MacKinnon, Roderick

Publication with MATCHING institution:

MacKinnon R (2004) Potassium channels and the atomic basis of selective ion conduction (Nobel Lecture). Angewandte
Chemie - International Edition. [IF=2.456, Cited=115, 15368373].
MacKinnon R (2004) Nobel Lecture. Potassium channels and the atomic basis of selective ion conduction. Bioscience
Reports. [IF=0.84, Cited=34, 15628664].
Lee CH, MacKinnon R (2017) Structures of the Human HCN1 Hyperpolarization-Activated Channel. Cell. [IF=8.479,
Cited=218, 28086084].
Hite RK, MacKinnon R (2017) Structural Titration of Slo2.2, a Na⁺-Dependent K⁺ Channel. Cell.
[IF=8.479, Cited=74, 28111072].
Wang W, MacKinnon R (2017) Cryo-EM Structure of the Open Human Ether-à-go-go-Related K⁺ Channel hERG. Cell.
[IF=8.479, Cited=270, 28431243].
Sun J, MacKinnon R (2017) Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.
Cell. [IF=8.479, Cited=185, 28575668].
Lee CH, MacKinnon R (2019) Voltage Sensor Movements during Hyperpolarization in the HCN Channel. Cell. [IF=8.479,
Cited=64, 31787376].
Sun J, MacKinnon R (2019) Structural Basis of Human KCNQ1 Modulation and Gating. Cell. [IF=8.479, Cited=125, 31883792].
Zhao C, MacKinnon R (2022) Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron. [IF=3.346,
Cited=12, 36283409].
MacKinnon R (2003) Potassium channels. FEBS Letters. [IF=0.871, Cited=233, 14630320].
Valiyaveetil FI, Zhou Y, MacKinnon R (2002) Lipids in the structure, folding, and function of the KcsA K+ channel.
Biochemistry. [IF=0.753, Cited=193, 12196015].
Ruta V, MacKinnon R (2004) Localization of the voltage-sensor toxin receptor on KvAP. Biochemistry. [IF=0.753,
Cited=51, 15287735].
Zhou Y, MacKinnon R (2004) Ion binding affinity in the cavity of the KcsA potassium channel. Biochemistry. [IF=0.753,
Cited=55, 15109256].
Imredy JP, Chen C, MacKinnon R (1998) A snake toxin inhibitor of inward rectifier potassium channel ROMK1. Biochemistry.
[IF=0.753, Cited=37, 9778362].
Valiyaveetil FI, MacKinnon R, Muir TW (2002) Semisynthesis and folding of the potassium channel KcsA. Journal of the
American Chemical Society. [IF=2.573, Cited=91, 12149015].
Valiyaveetil FI, Sekedat M, MacKinnon R, Muir TW (2006) Structural and functional consequences of an amide-to-ester
substitution in the selectivity filter of a potassium channel. Journal of the American Chemical Society. [IF=2.573,
Cited=32, 16939283].
Endeward B, Butterwick JA, MacKinnon R, Prisner TF (2009) Pulsed electron-electron double-resonance determination of
spin-label distances and orientations on the tetrameric potassium ion channel KcsA. Journal of the American Chemical
Society. [IF=2.573, Cited=53, 19919160].
Brohawn SG, Campbell EB, MacKinnon R (2014) Physical mechanism for gating and mechanosensitivity of the human TRAAK K+
channel. Nature. [IF=11.591, Cited=165, 25471887].
Hite RK, Yuan P, Li Z, ..., MacKinnon R (2015) Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+)
channel. Nature. [IF=11.591, Cited=75, 26436452].
Tao X, Hite RK, MacKinnon R (2016) Cryo-EM structure of the open high-conductance Ca²⁺-activated
K⁺ channel. Nature. [IF=11.591, Cited=136, 27974795].
Hite RK, Tao X, MacKinnon R (2016) Structural basis for gating the high-conductance Ca²⁺-activated
K⁺ channel. Nature. [IF=11.591, Cited=107, 27974801].
Park E, Campbell EB, MacKinnon R (2016) Structure of a CLC chloride ion channel by cryo-electron microscopy. Nature.
[IF=11.591, Cited=72, 28002411].
Lin YC, Guo YR, Miyagi A, ..., Scheuring S (2019) Force-induced conformational changes in PIEZO1. Nature. [IF=11.591,
Cited=126, 31435018].
Lee SY, Lee A, Chen J, MacKinnon R (2005) Structure of the KvAP voltage-dependent K+ channel and its dependence on the
lipid membrane. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=191, 16223877].
Schmidt D, MacKinnon R (2008) Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the
mechanical state of the lipid membrane. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=96, 19050073].
Schmidt D, del Mármol J, MacKinnon R (2012) Mechanistic basis for low threshold mechanosensitivity in voltage-dependent
K+ channels. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=55, 22675122].
Feng L, Campbell EB, MacKinnon R (2012) Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=56, 22753511].
Brohawn SG, Campbell EB, MacKinnon R (2013) Domain-swapped chain connectivity and gated membrane access in a Fab-
mediated crystal of the human TRAAK K+ channel. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=78, 23341632].
Brohawn SG, Su Z, MacKinnon R (2014) Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K+
channels. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=192, 24550493].
Su Z, Brown EC, Wang W, MacKinnon R (2016) Novel cell-free high-throughput screening method for pharmacological tools
targeting K+ channels. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=58, 27091997].
Zhao C, MacKinnon R (2021) Molecular structure of an open human K_ATP channel. Proceedings of the National
Academy of Sciences of the United States of America. [IF=2.765, Cited=29, 34815345].
Zhang Y, Tao X, MacKinnon R (2022) Correlation between structure and function in phosphatidylinositol lipid-dependent
Kir2.2 gating. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=2, 35286194].
Haselwandter CA, Guo YR, Fu Z, MacKinnon R (2022) Quantitative prediction and measurement of Piezo's membrane footprint.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=11, 36166475].
Haselwandter CA, Guo YR, Fu Z, MacKinnon R (2022) Elastic properties and shape of the Piezo dome underlying its
mechanosensory function. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=10, 36166476].
Mandala VS, MacKinnon R (2022) Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=19, 36331999].
Pérez-Mitta G, MacKinnon R (2023) Freestanding lipid bilayer tensiometer for the study of mechanosensitive ion channels.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=2, 36913590].
Falzone ME, MacKinnon R (2023) Gβγ activates PIP2 hydrolysis by recruiting and orienting PLCβ on
the membrane surface. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=2, 37172014].
Mandala VS, MacKinnon R (2023) The membrane electric field regulates the PIP₂-binding site to gate the KCNQ1
channel. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=5, 37192161].
Tao X, Zhao C, MacKinnon R (2023) Membrane protein isolation and structure determination in cell-derived membrane
vesicles. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=11, 37098056].
Falzone ME, MacKinnon R (2023) The mechanism of Gα_q regulation of PLCβ3-catalyzed PIP2
hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=0, 37991948].
Fu Z, MacKinnon R (2024) Structure of the flotillin complex in a native membrane environment. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=1, 38985763].
Morrill JA, MacKinnon R (1999) Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic
nucleotide-gated channel. Journal of General Physiology. [IF=0.994, Cited=30, 10398693].
Jiang Y, MacKinnon R (2000) The barium site in a potassium channel by x-ray crystallography. Journal of General
Physiology. [IF=0.994, Cited=126, 10694255].
Pérez-Mitta G, Sezgin Y, Wang W, MacKinnon R (2024) Freestanding bilayer microscope for single-molecule imaging of
membrane proteins. Science advances. [IF=2.861, Cited=0, 38905330].
Dutzler R, Campbell EB, MacKinnon R (2003) Gating the selectivity filter in ClC chloride channels. Science. [IF=7.729,
Cited=464, 12649487].
Tao X, Avalos JL, Chen J, MacKinnon R (2009) Crystal structure of the eukaryotic strong inward-rectifier K+ channel
Kir2.2 at 3.1 A resolution. Science. [IF=7.729, Cited=226, 20019282].
Tao X, Lee A, Limapichat W, ..., MacKinnon R (2010) A gating charge transfer center in voltage sensors. Science.
[IF=7.729, Cited=347, 20360102].
Yuan P, Leonetti MD, Pico AR, ..., MacKinnon R (2010) Structure of the human BK channel Ca2+-activation apparatus at 3.0
A resolution. Science. [IF=7.729, Cited=192, 20508092].
Feng L, Campbell EB, Hsiung Y, MacKinnon R (2010) Structure of a eukaryotic CLC transporter defines an intermediate
state in the transport cycle. Science. [IF=7.729, Cited=186, 20929736].
Brohawn SG, del Mármol J, MacKinnon R (2012) Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+
ion channel. Science. [IF=7.729, Cited=256, 22282805].
MacKinnon R, Cohen SL, Kuo A, ..., Chait BT (1998) Structural conservation in prokaryotic and eukaryotic potassium
channels. Science. [IF=7.729, Cited=212, 9525854].
Doyle DA, Morais Cabral J, Pfuetzner RA, ..., MacKinnon R (1998) The structure of the potassium channel: molecular basis
of K+ conduction and selectivity. Science. [IF=7.729, Cited=1000, 9525859].
Roux B, MacKinnon R (1999) The cavity and pore helices in the KcsA K+ channel: electrostatic stabilization of monovalent
cations. Science. [IF=7.729, Cited=218, 10390357].
Gulbis JM, Zhou M, Mann S, MacKinnon R (2000) Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent
K+ channels. Science. [IF=7.729, Cited=207, 10884227].
Whicher JR, MacKinnon R (2016) Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing
mechanism. Science. [IF=7.729, Cited=198, 27516594].
Lee CH, MacKinnon R (2018) Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM
structures. Science. [IF=7.729, Cited=101, 29724949].
Wang W, Whorton MR, MacKinnon R (2014) Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the
signaling lipid PIP2 and Na+ in a reconstituted system. eLife. [IF=1.743, Cited=37, 25049222].
Hite RK, Butterwick JA, MacKinnon R (2014) Phosphatidic acid modulation of Kv channel voltage sensor function. eLife.
[IF=1.743, Cited=33, 25285449].
Touhara KK, Wang W, MacKinnon R (2016) The GIRK1 subunit potentiates G protein activation of cardiac GIRK1/4 hetero-
tetramers. eLife. [IF=1.743, Cited=10, 27074664].
Wang W, Touhara KK, Weir K, ..., MacKinnon R (2016) Cooperative regulation by G proteins and Na(+) of neuronal GIRK2
K(+) channels. eLife. [IF=1.743, Cited=25, 27074662].
Lee KPK, Chen J, MacKinnon R (2017) Molecular structure of human KATP in complex with ATP and ADP. eLife. [IF=1.743,
Cited=87, 29286281].
Del Mármol JI, Touhara KK, Croft G, MacKinnon R (2018) Piezo1 forms a slowly-inactivating mechanosensory channel in
mouse embryonic stem cells. eLife. [IF=1.743, Cited=34, 30132757].
Guo YR, MacKinnon R (2017) Structure-based membrane dome mechanism for Piezo mechanosensitivity. eLife. [IF=1.743,
Cited=164, 29231809].
Park E, MacKinnon R (2018) Structure of the CLC-1 chloride channel from Homo sapiens. eLife. [IF=1.743,
Cited=51, 29809153].
Haselwandter CA, MacKinnon R (2018) Piezo's membrane footprint and its contribution to mechanosensitivity. eLife.
[IF=1.743, Cited=60, 30480546].
Touhara KK, MacKinnon R (2018) Molecular basis of signaling specificity between GIRK channels and GPCRs. eLife.
[IF=1.743, Cited=25, 30526853].
Whicher JR, MacKinnon R (2019) Regulation of Eag1 gating by its intracellular domains. eLife. [IF=1.743, Cited=12, 31490124].
Brohawn SG, Wang W, Handler A, ..., MacKinnon R (2019) The mechanosensitive ion channel TRAAK is localized to the
mammalian node of Ranvier. eLife. [IF=1.743, Cited=46, 31674909].
Tao X, MacKinnon R (2019) Molecular structures of the human Slo1 K⁺ channel in complex with β4. eLife.
[IF=1.743, Cited=59, 31815672].
Tao X, MacKinnon R (2019) Cryo-EM structure of the KvAP channel reveals a non-domain-swapped voltage sensor topology.
eLife. [IF=1.743, Cited=11, 31755864].
Niu Y, Tao X, Touhara KK, MacKinnon R (2020) Cryo-EM analysis of PIP₂ regulation in mammalian GIRK channels.
eLife. [IF=1.743, Cited=39, 32844743].
Niu Y, Tao X, Vaisey G, ..., MacKinnon R (2021) Analysis of the mechanosensor channel functionality of TACAN. eLife.
[IF=1.743, Cited=12, 34374644].
Vaisey G, Banerjee P, North AJ, ..., MacKinnon R (2022) Piezo1 as a force-through-membrane sensor in red blood cells.
eLife. [IF=1.743, Cited=9, 36515266].

Publication with MISMATCHING institution:

MacKinnon PJ, Powell BC, Rogers GE, ..., Sutherland GR (1991) An ultrahigh-sulphur keratin gene of the human hair
cuticle is located at 11q13 and cross-hybridizes with sequences at 11p15. Mammalian Genome. [IF=0.583, Cited=9, 1724400].
MacKinnon R (1991) Using mutagenesis to study potassium channel mechanisms. Journal of Bioenergetics and Biomembranes.
[IF=0.676, Cited=10, 1917912].
MacKinnon R, Reinhart PH, White MM (1988) Charybdotoxin block of Shaker K+ channels suggests that different types of K+
channels share common structural features. Neuron. [IF=3.346, Cited=78, 2483094].
MacKinnon R, Heginbotham L, Abramson T (1990) Mapping the receptor site for charybdotoxin, a pore-blocking potassium
channel inhibitor. Neuron. [IF=3.346, Cited=125, 1702643].
MacKinnon R (1995) Pore loops: an emerging theme in ion channel structure. Neuron. [IF=3.346, Cited=141, 7538310].
MacKinnon R (1991) New insights into the structure and function of potassium channels. Current Opinion in Neurobiology.
[IF=1.341, Cited=22, 1822292].
McKearney RM, MacKinnon RC, MacKinnon R, ..., Baker R (2018) Tinnitus information online - does it ring true? Journal of
Laryngology and Otology. [IF=0.909, Cited=7, 30353795].
MacKinnon R, Miller C (1989) Functional modification of a Ca2+-activated K+ channel by trimethyloxonium. Biochemistry.
[IF=0.753, Cited=46, 2481495].
MacKinnon R, Latorre R, Miller C (1989) Role of surface electrostatics in the operation of a high-conductance
Ca2+-activated K+ channel. Biochemistry. [IF=0.753, Cited=95, 2605175].
Lu Z, MacKinnon R (1997) Purification, characterization, and synthesis of an inward-rectifier K+ channel inhibitor from
scorpion venom. Biochemistry. [IF=0.753, Cited=29, 9188688].
MacKinnon R (1991) Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature.
[IF=11.591, Cited=546, 1706481].
MacKinnon R, Wheeler KI, Sokol J (2011) Endotracheal DNase for atelectasis in ventilated neonates. Journal of
Perinatology. [IF=1.323, Cited=4, 22124516].
Lu Z, MacKinnon R (1994) A conductance maximum observed in an inward-rectifier potassium channel. Journal of General
Physiology. [IF=0.994, Cited=31, 7807057].
Anderson CS, MacKinnon R, Smith C, Miller C (1988) Charybdotoxin block of single Ca2+-activated K+ channels. Effects of
channel gating, voltage, and ionic strength. Journal of General Physiology. [IF=0.994, Cited=144, 2454282].
MacKinnon R, Miller C (1988) Mechanism of charybdotoxin block of the high-conductance, Ca2+-activated K+ channel.
Journal of General Physiology. [IF=0.994, Cited=203, 2454283].
Heginbotham L, Abramson T, MacKinnon R (1992) A functional connection between the pores of distantly related ion
channels as revealed by mutant K+ channels. Science. [IF=7.729, Cited=259, 1279807].
Yellen G, Jurman ME, Abramson T, MacKinnon R (1991) Mutations affecting internal TEA blockade identify the probable
pore-forming region of a K+ channel. Science. [IF=7.729, Cited=351, 2000494].
MacKinnon R, Yellen G (1990) Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels.
Science. [IF=7.729, Cited=322, 2218530].
MacKinnon R, Miller C (1989) Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide
inhibitor. Science. [IF=7.729, Cited=197, 2476850].
Root MJ, MacKinnon R (1994) Two identical noninteracting sites in an ion channel revealed by proton transfer. Science.
[IF=7.729, Cited=106, 7522344].
MacKinnon R, Aldrich RW, Lee AW (1993) Functional stoichiometry of Shaker potassium channel inactivation. Science.
[IF=7.729, Cited=111, 7694359].
Hidalgo P, MacKinnon R (1995) Revealing the architecture of a K+ channel pore through mutant cycles with a peptide
inhibitor. Science. [IF=7.729, Cited=288, 7716527].
MacKinnon R, Stoeter R, Doherty C, ..., Chang TP (2015) Self-motivated learning with gamification improves infant CPR
performance, a randomised controlled trial. BMJ Simulation and Technology Enhanced Learning. [IF=0.495, Cited=3, 35515202].
MacKinnon R, Gwathmey JK, Allen PD, ..., Morgan JP (1988) Modulation by the thyroid state of intracellular calcium and
contractility in ferret ventricular muscle. Circulation Research. [IF=3.534, Cited=27, 3197273].
Marshall RD, Vaughan SC, MacKinnon R, ..., Roose SP (1996) Assessing outcome in psychoanalysis and long-term dynamic
psychotherapy. None. [IF=None, Cited=1, 9220374].
MacKinnon R, Hirst MC, Bell MV, ..., Davies KE (1990) Microdissection of the fragile X region. American Journal of Human
Genetics. [IF=2.607, Cited=24, 2378345].

Publication with MISSING institution:

Hirst MC, Bell MV, MacKinnon R, ..., Ledbetter D (1991) Mapping of a cerebellar degeneration related protein and DXS304
around the fragile site. None. [IF=None, Cited=4, 1673311].
Valiyaveetil FI, Sekedat M, Muir TW, MacKinnon R (2004) Semisynthesis of a functional K+ channel. Angewandte Chemie -
International Edition. [IF=2.456, Cited=29, 15127436].
Krezel AM, Kasibhatla C, Hidalgo P, ..., Wagner G (1995) Solution structure of the potassium channel inhibitor agitoxin
2: caliper for probing channel geometry. Protein Science. [IF=1.97, Cited=71, 8520473].
Imredy JP, MacKinnon R (2000) Energetic and structural interactions between delta-dendrotoxin and a voltage-gated
potassium channel. Journal of Molecular Biology. [IF=1.281, Cited=42, 10698633].
Hyland VJ, Suthers GK, Friend K, ..., Sutherland GR (1990) Probe, VK5B, is located in the same interval as the autosomal
dominant adult polycystic kidney disease locus, PKD1. Human Genetics. [IF=1.653, Cited=18, 1968038].
Hyland VJ, Fernandez KE, Callen DF, ..., Sutherland GR (1989) Assignment of anonymous DNA probes to specific intervals
of human chromosomes 16 and X. Human Genetics. [IF=1.653, Cited=18, 2570019].
Blair HJ, Hirst MC, MacKinnon R, ..., Boyd Y (1994) Evaluation of human microdissection clones from the FRAXA region as
tools for comparative mapping in the mouse: isolation of a conserved genomic clone close to FMR1. Mammalian Genome.
[IF=0.583, Cited=2, 8000145].
Moore SS, MacKinnon R, Hetzel DJ, Barendse W (1995) The cosmid CSSM25 assigns syntenic group U2 to bovine chromosome 9
and is localized to ovine chromosome 8. Mammalian Genome. [IF=0.583, Cited=3, 8589522].
MacKinnon R, Morgan JP (1986) Influence of the thyroid state on the calcium transient in ventricular muscle. Pflugers
Archiv European Journal of Physiology. [IF=1.211, Cited=16, 2428004].
MacKinnon R, Gwathmey JK, Morgan JP (1987) Differential effects of reoxygenation on intracellular calcium and isometric
tension. Pflugers Archiv European Journal of Physiology. [IF=1.211, Cited=20, 3627961].
Love J, Mancia F, Shapiro L, ..., Hendrickson WA (2010) The New York Consortium on Membrane Protein Structure (NYCOMPS):
a high-throughput platform for structural genomics of integral membrane proteins. None. [IF=None, Cited=34, 20690043].
Bell MV, Hirst MC, Nakahori Y, ..., Froster-Iskenius U (1991) Physical mapping across the fragile X: hypermethylation
and clinical expression of the fragile X syndrome. Cell. [IF=8.479, Cited=230, 1997211].
Hirst MC, Roche A, Flint TJ, ..., Boyd Y (1991) Linear order of new and established DNA markers around the fragile site
at Xq27.3. Genomics. [IF=1.012, Cited=20, 2045104].
Daniels RJ, Thomas NH, MacKinnon R, ..., Zerres K (1992) Linkage analysis of spinal muscular atrophy. Genomics.
[IF=1.012, Cited=23, 1346777].
Heginbotham L, MacKinnon R (1992) The aromatic binding site for tetraethylammonium ion on potassium channels. Neuron.
[IF=3.346, Cited=268, 1550673].
Root MJ, MacKinnon R (1993) Identification of an external divalent cation-binding site in the pore of a cGMP-activated
channel. Neuron. [IF=3.346, Cited=134, 7691102].
Perozo E, MacKinnon R, Bezanilla F, Stefani E (1993) Gating currents from a nonconducting mutant reveal open-closed
conformations in Shaker K+ channels. Neuron. [IF=3.346, Cited=232, 8352943].
Gross A, Abramson T, MacKinnon R (1994) Transfer of the scorpion toxin receptor to an insensitive potassium channel.
Neuron. [IF=3.346, Cited=52, 7946339].
Swartz KJ, MacKinnon R (1995) An inhibitor of the Kv2.1 potassium channel isolated from the venom of a Chilean
tarantula. Neuron. [IF=3.346, Cited=157, 7576642].
Schumaker MF, MacKinnon R (1990) A simple model for multi-ion permeation. Single-vacancy conduction in a simple pore
model. Biophysical Journal. [IF=0.842, Cited=34, 1701102].
Heginbotham L, MacKinnon R (1993) Conduction properties of the cloned Shaker K+ channel. Biophysical Journal. [IF=0.842,
Cited=114, 8298038].
Heginbotham L, Lu Z, Abramson T, MacKinnon R (1994) Mutations in the K+ channel signature sequence. Biophysical Journal.
[IF=0.842, Cited=452, 8038378].
Ruta V, Chen J, MacKinnon R (2005) Calibrated measurement of gating-charge arginine displacement in the KvAP voltage-
dependent K+ channel. Cell. [IF=8.479, Cited=154, 16269337].
Whorton MR, MacKinnon R (2011) Crystal structure of the mammalian GIRK2 K+ channel and gating regulation by G proteins,
PIP2, and sodium. Cell. [IF=8.479, Cited=295, 21962516].
Zhou Y, MacKinnon R (2003) The occupancy of ions in the K+ selectivity filter: charge balance and coupling of ion
binding to a protein conformational change underlie high conduction rates. Journal of Molecular Biology. [IF=1.281,
Cited=242, 14583193].
Zhou M, MacKinnon R (2004) A mutant KcsA K(+) channel with altered conduction properties and selectivity filter ion
distribution. Journal of Molecular Biology. [IF=1.281, Cited=79, 15099749].
Ohndorf UM, MacKinnon R (2005) Construction of a cyclic nucleotide-gated KcsA K+ channel. Journal of Molecular Biology.
[IF=1.281, Cited=13, 15979092].
Banerjee A, MacKinnon R (2008) Inferred motions of the S3a helix during voltage-dependent K+ channel gating. Journal of
Molecular Biology. [IF=1.281, Cited=21, 18632115].
Tao X, MacKinnon R (2008) Functional analysis of Kv1.2 and paddle chimera Kv channels in planar lipid bilayers. Journal
of Molecular Biology. [IF=1.281, Cited=36, 18638484].
Lee SY, Letts JA, MacKinnon R (2009) Functional reconstitution of purified human Hv1 H+ channels. Journal of Molecular
Biology. [IF=1.281, Cited=76, 19233200].
Schmidt D, Cross SR, MacKinnon R (2009) A gating model for the archeal voltage-dependent K(+) channel KvAP in DPhPC and
POPE:POPG decane lipid bilayers. Journal of Molecular Biology. [IF=1.281, Cited=48, 19481093].
Butterwick JA, MacKinnon R (2010) Solution structure and phospholipid interactions of the isolated voltage-sensor domain
from KvAP. Journal of Molecular Biology. [IF=1.281, Cited=57, 20851706].
Gulbis JM, Mann S, MacKinnon R (1999) Structure of a voltage-dependent K+ channel beta subunit. Cell. [IF=8.479,
Cited=173, 10399921].
Doyle DA, Lee A, Lewis J, ..., MacKinnon R (1996) Crystal structures of a complexed and peptide-free membrane protein-
binding domain: molecular basis of peptide recognition by PDZ. Cell. [IF=8.479, Cited=681, 8674113].
Yifrach O, MacKinnon R (2002) Energetics of pore opening in a voltage-gated K(+) channel. Cell. [IF=8.479, Cited=220, 12408867].
Nishida M, MacKinnon R (2002) Structural basis of inward rectification: cytoplasmic pore of the G protein-gated inward
rectifier GIRK1 at 1.8 A resolution. Cell. [IF=8.479, Cited=240, 12507423].
Ranganathan R, Lewis JH, MacKinnon R (1996) Spatial localization of the K+ channel selectivity filter by mutant cycle-
based structure analysis. Neuron. [IF=3.346, Cited=185, 8562077].
Gross A, MacKinnon R (1996) Agitoxin footprinting the shaker potassium channel pore. Neuron. [IF=3.346, Cited=100, 8789954].
Aggarwal SK, MacKinnon R (1996) Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron.
[IF=3.346, Cited=507, 8663993].
Swartz KJ, MacKinnon R (1997) Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding
sites. Neuron. [IF=3.346, Cited=171, 9136774].
Swartz KJ, MacKinnon R (1997) Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+
channels. Neuron. [IF=3.346, Cited=159, 9136775].
Jiang Y, Pico A, Cadene M, ..., MacKinnon R (2001) Structure of the RCK domain from the E. coli K+ channel and
demonstration of its presence in the human BK channel. Neuron. [IF=3.346, Cited=208, 11301020].
Lu Z, MacKinnon R (1995) Probing a potassium channel pore with an engineered protonatable site. Biochemistry. [IF=0.753,
Cited=15, 7548074].
Park CS, MacKinnon R (1995) Divalent cation selectivity in a cyclic nucleotide-gated ion channel. Biochemistry.
[IF=0.753, Cited=39, 7577917].
Escobar L, Root MJ, MacKinnon R (1993) Influence of protein surface charge on the bimolecular kinetics of a potassium
channel peptide inhibitor. Biochemistry. [IF=0.753, Cited=30, 7687466].
Garcia ML, Garcia-Calvo M, Hidalgo P, ..., MacKinnon R (1994) Purification and characterization of three inhibitors of
voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry. [IF=0.753, Cited=161, 8204618].
Hille B, Armstrong CM, MacKinnon R (1999) Ion channels: from idea to reality. Nature Medicine. [IF=11.877, Cited=65, 10502800].
Zhou M, Morais-Cabral JH, Mann S, MacKinnon R (2001) Potassium channel receptor site for the inactivation gate and
quaternary amine inhibitors. Nature. [IF=11.591, Cited=378, 11395760].
Morais-Cabral JH, Zhou Y, MacKinnon R (2001) Energetic optimization of ion conduction rate by the K+ selectivity filter.
Nature. [IF=11.591, Cited=425, 11689935].
Zhou Y, Morais-Cabral JH, Kaufman A, MacKinnon R (2001) Chemistry of ion coordination and hydration revealed by a K+
channel-Fab complex at 2.0 A resolution. Nature. [IF=11.591, Cited=1000, 11689936].
Lu Z, MacKinnon R (1994) Electrostatic tuning of Mg2+ affinity in an inward-rectifier K+ channel. Nature. [IF=11.591,
Cited=201, 7915826].
Dutzler R, Campbell EB, Cadene M, ..., MacKinnon R (2002) X-ray structure of a ClC chloride channel at 3.0 A reveals the
molecular basis of anion selectivity. Nature. [IF=11.591, Cited=928, 11796999].
MacKinnon R (2002) Nothing automatic about ion-channel structures. Nature. [IF=11.591, Cited=6, 11907549].
Jiang Y, Lee A, Chen J, ..., MacKinnon R (2002) Crystal structure and mechanism of a calcium-gated potassium channel.
Nature. [IF=11.591, Cited=841, 12037559].
Jiang Y, Lee A, Chen J, ..., MacKinnon R (2002) The open pore conformation of potassium channels. Nature. [IF=11.591,
Cited=763, 12037560].
Ruta V, Jiang Y, Lee A, ..., MacKinnon R (2003) Functional analysis of an archaebacterial voltage-dependent K+ channel.
Nature. [IF=11.591, Cited=142, 12629550].
Jiang Y, Lee A, Chen J, ..., MacKinnon R (2003) X-ray structure of a voltage-dependent K+ channel. Nature. [IF=11.591,
Cited=1000, 12721618].
Jiang Y, Ruta V, Chen J, ..., MacKinnon R (2003) The principle of gating charge movement in a voltage-dependent K+
channel. Nature. [IF=11.591, Cited=494, 12721619].
Lee SY, MacKinnon R (2004) A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider
venom. Nature. [IF=11.591, Cited=183, 15241419].
Jiang QX, Wang DN, MacKinnon R (2004) Electron microscopic analysis of KvAP voltage-dependent K+ channels in an open
conformation. Nature. [IF=11.591, Cited=81, 15306816].
Schmidt D, Jiang QX, MacKinnon R (2006) Phospholipids and the origin of cationic gating charges in voltage sensors.
Nature. [IF=11.591, Cited=250, 17136096].
Long SB, Tao X, Campbell EB, MacKinnon R (2007) Atomic structure of a voltage-dependent K+ channel in a lipid membrane-
like environment. Nature. [IF=11.591, Cited=985, 18004376].
Hansen SB, Tao X, MacKinnon R (2011) Structural basis of PIP2 activation of the classical inward rectifier K+ channel
Kir2.2. Nature. [IF=11.591, Cited=407, 21874019].
Yuan P, Leonetti MD, Hsiung Y, MacKinnon R (2011) Open structure of the Ca2+ gating ring in the high-conductance
Ca2+-activated K+ channel. Nature. [IF=11.591, Cited=92, 22139424].
Whorton MR, MacKinnon R (2013) X-ray structure of the mammalian GIRK2-βγ G-protein complex. Nature. [IF=11.591,
Cited=195, 23739333].
MacKinnon R, Doyle DA (1997) Prokaryotes offer hope for potassium channel structural studies. None. [IF=None, Cited=9, 9360597].
Nishida M, Cadene M, Chait BT, MacKinnon R (2007) Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO
Journal. [IF=2.114, Cited=202, 17703190].
MacKinnon R, Michels R (1970) The role of the teleohone in the psychiatric interview. Psychiatry (New York). [IF=0.95,
Cited=3, 5415514].
Hanison J, Jackson M, MacKinnon R (2011) Low-flow anaesthesia in paediatric patients. British Journal of Anaesthesia.
[IF=3.136, Cited=0, 21317238].
Hirst MC, Rack K, Nakahori Y, ..., Littler AJ (1991) A YAC contig across the fragile X site defines the region of
fragility. Nucleic Acids Research. [IF=4.663, Cited=29, 2062644].
Rosenthal A, MacKinnon R, Jones DS (1991) PCR walking from microdissection clone M54 identifies three exons from the
human gene for the neural cell adhesion molecule L1 (CAM-L1). Nucleic Acids Research. [IF=4.663, Cited=12, 1923824].
Hunt W, MacKinnon R, Michels R (1975) A clinical clerkship in psychiatry. None. [IF=None, Cited=6, 1195326].
Falzone ME, MacKinnon R (2023) The mechanism of Gα _q regulation of PLCβ3 -catalyzed PIP2
hydrolysis. None. [IF=None, Cited=0, 37693483].
Watts RW, Marley JE, Beilby JJ, ..., Doughty S (1997) Training, skills and approach to high-risk obstetrics in rural GP
obstetricians. Australian and New Zealand Journal of Obstetrics and Gynaecology. [IF=0.975, Cited=1, 9429705].
Byrne E, MacKinnon R (2006) Should premedication be used for semi-urgent or elective intubation in neonates? Archives of
Disease in Childhood. [IF=1.513, Cited=15, 16371384].
Gwathmey JK, Copelas L, MacKinnon R, ..., Morgan JP (1987) Abnormal intracellular calcium handling in myocardium from
patients with end-stage heart failure. Circulation Research. [IF=3.534, Cited=451, 3608112].
Kass F, MacKinnon R, Spitzer RL (1986) Masochistic personality: an empirical study. American Journal of Psychiatry.
[IF=3.582, Cited=4, 3946658].
Marshall R, Spitzer R, Vaughan S, ..., Roose S (2001) Assessing the subjective experience of being a participant in
psychiatric research. American Journal of Psychiatry. [IF=3.582, Cited=20, 11156821].
Lockless SW, Zhou M, MacKinnon R (2007) Structural and thermodynamic properties of selective ion binding in a K+
channel. PLoS Biology. [IF=2.285, Cited=130, 17472437].
Lee SY, Banerjee A, MacKinnon R (2009) Two separate interfaces between the voltage sensor and pore are required for the
function of voltage-dependent K(+) channels. PLoS Biology. [IF=2.285, Cited=105, 19260762].
Sutcliffe RG, Bolton AE, Sharp F, ..., MacKinnon R (1980) Purification of human alpha uterine protein. None. [IF=None,
Cited=11, 7431275].
MacKinnon R (1967) A British dental surgery assistant in N.Z. None. [IF=None, Cited=0, 5233175].
MacKinnon R, Talbott JA, Holloway B (1969) Psychiatric care through home nursing services. None. [IF=None, Cited=0, 5348928].
Piper TJ, MacKinnon R (1969) Operant conditioning of a profoundly retarded individual reinforced via a stomach fistula.
None. [IF=None, Cited=1, 5762261].