998) Isolation of MutSbeta from human cells and comparison of the
mismatch repair specificities of MutSbeta and MutSalpha. Journal of Biological Chemistry. [IF=1.122, Cited=252, 9677427].
Blackwell LJ, Bjornson KP, Modrich P (1998) DNA-dependent activation of the hMutSalpha ATPase. Journal of Biological
Chemistry. [IF=1.122, Cited=43, 9822679].
Blackwell LJ, Martik D, Bjornson KP, ..., Modrich P (1998) Nucleotide-promoted release of hMutSalpha from heteroduplex
DNA is consistent with an ATP-dependent translocation mechanism. Journal of Biological Chemistry. [IF=1.122, Cited=115, 9822680].
Littman SJ, Fang WH, Modrich P (1999) Repair of large insertion/deletion heterologies in human nuclear extracts is
directed by a 5' single-strand break and is independent of the mismatch repair system. Journal of Biological Chemistry.
[IF=1.122, Cited=23, 10066813].
Wright DJ, Jack WE, Modrich P (1999) The kinetic mechanism of EcoRI endonuclease. Journal of Biological Chemistry.
[IF=1.122, Cited=40, 10542216].
Spampinato C, Modrich P (2000) The MutL ATPase is required for mismatch repair. Journal of Biological Chemistry.
[IF=1.122, Cited=78, 10734142].
Blackwell LJ, Bjornson KP, Allen DJ, Modrich P (2001) Distinct MutS DNA-binding modes that are differentially modulated
by ATP binding and hydrolysis. Journal of Biological Chemistry. [IF=1.122, Cited=61, 11454861].
Blackwell LJ, Wang S, Modrich P (2001) DNA chain length dependence of formation and dynamics of
hMutSalpha.hMutLalpha.heteroduplex complexes. Journal of Biological Chemistry. [IF=1.122, Cited=69, 11441019].
Viswanathan M, Burdett V, Baitinger C, ..., Lovett ST (2001) Redundant exonuclease involvement in Escherichia coli
methyl-directed mismatch repair. Journal of Biological Chemistry. [IF=1.122, Cited=90, 11418610].
Genschel J, Modrich P (2009) Functions of MutLalpha, replication protein A (RPA), and HMGB1 in 5'-directed mismatch
repair. Journal of Biological Chemistry. [IF=1.122, Cited=34, 19515846].
Pluciennik A, Burdett V, Lukianova O, ..., Modrich P (2009) Involvement of the beta clamp in methyl-directed mismatch
repair in vitro. Journal of Biological Chemistry. [IF=1.122, Cited=33, 19783657].
Liu Y, Fang Y, Shao H, ..., Modrich P (2009) Interactions of human mismatch repair proteins MutSalpha and MutLalpha with
proteins of the ATR-Chk1 pathway. Journal of Biological Chemistry. [IF=1.122, Cited=44, 20029092].
Iyer RR, Pluciennik A, Genschel J, ..., Modrich P (2010) MutLalpha and proliferating cell nuclear antigen share binding
sites on MutSbeta. Journal of Biological Chemistry. [IF=1.122, Cited=38, 20154325].
Genschel J, Bazemore LR, Modrich P (2002) Human exonuclease I is required for 5' and 3' mismatch repair. Journal of
Biological Chemistry. [IF=1.122, Cited=149, 11809771].
Lindsey-Boltz LA, Kemp MG, Reardon JT, ..., Sancar A (2014) Coupling of human DNA excision repair and the DNA damage
checkpoint in a defined in vitro system. Journal of Biological Chemistry. [IF=1.122, Cited=41, 24403078].
Bjornson KP, Modrich P (2003) Differential and simultaneous adenosine di- and triphosphate binding by MutS. Journal of
Biological Chemistry. [IF=1.122, Cited=39, 12624105].
Bjornson KP, Blackwell LJ, Sage H, ..., Modrich P (2003) Assembly and molecular activities of the MutS tetramer. Journal
of Biological Chemistry. [IF=1.122, Cited=45, 12829697].
Baitinger C, Burdett V, Modrich P (2003) Hydrolytically deficient MutS E694A is defective in the MutL-dependent
activation of MutH and in the mismatch-dependent assembly of the MutS.MutL.heteroduplex complex. Journal of Biological
Chemistry. [IF=1.122, Cited=15, 14506224].
Martik D, Baitinger C, Modrich P (2004) Differential specificities and simultaneous occupancy of human MutSalpha
nucleotide binding sites. Journal of Biological Chemistry. [IF=1.122, Cited=38, 15105434].
Constantin N, Dzantiev L, Kadyrov FA, Modrich P (2005) Human mismatch repair: reconstitution of a nick-directed
bidirectional reaction. Journal of Biological Chemistry. [IF=1.122, Cited=157, 16188885].
López de Saro FJ, Marinus MG, Modrich P, O'Donnell M (2006) The beta sliding clamp binds to multiple sites within MutL
and MutS. Journal of Biological Chemistry. [IF=1.122, Cited=58, 16546997].
York SJ, Modrich P (2006) Mismatch repair-dependent iterative excision at irreparable O6-methylguanine lesions in human
nuclear extracts. Journal of Biological Chemistry. [IF=1.122, Cited=60, 16772289].
Kadyrov FA, Holmes SF, Arana ME, ..., Modrich P (2007) Saccharomyces cerevisiae MutLalpha is a mismatch repair
endonuclease. Journal of Biological Chemistry. [IF=1.122, Cited=168, 17951253].
Iyer RR, Pohlhaus TJ, Chen S, ..., Modrich P (2008) The MutSalpha-proliferating cell nuclear antigen interaction in
human DNA mismatch repair. Journal of Biological Chemistry. [IF=1.122, Cited=33, 18326858].
Allen DJ, Makhov A, Grilley M, ..., Griffith JD (1997) MutS mediates heteroduplex loop formation by a translocation
mechanism. EMBO Journal. [IF=2.114, Cited=177, 9250691].
Kim R, Modrich P, Kim SH (1984) 'Interactive' recognition in EcoRI restriction enzyme-DNA complex. Nucleic Acids
Research. [IF=4.663, Cited=14, 6093038].
Jiricny J, Su SS, Wood SG, Modrich P (1988) Mismatch-containing oligonucleotide duplexes bound by the E. coli mutS-
encoded protein. Nucleic Acids Research. [IF=4.663, Cited=50, 3047673].
Rubin RA, Modrich P (1978) Substrate dependence of the mechanism of EcoRI endonuclease. Nucleic Acids Research.
[IF=4.663, Cited=27, 211492].
Zhao J, Jain A, Iyer RR, ..., Vasquez KM (2009) Mismatch repair and nucleotide excision repair proteins cooperate in the
recognition of DNA interstrand crosslinks. Nucleic Acids Research. [IF=4.663, Cited=56, 19468048].
Nimonkar AV, Genschel J, Kinoshita E, ..., Kowalczykowski SC (2011) BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two
DNA end resection machineries for human DNA break repair. Genes and Development. [IF=1.985, Cited=465, 21325134].
Lu AL, Welsh K, Clark S, ..., Modrich P (1984) Repair of DNA base-pair mismatches in extracts of Escherichia coli. Cold
Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=56, 6397313].
Fang WH, Li GM, Longley M, ..., Modrich P (1993) Mismatch repair and genetic stability in human cells. Cold Spring
Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=9, 7956074].
Tseng Q, Orans J, Hast MA, ..., Beese LS (2011) Purification, crystallization and preliminary X-ray diffraction analysis
of the human mismatch repair protein MutSβ. None. [IF=None, Cited=3, 21821902].
Parsons R, Li GM, Longley M, ..., Vogelstein B (1995) Mismatch repair deficiency in phenotypically normal human cells.
Science. [IF=7.729, Cited=182, 7632227].
Herman GE, Modrich P (1981) Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. Journal of
Bacteriology. [IF=0.898, Cited=73, 7007328].
Cheng SC, Modrich P (1983) Positive-selection cloning vehicle useful for overproduction of hybrid proteins. Journal of
Bacteriology. [IF=0.898, Cited=35, 6302074].
Su SS, Grilley M, Thresher R, ..., Modrich P (1989) Gap formation is associated with methyl-directed mismatch correction
under conditions of restricted DNA synthesis. Genome. [IF=0.841, Cited=17, 2687086].
Modrich P (1987) DNA mismatch correction. Annual Review of Biochemistry. [IF=5.273, Cited=243, 3304141].
Friedman HS, McLendon RE, Kerby T, ..., Modrich P (1998) DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase
analysis and response to Temodal in newly diagnosed malignant glioma. Journal of Clinical Oncology. [IF=6.449,
Cited=231, 9850030].
Modrich P (1982) Studies on sequence recognition by type II restriction and modification enzymes. None. [IF=None,
Cited=40, 6293768].
Modrich P, Richardson CC (1975) Bacteriophage T7 Deoxyribonucleic acid replication in vitro. A protein of Escherichia
coli required for bacteriophage T7 DNA polymerase activity. Journal of Biological Chemistry. [IF=1.122, Cited=43, 1095578].
Modrich P, Richardson CC (1975) Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA
polymerase: an an emzyme composed of phage- and host-specific subunits. Journal of Biological Chemistry. [IF=1.122,
Cited=43, 1095579].
Bacolod MD, Johnson SP, Ali-Osman F, ..., Friedman HS (2002) Mechanisms of resistance to
1,3-bis(2-chloroethyl)-1-nitrosourea in human medulloblastoma and rhabdomyosarcoma. Molecular Cancer Therapeutics.
[IF=1.04, Cited=18, 12479369].
Bacolod MD, Johnson SP, Pegg AE, ..., Friedman HS (2004) Brain tumor cell lines resistant to
O6-benzylguanine/1,3-bis(2-chloroethyl)-1-nitrosourea chemotherapy have O6-alkylguanine-DNA alkyltransferase mutations.
Molecular Cancer Therapeutics. [IF=1.04, Cited=14, 15367707].
Au KG, Welsh K, Modrich P (1992) Initiation of methyl-directed mismatch repair. Journal of Biological Chemistry.
[IF=1.122, Cited=170, 1601880].
Panasenko SM, Modrich P, Lehman IR (1976) Modification of Escherichia coli DNA ligase by cleavage with trypsin. Journal
of Biological Chemistry. [IF=1.122, Cited=6, 179997].
Grilley M, Welsh KM, Su SS, Modrich P (1989) Isolation and characterization of the Escherichia coli mutL gene product.
Journal of Biological Chemistry. [IF=1.122, Cited=159, 2536011].
King K, Benkovic SJ, Modrich P (1989) Glu-111 is required for activation of the DNA cleavage center of EcoRI
endonuclease. Journal of Biological Chemistry. [IF=1.122, Cited=50, 2745417].
Wright DJ, King K, Modrich P (1989) The negative charge of Glu-111 is required to activate the cleavage center of EcoRI
endonuclease. Journal of Biological Chemistry. [IF=1.122, Cited=71, 2745418].
Welsh KM, Lu AL, Clark S, Modrich P (1987) Isolation and characterization of the Escherichia coli mutH gene product.
Journal of Biological Chemistry. [IF=1.122, Cited=125, 2824465].
Su SS, Lahue RS, Au KG, Modrich P (1988) Mispair specificity of methyl-directed DNA mismatch correction in vitro.
Journal of Biological Chemistry. [IF=1.122, Cited=183, 2834393].
Bowden DW, Modrich P (1985) In vitro maturation of circular bacteriophage P2 DNA. Purification of ter components and
characterization of the reaction. Journal of Biological Chemistry. [IF=1.122, Cited=27, 2987239].
Terry BJ, Jack WE, Modrich P (1985) Facilitated diffusion during catalysis by EcoRI endonuclease. Nonspecific
interactions in EcoRI catalysis. Journal of Biological Chemistry. [IF=1.122, Cited=81, 2997157].
Rubin RA, Modrich P (1977) EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme. Journal of
Biological Chemistry. [IF=1.122, Cited=99, 332688].
Modrich P, Rubin RA (1977) Role of the 2-amino group of deoxyguanosine in sequence recognition by EcoRI restriction and
modification enzymes. Journal of Biological Chemistry. [IF=1.122, Cited=29, 332689].
Terry BJ, Jack WE, Modrich P (1987) Mechanism of specific site location and DNA cleavage by EcoR I endonuclease. None.
[IF=None, Cited=12, 3333364].
Geier GE, Modrich P (1979) Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn
I endonuclease. Journal of Biological Chemistry. [IF=1.122, Cited=208, 368070].
Adler S, Modrich P (1979) T7-induced DNA polymerase. Characterization of associated exonuclease activities and
resolution into biologically active subunits. Journal of Biological Chemistry. [IF=1.122, Cited=13, 387776].
Cheng SC, Herman G, Modrich P (1985) Extent of equilibrium perturbation of the DNA helix upon enzymatic methylation of
adenine residues. Journal of Biological Chemistry. [IF=1.122, Cited=15, 3880739].
Modrich P, Anraku Y, Lehman IR (1973) Deoxyribonucleic acid ligase. Isolation and physical characterization of the
homogeneous enzyme from Escherichia coli. Journal of Biological Chemistry. [IF=1.122, Cited=56, 4355584].
Modrich P, Lehman IR, Wang JC (1972) Enzymatic joining of polynucleotides. XI. Reversal of Escherichia coli
deoxyribonucleic acid ligase reaction. Journal of Biological Chemistry. [IF=1.122, Cited=18, 4568616].
Modrich P, Lehman IR (1970) Enzymatic joining of polynucleotides. IX. A simple and rapid assay of polynucleotide joining
(ligase) activity by measurement of circle formation from linear deoxyadenylate-deoxythymidylate copolymer. Journal of
Biological Chemistry. [IF=1.122, Cited=84, 4919213].
Cheng SC, Kim R, King K, ..., Modrich P (1984) Isolation of gram quantities of EcoRI restriction and modification
enzymes from an overproducing strain. Journal of Biological Chemistry. [IF=1.122, Cited=34, 6088551].
Manavalan P, Johnson WC, Modrich P (1984) Prediction of secondary structure for Eco RI endonuclease. Journal of
Biological Chemistry. [IF=1.122, Cited=5, 6090442].
Bowden DW, Modrich P (1981) In vitro studies on the bacteriophage P2 terminase system. None. [IF=None, Cited=5, 6120523].
Lightner VA, Larson TJ, Tailleur P, ..., Modrich P (1980) Membrane phospholipid synthesis in Escherichia coli. Cloning
of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase. Journal of Biological Chemistry. [IF=1.122,
Cited=37, 6251087].
Newman AK, Rubin RA, Kim SH, Modrich P (1981) DNA sequences of structural genes for Eco RI DNA restriction and
modification enzymes. Journal of Biological Chemistry. [IF=1.122, Cited=96, 6257701].
Rubin RA, Modrich P, Vanaman TC (1981) Partial NH2- and cooh-terminal sequence analyses of Eco RI DNA restriction and
modification enzymes. Journal of Biological Chemistry. [IF=1.122, Cited=1, 6257702].
Lu AL, Jack WE, Modrich P (1981) DNA determinants important in sequence recognition by Eco RI endonuclease. Journal of
Biological Chemistry. [IF=1.122, Cited=50, 6273420].
Terry BJ, Jack WE, Rubin RA, Modrich P (1983) Thermodynamic parameters governing interaction of EcoRI endonuclease with
specific and nonspecific DNA sequences. Journal of Biological Chemistry. [IF=1.122, Cited=64, 6309785].
Lightner VA, Bell RM, Modrich P (1983) The DNA sequences encoding plsB and dgk loci of Escherichia coli. Journal of
Biological Chemistry. [IF=1.122, Cited=52, 6309817].
Adler S, Modrich P (1983) T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. Journal of
Biological Chemistry. [IF=1.122, Cited=29, 6343383].
Green PR, Vanaman TC, Modrich P, Bell RM (1983) Partial NH2- and COOH-terminal sequence and cyanogen bromide peptide
analysis of Escherichia coli sn-glycerol-3-phosphate acyltransferase. Journal of Biological Chemistry. [IF=1.122,
Cited=4, 6350296].
Jack WE, Rubin RA, Newman A, Modrich P (1981) Structures and mechanisms of Eco RI DNA restriction and modification
enzymes. None. [IF=None, Cited=3, 6765638].
Clark D, Lightner V, Edgar R, ..., Bell RM (1980) Regulation of phospholipid biosynthesis in Escherichia coli. Cloning
of the structural gene for the biosynthetic sn-glycerol-3-phosphate dehydrogenase. Journal of Biological Chemistry.
[IF=1.122, Cited=14, 6985897].
Larson TJ, Lightner VA, Green PR, ..., Bell RM (1980) Membrane phospholipid synthesis in Escherichia coli.
Identification of the sn-glycerol-3-phosphate acyltransferase polypeptide as the plsB gene product. Journal of
Biological Chemistry. [IF=1.122, Cited=24, 6997313].
Herman GE, Modrich P (1982) Escherichia coli dam methylase. Physical and catalytic properties of the homogeneous enzyme.
Journal of Biological Chemistry. [IF=1.122, Cited=76, 7037767].
Zinnen S, Hsieh JC, Modrich P (1994) Misincorporation and mispaired primer extension by human immunodeficiency virus
reverse transcriptase. Journal of Biological Chemistry. [IF=1.122, Cited=35, 7523369].
Hsieh JC, Zinnen S, Modrich P (1993) Kinetic mechanism of the DNA-dependent DNA polymerase activity of human
immunodeficiency virus reverse transcriptase. Journal of Biological Chemistry. [IF=1.122, Cited=90, 7693703].
Modrich P, Zabel D (1976) EcoRI endonuclease. Physical and catalytic properties of the homogenous enzyme. Journal of
Biological Chemistry. [IF=1.122, Cited=123, 786985].
Naegeli H, Modrich P, Friedberg EC (1993) The DNA helicase activities of Rad3 protein of Saccharomyces cerevisiae and
helicase II of Escherichia coli are differentially inhibited by covalent and noncovalent DNA modifications. Journal of
Biological Chemistry. [IF=1.122, Cited=24, 8387518].
Cooper DL, Lahue RS, Modrich P (1993) Methyl-directed mismatch repair is bidirectional. Journal of Biological Chemistry.
[IF=1.122, Cited=113, 8389365].
Grilley M, Griffith J, Modrich P (1993) Bidirectional excision in methyl-directed mismatch repair. Journal of Biological
Chemistry. [IF=1.122, Cited=76, 8505311].
Fang WH, Modrich P (1993) Human strand-specific mismatch repair occurs by a bidirectional mechanism similar to that of
the bacterial reaction. Journal of Biological Chemistry. [IF=1.122, Cited=123, 8505312].
Eshleman JR, Markowitz SD, Donover PS, ..., Sedwick WD (1996) Diverse hypermutability of multiple expressed sequence
motifs present in a cancer with microsatellite instability. Oncogene. [IF=1.523, Cited=26, 8622858].
Friedman HS, Johnson SP, Dong Q, ..., Modrich P (1997) Methylator resistance mediated by mismatch repair deficiency in a
glioblastoma multiforme xenograft. Cancer Research. [IF=1.624, Cited=64, 9230204].
Lee SE, Johnson SP, Hale LP, ..., Friedman HS (1998) Analysis of DNA mismatch repair proteins in human medulloblastoma.
Clinical Cancer Research. [IF=2.156, Cited=8, 9626457].

Modrich, Paul

Publication with MATCHING institution:

Publication with MISMATCHING institution:

Publication with MISSING institution: