Jinek, Martin
Publication with MATCHING institution:
- Brandmann T, Jinek M (2015) Crystal structure of the C-terminal 2',5'-phosphodiesterase domain of group A rotavirus
protein VP3. Proteins: Structure, Function and Bioinformatics. [IF=0.897, Cited=10, 25758703].
- Swarts DC, Jinek M (2018) Cas9 versus Cas12a/Cpf1: Structure-function comparisons and implications for genome editing.
Wiley interdisciplinary reviews. RNA. [IF=1.585, Cited=89, 29790280].
- Dumeau CE, Monfort A, Kissling L, ..., Wutz A (2019) Introducing gene deletions by mouse zygote electroporation of
Cas12a/Cpf1. Transgenic Research. [IF=0.672, Cited=11, 31482512].
- Anders C, Jinek M (2014) In vitro enzymology of Cas9. None. [IF=None, Cited=58, 25398333].
- Anders C, Niewoehner O, Jinek M (2015) In Vitro Reconstitution and Crystallization of Cas9 Endonuclease Bound to a Guide
RNA and a DNA Target. None. [IF=None, Cited=13, 26068752].
- Kissling L, Monfort A, Swarts DC, ..., Jinek M (2019) Preparation and electroporation of Cas12a/Cpf1-guide RNA complexes
for introducing large gene deletions in mouse embryonic stem cells. None. [IF=None, Cited=12, 30691645].
- Pacesa M, Lin CH, Cléry A, ..., Jinek M (2022) Structural basis for Cas9 off-target activity. Cell. [IF=8.479,
Cited=39, 36306733].
- Schmitz M, Querques I, Oberli S, ..., Jinek M (2022) Structural basis for the assembly of the type V CRISPR-associated
transposon complex. Cell. [IF=8.479, Cited=25, 36435179].
- Pacesa M, Pelea O, Jinek M (2024) Past, present, and future of CRISPR genome editing technologies. Cell. [IF=8.479,
Cited=3, 38428389].
- Niewoehner O, Jinek M (2017) Specialized Weaponry: How a Type III-A CRISPR-Cas System Excels at Combating Phages. None.
[IF=None, Cited=3, 28910631].
- Anders C, Bargsten K, Jinek M (2016) Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided
Endonuclease Cas9. Molecular Cell. [IF=2.773, Cited=97, 26990992].
- Swarts DC, van der Oost J, Jinek M (2017) Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by
CRISPR-Cas12a. Molecular Cell. [IF=2.773, Cited=228, 28431230].
- Swarts DC, Jinek M (2019) Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a. Molecular
Cell. [IF=2.773, Cited=142, 30639240].
- Asanović I, Strandback E, Kroupova A, ..., Martinez J (2021) The oxidoreductase PYROXD1 uses NAD(P)+ as an
antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response. Molecular Cell.
[IF=2.773, Cited=12, 33930333].
- Donohoue PD, Pacesa M, Lau E, ..., Cameron P (2021) Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides
mitigates off-target activity in T cells. Molecular Cell. [IF=2.773, Cited=15, 34478654].
- Wrona D, Pastukhov O, Pritchard RS, ..., Reichenbach J (2020) CRISPR-Directed Therapeutic Correction at the NCF1
Locus Is Challenged by Frequent Incidence of Chromosomal Deletions. Molecular Therapy - Methods and Clinical
Development. [IF=0.981, Cited=4, 32420407].
- Siow KM, Güngör M, Wrona D, ..., Reichenbach J (2024) Targeted knock-in of NCF1 cDNA into the NCF2 locus
leads to myeloid phenotypic correction of p47 phox -deficient chronic granulomatous disease. Molecular
Therapy - Nucleic Acids. [IF=1.318, Cited=0, 38952440].
- Garcia-Doval C, Jinek M (2017) Molecular architectures and mechanisms of Class 2 CRISPR-associated nucleases. Current
Opinion in Structural Biology. [IF=1.4, Cited=30, 29107822].
- Kumar A, Clerici M, Muckenfuss LM, ..., Jinek M (2019) Mechanistic insights into mRNA 3'-end processing. Current Opinion
in Structural Biology. [IF=1.4, Cited=56, 31499460].
- Saha A, Arantes PR, Hsu RV, ..., Palermo G (2020) Molecular Dynamics Reveals a DNA-Induced Dynamic Switch Triggering
Activation of CRISPR-Cas12a. Journal of Chemical Information and Modeling. [IF=1.379, Cited=27, 33107304].
- Palermo G, Miao Y, Walker RC, ..., McCammon JA (2016) Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA,
as Revealed by Molecular Simulations. ACS Central Science. [IF=2.363, Cited=63, 27800559].
- Makasheva K, Bryan LC, Anders C, ..., Fierz B (2021) Multiplexed Single-Molecule Experiments Reveal Nucleosome Invasion
Dynamics of the Cas9 Genome Editor. Journal of the American Chemical Society. [IF=2.573, Cited=4, 34597515].
- Sternberg SH, Redding S, Jinek M, ..., Doudna JA (2014) DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
Nature. [IF=11.591, Cited=958, 24476820].
- Anders C, Niewoehner O, Duerst A, Jinek M (2014) Structural basis of PAM-dependent target DNA recognition by the Cas9
endonuclease. Nature. [IF=11.591, Cited=654, 25079318].
- Niewoehner O, Garcia-Doval C, Rostøl JT, ..., Jinek M (2017) Type III CRISPR-Cas systems produce cyclic oligoadenylate
second messengers. Nature. [IF=11.591, Cited=216, 28722012].
- Lindsay H, Burger A, Biyong B, ..., Robinson MD (2016) CrispRVariants charts the mutation spectrum of genome engineering
experiments. Nature Biotechnology. [IF=8.861, Cited=84, 27404876].
- Garcia-Doval C, Schwede F, Berk C, ..., Jinek M (2020) Activation and self-inactivation mechanisms of the cyclic
oligoadenylate-dependent CRISPR ribonuclease Csm6. Nature Communications. [IF=3.268, Cited=48, 32221291].
- Bawankar P, Lence T, Paolantoni C, ..., Roignant JY (2021) Hakai is required for stabilization of core components of the
m6A mRNA methylation machinery. Nature Communications. [IF=3.268, Cited=56, 34145251].
- Zhao L, Koseki SRT, Silverstein RA, ..., Chatterjee P (2023) PAM-flexible genome editing with an engineered chimeric
Cas9. Nature Communications. [IF=3.268, Cited=3, 37794046].
- Weber Y, Böck D, Ivașcu A, ..., Schwank G (2024) Enhancing prime editor activity by directed protein evolution in yeast.
Nature Communications. [IF=3.268, Cited=0, 38453904].
- Bastiaanssen C, Bobadilla Ugarte P, Kim K, ..., Wu F (2024) RNA-guided RNA silencing by an Asgard archaeal Argonaute.
Nature Communications. [IF=3.268, Cited=1, 38951509].
- Reginato G, Dello Stritto MR, Wang Y, ..., Cejka P (2024) HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA
break processing. Nature Communications. [IF=3.268, Cited=0, 38987539].
- Querques I, Schmitz M, Oberli S, ..., Jinek M (2021) Target site selection and remodelling by type V CRISPR-transposon
systems. Nature. [IF=11.591, Cited=31, 34759315].
- Pacesa M, Loeff L, Querques I, ..., Jinek M (2022) R-loop formation and conformational activation mechanisms of Cas9.
Nature. [IF=11.591, Cited=32, 36002571].
- Pacesa M, Loeff L, Querques I, ..., Jinek M (2023) Publisher Correction: R-loop formation and conformational activation
mechanisms of Cas9. Nature. [IF=11.591, Cited=0, 37903882].
- Rothgangl T, Dennis MK, Lin PJC, ..., Schwank G (2021) In vivo adenine base editing of PCSK9 in macaques reduces LDL
cholesterol levels. Nature Biotechnology. [IF=8.861, Cited=137, 34012094].
- Schmidheini L, Mathis N, Marquart KF, ..., Schwank G (2023) Continuous directed evolution of a compact CjCas9 variant
with broad PAM compatibility. Nature Chemical Biology. [IF=2.623, Cited=2, 37735239].
- Clerici M, Faini M, Muckenfuss LM, ..., Jinek M (2018) Structural basis of AAUAAA polyadenylation signal recognition by
the human CPSF complex. Nature Structural and Molecular Biology. [IF=2.542, Cited=63, 29358758].
- Clerici M, Faini M, Muckenfuss LM, ..., Jinek M (2018) Author Correction: Structural basis of AAUAAA polyadenylation
signal recognition by the human CPSF complex. Nature Structural and Molecular Biology. [IF=2.542, Cited=0, 29540792].
- Jungfer K, Sigg A, Jinek M (2024) Substrate selectivity and catalytic activation of the type III CRISPR ancillary
nuclease Can2. Nucleic Acids Research. [IF=4.663, Cited=0, 38033326].
- Finocchio G, Koopal B, Potocnik A, ..., Swarts DC (2024) Target DNA-dependent activation mechanism of the prokaryotic
immune system SPARTA. Nucleic Acids Research. [IF=4.663, Cited=3, 38224450].
- Vlot M, Houkes J, Lochs SJA, ..., Brouns SJJ (2018) Bacteriophage DNA glucosylation impairs target DNA binding by type I
and II but not by type V CRISPR-Cas effector complexes. Nucleic Acids Research. [IF=4.663, Cited=30, 29253268].
- Nishimura T, Fakim H, Brandmann T, ..., Fabian MR (2018) Human MARF1 is an endoribonuclease that interacts with the
DCP1:2 decapping complex and degrades target mRNAs. Nucleic Acids Research. [IF=4.663, Cited=14, 30364987].
- Kroupova A, Ivascu A, Reimão-Pinto MM, ..., Jinek M (2019) Structural basis for acceptor RNA substrate selectivity of
the 3' terminal uridylyl transferase Tailor. Nucleic Acids Research. [IF=4.663, Cited=8, 30462292].
- Hegge JW, Swarts DC, Chandradoss SD, ..., van der Oost J (2019) DNA-guided DNA cleavage at moderate temperatures by
Clostridium butyricum Argonaute. Nucleic Acids Research. [IF=4.663, Cited=63, 31069393].
- Olieric V, Weinert T, Finke AD, ..., Wang M (2016) Data-collection strategy for challenging native SAD phasing. Acta
Crystallographica Section D: Structural Biology. [IF=1.47, Cited=20, 26960129].
- Jinek M, Jiang F, Taylor DW, ..., Doudna JA (2014) Structures of Cas9 endonucleases reveal RNA-mediated conformational
activation. Science. [IF=7.729, Cited=573, 24505130].
- Baltimore D, Berg P, Botchan M, ..., Yamamoto KR (2015) Biotechnology. A prudent path forward for genomic engineering
and germline gene modification. Science. [IF=7.729, Cited=225, 25791083].
- Pinto PH, Kroupova A, Schleiffer A, ..., Martinez J (2020) ANGEL2 is a member of the CCR4 family of deadenylases with
2',3'-cyclic phosphatase activity. Science. [IF=7.729, Cited=13, 32732418].
- Loeff L, Adams DW, Chanez C, ..., Jinek M (2024) Molecular mechanism of plasmid elimination by the DdmDE defense system.
Science. [IF=7.729, Cited=0, 38870273].
- Niewoehner O, Jinek M (2016) Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated
protein Csm6. RNA. [IF=0.956, Cited=80, 26763118].
- Boneberg FM, Brandmann T, Kobel L, ..., Jinek M (2019) Molecular mechanism of the RNA helicase DHX37 and its activation
by UTP14A in ribosome biogenesis. RNA. [IF=0.956, Cited=22, 30910870].
- Reimão-Pinto MM, Manzenreither RA, Burkard TR, ..., Ameres SL (2016) Molecular basis for cytoplasmic RNA surveillance by
uridylation-triggered decay in Drosophila. EMBO Journal. [IF=2.114, Cited=36, 27729457].
- Brandmann T, Fakim H, Padamsi Z, ..., Jinek M (2018) Molecular architecture of LSM14 interactions involved in the
assembly of mRNA silencing complexes. EMBO Journal. [IF=2.114, Cited=35, 29510985].
- Koseki S, Hong L, Yudistyra V, ..., Chatterjee P (2023) PAM-Flexible Genome Editing with an Engineered Chimeric Cas9.
None. [IF=None, Cited=0, 36945419].
- Mohanraju P, Van Der Oost J, Jinek M, Swarts DC (2018) Heterologous Expression and Purification of CRISPR-Cas12a/Cpf1.
Bio-protocol. [IF=0.267, Cited=12, 34286046].
- Savić N, Ringnalda FC, Berk C, ..., Schwank G (2019) In vitro Generation of CRISPR-Cas9 Complexes with Covalently
Bound Repair Templates for Genome Editing in Mammalian Cells. Bio-protocol. [IF=0.267, Cited=10, 30675496].
- Zou J, Tran D, Baalbaki M, ..., Deo RC (2015) An internal promoter underlies the difference in disease severity between
N- and C-terminal truncation mutations of Titin in zebrafish. eLife. [IF=1.743, Cited=55, 26473617].
- Śledź P, Jinek M (2016) Structural insights into the molecular mechanism of the m(6)A writer complex. eLife. [IF=1.743,
Cited=262, 27627798].
- Clerici M, Faini M, Aebersold R, Jinek M (2017) Structural insights into the assembly and polyA signal recognition
mechanism of the human CPSF complex. eLife. [IF=1.743, Cited=48, 29274231].
- Savic N, Ringnalda FC, Lindsay H, ..., Schwank G (2018) Covalent linkage of the DNA repair template to the CRISPR-Cas9
nuclease enhances homology-directed repair. eLife. [IF=1.743, Cited=81, 29809142].
- Kroupova A, Ackle F, Asanović I, ..., Jinek M (2021) Molecular architecture of the human tRNA ligase complex. eLife.
[IF=1.743, Cited=15, 34854379].
- Muckenfuss LM, Migenda Herranz AC, Boneberg FM, ..., Jinek M (2022) Fip1 is a multivalent interaction scaffold for
processing factors in human mRNA 3' end biogenesis. eLife. [IF=1.743, Cited=4, 36073787].
Publication with MISMATCHING institution:
- Jinek M, Coyle SM, Doudna JA (2011) Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay.
Molecular Cell. [IF=2.773, Cited=115, 21362555].
- Palermo G, Chen JS, Ricci CG, ..., McCammon JA (2018) Key role of the REC lobe during CRISPR-Cas9 activation by
'sensing', 'regulating', and 'locking' the catalytic HNH domain. Quarterly Reviews of Biophysics. [IF=1.372, Cited=48, 30555184].
- Casalino L, Nierzwicki Ł, Jinek M, Palermo G (2020) Catalytic Mechanism of Non-Target DNA Cleavage in CRISPR-Cas9
Revealed by Ab Initio Molecular Dynamics. ACS Catalysis. [IF=2.134, Cited=36, 33520346].
- Ricci CG, Chen JS, Miao Y, ..., Palermo G (2019) Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated
Molecular Dynamics. ACS Central Science. [IF=2.363, Cited=49, 31041385].
- Weibel N, Curcio M, Schreiber A, ..., Antunes Westmann C (2024) Engineering a Novel Probiotic Toolkit in Escherichia
coli Nissle 1917 for Sensing and Mitigating Gut Inflammatory Diseases. ACS Synthetic Biology. [IF=0.96,
Cited=0, 39115381].
- Weeks AM, Coyle SM, Jinek M, ..., Chang MCY (2010) Structural and biochemical studies of a fluoroacetyl-CoA-specific
thioesterase reveal a molecular basis for fluorine selectivity. Biochemistry. [IF=0.753, Cited=23, 20836570].
- Palermo G, Ricci CG, Fernando A, ..., McCammon JA (2017) Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-
Cas9. Journal of the American Chemical Society. [IF=2.573, Cited=63, 28764328].
- Jinek M, Doudna JA (2009) A three-dimensional view of the molecular machinery of RNA interference. Nature. [IF=11.591,
Cited=411, 19158786].
- Jinek M, Fabian MR, Coyle SM, ..., Doudna JA (2010) Structural insights into the human GW182-PABC interaction in
microRNA-mediated deadenylation. Nature Structural and Molecular Biology. [IF=2.542, Cited=72, 20098421].
- Jinek M, Chen YW, Clausen H, ..., Conti E (2006) Structural insights into the Notch-modifying glycosyltransferase
Fringe. Nature Structural and Molecular Biology. [IF=2.542, Cited=21, 16964258].
- Saha A, Ahsan M, Arantes PR, ..., Palermo G (2024) An alpha-helical lid guides the target DNA toward catalysis in
CRISPR-Cas12a. Nature Communications. [IF=3.268, Cited=0, 38368461].
- Nierzwicki Ł, East KW, Binz JM, ..., Palermo G (2022) Principles of target DNA cleavage and the role of Mg2+ in the
catalysis of CRISPR-Cas9. Nature Catalysis. [IF=5.117, Cited=15, 36778082].
- Palermo G, Miao Y, Walker RC, ..., McCammon JA (2017) CRISPR-Cas9 conformational activation as elucidated from enhanced
molecular simulations. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=76, 28652374].
- Jinek M, Conti E (2006) Eukaryotic expression, purification, crystallization and preliminary X-ray analysis of murine
Manic Fringe. None. [IF=None, Cited=0, 16880554].
- Haurwitz RE, Jinek M, Wiedenheft B, ..., Doudna JA (2010) Sequence- and structure-specific RNA processing by a CRISPR
endonuclease. Science. [IF=7.729, Cited=422, 20829488].
- Jinek M, Chylinski K, Fonfara I, ..., Charpentier E (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive
bacterial immunity. Science. [IF=7.729, Cited=1000, 22745249].
- Cook A, Bono F, Jinek M, Conti E (2007) Structural biology of nucleocytoplasmic transport. Annual Review of
Biochemistry. [IF=5.273, Cited=339, 17506639].
- Burger A, Lindsay H, Felker A, ..., Mosimann C (2016) Maximizing mutagenesis with solubilized CRISPR-Cas9
ribonucleoprotein complexes. Development (Cambridge). [IF=1.291, Cited=162, 27130213].
- Jinek M, Eulalio A, Lingel A, ..., Izaurralde E (2008) The C-terminal region of Ge-1 presents conserved structural
features required for P-body localization. RNA. [IF=0.956, Cited=27, 18755833].
- Jinek M, East A, Cheng A, ..., Doudna J (2013) RNA-programmed genome editing in human cells. eLife. [IF=1.743,
Cited=1000, 23386978].
Publication with MISSING institution:
- Leung AKW, Kambach C, Kondo Y, ..., Nagai K (2010) Use of RNA tertiary interaction modules for the crystallisation of
the spliceosomal snRNP core domain. Journal of Molecular Biology. [IF=1.281, Cited=10, 20643141].
- Fabian MR, Mathonnet G, Sundermeier T, ..., Sonenberg N (2009) Mammalian miRNA RISC recruits CAF1 and PABP to affect
PABP-dependent deadenylation. Molecular Cell. [IF=2.773, Cited=253, 19716330].
- Wiedenheft B, Zhou K, Jinek M, ..., Doudna JA (2009) Structural basis for DNase activity of a conserved protein
implicated in CRISPR-mediated genome defense. Structure. [IF=1.155, Cited=146, 19523907].
- Cook AG, Fukuhara N, Jinek M, Conti E (2009) Structures of the tRNA export factor in the nuclear and cytosolic states.
Nature. [IF=11.591, Cited=83, 19680239].
- Sashital DG, Jinek M, Doudna JA (2011) An RNA-induced conformational change required for CRISPR RNA cleavage by the
endoribonuclease Cse3. Nature Structural and Molecular Biology. [IF=2.542, Cited=117, 21572442].
- Kassube SA, Jinek M, Fang J, ..., Nogales E (2013) Structural mimicry in transcription regulation of human RNA
polymerase II by the DNA helicase RECQL5. Nature Structural and Molecular Biology. [IF=2.542, Cited=24, 23748380].
- Niewoehner O, Jinek M, Doudna JA (2013) Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Nucleic Acids Research. [IF=4.663, Cited=48, 24150936].
- Boneberg FM, Brandmann T, Kobel L, ..., Jinek M (2019) Corrigendum: Molecular mechanism of the RNA helicase DHX37 and
its activation by UTP14A in ribosome biogenesis. RNA. [IF=0.956, Cited=0, 31619564].