Liu, Hung-Wen

Publication with MISMATCHING institution:

Chen H, Zhao Z, Hallis TM, ..., Liu HW (2001) Insights into the Branched-Chain Formation of Mycarose: Methylation
Catalyzed by an (S)-Adenosylmethionine-Dependent Methyltransferase. Angewandte Chemie - International Edition.
[IF=2.456, Cited=0, 29712024].
Hou X, Feng J, Franklin JL, ..., Wang B (2024) Mechanistic Insights from the Crystal Structure and Computational
Analysis of the Radical SAM Deaminase DesII. Advanced Science. [IF=2.304, Cited=0, 38943270].
Kim HJ, LeVieux J, Yeh YC, Liu HW (2016) C3'-Deoxygenation of Paromamine Catalyzed by a Radical S-Adenosylmethionine
Enzyme: Characterization of the Enzyme AprD4 and Its Reductase Partner AprD3. Angewandte Chemie - International Edition.
[IF=2.456, Cited=0, 26879038].
Lin CI, McCarty RM, Liu HW (2017) The Enzymology of Organic Transformations: A Survey of Name Reactions in Biological
Systems. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 27505692].
Ren D, Wang SA, Ko Y, ..., Liu HW (2019) Identification of the C-Glycoside Synthases during Biosynthesis of the
Pyrazole-C-Nucleosides Formycin and Pyrazofurin. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 31518483].
Ushimaru R, Chen Z, Zhao H, ..., Liu HW (2020) Identification of the Enzymes Mediating the Maturation of the Seryl-tRNA
Synthetase Inhibitor SB-217452 during the Biosynthesis of Albomycins. Angewandte Chemie - International Edition.
[IF=2.456, Cited=0, 31863717].
Ren D, Kim M, Wang SA, Liu HW (2021) Identification of a Pyrrole Intermediate Which Undergoes C-Glycosidation and
Autoxidation to Yield the Final Product in Showdomycin Biosynthesis. Angewandte Chemie - International Edition.
[IF=2.456, Cited=0, 34048627].
Fan PH, Geng Y, Romo AJ, ..., Liu HW (2022) Two Radical SAM Enzymes Are Necessary and Sufficient for the In Vitro
Production of the Oxetane Nucleoside Antiviral Agent Albucidin. Angewandte Chemie - International Edition. [IF=2.456,
Cited=0, 36064953].
Zheng Z, Xiong J, Bu J, ..., Liu HW (2023) Reconstitution of the Final Steps in the Biosynthesis of Valanimycin Reveals
the Origin of Its Characteristic Azoxy Moiety. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 37963815].
Ushimaru R, Lin CI, Sasaki E, Liu HW (2016) Characterization of Enzymes Catalyzing Transformations of Cysteine
S-Conjugated Intermediates in the Lincosamide Biosynthetic Pathway. ChemBioChem. [IF=0.691, Cited=0, 27431934].
Ruszczycky MW, Liu HW (2015) Mechanistic Enzymology of the Radical SAM Enzyme DesII. Israel Journal of Chemistry.
[IF=0.673, Cited=0, 27635101].
Liu HW, Wei CC, Chen YJ, ..., Chang SJ (2016) Flavanol-rich lychee fruit extract alleviates diet-induced insulin
resistance via suppressing mTOR/SREBP-1 mediated lipogenesis in liver and restoring insulin signaling in skeletal
muscle. Molecular Nutrition and Food Research. [IF=1.094, Cited=0, 27161245].
Chang YC, Chen YT, Liu HW, ..., Chang SJ (2019) Oligonol Alleviates Sarcopenia by Regulation of Signaling Pathways
Involved in Protein Turnover and Mitochondrial Quality. Molecular Nutrition and Food Research. [IF=1.094, Cited=0, 30793867].
He W, Liu M, Li X, ..., Liu X (2016) Fungal biotransformation of tanshinone results in [4+2] cycloaddition with
sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity. Applied Microbiology and
Biotechnology. [IF=1.275, Cited=0, 27198724].
Liu HW, Chang YC, Chan YC, ..., Chang SJ (2020) Dysregulations of mitochondrial quality control and autophagic flux at
an early age lead to progression of sarcopenia in SAMP8 mice. Biogerontology. [IF=0.969, Cited=0, 32130580].
Ruszczycky MW, Liu HW (2017) Theory and Application of the Relationship Between Steady-State Isotope Effects on Enzyme
Intermediate Concentrations and Net Rate Constants. None. [IF=None, Cited=0, 28911781].
Thibodeaux CJ, Chang WC, Liu HW (2019) Unraveling flavoenzyme reaction mechanisms using flavin analogues and linear free
energy relationships. None. [IF=None, Cited=0, 31072486].
Lee YH, Liu HW (2022) Studies of GenK and OxsB, two B₁₂-dependent radical SAM enzymes involved in natural
product biosynthesis. None. [IF=None, Cited=0, 35644181].
Thibodeaux CJ, Liu HW (2017) The type II isopentenyl Diphosphate:Dimethylallyl diphosphate isomerase (IDI-2): A model
for acid/base chemistry in flavoenzyme catalysis. Archives of Biochemistry and Biophysics. [IF=0.874, Cited=0, 28577910].
Chang YC, Liu HW, Chan YC, ..., Chang SJ (2020) The green tea polyphenol epigallocatechin-3-gallate attenuates age-
associated muscle loss via regulation of miR-486-5p and myostatin. Archives of Biochemistry and Biophysics. [IF=0.874,
Cited=0, 32710883].
Liu HW, Cheng HC, Tsai SH, Shao YT (2022) Effects of acute resistance exercise with different loads on appetite,
appetite hormones and autonomic nervous system responses in healthy young men. Appetite. [IF=1.569, Cited=0, 36539159].
Lin WL, Chen JK, Wen X, ..., Liu HW (2022) DDX18 prevents R-loop-induced DNA damage and genome instability via PARP-1.
Cell Reports. [IF=1.738, Cited=0, 35858569].
Liu HW, Chan YC, Wei CC, ..., Chang SJ (2017) An alternative model for studying age-associated metabolic complications:
Senescence-accelerated mouse prone 8. None. [IF=None, Cited=0, 28843510].
Cheng HC, Tsai SH, Liu HW (2022) Activation of inflammatory pathways in PBMCs linking type 2 diabetes in older adults
without obesity. None. [IF=None, Cited=0, 35346761].
Tsai SH, Cheng HC, Liu HW (2022) Supervised high-load resistance training for improving muscle strength and quality in
prediabetic older adults: A pilot randomized controlled trial. Geriatric Nursing. [IF=0.836, Cited=0, 36375378].
Chang YC, Liu HW, Chen YT, ..., Chang SJ (2018) Resveratrol protects muscle cells against palmitate-induced cellular
senescence and insulin resistance through ameliorating autophagic flux. Journal of Food and Drug Analysis. [IF=1.532,
Cited=0, 29976399].
Liu HW, Mahmood S, Srinivasan M, ..., Patel MS (2013) Developmental programming in skeletal muscle in response to
overnourishment in the immediate postnatal life in rats. Journal of Nutritional Biochemistry. [IF=1.201, Cited=0, 23968580].
Chen TC, Liu HW, Russell A, ..., Nosaka K (2020) Large increases in plasma fast skeletal muscle troponin I after whole-
body eccentric exercises. Journal of Science and Medicine in Sport. [IF=1.612, Cited=0, 32067915].
Jeon BS, Huang TY, Ruszczycky MW, ..., Liu HW (2021) Byproduct formation during the biosynthesis of spinosyn A and
evidence for an enzymatic interplay to prevent its formation. Tetrahedron. [IF=0.579, Cited=0, 35685987].
Cammarata M, Lin KY, Pruet J, ..., Brodbelt J (2014) Probing the unfolding of myoglobin and domain C of PARP-1 with
covalent labeling and top-down ultraviolet photodissociation mass spectrometry. Analytical Chemistry. [IF=1.41,
Cited=0, 24484264].
Jeon BS, Wang SA, Ruszczycky MW, Liu HW (2016) Natural [4 + 2]-Cyclases. Chemical Reviews. [IF=11.712, Cited=0, 28441874].
Liu HW, Chan YC, Wang MF, ..., Chang SJ (2015) Dietary (-)-Epigallocatechin-3-gallate Supplementation Counteracts Aging-
Associated Skeletal Muscle Insulin Resistance and Fatty Liver in Senescence-Accelerated Mouse. Journal of Agricultural
and Food Chemistry. [IF=1.426, Cited=0, 26152236].
Liu CH, Wang SA, Ruszczycky MW, ..., Liu HW (2015) Studies of 1-Amino-2,2-difluorocyclopropane-1-carboxylic Acid:
Mechanism of Decomposition and Inhibition of 1-Aminocyclopropane-1-carboxylic Acid Deaminase. Organic Letters.
[IF=1.091, Cited=0, 26102233].
Ko Y, Wang SA, Ogasawara Y, ..., Liu HW (2017) Identification and Characterization of Enzymes Catalyzing
Pyrazolopyrimidine Formation in the Biosynthesis of Formycin A. Organic Letters. [IF=1.091, Cited=0, 28233490].
Jackson DR, Yu X, Wang G, ..., Tsai SC (2016) Insights into Complex Oxidation during BE-7585A Biosynthesis: Structural
Determination and Analysis of the Polyketide Monooxygenase BexE. ACS Chemical Biology. [IF=0.963, Cited=0, 26813028].
Agnihotri G, He S, Hong L, ..., Liu HW (2002) A revised mechanism for the inactivation of bovine liver enoyl-CoA
hydratase by (methylenecyclopropyl)formyl-CoA based on unexpected results with the C114A mutant. Biochemistry.
[IF=0.753, Cited=0, 11827529].
Chen H, Yamase H, Murakami K, ..., Liu HW (2002) Expression, purification, and characterization of two
N,N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine. Biochemistry.
[IF=0.753, Cited=0, 12119032].
Zhao Z, Chen H, Li K, ..., Liu HW (2003) Reaction of 1-amino-2-methylenecyclopropane-1-carboxylate with
1-aminocyclopropane-1-carboxylate deaminase: analysis and mechanistic implications. Biochemistry. [IF=0.753, Cited=0, 12590597].
Liu P, Liu A, Yan F, ..., Liu HW (2003) Biochemical and spectroscopic studies on (S)-2-hydroxypropylphosphonic acid
epoxidase: a novel mononuclear non-heme iron enzyme. Biochemistry. [IF=0.753, Cited=0, 14529267].
Zhao L, Beyer NJ, Borisova SA, Liu HW (2003) Beta-glucosylation as a part of self-resistance mechanism in
methymycin/pikromycin producing strain Streptomyces venezuelae. Biochemistry. [IF=0.753, Cited=0, 14674753].
Vogan EM, Bellamacina C, He X, ..., Petsko GA (2004) Crystal structure at 1.8 A resolution of CDP-D-glucose
4,6-dehydratase from Yersinia pseudotuberculosis. Biochemistry. [IF=0.753, Cited=0, 15023057].
Alam J, Beyer N, Liu HW (2004) Biosynthesis of colitose: expression, purification, and mechanistic characterization of
GDP-4-keto-6-deoxy-D-mannose-3-dehydrase (ColD) and GDP-L-colitose synthase (ColC). Biochemistry. [IF=0.753, Cited=0, 15610039].
Agnihotri G, Liu Yn, Paschal BM, Liu HW (2004) Identification of an unusual [2Fe-2S]-binding motif in the CDP-6-deoxy-D-
glycero-l-threo-4-hexulose-3-dehydrase from Yersinia pseudotuberculosis: implication for C-3 deoxygenation in the
biosynthesis of 3,6-dideoxyhexoses. Biochemistry. [IF=0.753, Cited=0, 15518577].
Karthikeyan S, Zhou Q, Zhao Z, ..., Zhang H (2004) Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate
deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening
reaction. Biochemistry. [IF=0.753, Cited=0, 15491139].
Zhang H, Zhou Y, Bao H, Liu HW (2006) Vi antigen biosynthesis in Salmonella typhi: characterization of UDP-N-
acetylglucosamine C-6 dehydrogenase (TviB) and UDP-N-acetylglucosaminuronic acid C-4 epimerase (TviC). Biochemistry.
[IF=0.753, Cited=0, 16800641].
Yan F, Munos JW, Liu P, Liu HW (2006) Biosynthesis of fosfomycin, re-examination and re-confirmation of a unique Fe(II)-
and NAD(P)H-dependent epoxidation reaction. Biochemistry. [IF=0.753, Cited=0, 16981707].
Melançon CE, Hong L, White JA, ..., Liu HW (2007) Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase
from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies.
Biochemistry. [IF=0.753, Cited=0, 17209568].
Borisova SA, Liu HW (2010) Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in
the methymycin/picromycin biosynthetic pathway. Biochemistry. [IF=0.753, Cited=0, 20695498].
Thibodeaux CJ, Liu HW (2011) Mechanistic studies of 1-aminocyclopropane-1-carboxylate deaminase: characterization of an
unusual pyridoxal 5'-phosphate-dependent reaction. Biochemistry. [IF=0.753, Cited=0, 21244019].
Wu Q, Liu YN, Chen H, ..., Liu HW (2007) A retro-evolution study of CDP-6-deoxy-D-glycero-L-threo-4-hexulose-3-dehydrase
(E1) from Yersinia pseudotuberculosis: implications for C-3 deoxygenation in the biosynthesis of 3,6-dideoxyhexoses.
Biochemistry. [IF=0.753, Cited=0, 17323931].
Kittleman W, Thibodeaux CJ, Liu Yn, ..., Liu HW (2007) Characterization and mechanistic studies of type II isopentenyl
diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus. Biochemistry. [IF=0.753, Cited=0, 17585782].
Yan F, Moon SJ, Liu P, ..., Liu HW (2007) Determination of the substrate binding mode to the active site iron of
(S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues. Biochemistry.
[IF=0.753, Cited=0, 17927218].
Thibodeaux CJ, Mansoorabadi SO, Kittleman W, ..., Liu HW (2008) Evidence for the involvement of acid/base chemistry in
the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus
aureus. Biochemistry. [IF=0.753, Cited=0, 18229948].
Smith P, Szu PH, Bui C, ..., Tsai SC (2008) Structure and mutagenic conversion of E1 dehydrase: at the crossroads of
dehydration, amino transfer, and epimerization. Biochemistry. [IF=0.753, Cited=0, 18491919].
Tao Z, Gao P, Hoffman D, ..., Liu HW (2008) Domain C of human poly(ADP-ribose) polymerase-1 is important for enzyme
activity and contains a novel zinc-ribbon motif. Biochemistry. [IF=0.753, Cited=51, 18452307].
Munos JW, Moon SJ, Mansoorabadi SO, ..., Liu HW (2008) Purification and characterization of the epoxidase catalyzing the
formation of fosfomycin from Pseudomonas syringae. Biochemistry. [IF=0.753, Cited=0, 18656958].
Tao Z, Gao P, Liu HW (2009) Studies of the expression of human poly(ADP-ribose) polymerase-1 in Saccharomyces cerevisiae
and identification of PARP-1 substrates by yeast proteome microarray screening. Biochemistry. [IF=0.753, Cited=0, 19877712].
Shen L, Wang Y, Lin CI, ..., Zhu XY (2014) Membrane environment can enhance the interaction of glycan binding protein to
cell surface glycan receptors. ACS Chemical Biology. [IF=0.963, Cited=0, 24949798].
Melançon CE, Thibodeaux CJ, Liu HW (2006) Glyco-stripping and glyco-swapping. ACS Chemical Biology. [IF=0.963, Cited=0, 17168536].
Thibodeaux CJ, Chang Wc, Liu HW (2011) Enzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.
Chemical Reviews. [IF=11.712, Cited=0, 22017381].
Lis L, Koltun ES, Liu HW, Kass SR (2002) Ring scission of diastereomeric 4-butylspiropentylcarbinyl radicals as a
chemical model for identifying enzyme-catalyzed FAD adducts resulting from spiropentylacetyl-CoA. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 11841297].
Leriche C, He X, Chang CWT, Liu HW (2003) Reversal of the apparent regiospecificity of NAD(P)H-dependent hydride
transfer: the properties of the difluoromethylene group, a carbonyl mimic. Journal of the American Chemical Society.
[IF=2.573, Cited=0, 12785757].
Beyer N, Alam J, Hallis TM, ..., Liu HW (2003) The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a
unique coenzyme B6-dependent enzyme. Journal of the American Chemical Society. [IF=2.573, Cited=0, 12733868].
Zhao Z, Hong L, Liu HW (2005) Characterization of protein encoded by spnR from the spinosyn gene cluster of
Saccharopolyspora spinosa: mechanistic implications for forosamine biosynthesis. Journal of the American Chemical
Society. [IF=2.573, Cited=0, 15913355].
Melançon CE, Takahashi H, Liu HW (2004) Characterization of tylM3/tylM2 and mydC/mycB pairs required for efficient
glycosyltransfer in macrolide antibiotic biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=0, 15612702].
Liu P, Mehn MP, Yan F, ..., Liu HW (2004) Oxygenase activity in the self-hydroxylation of (s)-2-hydroxypropylphosphonic
acid epoxidase involved in fosfomycin biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=0, 15315444].
Borisova SA, Zhao L, Melançon III CE, ..., Liu HW (2004) Characterization of the glycosyltransferase activity of desVII:
analysis of and implications for the biosynthesis of macrolide antibiotics. Journal of the American Chemical Society.
[IF=2.573, Cited=0, 15161264].
Takahashi H, Liu YN, Chen H, Liu HW (2005) Biosynthesis of TDP-l-mycarose: the specificity of a single enzyme governs
the outcome of the pathway. Journal of the American Chemical Society. [IF=2.573, Cited=0, 15984840].
Melançon CE, Yu Wl, Liu HW (2005) TDP-mycaminose biosynthetic pathway revised and conversion of desosamine pathway to
mycaminose pathway with one gene. Journal of the American Chemical Society. [IF=2.573, Cited=0, 16131199].
Takahashi H, Liu YN, Liu HW (2006) A two-stage one-pot enzymatic synthesis of TDP-L-mycarose from thymidine and
glucose-1-phosphate. Journal of the American Chemical Society. [IF=2.573, Cited=0, 16448097].
Kao CL, Borisova SA, Kim HJ, Liu HW (2006) Linear aglycones are the substrates for glycosyltransferase DesVII in
methymycin biosynthesis: analysis and implications. Journal of the American Chemical Society. [IF=2.573, Cited=0, 16637606].
Hong L, Zhao Z, Liu HW (2006) Characterization of SpnQ from the spinosyn biosynthetic pathway of Saccharopolyspora
spinosa: mechanistic and evolutionary implications for C-3 deoxygenation in deoxysugar biosynthesis. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 17076492].
Melançon CE, Liu HW (2007) Engineered biosynthesis of macrolide derivatives bearing the non-natural deoxysugars 4-epi-D-
mycaminose and 3-n-monomethylamino-3-deoxy-D-fucose. Journal of the American Chemical Society. [IF=2.573, Cited=0, 17388593].
Zhang H, White-Phillip JA, Melançon CE, ..., Liu HW (2007) Elucidation of the kijanimicin gene cluster: insights into
the biosynthesis of spirotetronate antibiotics and nitrosugars. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 17985890].
Kim HJ, Pongdee R, Wu Q, ..., Liu HW (2007) The biosynthesis of spinosyn in Saccharopolyspora spinosa: synthesis of the
cross-bridging precursor and identification of the function of SpnJ. Journal of the American Chemical Society.
[IF=2.573, Cited=0, 17985910].
Hong L, Zhao Z, Melançon CE, ..., Liu HW (2008) In vitro characterization of the enzymes involved in TDP-D-forosamine
biosynthesis in the spinosyn pathway of Saccharopolyspora spinosa. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 18345667].
Sasaki E, Ogasawara Y, Liu HW (2010) A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type
natural product. Journal of the American Chemical Society. [IF=2.573, Cited=0, 20443562].
Thibodeaux CJ, Chang Wc, Liu HW (2010) Linear free energy relationships demonstrate a catalytic role for the flavin
mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 20593767].
Sasaki E, Liu HW (2010) Mechanistic studies of the biosynthesis of 2-thiosugar: evidence for the formation of an enzyme-
bound 2-ketohexose intermediate in BexX-catalyzed reaction. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 20961106].
Ruszczycky MW, Choi Sh, Mansoorabadi SO, Liu HW (2011) Mechanistic studies of the radical S-adenosyl-L-methionine enzyme
DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose.
Journal of the American Chemical Society. [IF=2.573, Cited=0, 21513273].
Yun D, Dey M, Higgins LJ, ..., Drennan CL (2011) Structural basis of regiospecificity of a mononuclear iron enzyme in
antibiotic fosfomycin biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=0, 21682308].
Choi Sh, Mansoorabadi SO, Liu Yn, ..., Liu HW (2012) Analysis of UDP-D-apiose/UDP-D-xylose synthase-catalyzed conversion
of UDP-D-apiose phosphonate to UDP-D-xylose phosphonate: implications for a retroaldol-aldol mechanism. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 22830643].
Huang H, Chang Wc, Pai PJ, ..., Liu HW (2012) Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl
and methylenecyclopropyl substrate analogues. Journal of the American Chemical Society. [IF=2.573, Cited=0, 23006053].
Sasaki E, Lin CI, Lin KY, Liu HW (2012) Construction of the octose 8-phosphate intermediate in lincomycin A
biosynthesis: characterization of the reactions catalyzed by LmbR and LmbN. Journal of the American Chemical Society.
[IF=2.573, Cited=0, 22989310].
Kim HJ, McCarty RM, Ogasawara Y, ..., Liu HW (2013) GenK-catalyzed C-6' methylation in the biosynthesis of gentamicin:
isolation and characterization of a cobalamin-dependent radical SAM enzyme. Journal of the American Chemical Society.
[IF=2.573, Cited=0, 23679096].
Chang Wc, Mansoorabadi SO, Liu HW (2013) Reaction of HppE with substrate analogues: evidence for carbon-phosphorus bond
cleavage by a carbocation rearrangement. Journal of the American Chemical Society. [IF=2.573, Cited=0, 23672451].
Al-Mestarihi A, Romo A, Liu HW, Bachmann BO (2013) Nitrososynthase-triggered oxidative carbon-carbon bond cleavage in
baumycin biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=0, 23885759].
Huang H, Chang WC, Lin GM, ..., Liu HW (2014) Mechanistic consequences of chiral radical clock probes: analysis of the
mononuclear non-heme iron enzyme HppE with 2-hydroxy-3-methylenecyclopropyl radical clock substrates. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 24512048].
Lin CI, Sasaki E, Zhong A, Liu HW (2014) In vitro characterization of LmbK and LmbO: identification of GDP-D-erythro-α-
D-gluco-octose as a key intermediate in lincomycin A biosynthesis. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 24380627].
Hashimoto T, Hashimoto J, Teruya K, ..., Kuzuyama T (2015) Biosynthesis of versipelostatin: identification of an enzyme-
catalyzed [4+2]-cycloaddition required for macrocyclization of spirotetronate-containing polyketides. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 25551461].
Yuan Y, Bleile DW, Wen X, ..., Pinto BM (2008) Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-
galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations. Journal of the American
Chemical Society. [IF=2.573, Cited=0, 18278916].
Mirica LM, McCusker KP, Munos JW, ..., Klinman JP (2008) 18O kinetic isotope effects in non-heme iron enzymes: probing
the nature of Fe/O2 intermediates. Journal of the American Chemical Society. [IF=2.573, Cited=0, 18540575].
Munos JW, Pu X, Mansoorabadi SO, ..., Liu HW (2009) A secondary kinetic isotope effect study of the 1-deoxy-D-
xylulose-5-phosphate reductoisomerase-catalyzed reaction: evidence for a retroaldol-aldol rearrangement. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 19159292].
Szu PH, Ruszczycky MW, Choi Sh, ..., Liu HW (2009) Characterization and mechanistic studies of DesII: a radical
S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine. Journal of the American Chemical
Society. [IF=2.573, Cited=0, 19746907].
Tao Z, Gao P, Liu HW (2009) Identification of the ADP-ribosylation sites in the PARP-1 automodification domain: analysis
and implications. Journal of the American Chemical Society. [IF=2.573, Cited=0, 19764761].
Ogasawara Y, Liu HW (2009) Biosynthetic studies of aziridine formation in azicemicins. Journal of the American Chemical
Society. [IF=2.573, Cited=0, 19928906].
Ruszczycky MW, Choi SH, Liu HW (2010) Stoichiometry of the redox neutral deamination and oxidative dehydrogenation
reactions catalyzed by the radical SAM enzyme DesII. Journal of the American Chemical Society. [IF=2.573, Cited=0, 20121093].
Kim HJ, White-Phillip JA, Ogasawara Y, ..., Liu HW (2010) Biosynthesis of spinosyn in Saccharopolyspora spinosa:
synthesis of permethylated rhamnose and characterization of the functions of SpnH, SpnI, and SpnK. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 20158237].
Yeh YC, Kim HJ, Liu HW (2021) Mechanistic Investigation of 1,2-Diol Dehydration of Paromamine Catalyzed by the Radical
S-Adenosyl-l-methionine Enzyme AprD4. Journal of the American Chemical Society. [IF=2.573, Cited=0, 33784078].
Besandre RA, Chen Z, Davis I, ..., Liu HW (2021) HygY Is a Twitch Radical SAM Epimerase with Latent Dehydrogenase
Activity Revealed upon Mutation of a Single Cysteine Residue. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 34491039].
Choi SH, Jeon B, Kim N, ..., Liu HW (2021) Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the
Biosynthesis of Spinosyn A. Journal of the American Chemical Society. [IF=2.573, Cited=0, 34813308].
Lee YH, Hou X, Chen R, ..., Liu HW (2022) Radical S-Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated
1,2-Diol Dehydration during the Biosynthesis of Blasticidin S. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 35238201].
Zhang J, Hou X, Chen Z, ..., Liu HW (2022) Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a
Twitch Radical S-Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 35622017].
Ren D, Lee YH, Wang SA, Liu HW (2022) Characterization of the Oxazinomycin Biosynthetic Pathway Revealing the Key Role
of a Nonheme Iron-Dependent Mono-oxygenase. Journal of the American Chemical Society. [IF=2.573, Cited=0, 35687050].
Lee YH, Yeh YC, Fan PH, ..., Liu HW (2023) Changing Fates of the Substrate Radicals Generated in the Active Sites of the
B₁₂-Dependent Radical SAM Enzymes OxsB and AlsB. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 36719327].
Zheng Z, Clardy J, Liu HW (2024) Biosynthesis of the Unusual Epoxy Isonitrile-Containing Antibiotics Aerocyanidin and
Amycomicin. Journal of the American Chemical Society. [IF=2.573, Cited=0, 39039999].
Lin GM, Choi SH, Ruszczycky MW, Liu HW (2015) Mechanistic Investigation of the Radical S-Adenosyl-L-methionine Enzyme
DesII Using Fluorinated Analogues. Journal of the American Chemical Society. [IF=2.573, Cited=0, 25826575].
Patel A, Chen Z, Yang Z, ..., Singleton DA (2016) Dynamically Complex [6+4] and [4+2] Cycloadditions in the Biosynthesis
of Spinosyn A. Journal of the American Chemical Society. [IF=2.573, Cited=0, 26909570].
Lin GM, Romo AJ, Liem PH, ..., Liu HW (2017) Identification and Interrogation of the Herbicidin Biosynthetic Gene
Cluster: First Insight into the Biosynthesis of a Rare Undecose Nucleoside Antibiotic. Journal of the American Chemical
Society. [IF=2.573, Cited=0, 29111702].
Kim HJ, Liu YN, McCarty RM, Liu HW (2017) Reaction Catalyzed by GenK, a Cobalamin-Dependent Radical S-Adenosyl-l-
methionine Methyltransferase in the Biosynthetic Pathway of Gentamicin, Proceeds with Retention of Configuration.
Journal of the American Chemical Society. [IF=2.573, Cited=0, 29091410].
Ushimaru R, Ruszczycky MW, Chang WC, ..., Liu HW (2018) Substrate Conformation Correlates with the Outcome of
Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions. Journal of the American Chemical Society. [IF=2.573, Cited=0, 29870653].
Ushimaru R, Ruszczycky MW, Liu HW (2018) Changes in Regioselectivity of H Atom Abstraction during the Hydroxylation and
Cyclization Reactions Catalyzed by Hyoscyamine 6β-Hydroxylase. Journal of the American Chemical Society. [IF=2.573,
Cited=0, 30545219].
Ushimaru R, Liu HW (2019) Biosynthetic Origin of the Atypical Stereochemistry in the Thioheptose Core of Albomycin
Nucleoside Antibiotics. Journal of the American Chemical Society. [IF=2.573, Cited=0, 30673214].
Liu HW, Tsai YT, Chang SJ (2014) Toona sinensis leaf extract inhibits lipid accumulation through up-regulation of genes
involved in lipolysis and fatty acid oxidation in adipocytes. Journal of Agricultural and Food Chemistry. [IF=1.426,
Cited=0, 24884355].
Zhao Z, Liu HW (2002) Synthesis of labeled 1-amino-2-methylenecyclopropane-1-carboxylic acid, an inactivator of
1-aminocyclopropane-1-carboxylate deaminase. Journal of Organic Chemistry. [IF=0.885, Cited=0, 11950295].
Mansoorabadi SO, Thibodeaux CJ, Liu HW (2007) The diverse roles of flavin coenzymes--nature's most versatile thespians.
Journal of Organic Chemistry. [IF=0.885, Cited=0, 17580897].
Liautard V, Desvergnes V, Itoh K, ..., Martin OR (2008) Convergent and stereoselective synthesis of iminosugar-
containing Galf and UDP-Galf mimicks: evaluation as inhibitors of UDP-Gal mutase. Journal of Organic Chemistry.
[IF=0.885, Cited=0, 18358048].
Wong A, Munos JW, Devasthali V, ..., Liu HW (2004) Study of 1-deoxy-D-xylulose-5-phosphate reductoisomerase: synthesis
and evaluation of fluorinated substrate analogues. Organic Letters. [IF=1.091, Cited=0, 15387564].
Kao Cl, Kittleman W, Zhang H, ..., Liu HW (2005) Stereochemical analysis of isopentenyl diphosphate isomerase type II
from Staphylococcus aureus using chemically synthesized (S)- and (R)-[2-2H]isopentenyl diphosphates. Organic Letters.
[IF=1.091, Cited=0, 16321020].
Itoh K, Huang Z, Liu HW (2007) Synthesis and analysis of substrate analogues for UDP-galactopyranose mutase: implication
for an oxocarbenium ion intermediate in the catalytic mechanism. Organic Letters. [IF=1.091, Cited=0, 17266324].
Xiao Y, Chang Wc, Liu HW, Liu P (2011) Study of IspH, a key enzyme in the methylerythritol phosphate pathway using
fluoro-substituted substrate analogues. Organic Letters. [IF=1.091, Cited=0, 21981393].
Ruszczycky MW, Liu HW (2017) Biochemistry: The surprising history of an antioxidant. Nature. [IF=11.591, Cited=0, 29094692].
Sasaki E, Zhang X, Sun HG, ..., Liu HW (2014) Co-opting sulphur-carrier proteins from primary metabolic pathways for
2-thiosugar biosynthesis. Nature. [IF=11.591, Cited=0, 24814342].
Bridwell-Rabb J, Zhong A, Sun HG, ..., Liu HW (2017) A B₁₂-dependent radical SAM enzyme involved in
oxetanocin A biosynthesis. Nature. [IF=11.591, Cited=0, 28346939].
Huang C, Yang C, Zhang W, ..., Zhang C (2018) Molecular basis of dimer formation during the biosynthesis of
benzofluorene-containing atypical angucyclines. Nature Communications. [IF=3.268, Cited=0, 29802272].
De BC, Zhang W, Yang C, ..., Zhang C (2022) Flavin-enabled reductive and oxidative epoxide ring opening reactions.
Nature Communications. [IF=3.268, Cited=0, 35986005].
Ban YH, Song MC, Hwang JY, ..., Yoon YJ (2019) Complete reconstitution of the diverse pathways of gentamicin B
biosynthesis. Nature Chemical Biology. [IF=2.623, Cited=0, 30643280].
Ban YH, Song MC, Hwang JY, ..., Yoon YJ (2019) Author Correction: Complete reconstitution of the diverse pathways of
gentamicin B biosynthesis. Nature Chemical Biology. [IF=2.623, Cited=0, 30728495].
Ban YH, Song MC, Hwang JY, ..., Yoon YJ (2020) Publisher Correction: Complete reconstitution of the diverse pathways of
gentamicin B biosynthesis. Nature Chemical Biology. [IF=2.623, Cited=0, 32488179].
Liu HW, Huang WC, Yu WJ, Chang SJ (2015) Toona Sinensis ameliorates insulin resistance via AMPK and PPARγ pathways. Food
and Function. [IF=1.281, Cited=0, 25940430].
Liu HW, Wei CC, Chang SJ (2016) Low-molecular-weight polyphenols protect kidney damage through suppressing NF-κB and
modulating mitochondrial biogenesis in diabetic db/db mice. Food and Function. [IF=1.281, Cited=0, 26960417].
Ruszczycky MW, Zhong A, Liu HW (2018) Following the electrons: peculiarities in the catalytic cycles of radical SAM
enzymes. Natural Product Reports. [IF=3.292, Cited=0, 29485151].
Zhang Q, Li H, Yu L, ..., Zhang C (2017) Characterization of the flavoenzyme XiaK as an N-hydroxylase and
implications in indolosesquiterpene diversification. Chemical Science. [IF=1.563, Cited=0, 28970893].
Lee YH, Ren D, Jeon B, Liu HW (2023) S-Adenosylmethionine: more than just a methyl donor. Natural Product
Reports. [IF=3.292, Cited=0, 36891755].
Ruszczycky MW, Choi Sh, Liu HW (2013) EPR-kinetic isotope effect study of the mechanism of radical-mediated
dehydrogenation of an alcohol by the radical SAM enzyme DesII. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=0, 23329328].
Caldara-Festin G, Jackson DR, Barajas JF, ..., Tsai SC (2015) Structural and functional analysis of two di-domain
aromatase/cyclases from type II polyketide synthases. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=0, 26631750].
Bridwell-Rabb J, Kang G, Zhong A, ..., Drennan CL (2016) An HD domain phosphohydrolase active site tailored for
oxetanocin-A biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=0, 27849620].
Jeon BS, Ruszczycky MW, Russell WK, ..., Liu HW (2017) Investigation of the mechanism of the SpnF-catalyzed
[4+2]-cycloaddition reaction in the biosynthesis of spinosyn A. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=0, 28874588].
Yang Z, Yang S, Yu P, ..., Houk KN (2018) Influence of water and enzyme SpnF on the dynamics and energetics of the
ambimodal [6+4]/[4+2] cycloaddition. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=0, 29348209].
Ren D, Ruszczycky MW, Ko Y, ..., Liu HW (2020) Characterization of the coformycin biosynthetic gene cluster in
Streptomyces kaniharaensis. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=0, 32350138].
Lin TY, Cheng HC, Tsai YL, ..., Hung TM (2023) Effects of resistance exercises on inhibitory control and plasma
epinephrine levels: A registered report of a crossover randomized controlled trial. None. [IF=None, Cited=0, 38095293].
Tsai SH, Cheng HC, Liu HW (2021) Effects of volume-matched resistance training with different loads on glycemic control,
inflammation, and body composition in prediabetic older adults. None. [IF=None, Cited=0, 34265211].
Zhao L, Chang Wc, Xiao Y, ..., Liu P (2013) Methylerythritol phosphate pathway of isoprenoid biosynthesis. Annual Review
of Biochemistry. [IF=5.273, Cited=0, 23746261].
He XM, Liu HW (2001) Formation of unusual sugars: mechanistic studies and biosynthetic applications. Annual Review of
Biochemistry. [IF=5.273, Cited=0, 12045109].
Liu HW, Srinivasan M, Mahmood S, ..., Patel MS (2013) Adult-onset obesity induced by early life overnutrition could be
reversed by moderate caloric restriction. American Journal of Physiology - Endocrinology and Metabolism. [IF=1.181,
Cited=0, 23900419].
Liu HW, Cheng HC, Tsai SH, Sun WH (2020) Effect of Progressive Resistance Training on Circulating Adipogenesis-,
Myogenesis-, and Inflammation-Related microRNAs in Healthy Older Adults: An Exploratory Study. Gerontology. [IF=1.404,
Cited=0, 33022678].
Liu HW, Kao HH, Wu CH (2019) Exercise training upregulates SIRT1 to attenuate inflammation and metabolic dysfunction in
kidney and liver of diabetic db/db mice. Nutrition and Metabolism. [IF=1.166, Cited=0, 30988688].
Lin TY, Cheng HC, Liu HW, Hung TM (2024) Exploring Temporal and Intensity Effects of Resistance Exercise on Inhibition:
A Four-Arm Crossover Randomized Controlled Trial. Psychology Research and Behavior Management. [IF=1.346, Cited=0, 38745911].
Lin TY, Liu HW, Hung TM (2021) The Ketogenic Effect of Medium-Chain Triacylglycerides. Frontiers in Nutrition.
[IF=1.143, Cited=0, 34888335].
Liu HW, Chang SJ (2018) Moderate Exercise Suppresses NF-κB Signaling and Activates the SIRT1-AMPK-PGC1α Axis to
Attenuate Muscle Loss in Diabetic db/db Mice. Frontiers in Physiology. [IF=1.197, Cited=0, 29896118].
Liu HW, Chen YJ, Chang YC, Chang SJ (2017) Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates
Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1. Nutrients. [IF=1.55, Cited=0, 28930190].

Publication with MISSING institution:

Zhao Z, Liu P, Murakami K, ..., Liu HW (2002) Mechanistic studies of HPP epoxidase: configuration of the substrate
governs its enzymatic fate. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 12458528].
Karthikeyan S, Zhao Z, Kao CL, ..., Liu HW (2004) Structural analysis of 1-aminocyclopropane-1-carboxylate deaminase:
observation of an aminyl intermediate and identification of Tyr 294 as the active-site nucleophile. Angewandte Chemie -
International Edition. [IF=2.456, Cited=0, 15221829].
Szu Ph, He X, Zhao L, Liu HW (2005) Biosynthesis of TDP-D-desosamine: identification of a strategy for C4 deoxygenation.
Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 16187386].
Borisova SA, Zhang C, Takahashi H, ..., Liu HW (2006) Substrate specificity of the macrolide-glycosylating enzyme pair
DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angewandte Chemie - International Edition.
[IF=2.456, Cited=0, 16538696].
Thibodeaux CJ, Melançon CE, Liu HW (2008) Natural-product sugar biosynthesis and enzymatic glycodiversification.
Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 19058170].
Lehwald P, Richter M, Röhr C, ..., Müller M (2010) Enantioselective intermolecular aldehyde-ketone cross-coupling
through an enzymatic carboligation reaction. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 20191639].
Chang Wc, Xiao Y, Liu HW, Liu P (2011) Mechanistic studies of an IspH-catalyzed reaction: implications for substrate
binding and protonation in the biosynthesis of isoprenoids. Angewandte Chemie - International Edition. [IF=2.456,
Cited=0, 22025241].
Kim HJ, Choi Sh, Jeon Bs, ..., Liu HW (2014) Chemoenzymatic synthesis of spinosyn A. Angewandte Chemie - International
Edition. [IF=2.456, Cited=0, 25287333].
Ko Y, Ruszczycky MW, Choi SH, Liu HW (2014) Mechanistic studies of the radical S-adenosylmethionine enzyme DesII with
TDP-D-fucose. Angewandte Chemie - International Edition. [IF=2.456, Cited=0, 25418063].
Molitor EJ, Paschal BM, Liu HW (2003) Cyclopropane fatty acid synthase from Escherichia coli: enzyme purification and
inhibition by vinylfluorine and epoxide-containing substrate analogues. ChemBioChem. [IF=0.691, Cited=0, 14661280].
Borisova SA, Kim HJ, Pu X, Liu HW (2008) Glycosylation of acyclic and cyclic aglycone substrates by macrolide
glycosyltransferase DesVII/DesVIII: analysis and implications. ChemBioChem. [IF=0.691, Cited=0, 18548476].
Calveras J, Thibodeaux CJ, Mansoorabadi SO, Liu HW (2011) Stereochemical studies of the type II isopentenyl diphosphate-
dimethylallyl diphosphate isomerase implicate the FMN coenzyme in substrate protonation. ChemBioChem. [IF=0.691,
Cited=0, 22135039].
Rocklin AM, Kato K, Liu HW, ..., Lipscomb JD (2004) Mechanistic studies of 1-aminocyclopropane-1-carboxylic acid
oxidase: single turnover reaction. Journal of Biological Inorganic Chemistry. [IF=0.755, Cited=0, 14714198].
White-Phillip J, Thibodeaux CJ, Liu HW (2009) Enzymatic synthesis of TDP-deoxysugars. None. [IF=None, Cited=0, 19362653].
Yan F, Li T, Lipscomb JD, ..., Liu HW (2005) Site-directed mutagenesis and spectroscopic studies of the iron-binding
site of (S)-2-hydroxypropylphosphonic acid epoxidase. Archives of Biochemistry and Biophysics. [IF=0.874, Cited=0, 16150418].
Romo AJ, Liu HW (2011) Mechanisms and structures of vitamin B(6)-dependent enzymes involved in deoxy sugar biosynthesis.
None. [IF=None, Cited=0, 21315852].
Ruszczycky MW, Ogasawara Y, Liu HW (2011) Radical SAM enzymes in the biosynthesis of sugar-containing natural products.
None. [IF=None, Cited=0, 22172915].
Huang Z, Zhang Q, Liu HW (2003) Reconstitution of UDP-galactopyranose mutase with 1-deaza-FAD and 5-deaza-FAD: analysis
and mechanistic implications. Bioorganic Chemistry. [IF=1.325, Cited=0, 14613770].
Pongdee R, Liu HW (2004) Elucidation of enzyme mechanisms using fluorinated substrate analogues. Bioorganic Chemistry.
[IF=1.325, Cited=0, 15381404].
Desvergnes S, Desvergnes V, Martin OR, ..., Py S (2007) Stereoselective synthesis of beta-1-C-substituted
1,4-dideoxy-1,4-imino-D-galactitols and evaluation as UDP-galactopyranose mutase inhibitors. Bioorganic and Medicinal
Chemistry. [IF=0.86, Cited=0, 17662609].
Munos JW, Pu X, Liu HW (2007) Synthesis and analysis of a fluorinated product analogue as an inhibitor for 1-deoxy-D-
xylulose 5-phosphate reductoisomerase. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=0, 18078746].
Kim HJ, Ruszczycky MW, Liu HW (2012) Current developments and challenges in the search for a naturally selected Diels-
Alderase. Current Opinion in Chemical Biology. [IF=1.51, Cited=0, 22260931].
Chang Wc, Song H, Liu HW, Liu P (2013) Current development in isoprenoid precursor biosynthesis and regulation. Current
Opinion in Chemical Biology. [IF=1.51, Cited=0, 23891475].
Chang CWT, Liu HW (2002) Synthesis of TDP-3-amino-3,4,6-trideoxy-alpha-D-xylo-hexopyranose--the immediate precursor of
TDP-alpha-D-desosamine. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=0, 12031327].
Agnihotri G, Liu HW (2003) Enoyl-CoA hydratase. reaction, mechanism, and inhibition. Bioorganic and Medicinal Chemistry.
[IF=0.86, Cited=0, 12467702].
He X, Liu HW (2002) Mechanisms of enzymatic CbondO bond cleavages in deoxyhexose biosynthesis. Current Opinion in
Chemical Biology. [IF=1.51, Cited=0, 12413542].
Zhong A, Lee YH, Liu YN, Liu HW (2021) Biosynthesis of Oxetanocin-A Includes a B₁₂-Dependent Radical SAM
Enzyme That Can Catalyze both Oxidative Ring Contraction and the Demethylation of SAM. Biochemistry. [IF=0.753,
Cited=0, 33560833].
Ko Y, Lin GM, Ruszczycky MW, Liu HW (2018) Mechanistic Implications of the Deamination of TDP-4-amino-4-deoxy-d-fucose
Catalyzed by the Radical SAM Enzyme DesII. Biochemistry. [IF=0.753, Cited=0, 29473739].
Pan HX, Chen Z, Zeng T, ..., Tang GL (2019) Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its
Structural Diversity. Organic Letters. [IF=1.091, Cited=0, 30763106].
Sato S, Fan PH, Yeh YC, Liu HW (2024) Complete In Vitro Reconstitution of the Apramycin Biosynthetic Pathway
Demonstrates the Unusual Incorporation of a β-d-Sugar Nucleotide in the Final Glycosylation Step. Journal of the
American Chemical Society. [IF=2.573, Cited=0, 38546392].
Wang SA, Ko Y, Zeng J, ..., Liu HW (2019) Identification of the Formycin A Biosynthetic Gene Cluster from Streptomyces
kaniharaensis Illustrates the Interplay between Biological Pyrazolopyrimidine Formation and de Novo Purine Biosynthesis.
Journal of the American Chemical Society. [IF=2.573, Cited=0, 30942582].
Higgins LJ, Yan F, Liu P, ..., Drennan CL (2005) Structural insight into antibiotic fosfomycin biosynthesis by a
mononuclear iron enzyme. Nature. [IF=11.591, Cited=0, 16015285].
Thibodeaux CJ, Melançon CE, Liu HW (2007) Unusual sugar biosynthesis and natural product glycodiversification. Nature.
[IF=11.591, Cited=0, 17460661].
Kim HJ, Ruszczycky MW, Choi Sh, ..., Liu HW (2011) Enzyme-catalysed [4+2] cycloaddition is a key step in the
biosynthesis of spinosyn A. Nature. [IF=11.591, Cited=0, 21544146].
Chang Wc, Dey M, Liu P, ..., Liu HW (2013) Mechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-
migration reaction. Nature. [IF=11.591, Cited=0, 23552950].
Choi Sh, Ruszczycky MW, Zhang H, Liu HW (2011) A fluoro analogue of UDP-α-D-glucuronic acid is an inhibitor of UDP-α-D-
apiose/UDP-α-D-xylose synthase. Chemical Communications. [IF=0.902, Cited=0, 21826368].
Lin CI, McCarty RM, Liu HW (2013) The biosynthesis of nitrogen-, sulfur-, and high-carbon chain-containing sugars.
Chemical Society Reviews. [IF=8.116, Cited=0, 23348524].
Sun HG, Ruszczycky MW, Chang WC, ..., Liu HW (2011) Nucleophilic participation of reduced flavin coenzyme in mechanism
of UDP-galactopyranose mutase. Journal of Biological Chemistry. [IF=1.122, Cited=0, 22187430].
Koropatkin NM, Liu HW, Holden HM (2003) High resolution x-ray structure of tyvelose epimerase from Salmonella typhi.
Journal of Biological Chemistry. [IF=1.122, Cited=0, 12642575].
Vasicek L, O'Brien JP, Browning KS, ..., Brodbelt JS (2012) Mapping protein surface accessibility via an electron
transfer dissociation selectively cleavable hydrazone probe. Molecular and Cellular Proteomics. [IF=1.296, Cited=2, 22393264].
Kuo YA, Chen YI, Wang Y, ..., Yeh HC (2024) Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing
Platform. None. [IF=None, Cited=0, 39026723].
Smith P, Lin A, Szu Ph, ..., Tsai SC (2006) Biosynthesis of a 3,6-dideoxyhexose: crystallization and X-ray diffraction
of CDP-6-deoxy-L-threo-D-glycero-4-hexulose-3-dehydrase (E1) for ascarylose biosynthesis. None. [IF=None, Cited=0, 16511309].
Vogan EM, Bellamacina CR, He X, ..., Petsko GA (2002) Purification, crystallization and molecular symmetry of CDP-D-
glucose 4,6-dehydratase from Yersinia pseudotuberculosis. None. [IF=None, Cited=0, 11807280].

Liu, Hung-Wen

Publication with MATCHING institution:

Publication with MISMATCHING institution:

Publication with MISSING institution: