Kahne, Dan

Publication with MATCHING institution:

Thomas C, Aller SG, Beis K, ..., Tampé R (2020) Structural and functional diversity calls for a new classification of
ABC transporters. FEBS Letters. [IF=0.871, Cited=108, 32978974].
Park Y, Taguchi A, Baidin V, ..., Walker S (2023) A Time-Resolved FRET Assay Identifies a Small Molecule that Inhibits
the Essential Bacterial Cell Wall Polymerase FtsW. Angewandte Chemie - International Edition. [IF=2.456, Cited=1, 37099323].
Melnyk S, Stepanyshyn A, Yushchuk O, ..., Ostash B (2022) Genetic approaches to improve clorobiocin production in
Streptomyces roseochromogenes NRRL 3504. Applied Microbiology and Biotechnology. [IF=1.275, Cited=2, 35147743].
Skinner KA, Wzorek JS, Kahne D, Gaudet R (2021) Efficient and flexible synthesis of new photoactivatable propofol
analogs. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=0, 33705906].
Taguchi A, Kahne D, Walker S (2019) Chemical tools to characterize peptidoglycan synthases. Current Opinion in Chemical
Biology. [IF=1.51, Cited=12, 31466035].
Tomasek D, Kahne D (2021) The assembly of β-barrel outer membrane proteins. Current Opinion in Microbiology. [IF=1.52,
Cited=34, 33561734].
Lundstedt E, Kahne D, Ruiz N (2020) Assembly and Maintenance of Lipids at the Bacterial Outer Membrane. Chemical
Reviews. [IF=11.712, Cited=52, 32955879].
Kumar S, Mollo A, Kahne D, Ruiz N (2022) The Bacterial Cell Wall: From Lipid II Flipping to Polymerization. Chemical
Reviews. [IF=11.712, Cited=19, 35274942].
Moison E, Xie R, Zhang G, ..., Kahne D (2017) A Fluorescent Probe Distinguishes between Inhibition of Early and Late
Steps of Lipopolysaccharide Biogenesis in Whole Cells. ACS Chemical Biology. [IF=0.963, Cited=11, 28248483].
Lee W, Do T, Zhang G, ..., Walker S (2018) Antibiotic Combinations That Enable One-Step, Targeted Mutagenesis of
Chromosomal Genes. ACS Infectious Diseases. [IF=0.991, Cited=9, 29534563].
Losey HC, Peczuh MW, Chen Z, ..., Walsh CT (2001) Tandem action of glycosyltransferases in the maturation of vancomycin
and teicoplanin aglycones: novel glycopeptides. Biochemistry. [IF=0.753, Cited=88, 11294642].
Freel Meyers CL, Oberthür M, Anderson JW, ..., Walsh CT (2003) Initial characterization of novobiocic acid noviosyl
transferase activity of NovM in biosynthesis of the antibiotic novobiocin. Biochemistry. [IF=0.753, Cited=23, 12680772].
Lu W, Leimkuhler C, Oberthür M, ..., Walsh CT (2004) AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the
anthracycline aclacinomycin A. Biochemistry. [IF=0.753, Cited=29, 15078101].
Pacholec M, Freel Meyers CL, Oberthür M, ..., Walsh CT (2005) Characterization of the aminocoumarin ligase SimL from the
simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway. Biochemistry. [IF=0.753,
Cited=18, 15779922].
Freel Meyers CL, Oberthür M, Heide L, ..., Walsh CT (2004) Assembly of dimeric variants of coumermycins by tandem action
of the four biosynthetic enzymes CouL, CouM, CouP, and NovN. Biochemistry. [IF=0.753, Cited=20, 15554710].
Garneau-Tsodikova S, Stapon A, Kahne D, ..., Walsh CT (2006) Installation of the pyrrolyl-2-carboxyl pharmacophore by
CouN1 and CouN7 in the late biosynthetic steps of the aminocoumarin antibiotics clorobiocin and coumermycin A1.
Biochemistry. [IF=0.753, Cited=17, 16834331].
Chng SS, Gronenberg LS, Kahne D (2010) Proteins required for lipopolysaccharide assembly in Escherichia coli form a
transenvelope complex. Biochemistry. [IF=0.753, Cited=97, 20446753].
Hagan CL, Kahne D (2011) The reconstituted Escherichia coli Bam complex catalyzes multiple rounds of β-barrel assembly.
Biochemistry. [IF=0.753, Cited=37, 21823654].
Freinkman E, Okuda S, Ruiz N, Kahne D (2012) Regulated assembly of the transenvelope protein complex required for
lipopolysaccharide export. Biochemistry. [IF=0.753, Cited=87, 22668317].
Hagan CL, Westwood DB, Kahne D (2013) bam Lipoproteins Assemble BamA in vitro. Biochemistry. [IF=0.753, Cited=46, 23919461].
Fridman M, Balibar CJ, Lupoli T, ..., Garneau-Tsodikova S (2007) Chemoenzymatic formation of novel aminocoumarin
antibiotics by the enzymes CouN1 and CouN7. Biochemistry. [IF=0.753, Cited=20, 17580964].
Ostash B, Doud EH, Lin C, ..., Walker S (2009) Complete characterization of the seventeen step moenomycin biosynthetic
pathway. Biochemistry. [IF=0.753, Cited=45, 19640006].
Fuse S, Tsukamoto H, Yuan Y, ..., Kahne D (2010) Functional and structural analysis of a key region of the cell wall
inhibitor moenomycin. ACS Chemical Biology. [IF=0.963, Cited=15, 20496948].
Rebets Y, Lupoli T, Qiao Y, ..., Walker S (2013) Moenomycin resistance mutations in Staphylococcus aureus reduce
peptidoglycan chain length and cause aberrant cell division. ACS Chemical Biology. [IF=0.963, Cited=32, 24255971].
Ruiz N, Wu T, Kahne D, Silhavy TJ (2006) Probing the barrier function of the outer membrane with chemical
conditionality. ACS Chemical Biology. [IF=0.963, Cited=52, 17163776].
Yuan Y, Fuse S, Ostash B, ..., Walker S (2008) Structural analysis of the contacts anchoring moenomycin to peptidoglycan
glycosyltransferases and implications for antibiotic design. ACS Chemical Biology. [IF=0.963, Cited=43, 18642800].
Kahne D, Leimkuhler C, Lu W, Walsh C (2005) Glycopeptide and lipoglycopeptide antibiotics. Chemical Reviews. [IF=11.712,
Cited=296, 15700951].
Oberthür M, Losey HC, Anderson JW, ..., Kahne D (2002) The structural basis for induction of VanB resistance. Journal of
the American Chemical Society. [IF=2.573, Cited=33, 12149006].
Leimkuhler C, Chen L, Barrett D, ..., Kahne D (2005) Differential inhibition of Staphylococcus aureus PBP2 by
glycopeptide antibiotics. Journal of the American Chemical Society. [IF=2.573, Cited=26, 15755121].
Sakurai K, Chung HS, Kahne D (2004) Use of a retroinverso p53 peptide as an inhibitor of MDM2. Journal of the American
Chemical Society. [IF=2.573, Cited=33, 15600307].
Lee HY, Chung HS, Hang C, ..., Walker S (2004) Reconstitution and characterization of a new desosaminyl transferase,
EryCIII, from the erythromycin biosynthetic pathway. Journal of the American Chemical Society. [IF=2.573, Cited=12, 15303858].
Oberthür M, Leimkuhler C, Kruger RG, ..., Kahne D (2005) A systematic investigation of the synthetic utility of
glycopeptide glycosyltransferases. Journal of the American Chemical Society. [IF=2.573, Cited=41, 16045364].
Yuan Y, Chung HS, Leimkuhler C, ..., Walker S (2005) In vitro reconstitution of EryCIII activity for the preparation of
unnatural macrolides. Journal of the American Chemical Society. [IF=2.573, Cited=34, 16218575].
Sakurai K, Schubert C, Kahne D (2006) Crystallographic analysis of an 8-mer p53 peptide analogue complexed with MDM2.
Journal of the American Chemical Society. [IF=2.573, Cited=23, 16925398].
Adachi M, Zhang Y, Leimkuhler C, ..., Kahne D (2006) Degradation and reconstruction of moenomycin A and derivatives:
dissecting the function of the isoprenoid chain. Journal of the American Chemical Society. [IF=2.573, Cited=24, 17061868].
Taylor JG, Li X, Oberthür M, ..., Kahne D (2006) The total synthesis of moenomycin A. Journal of the American Chemical
Society. [IF=2.573, Cited=38, 17117848].
Zhang Y, Fechter EJ, Wang TSA, ..., Kahne D (2007) Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan
glycosyltransferases. Journal of the American Chemical Society. [IF=2.573, Cited=45, 17323951].
Leimkuhler C, Fridman M, Lupoli T, ..., Kahne D (2007) Characterization of rhodosaminyl transfer by the AknS/AknT
glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A. Journal of the American
Chemical Society. [IF=2.573, Cited=16, 17685523].
Howard-Jones AR, Kruger RG, Lu W, ..., Walsh CT (2007) Kinetic analysis of teicoplanin glycosyltransferases and
acyltransferase reveal ordered tailoring of aglycone scaffold to reconstitute mature teicoplanin. Journal of the
American Chemical Society. [IF=2.573, Cited=17, 17661468].
Perlstein DL, Zhang Y, Wang TS, ..., Walker S (2007) The direction of glycan chain elongation by peptidoglycan
glycosyltransferases. Journal of the American Chemical Society. [IF=2.573, Cited=43, 17914829].
Zhang W, Bolla ML, Kahne D, ..., Walsh CT (2010) A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation
and incorporation in natural product biosynthesis. Journal of the American Chemical Society. [IF=2.573, Cited=32, 20394362].
Zhang W, Ntai I, Bolla ML, ..., Walsh CT (2011) Nine enzymes are required for assembly of the pacidamycin group of
peptidyl nucleoside antibiotics. Journal of the American Chemical Society. [IF=2.573, Cited=38, 21417270].
Wang TSA, Lupoli TJ, Sumida Y, ..., Walker S (2011) Primer preactivation of peptidoglycan polymerases. Journal of the
American Chemical Society. [IF=2.573, Cited=21, 21568328].
Lupoli TJ, Tsukamoto H, Doud EH, ..., Kahne D (2011) Transpeptidase-mediated incorporation of D-amino acids into
bacterial peptidoglycan. Journal of the American Chemical Society. [IF=2.573, Cited=73, 21682301].
Oman TJ, Lupoli TJ, Wang TSA, ..., van der Donk WA (2011) Haloduracin α binds the peptidoglycan precursor lipid II with
2:1 stoichiometry. Journal of the American Chemical Society. [IF=2.573, Cited=35, 22003874].
Lebar MD, Lupoli TJ, Tsukamoto H, ..., Kahne D (2013) Forming cross-linked peptidoglycan from synthetic gram-negative
Lipid II. Journal of the American Chemical Society. [IF=2.573, Cited=36, 23480167].
Gampe CM, Tsukamoto H, Doud EH, ..., Kahne D (2013) Tuning the moenomycin pharmacophore to enable discovery of bacterial
cell wall synthesis inhibitors. Journal of the American Chemical Society. [IF=2.573, Cited=28, 23448584].
Lupoli TJ, Lebar MD, Markovski M, ..., Walker S (2013) Lipoprotein activators stimulate Escherichia coli penicillin-
binding proteins by different mechanisms. Journal of the American Chemical Society. [IF=2.573, Cited=46, 24341982].
Lebar MD, May JM, Meeske AJ, ..., Kahne D (2014) Reconstitution of peptidoglycan cross-linking leads to improved
fluorescent probes of cell wall synthesis. Journal of the American Chemical Society. [IF=2.573, Cited=58, 25036369].
Qiao Y, Lebar MD, Schirner K, ..., Walker S (2014) Detection of lipid-linked peptidoglycan precursors by exploiting an
unexpected transpeptidase reaction. Journal of the American Chemical Society. [IF=2.573, Cited=61, 25291014].
Hu Y, Al-Mestarihi A, Grimes CL, ..., Bachmann BO (2008) A unifying nitrososynthase involved in nitrosugar biosynthesis.
Journal of the American Chemical Society. [IF=2.573, Cited=18, 18983146].
Wang TSA, Manning SA, Walker S, Kahne D (2008) Isolated peptidoglycan glycosyltransferases from different organisms
produce different glycan chain lengths. Journal of the American Chemical Society. [IF=2.573, Cited=33, 18834124].
Tanikawa T, Fridman M, Zhu W, ..., Clemons PA (2009) Using biological performance similarity to inform disaccharide
library design. Journal of the American Chemical Society. [IF=2.573, Cited=11, 19298063].
Lupoli TJ, Taniguchi T, Wang TS, ..., Kahne D (2009) Studying a cell division amidase using defined peptidoglycan
substrates. Journal of the American Chemical Society. [IF=2.573, Cited=17, 19957935].
Perlstein DL, Wang TSA, Doud EH, ..., Walker S (2010) The role of the substrate lipid in processive glycan
polymerization by the peptidoglycan glycosyltransferases. Journal of the American Chemical Society. [IF=2.573,
Cited=33, 20017480].
Gronenberg LS, Kahne D (2010) Development of an activity assay for discovery of inhibitors of lipopolysaccharide
transport. Journal of the American Chemical Society. [IF=2.573, Cited=22, 20136079].
Baidin V, Owens TW, Lazarus MB, Kahne D (2021) Simple Secondary Amines Inhibit Growth of Gram-Negative Bacteria through
Highly Selective Binding to Phenylalanyl-tRNA Synthetase. Journal of the American Chemical Society. [IF=2.573, Cited=4, 33411531].
Lee W, Schaefer K, Qiao Y, ..., Walker S (2015) The Mechanism of Action of Lysobactin. Journal of the American Chemical
Society. [IF=2.573, Cited=31, 26683668].
Srisuknimit V, Qiao Y, Schaefer K, ..., Walker S (2017) Peptidoglycan Cross-Linking Preferences of Staphylococcus aureus
Penicillin-Binding Proteins Have Implications for Treating MRSA Infections. Journal of the American Chemical Society.
[IF=2.573, Cited=24, 28691491].
May JM, Owens TW, Mandler MD, ..., Kahne D (2017) The Antibiotic Novobiocin Binds and Activates the ATPase That Powers
Lipopolysaccharide Transport. Journal of the American Chemical Society. [IF=2.573, Cited=38, 29135241].
Welsh MA, Taguchi A, Schaefer K, ..., Walker S (2017) Identification of a Functionally Unique Family of Penicillin-
Binding Proteins. Journal of the American Chemical Society. [IF=2.573, Cited=39, 29182854].
Schaefer K, Owens TW, Kahne D, Walker S (2018) Substrate Preferences Establish the Order of Cell Wall Assembly in
Staphylococcus aureus. Journal of the American Chemical Society. [IF=2.573, Cited=16, 29402087].
Rubino FA, Kumar S, Ruiz N, ..., Kahne D (2018) Membrane Potential Is Required for MurJ Function. Journal of the
American Chemical Society. [IF=2.573, Cited=26, 29558128].
Mandler MD, Baidin V, Lee J, ..., Kahne D (2018) Novobiocin Enhances Polymyxin Activity by Stimulating
Lipopolysaccharide Transport. Journal of the American Chemical Society. [IF=2.573, Cited=31, 29746111].
Xie R, Taylor RJ, Kahne D (2018) Outer Membrane Translocon Communicates with Inner Membrane ATPase To Stop
Lipopolysaccharide Transport. Journal of the American Chemical Society. [IF=2.573, Cited=15, 30253645].
Welsh MA, Schaefer K, Taguchi A, ..., Walker S (2019) Direction of Chain Growth and Substrate Preferences of Shape,
Elongation, Division, and Sporulation-Family Peptidoglycan Glycosyltransferases. Journal of the American Chemical
Society. [IF=2.573, Cited=16, 31386359].
Rubino FA, Mollo A, Kumar S, ..., Kahne D (2020) Detection of Transport Intermediates in the Peptidoglycan Flippase MurJ
Identifies Residues Essential for Conformational Cycling. Journal of the American Chemical Society. [IF=2.573,
Cited=13, 32129990].
Meeske AJ, Riley EP, Robins WP, ..., Rudner DZ (2016) SEDS proteins are a widespread family of bacterial cell wall
polymerases. Nature. [IF=11.591, Cited=279, 27525505].
Sjodt M, Brock K, Dobihal G, ..., Kruse AC (2018) Structure of the peptidoglycan polymerase RodA resolved by
evolutionary coupling analysis. Nature. [IF=11.591, Cited=61, 29590088].
Schaefer K, Matano LM, Qiao Y, ..., Walker S (2017) In vitro reconstitution demonstrates the cell wall ligase activity
of LCP proteins. Nature Chemical Biology. [IF=2.623, Cited=42, 28166208].
Qiao Y, Srisuknimit V, Rubino F, ..., Kahne D (2017) Lipid II overproduction allows direct assay of transpeptidase
inhibition by β-lactams. Nature Chemical Biology. [IF=2.623, Cited=66, 28553948].
Okuda S, Sherman DJ, Silhavy TJ, ..., Kahne D (2016) Lipopolysaccharide transport and assembly at the outer membrane:
the PEZ model. Nature Reviews Microbiology. [IF=6.979, Cited=181, 27026255].
Taguchi A, Welsh MA, Marmont LS, ..., Walker S (2019) FtsW is a peptidoglycan polymerase that is functional only in
complex with its cognate penicillin-binding protein. Nature Microbiology. [IF=4.448, Cited=145, 30692671].
Do T, Schaefer K, Santiago AG, ..., Walker S (2020) Staphylococcus aureus cell growth and division are regulated by an
amidase that trims peptides from uncrosslinked peptidoglycan. Nature Microbiology. [IF=4.448, Cited=28, 31932712].
Schaefer K, Owens TW, Page JE, ..., Walker S (2020) Structure and reconstitution of a hydrolase complex that may release
peptidoglycan from the membrane after polymerization. Nature Microbiology. [IF=4.448, Cited=16, 33168989].
Sjodt M, Rohs PDA, Gilman MSA, ..., Kruse AC (2020) Structural coordination of polymerization and crosslinking by a
SEDS-bPBP peptidoglycan synthase complex. Nature Microbiology. [IF=4.448, Cited=63, 32152588].
Owens TW, Taylor RJ, Pahil KS, ..., Kahne D (2019) Structural basis of unidirectional export of lipopolysaccharide to
the cell surface. Nature. [IF=11.591, Cited=76, 30894747].
Tomasek D, Rawson S, Lee J, ..., Kahne D (2020) Structure of a nascent membrane protein as it folds on the BAM complex.
Nature. [IF=11.591, Cited=66, 32528179].
Törk L, Moffatt CB, Bernhardt TG, ..., Kahne D (2023) Single-molecule dynamics show a transient lipopolysaccharide
transport bridge. Nature. [IF=11.591, Cited=1, 37938784].
Pahil KS, Gilman MSA, Baidin V, ..., Kahne D (2024) A new antibiotic traps lipopolysaccharide in its intermembrane
transporter. Nature. [IF=11.591, Cited=9, 38172635].
Zampaloni C, Mattei P, Bleicher K, ..., Bradley KA (2024) A novel antibiotic class targeting the lipopolysaccharide
transporter. Nature. [IF=11.591, Cited=16, 38172634].
Pahil KS, Gilman MSA, Baidin V, ..., Kahne D (2024) Author Correction: A new antibiotic traps lipopolysaccharide in its
intermembrane transporter. Nature. [IF=11.591, Cited=0, 38200318].
Zampaloni C, Mattei P, Bleicher K, ..., Bradley KA (2024) Author Correction: A novel antibiotic class targeting the
lipopolysaccharide transporter. Nature. [IF=11.591, Cited=0, 38992182].
Pahil KS, Gilman MSA, Baidin V, ..., Kahne D (2024) Author Correction: A new antibiotic traps lipopolysaccharide in its
intermembrane transporter. Nature. [IF=11.591, Cited=0, 38992181].
Lu W, Oberthür M, Leimkuhler C, ..., Walsh CT (2004) Characterization of a regiospecific epivancosaminyl transferase
GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=26, 15070728].
Wu T, McCandlish AC, Gronenberg LS, ..., Kahne D (2006) Identification of a protein complex that assembles
lipopolysaccharide in the outer membrane of Escherichia coli. Proceedings of the National Academy of Sciences of the
United States of America. [IF=2.765, Cited=244, 16861298].
Yuan Y, Barrett D, Zhang Y, ..., Walker S (2007) Crystal structure of a peptidoglycan glycosyltransferase suggests a
model for processive glycan chain synthesis. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=87, 17360321].
Sklar JG, Wu T, Gronenberg LS, ..., Silhavy TJ (2007) Lipoprotein SmpA is a component of the YaeT complex that assembles
outer membrane proteins in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=204, 17404237].
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ (2008) Identification of two inner-membrane proteins required for the
transport of lipopolysaccharide to the outer membrane of Escherichia coli. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=174, 18375759].
Chung HS, Yao Z, Goehring NW, ..., Kahne D (2009) Rapid beta-lactam-induced lysis requires successful assembly of the
cell division machinery. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=73, 19995973].
Chng SS, Ruiz N, Chimalakonda G, ..., Kahne D (2010) Characterization of the two-protein complex in Escherichia coli
responsible for lipopolysaccharide assembly at the outer membrane. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=136, 20203010].
Ruiz N, Chng SS, Hiniker A, ..., Silhavy TJ (2010) Nonconsecutive disulfide bond formation in an essential integral
outer membrane protein. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=75, 20566849].
Freinkman E, Chng SS, Kahne D (2011) The complex that inserts lipopolysaccharide into the bacterial outer membrane forms
a two-protein plug-and-barrel. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=115, 21257904].
Chimalakonda G, Ruiz N, Chng SS, ..., Silhavy TJ (2011) Lipoprotein LptE is required for the assembly of LptD by the
beta-barrel assembly machine in the outer membrane of Escherichia coli. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=90, 21257909].
Ricci DP, Hagan CL, Kahne D, Silhavy TJ (2012) Activation of the Escherichia coli β-barrel assembly machine (Bam) is
required for essential components to interact properly with substrate. Proceedings of the National Academy of Sciences
of the United States of America. [IF=2.765, Cited=66, 22331884].
Yao Z, Davis RM, Kishony R, ..., Ruiz N (2012) Regulation of cell size in response to nutrient availability by fatty
acid biosynthesis in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=108, 22908292].
Sherman DJ, Lazarus MB, Murphy L, ..., Kahne D (2014) Decoupling catalytic activity from biological function of the
ATPase that powers lipopolysaccharide transport. Proceedings of the National Academy of Sciences of the United States of
America. [IF=2.765, Cited=58, 24639492].
Malojčić G, Andres D, Grabowicz M, ..., Kahne D (2014) LptE binds to and alters the physical state of LPS to catalyze
its assembly at the cell surface. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=54, 24938785].
Hagan CL, Wzorek JS, Kahne D (2015) Inhibition of the β-barrel assembly machine by a peptide that binds BamD.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=69, 25646443].
Markovski M, Bohrhunter JL, Lupoli TJ, ..., Bernhardt TG (2016) Cofactor bypass variants reveal a conformational control
mechanism governing cell wall polymerase activity. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=25, 27071112].
Lee J, Xue M, Wzorek JS, ..., Kahne D (2016) Characterization of a stalled complex on the β-barrel assembly machine.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=57, 27439868].
Wzorek JS, Lee J, Tomasek D, ..., Kahne D (2017) Membrane integration of an essential β-barrel protein prerequires
burial of an extracellular loop. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=23, 28223520].
Lee J, Sutterlin HA, Wzorek JS, ..., Kahne D (2018) Substrate binding to BamD triggers a conformational change in BamA
to control membrane insertion. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=34, 29463713].
Zhang G, Baidin V, Pahil KS, ..., Kahne D (2018) Cell-based screen for discovering lipopolysaccharide biogenesis
inhibitors. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=49, 29735709].
Horan N, Yan L, Isobe H, ..., Kahne D (1999) Nonstatistical binding of a protein to clustered carbohydrates. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=86, 10518527].
May JM, Sherman DJ, Simpson BW, ..., Kahne D (2015) Lipopolysaccharide transport to the cell surface: periplasmic
transport and assembly into the outer membrane. Philosophical Transactions of the Royal Society B: Biological Sciences.
[IF=1.629, Cited=37, 26370939].
Simpson BW, May JM, Sherman DJ, ..., Ruiz N (2015) Lipopolysaccharide transport to the cell surface: biosynthesis and
extraction from the inner membrane. Philosophical Transactions of the Royal Society B: Biological Sciences. [IF=1.629,
Cited=42, 26370941].
Bertani BR, Taylor RJ, Nagy E, ..., Ruiz N (2018) A cluster of residues in the lipopolysaccharide exporter that selects
substrate variants for transport to the outer membrane. Molecular Microbiology. [IF=1.094, Cited=14, 29995974].
Kim S, Malinverni JC, Sliz P, ..., Kahne D (2007) Structure and function of an essential component of the outer membrane
protein assembly machine. Science. [IF=7.729, Cited=248, 17702946].
Hagan CL, Kim S, Kahne D (2010) Reconstitution of outer membrane protein assembly from purified components. Science.
[IF=7.729, Cited=177, 20378773].
Chng SS, Xue M, Garner RA, ..., Kahne D (2012) Disulfide rearrangement triggered by translocon assembly controls
lipopolysaccharide export. Science. [IF=7.729, Cited=62, 22936569].
Okuda S, Freinkman E, Kahne D (2012) Cytoplasmic ATP hydrolysis powers transport of lipopolysaccharide across the
periplasm in E. coli. Science. [IF=7.729, Cited=122, 23138981].
Sham LT, Butler EK, Lebar MD, ..., Ruiz N (2014) Bacterial cell wall. MurJ is the flippase of lipid-linked precursors
for peptidoglycan biogenesis. Science. [IF=7.729, Cited=184, 25013077].
Sherman DJ, Xie R, Taylor RJ, ..., Kahne D (2018) Lipopolysaccharide is transported to the cell surface by a membrane-
to-membrane protein bridge. Science. [IF=7.729, Cited=73, 29449493].
Buss JA, Baidin V, Welsh MA, ..., Bernhardt TG (2018) Pathway-Directed Screen for Inhibitors of the Bacterial Cell
Elongation Machinery. Antimicrobial Agents and Chemotherapy. [IF=1.175, Cited=13, 30323039].
Nagy E, Losick R, Kahne D (2019) Robust Suppression of Lipopolysaccharide Deficiency in Acinetobacter baumannii by
Growth in Minimal Medium. Journal of Bacteriology. [IF=0.898, Cited=13, 31451545].
Hart EM, O'Connell A, Tang K, ..., Silhavy TJ (2019) Fine-Tuning of σ^E Activation Suppresses Multiple
Assembly-Defective Mutations in Escherichia coli. Journal of Bacteriology. [IF=0.898, Cited=4, 30858299].
Barrett D, Leimkuhler C, Chen L, ..., Walker S (2005) Kinetic characterization of the glycosyltransferase module of
Staphylococcus aureus PBP2. Journal of Bacteriology. [IF=0.898, Cited=32, 15743972].
Simpson BW, Owens TW, Orabella MJ, ..., Ruiz N (2016) Identification of Residues in the Lipopolysaccharide ABC
Transporter That Coordinate ATPase Activity with Extractor Function. mBio. [IF=1.357, Cited=25, 27795402].
Simpson BW, Pahil KS, Owens TW, ..., Ruiz N (2019) Combining Mutations That Inhibit Two Distinct Steps of the ATP
Hydrolysis Cycle Restores Wild-Type Function in the Lipopolysaccharide Transporter and Shows that ATP Binding Triggers
Transport. mBio. [IF=1.357, Cited=13, 31431556].
Kumar S, Mollo A, Rubino FA, ..., Ruiz N (2023) Chloride Ions Are Required for Thermosipho africanus MurJ Function.
mBio. [IF=1.357, Cited=1, 36752629].
Falchi FA, Taylor RJ, Rowe SJ, ..., Sperandeo P (2022) Suppressor Mutations in LptF Bypass Essentiality of LptC by
Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide. mBio. [IF=1.357, Cited=2, 36541759].
Hagan CL, Silhavy TJ, Kahne D (2011) β-Barrel membrane protein assembly by the Bam complex. Annual Review of
Biochemistry. [IF=5.273, Cited=205, 21370981].
Konovalova A, Kahne D, Silhavy TJ (2017) Outer Membrane Biogenesis. Annual Review of Microbiology. [IF=3.167,
Cited=142, 28886680].
Rohs PDA, Buss J, Sim SI, ..., Bernhardt TG (2018) A central role for PBP2 in the activation of peptidoglycan
polymerization by the bacterial cell elongation machinery. PLoS Genetics. [IF=1.236, Cited=76, 30335755].
Grabowicz M, Andres D, Lebar MD, ..., Silhavy TJ (2014) A mutant Escherichia coli that attaches peptidoglycan to
lipopolysaccharide and displays cell wall on its surface. eLife. [IF=1.743, Cited=15, 25551294].
Lee J, Tomasek D, Santos TM, ..., Kahne D (2019) Formation of a β-barrel membrane protein is catalyzed by the interior
surface of the assembly machine protein BamA. eLife. [IF=1.743, Cited=36, 31724945].

Publication with MISSING institution:

Basu A, Kahne D (2003) Overcoming degeneracy in carbohydrate recognition. Angewandte Chemie - International Edition.
[IF=2.456, Cited=3, 12800171].
Howorka S, Nam J, Bayley H, Kahne D (2004) Stochastic detection of monovalent and bivalent protein-ligand interactions.
Angewandte Chemie - International Edition. [IF=2.456, Cited=40, 14767954].
Freel Meyers CL, Oberthür M, Xu H, ..., Walsh CT (2004) Characterization of NovP and NovN: completion of novobiocin
biosynthesis by sequential tailoring of the noviosyl ring. Angewandte Chemie - International Edition. [IF=2.456,
Cited=24, 14694473].
Kagan E, Ragupathi G, Yi SS, ..., Livingston PO (2004) Comparison of antigen constructs and carrier molecules for
augmenting the immunogenicity of the monosaccharide epithelial cancer antigen Tn. Cancer Immunology, Immunotherapy.
[IF=1.065, Cited=60, 15625606].
Ngundi MM, Taitt CR, McMurry SA, ..., Ligler FS (2005) Detection of bacterial toxins with monosaccharide arrays.
Biosensors and Bioelectronics. [IF=1.844, Cited=27, 15946840].
Sherman DJ, Okuda S, Denny WA, Kahne D (2013) Validation of inhibitors of an ABC transporter required to transport
lipopolysaccharide to the cell surface in Escherichia coli. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=21, 23665139].
Tsukamoto H, Kahne D (2011) N-methylimidazolium chloride-catalyzed pyrophosphate formation: application to the synthesis
of Lipid I and NDP-sugar donors. Bioorganic and Medicinal Chemistry Letters. [IF=0.704, Cited=15, 21592792].
Ruiz N, Falcone B, Kahne D, Silhavy TJ (2005) Chemical conditionality: a genetic strategy to probe organelle assembly.
Cell. [IF=8.479, Cited=218, 15851036].
Wu T, Malinverni J, Ruiz N, ..., Kahne D (2005) Identification of a multicomponent complex required for outer membrane
biogenesis in Escherichia coli. Cell. [IF=8.479, Cited=479, 15851030].
Paradis-Bleau C, Markovski M, Uehara T, ..., Bernhardt TG (2010) Lipoprotein cofactors located in the outer membrane
activate bacterial cell wall polymerases. Cell. [IF=8.479, Cited=209, 21183074].
Kruger RG, Lu W, Oberthür M, ..., Walsh CT (2005) Tailoring of glycopeptide scaffolds by the acyltransferases from the
teicoplanin and A-40,926 biosynthetic operons. None. [IF=None, Cited=24, 15664522].
Lu W, Leimkuhler C, Gatto GJ, ..., Walsh CT (2005) AknT is an activating protein for the glycosyltransferase AknS in
L-aminodeoxysugar transfer to the aglycone of aclacinomycin A. None. [IF=None, Cited=43, 15911373].
Zhang G, Meredith TC, Kahne D (2013) On the essentiality of lipopolysaccharide to Gram-negative bacteria. Current
Opinion in Microbiology. [IF=1.52, Cited=157, 24148302].
Yao Z, Kahne D, Kishony R (2012) Distinct single-cell morphological dynamics under beta-lactam antibiotics. Molecular
Cell. [IF=2.773, Cited=109, 23103254].
Gampe CM, Tsukamoto H, Wang TSA, ..., Kahne D (2011) Modular synthesis of diphospholipid oligosaccharide fragments of
the bacterial cell wall and their use to study the mechanism of moenomycin and other antibiotics. Tetrahedron.
[IF=0.579, Cited=21, 22505780].
Sakurai K, Kahne D (2010) Design and Synthesis of Functionalized Trisaccharides as p53-Peptide Mimics. Tetrahedron
Letters. [IF=0.515, Cited=3, 20676223].
Silva DJ, Kraml CM, Kahne D (1994) Use of triethylene glycol to mimic oligosaccharides: design and synthesis of a ligand
based on chromomycin A3. Bioorganic and Medicinal Chemistry. [IF=0.86, Cited=2, 7757421].
Losey HC, Jiang J, Biggins JB, ..., Walsh CT (2002) Incorporation of glucose analogs by GtfE and GtfD from the
vancomycin biosynthetic pathway to generate variant glycopeptides. None. [IF=None, Cited=82, 12498883].
Silva DJ, Goodnow R, Kahne D (1993) The sugars in chromomycin A3 stabilize the Mg(2+)-dimer complex. Biochemistry.
[IF=0.753, Cited=15, 8422355].
Ruiz N, Kahne D, Silhavy TJ (2006) Advances in understanding bacterial outer-membrane biogenesis. Nature Reviews
Microbiology. [IF=6.979, Cited=281, 16357861].
Ruiz N, Kahne D, Silhavy TJ (2009) Transport of lipopolysaccharide across the cell envelope: the long road of discovery.
Nature Reviews Microbiology. [IF=6.979, Cited=150, 19633680].
Barrett D, Wang TSA, Yuan Y, ..., Walker S (2007) Analysis of glycan polymers produced by peptidoglycan
glycosyltransferases. Journal of Biological Chemistry. [IF=1.122, Cited=54, 17704540].
Silhavy TJ, Kahne D, Walker S (2010) The bacterial cell envelope. Cold Spring Harbor perspectives in biology. [IF=1.926,
Cited=1000, 20452953].
Sklar JG, Wu T, Kahne D, Silhavy TJ (2007) Defining the roles of the periplasmic chaperones SurA, Skp, and DegP in
Escherichia coli. Genes and Development. [IF=1.985, Cited=297, 17908933].
Shigeta R, Forest K, Yan L, ..., Schutt CE (1994) Isomorphous binding of mercury-substituted thiosaccharides to
pertussis toxin crystals yields crystallographic phases. None. [IF=None, Cited=2, 15299478].
Malinverni JC, Werner J, Kim S, ..., Silhavy TJ (2006) YfiO stabilizes the YaeT complex and is essential for outer
membrane protein assembly in Escherichia coli. Molecular Microbiology. [IF=1.094, Cited=212, 16824102].
Leiman SA, May JM, Lebar MD, ..., Losick R (2013) D-amino acids indirectly inhibit biofilm formation in Bacillus
subtilis by interfering with protein synthesis. Journal of Bacteriology. [IF=0.898, Cited=95, 24097941].
Villa R, Martorana AM, Okuda S, ..., Polissi A (2013) The Escherichia coli Lpt transenvelope protein complex for
lipopolysaccharide export is assembled via conserved structurally homologous domains. Journal of Bacteriology.
[IF=0.898, Cited=71, 23292770].
Pine MB, Kahne D, Jaski B, ..., Abelmann WH (1980) Sodium permeability and myocardial resistance to cell swelling during
metabolic blockade. None. [IF=None, Cited=9, 7396015].

Kahne, Dan

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Publication with MISMATCHING institution:

Publication with MISSING institution: