Doudna, Jennifer A

Publication with MATCHING institution:

Doudna JA (2015) Genomic engineering and the future of medicine. None. [IF=None, Cited=16, 25710652].
Kan MJ, Doudna JA (2022) Treatment of Genetic Diseases With CRISPR Genome Editing. None. [IF=None, Cited=7, 36098733].
Knight SC, Tjian R, Doudna JA (2018) Genomes in Focus: Development and Applications of CRISPR-Cas9 Imaging Technologies.
Angewandte Chemie - International Edition. [IF=2.456, Cited=34, 29080263].
Floor SN, Barkovich KJ, Condon KJ, ..., Doudna JA (2015) Analog sensitive chemical inhibition of the DEAD-box protein
DDX3. Protein Science. [IF=1.97, Cited=6, 26650549].
Noureddine A, Maestas-Olguin A, Saada EA, ..., Serda RE (2020) Engineering of monosized lipid-coated mesoporous silica
nanoparticles for CRISPR delivery. None. [IF=None, Cited=29, 32702530].
Noureddine A, Maestas-Olguin A, Saada EA, ..., Serda RE (2020) Corrigendum to "Engineering of monosized lipid-coated
mesoporous silica nanoparticles for CRISPR delivery" Acta Biomaterialia (2020), 114, 358-368. None. [IF=None, Cited=1, 33309186].
Mancini A, Xavier-Magalhães A, Woods WS, ..., Costello JF (2018) Disruption of the β1L Isoform of GABP Reverses
Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. Cancer Cell. [IF=5.274, Cited=75, 30205050].
MacRae IJ, Doudna JA (2005) Ro's role in RNA reconnaissance. Cell. [IF=8.479, Cited=5, 15907458].
Kranzusch PJ, Lee ASY, Wilson SC, ..., Doudna JA (2014) Structure-guided reprogramming of human cGAS dinucleotide
linkage specificity. Cell. [IF=8.479, Cited=72, 25131990].
Redding S, Sternberg SH, Marshall M, ..., Greene EC (2015) Surveillance and Processing of Foreign DNA by the Escherichia
coli CRISPR-Cas System. Cell. [IF=8.479, Cited=115, 26522594].
Wright AV, Nuñez JK, Doudna JA (2016) Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome
Engineering. Cell. [IF=8.479, Cited=537, 26771484].
Nelles DA, Fang MY, O'Connell MR, ..., Yeo GW (2016) Programmable RNA Tracking in Live Cells with CRISPR/Cas9. Cell.
[IF=8.479, Cited=272, 26997482].
Harrington LB, Doxzen KW, Ma E, ..., Doudna JA (2017) A Broad-Spectrum Inhibitor of CRISPR-Cas9. Cell. [IF=8.479,
Cited=122, 28844692].
Oakes BL, Fellmann C, Rishi H, ..., Savage DF (2019) CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for
Genome Modification. Cell. [IF=8.479, Cited=46, 30633905].
Fozouni P, Son S, Díaz de León Derby M, ..., Ott M (2020) Amplification-free detection of SARS-CoV-2 with CRISPR-Cas13a
and mobile phone microscopy. Cell. [IF=8.479, Cited=309, 33306959].
Al-Shayeb B, Skopintsev P, Soczek KM, ..., Doudna JA (2022) Diverse virus-encoded CRISPR-Cas systems include streamlined
genome editors. Cell. [IF=8.479, Cited=25, 36423580].
Bouhaddou M, Reuschl AK, Polacco BJ, ..., Krogan NJ (2023) SARS-CoV-2 variants evolve convergent strategies to remodel
the host response. Cell. [IF=8.479, Cited=9, 37738970].
Tsuchida CA, Brandes N, Bueno R, ..., Doudna JA (2023) Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered
T cells. Cell. [IF=8.479, Cited=24, 37794590].
Eggers AR, Chen K, Soczek KM, ..., Doudna JA (2024) Rapid DNA unwinding accelerates genome editing by engineered CRISPR-
Cas9. Cell. [IF=8.479, Cited=0, 38781968].
Blair JD, Hockemeyer D, Doudna JA, ..., Floor SN (2017) Widespread Translational Remodeling during Human Neuronal
Differentiation. Cell Reports. [IF=1.738, Cited=76, 29141229].
Tambe A, East-Seletsky A, Knott GJ, ..., O'Connell MR (2018) RNA Binding and HEPN-Nuclease Activation Are Decoupled in
CRISPR-Cas13a. Cell Reports. [IF=1.738, Cited=52, 30044970].
Hamilton JR, Tsuchida CA, Nguyen DN, ..., Doudna JA (2021) Targeted delivery of CRISPR-Cas9 and transgenes enables
complex immune cell engineering. Cell Reports. [IF=1.738, Cited=59, 34077734].
Tan IL, Perez AR, Lew RJ, ..., Fellmann C (2023) Targeting the non-coding genome and temozolomide signature enables
CRISPR-mediated glioma oncolysis. Cell Reports. [IF=1.738, Cited=2, 37917583].
Heler R, Wright AV, Vucelja M, ..., Marraffini LA (2019) Spacer Acquisition Rates Determine the Immunological Diversity
of the Type II CRISPR-Cas Immune Response. None. [IF=None, Cited=13, 30709780].
Brook CE, Northrup GR, Ehrenberg AJ, ..., Boots M (2021) Optimizing COVID-19 control with asymptomatic surveillance
testing in a university environment. Epidemics. [IF=1.174, Cited=19, 34814094].
Nalefski EA, Patel N, Leung PJY, ..., Madan D (2021) Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for
development of improved CRISPR-Based diagnostics. iScience. [IF=1.12, Cited=29, 34505008].
Adly AN, Bi M, Carlson CR, ..., Morgan DO (2023) Assembly of SARS-CoV-2 ribonucleosomes by truncated
N^∗ variant of the nucleocapsid protein. Journal of Biological Chemistry. [IF=1.122, Cited=1, 37863261].
Staals RHJ, Agari Y, Maki-Yonekura S, ..., Shinkai A (2013) Structure and activity of the RNA-targeting Type III-B
CRISPR-Cas complex of Thermus thermophilus. Molecular Cell. [IF=2.773, Cited=146, 24119403].
Staals RHJ, Zhu Y, Taylor DW, ..., van der Oost J (2014) RNA targeting by the type III-A CRISPR-Cas Csm complex of
Thermus thermophilus. Molecular Cell. [IF=2.773, Cited=168, 25457165].
Wilson RC, Tambe A, Kidwell MA, ..., Doudna JA (2014) Dicer-TRBP complex formation ensures accurate mammalian microRNA
biogenesis. Molecular Cell. [IF=2.773, Cited=135, 25557550].
Sternberg SH, Doudna JA (2015) Expanding the Biologist's Toolkit with CRISPR-Cas9. Molecular Cell. [IF=2.773,
Cited=221, 26000842].
Kranzusch PJ, Wilson SC, Lee ASY, ..., Vance RE (2015) Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3'
cGAMP Signaling. Molecular Cell. [IF=2.773, Cited=128, 26300263].
Ma E, Harrington LB, O'Connell MR, ..., Doudna JA (2015) Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes.
Molecular Cell. [IF=2.773, Cited=61, 26545076].
Floor SN, Doudna JA (2015) Get in LINE: Competition for Newly Minted Retrotransposon Proteins at the Ribosome. Molecular
Cell. [IF=2.773, Cited=2, 26638173].
Nuñez JK, Bai L, Harrington LB, ..., Doudna JA (2016) CRISPR Immunological Memory Requires a Host Factor for
Specificity. Molecular Cell. [IF=2.773, Cited=108, 27211867].
Hochstrasser ML, Taylor DW, Kornfeld JE, ..., Doudna JA (2016) DNA Targeting by a Minimal CRISPR RNA-Guided Cascade.
Molecular Cell. [IF=2.773, Cited=38, 27588603].
Heler R, Wright AV, Vucelja M, ..., Marraffini LA (2016) Mutations in Cas9 Enhance the Rate of Acquisition of Viral
Spacer Sequences during the CRISPR-Cas Immune Response. Molecular Cell. [IF=2.773, Cited=33, 28017588].
East-Seletsky A, O'Connell MR, Burstein D, ..., Doudna JA (2017) RNA Targeting by Functionally Orthogonal Type VI-A
CRISPR-Cas Enzymes. Molecular Cell. [IF=2.773, Cited=124, 28475872].
Jiang F, Liu JJ, Osuna BA, ..., Doudna JA (2018) Temperature-Responsive Competitive Inhibition of CRISPR-Cas9. Molecular
Cell. [IF=2.773, Cited=37, 30595438].
Wright AV, Wang JY, Burstein D, ..., Doudna JA (2019) A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR
System. Molecular Cell. [IF=2.773, Cited=15, 30709710].
Harrington LB, Ma E, Chen JS, ..., Doudna JA (2020) A scoutRNA Is Required for Some Type V CRISPR-Cas Systems. Molecular
Cell. [IF=2.773, Cited=26, 32645367].
Tsuchida CA, Zhang S, Doost MS, ..., Liu JJG (2022) Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome
editing activity. Molecular Cell. [IF=2.773, Cited=15, 35219382].
Huang CJ, Adler BA, Doudna JA (2022) A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression. Molecular
Cell. [IF=2.773, Cited=14, 35659325].
Aggarwal AK, Doudna JA (2005) Protein-nucleic acid interactions: unlocking mysteries old and new. Current Opinion in
Structural Biology. [IF=1.4, Cited=0, 34650322].
Jiang F, Doudna JA (2015) The structural biology of CRISPR-Cas systems. Current Opinion in Structural Biology. [IF=1.4,
Cited=94, 25723899].
Hochstrasser ML, Doudna JA (2014) Cutting it close: CRISPR-associated endoribonuclease structure and function. Trends in
Biochemical Sciences. [IF=2.462, Cited=76, 25468820].
Huang CH, Lee KC, Doudna JA (2018) Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection. Trends in
Cancer. [IF=2.585, Cited=43, 29937048].
Stahl EC, Sabo JK, Kang MH, ..., Doudna JA (2023) Genome editing in the mouse brain with minimally immunogenic Cas9
RNPs. Molecular Therapy. [IF=1.72, Cited=5, 37403358].
Aggarwal AK, Doudna JA (2003) Protein-nucleic acid interactions. Current Opinion in Structural Biology. [IF=1.4,
Cited=0, 34276144].
Palermo G, Chen JS, Ricci CG, ..., McCammon JA (2018) Key role of the REC lobe during CRISPR-Cas9 activation by
'sensing', 'regulating', and 'locking' the catalytic HNH domain. Quarterly Reviews of Biophysics. [IF=1.372, Cited=48, 30555184].
Lobba MJ, Fellmann C, Marmelstein AM, ..., Francis MB (2020) Site-Specific Bioconjugation through Enzyme-Catalyzed
Tyrosine-Cysteine Bond Formation. ACS Central Science. [IF=2.363, Cited=29, 32999931].
Ricci CG, Chen JS, Miao Y, ..., Palermo G (2019) Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated
Molecular Dynamics. ACS Central Science. [IF=2.363, Cited=49, 31041385].
Nuñez JK, Harrington LB, Doudna JA (2016) Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering.
ACS Chemical Biology. [IF=0.963, Cited=58, 26857072].
Green R, Doudna JA (2006) RNAs regulate biology. ACS Chemical Biology. [IF=0.963, Cited=2, 17163766].
Mogilevsky CS, Lobba MJ, Brauer DD, ..., Francis MB (2021) Synthesis of Multi-Protein Complexes through Charge-Directed
Sequential Activation of Tyrosine Residues. Journal of the American Chemical Society. [IF=2.573, Cited=10, 34382787].
Doudna JA, Cech TR (2002) The chemical repertoire of natural ribozymes. Nature. [IF=11.591, Cited=345, 12110898].
Haurwitz RE, Sternberg SH, Doudna JA (2012) Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA.
EMBO Journal. [IF=2.114, Cited=61, 22522703].
Wiedenheft B, Lander GC, Zhou K, ..., Nogales E (2011) Structures of the RNA-guided surveillance complex from a
bacterial immune system. Nature. [IF=11.591, Cited=253, 21938068].
Sternberg SH, Redding S, Jinek M, ..., Doudna JA (2014) DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
Nature. [IF=11.591, Cited=958, 24476820].
O'Connell MR, Oakes BL, Sternberg SH, ..., Doudna JA (2014) Programmable RNA recognition and cleavage by CRISPR/Cas9.
Nature. [IF=11.591, Cited=320, 25274302].
Nuñez JK, Lee ASY, Engelman A, Doudna JA (2015) Integrase-mediated spacer acquisition during CRISPR-Cas adaptive
immunity. Nature. [IF=11.591, Cited=205, 25707795].
Sternberg SH, LaFrance B, Kaplan M, Doudna JA (2015) Conformational control of DNA target cleavage by CRISPR-Cas9.
Nature. [IF=11.591, Cited=298, 26524520].
Nuñez JK, Harrington LB, Kranzusch PJ, ..., Doudna JA (2015) Foreign DNA capture during CRISPR-Cas adaptive immunity.
Nature. [IF=11.591, Cited=112, 26503043].
East-Seletsky A, O'Connell MR, Knight SC, ..., Doudna JA (2016) Two distinct RNase activities of CRISPR-C2c2 enable
guide-RNA processing and RNA detection. Nature. [IF=11.591, Cited=442, 27669025].
Burstein D, Harrington LB, Strutt SC, ..., Banfield JF (2016) New CRISPR-Cas systems from uncultivated microbes. Nature.
[IF=11.591, Cited=263, 28005056].
Chen JS, Dagdas YS, Kleinstiver BP, ..., Doudna JA (2017) Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.
Nature. [IF=11.591, Cited=542, 28931002].
Oakes BL, Nadler DC, Flamholz A, ..., Savage DF (2016) Profiling of engineering hotspots identifies an allosteric
CRISPR-Cas9 switch. Nature Biotechnology. [IF=8.861, Cited=108, 27136077].
Barrangou R, Doudna JA (2016) Applications of CRISPR technologies in research and beyond. Nature Biotechnology.
[IF=8.861, Cited=374, 27606440].
Staahl BT, Benekareddy M, Coulon-Bainier C, ..., Doudna JA (2017) Efficient genome editing in the mouse brain by local
delivery of engineered Cas9 ribonucleoprotein complexes. Nature Biotechnology. [IF=8.861, Cited=167, 28191903].
Doudna JA (2005) Chemical biology at the crossroads of molecular structure and mechanism. Nature Chemical Biology.
[IF=2.623, Cited=8, 16408062].
Singh D, Sternberg SH, Fei J, ..., Ha T (2016) Real-time observation of DNA recognition and rejection by the RNA-guided
endonuclease Cas9. Nature Communications. [IF=3.268, Cited=128, 27624851].
Chen X, Shen Y, Draper W, ..., Chang HY (2016) ATAC-see reveals the accessible genome by transposase-mediated imaging
and sequencing. Nature Methods. [IF=10.009, Cited=127, 27749837].
Fellmann C, Gowen BG, Lin PC, ..., Corn JE (2016) Cornerstones of CRISPR-Cas in drug discovery and therapy. Nature
Reviews Drug Discovery. [IF=18.471, Cited=201, 28008168].
Mortimer SA, Kidwell MA, Doudna JA (2014) Insights into RNA structure and function from genome-wide studies. Nature
Reviews Genetics. [IF=8.261, Cited=231, 24821474].
Gorski SA, Vogel J, Doudna JA (2017) RNA-based recognition and targeting: sowing the seeds of specificity. Nature
Reviews Molecular Cell Biology. [IF=19.213, Cited=102, 28196981].
Nuñez JK, Kranzusch PJ, Noeske J, ..., Doudna JA (2014) Cas1-Cas2 complex formation mediates spacer acquisition during
CRISPR-Cas adaptive immunity. Nature Structural and Molecular Biology. [IF=2.542, Cited=258, 24793649].
Wright AV, Doudna JA (2016) Protecting genome integrity during CRISPR immune adaptation. Nature Structural and Molecular
Biology. [IF=2.542, Cited=53, 27595346].
Knott GJ, East-Seletsky A, Cofsky JC, ..., Doudna JA (2017) Guide-bound structures of an RNA-targeting A-cleaving
CRISPR-Cas13a enzyme. Nature Structural and Molecular Biology. [IF=2.542, Cited=60, 28892041].
Doudna JA, Lorsch JR (2005) Ribozyme catalysis: not different, just worse. Nature Structural and Molecular Biology.
[IF=2.542, Cited=83, 15870731].
Harrington LB, Paez-Espino D, Staahl BT, ..., Doudna JA (2017) A thermostable Cas9 with increased lifetime in human
plasma. Nature Communications. [IF=3.268, Cited=91, 29127284].
Moreno-Mateos MA, Fernandez JP, Rouet R, ..., Giraldez AJ (2017) CRISPR-Cpf1 mediates efficient homology-directed repair
and temperature-controlled genome editing. Nature Communications. [IF=3.268, Cited=136, 29222508].
Kundert K, Lucas JE, Watters KE, ..., Kortemme T (2019) Controlling CRISPR-Cas9 with ligand-activated and ligand-
deactivated sgRNAs. Nature Communications. [IF=3.268, Cited=61, 31073154].
Liu TY, Liu JJ, Aditham AJ, ..., Doudna JA (2019) Target preference of Type III-A CRISPR-Cas complexes at the
transcription bubble. Nature Communications. [IF=3.268, Cited=25, 31278272].
Wang JY, Hoel CM, Al-Shayeb B, ..., Doudna JA (2021) Structural coordination between active sites of a CRISPR reverse
transcriptase-integrase complex. Nature Communications. [IF=3.268, Cited=10, 33958590].
Shams A, Higgins SA, Fellmann C, ..., Savage DF (2021) Comprehensive deletion landscape of CRISPR-Cas9 identifies
minimal RNA-guided DNA-binding modules. Nature Communications. [IF=3.268, Cited=16, 34580310].
Hiatt J, Hultquist JF, McGregor MJ, ..., Krogan NJ (2022) A functional map of HIV-host interactions in primary human T
cells. Nature Communications. [IF=3.268, Cited=19, 35365639].
Barger CJ, Suwala AK, Soczek KM, ..., Costello JF (2022) Conserved features of TERT promoter duplications reveal an
activation mechanism that mimics hotspot mutations in cancer. Nature Communications. [IF=3.268, Cited=6, 36114166].
Taha TY, Chen IP, Hayashi JM, ..., Ott M (2023) Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron
BA.1 variant through NSP6. Nature Communications. [IF=3.268, Cited=16, 37085489].
Lou YC, Rubin BE, Schoelmerich MC, ..., Banfield JF (2023) Infant microbiome cultivation and metagenomic analysis reveal
Bifidobacterium 2'-fucosyllactose utilization can be facilitated by coexisting species. Nature Communications.
[IF=3.268, Cited=0, 37973815].
Chen K, Stahl EC, Kang MH, ..., Doudna JA (2024) Engineering self-deliverable ribonucleoproteins for genome editing in
the brain. Nature Communications. [IF=3.268, Cited=1, 38409124].
Chen K, Stahl EC, Kang MH, ..., Doudna JA (2024) Author Correction: Engineering self-deliverable ribonucleoproteins for
genome editing in the brain. Nature Communications. [IF=3.268, Cited=0, 38693162].
Lee K, Conboy M, Park HM, ..., Murthy N (2017) Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in
vivo induces homology-directed DNA repair. Nature Biomedical Engineering. [IF=3.79, Cited=319, 29805845].
Chandrasekaran SS, Agrawal S, Fanton A, ..., Hsu PD (2022) Rapid detection of SARS-CoV-2 RNA in saliva via Cas13. Nature
Biomedical Engineering. [IF=3.79, Cited=29, 35953650].
He C, Keren R, Whittaker ML, ..., Banfield JF (2021) Genome-resolved metagenomics reveals site-specific diversity of
episymbiotic CPR bacteria and DPANN archaea in groundwater ecosystems. Nature Microbiology. [IF=4.448, Cited=70, 33495623].
Rubin BE, Diamond S, Cress BF, ..., Doudna JA (2021) Species- and site-specific genome editing in complex bacterial
communities. Nature Microbiology. [IF=4.448, Cited=66, 34873292].
Adler BA, Hessler T, Cress BF, ..., Doudna JA (2022) Broad-spectrum CRISPR-Cas13a enables efficient phage genome
editing. Nature Microbiology. [IF=4.448, Cited=25, 36316451].
Wang JY, Pausch P, Doudna JA (2022) Structural biology of CRISPR-Cas immunity and genome editing enzymes. Nature Reviews
Microbiology. [IF=6.979, Cited=38, 35562427].
Liu JJ, Orlova N, Oakes BL, ..., Doudna JA (2019) CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature. [IF=11.591, Cited=187, 30718774].
Liu JJ, Orlova N, Oakes BL, ..., Doudna JA (2019) Author Correction: CasX enzymes comprise a distinct family of RNA-
guided genome editors. Nature. [IF=11.591, Cited=1, 30944483].
Doudna JA (2020) The promise and challenge of therapeutic genome editing. Nature. [IF=11.591, Cited=339, 32051598].
Al-Shayeb B, Sachdeva R, Chen LX, ..., Banfield JF (2020) Clades of huge phages from across Earth's ecosystems. Nature.
[IF=11.591, Cited=184, 32051592].
Saha K, Sontheimer EJ, Brooks PJ, ..., Zhou J (2021) The NIH Somatic Cell Genome Editing program. Nature. [IF=11.591,
Cited=51, 33828315].
Suryawanshi RK, Chen IP, Ma T, ..., Ott M (2022) Limited cross-variant immunity from SARS-CoV-2 Omicron without
vaccination. Nature. [IF=11.591, Cited=120, 35584773].
Al-Shayeb B, Schoelmerich MC, West-Roberts J, ..., Banfield JF (2022) Borgs are giant genetic elements with potential to
expand metabolic capacity. Nature. [IF=11.591, Cited=17, 36261517].
Wang JY, Tuck OT, Skopintsev P, ..., Doudna JA (2023) Genome expansion by a CRISPR trimmer-integrase. Nature.
[IF=11.591, Cited=4, 37316664].
Kliegman M, Zaghlula M, Abrahamson S, ..., Doudna JA (2024) A roadmap for affordable genetic medicines. Nature.
[IF=11.591, Cited=0, 39019069].
Richter MF, Zhao KT, Eton E, ..., Liu DR (2020) Phage-assisted evolution of an adenine base editor with improved Cas
domain compatibility and activity. Nature Biotechnology. [IF=8.861, Cited=357, 32433547].
Richter MF, Zhao KT, Eton E, ..., Liu DR (2020) Author Correction: Phage-assisted evolution of an adenine base editor
with improved Cas domain compatibility and activity. Nature Biotechnology. [IF=8.861, Cited=9, 32433548].
Jones SK, Hawkins JA, Johnson NV, ..., Finkelstein IJ (2020) Massively parallel kinetic profiling of natural and
engineered CRISPR nucleases. Nature Biotechnology. [IF=8.861, Cited=51, 32895548].
Colognori D, Trinidad M, Doudna JA (2023) Precise transcript targeting by CRISPR-Csm complexes. Nature Biotechnology.
[IF=8.861, Cited=17, 36690762].
Hamilton JR, Chen E, Perez BS, ..., Doudna JA (2024) In vivo human T cell engineering with enveloped delivery vehicles.
Nature Biotechnology. [IF=8.861, Cited=6, 38212493].
Shivram H, Cress BF, Knott GJ, Doudna JA (2020) Controlling and enhancing CRISPR systems. Nature Chemical Biology.
[IF=2.623, Cited=45, 33328654].
Liu TY, Knott GJ, Smock DCJ, ..., Doudna JA (2021) Accelerated RNA detection using tandem CRISPR nucleases. Nature
Chemical Biology. [IF=2.623, Cited=74, 34354262].
Liu TY, Knott GJ, Smock DCJ, ..., Doudna JA (2021) Publisher Correction: Accelerated RNA detection using tandem CRISPR
nucleases. Nature Chemical Biology. [IF=2.623, Cited=1, 34616098].
Yoon PH, Adler BA, Doudna JA (2023) To TnpB or not TnpB? Cas12 is the answer. Nature Chemical Biology. [IF=2.623,
Cited=2, 36797405].
Knott GJ, Thornton BW, Lobba MJ, ..., Doudna JA (2019) Broad-spectrum enzymatic inhibition of CRISPR-Cas12a. Nature
Structural and Molecular Biology. [IF=2.542, Cited=52, 30936531].
Pausch P, Soczek KM, Herbst DA, ..., Doudna JA (2021) DNA interference states of the hypercompact CRISPR-CasΦ effector.
Nature Structural and Molecular Biology. [IF=2.542, Cited=34, 34381246].
Cofsky JC, Soczek KM, Knott GJ, ..., Doudna JA (2022) CRISPR-Cas9 bends and twists DNA to read its sequence. Nature
Structural and Molecular Biology. [IF=2.542, Cited=26, 35422516].
Hultquist JF, Hiatt J, Schumann K, ..., Krogan NJ (2019) CRISPR-Cas9 genome engineering of primary CD4⁺ T
cells for the interrogation of HIV-host factor interactions. None. [IF=None, Cited=64, 30559373].
Collins FS, Doudna JA, Lander E, ..., Rotimi CN (2021) Human Molecular Genetics and Genomics - Important Advances and
Exciting Possibilities. New England Journal of Medicine. [IF=17.194, Cited=10, 33393745].
Ji H, Fraser CS, Yu Y, ..., Doudna JA (2004) Coordinated assembly of human translation initiation complexes by the
hepatitis C virus internal ribosome entry site RNA. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=123, 15563596].
MacRae IJ, Ma E, Zhou M, ..., Doudna JA (2008) In vitro reconstitution of the human RISC-loading complex. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=243, 18178619].
Zhou M, Sandercock AM, Fraser CS, ..., Robinson CV (2008) Mass spectrometry reveals modularity and a complete subunit
interaction map of the eukaryotic translation factor eIF3. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=174, 18599441].
Mehle A, Doudna JA (2009) Adaptive strategies of the influenza virus polymerase for replication in humans. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=251, 19995968].
Wiedenheft B, van Duijn E, Bultema JB, ..., Doudna JA (2011) RNA-guided complex from a bacterial immune system enhances
target recognition through seed sequence interactions. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=284, 21536913].
Lucks JB, Mortimer SA, Trapnell C, ..., Arkin AP (2011) Multiplexed RNA structure characterization with selective
2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq). Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=230, 21642531].
Aviran S, Trapnell C, Lucks JB, ..., Pachter L (2011) Modeling and automation of sequencing-based characterization of
RNA structure. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=74, 21642536].
Sun C, Todorovic A, Querol-Audí J, ..., Cate JHD (2011) Functional reconstitution of human eukaryotic translation
initiation factor 3 (eIF3). Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=76, 22135459].
Koh HR, Kidwell MA, Ragunathan K, ..., Myong S (2012) ATP-independent diffusion of double-stranded RNA binding proteins.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=35, 23251028].
Lee HY, Haurwitz RE, Apffel A, ..., Doudna JA (2013) RNA-protein analysis using a conditional CRISPR nuclease.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=48, 23493562].
Hochstrasser ML, Taylor DW, Bhat P, ..., Doudna JA (2014) CasA mediates Cas3-catalyzed target degradation during CRISPR
RNA-guided interference. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=133, 24748111].
Wright AV, Sternberg SH, Taylor DW, ..., Doudna JA (2015) Rational design of a split-Cas9 enzyme complex. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=149, 25713377].
Schumann K, Lin S, Boyer E, ..., Marson A (2015) Generation of knock-in primary human T cells using Cas9
ribonucleoproteins. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=394, 26216948].
Kaya E, Doxzen KW, Knoll KR, ..., Doudna JA (2016) A bacterial Argonaute with noncanonical guide RNA specificity.
Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=70, 27035975].
Boyle EA, Andreasson JOL, Chircus LM, ..., Greenleaf WJ (2017) High-throughput biochemical profiling reveals sequence
determinants of dCas9 off-target binding and unbinding. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=96, 28495970].
Lapinaite A, Doudna JA, Cate JHD (2018) Programmable RNA recognition using a CRISPR-associated Argonaute. Proceedings of
the National Academy of Sciences of the United States of America. [IF=2.765, Cited=19, 29531059].
Cao Y, Ma E, Cestellos-Blanco S, ..., Yang P (2019) Nontoxic nanopore electroporation for effective intracellular
delivery of biological macromolecules. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=51, 30923112].
Battle DJ, Doudna JA (2002) Specificity of RNA-RNA helix recognition. Proceedings of the National Academy of Sciences of
the United States of America. [IF=2.765, Cited=63, 12189204].
Cao Y, Ma E, Cestellos-Blanco S, ..., Yang P (2019) Reply to Nathamgari et al.: Nanopore electroporation for
intracellular delivery of biological macromolecules. Proceedings of the National Academy of Sciences of the United
States of America. [IF=2.765, Cited=3, 31662468].
Ivanov IE, Wright AV, Cofsky JC, ..., Bryant Z (2020) Cas9 interrogates DNA in discrete steps modulated by mismatches
and supercoiling. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=38, 32123105].
Watters KE, Shivram H, Fellmann C, ..., Doudna JA (2020) Potent CRISPR-Cas9 inhibitors from Staphylococcus
genomes. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=31, 32156733].
Amen AM, Fellmann C, Soczek KM, ..., Costello JF (2021) Cancer-specific loss of TERT activation sensitizes
glioblastoma to DNA damage. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765,
Cited=22, 33758097].
Syed AM, Ciling A, Taha TY, ..., Doudna JA (2022) Omicron mutations enhance infectivity and reduce antibody
neutralization of SARS-CoV-2 virus-like particles. Proceedings of the National Academy of Sciences of the United States
of America. [IF=2.765, Cited=99, 35858386].
Chen E, Lin-Shiao E, Trinidad M, ..., Doudna JA (2022) Decorating chromatin for enhanced genome editing using CRISPR-
Cas9. Proceedings of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=9, 36459645].
Li Z, Zhong Z, Wu Z, ..., Jacobsen SE (2023) Genome editing in plants using the compact editor CasΦ. Proceedings of the
National Academy of Sciences of the United States of America. [IF=2.765, Cited=7, 36652483].
Tsuchida CA, Wasko KM, Hamilton JR, Doudna JA (2024) Targeted nonviral delivery of genome editors in vivo. Proceedings
of the National Academy of Sciences of the United States of America. [IF=2.765, Cited=1, 38437567].
Morgan CJ, Enustun E, Armbruster EG, ..., Pogliano J (2024) An essential and highly selective protein import pathway
encoded by nucleus-forming phage. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=0, 38687783].
Kidwell MA, Chan JM, Doudna JA (2014) Evolutionarily conserved roles of the dicer helicase domain in regulating RNA
interference processing. Journal of Biological Chemistry. [IF=1.122, Cited=11, 25135636].
Floor SN, Condon KJ, Sharma D, ..., Doudna JA (2015) Autoinhibitory Interdomain Interactions and Subfamily-specific
Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3. Journal of Biological Chemistry. [IF=1.122,
Cited=43, 26598523].
Liu TY, Doudna JA (2020) Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation. Journal of
Biological Chemistry. [IF=1.122, Cited=25, 32817336].
Bondy-Denomy J, Davidson AR, Doudna JA, ..., Wiedenheft B (2018) A Unified Resource for Tracking Anti-CRISPR Names.
CRISPR Journal. [IF=0.697, Cited=52, 31021273].
Eitzinger S, Asif A, Watters KE, ..., Minhas FUAA (2020) Machine learning predicts new anti-CRISPR proteins. Nucleic
Acids Research. [IF=4.663, Cited=44, 32286628].
Jakhanwal S, Cress BF, Maguin P, ..., Doudna JA (2021) A CRISPR-Cas9-integrase complex generates precise DNA fragments
for genome integration. Nucleic Acids Research. [IF=4.663, Cited=11, 33693715].
Lin-Shiao E, Pfeifer WG, Shy BR, ..., Doudna JA (2022) CRISPR-Cas9-mediated nuclear transport and genomic integration of
nanostructured genes in human primary cells. Nucleic Acids Research. [IF=4.663, Cited=17, 35104875].
Ma E, Chen K, Shi H, ..., Doudna JA (2022) Improved genome editing by an engineered CRISPR-Cas12a. Nucleic Acids
Research. [IF=4.663, Cited=13, 36537251].
Otoupal PB, Cress BF, Doudna JA, Schoeniger JS (2022) CRISPR-RNAa: targeted activation of translation using dCas13
fusions to translation initiation factors. Nucleic Acids Research. [IF=4.663, Cited=13, 35950485].
Yoon PH, Skopintsev P, Shi H, ..., Doudna JA (2023) Eukaryotic RNA-guided endonucleases evolved from a unique clade of
bacterial enzymes. Nucleic Acids Research. [IF=4.663, Cited=2, 37971304].
Adler BA, Trinidad MI, Bellieny-Rabelo D, ..., Doudna JA (2024) CasPEDIA Database: a functional classification system
for class 2 CRISPR-Cas enzymes. Nucleic Acids Research. [IF=4.663, Cited=2, 37889041].
Enustun E, Armbruster EG, Lee J, ..., Corbett KD (2024) A phage nucleus-associated RNA-binding protein is required for
jumbo phage infection. Nucleic Acids Research. [IF=4.663, Cited=1, 38554115].
Zhao H, Syed AM, Khalid MM, ..., Schuck P (2024) Assembly of SARS-CoV-2 nucleocapsid protein with nucleic acid. Nucleic
Acids Research. [IF=4.663, Cited=0, 38587193].
Kapral GJ, Jain S, Noeske J, ..., Richardson JS (2014) New tools provide a second look at HDV ribozyme structure,
dynamics and cleavage. Nucleic Acids Research. [IF=4.663, Cited=17, 25326328].
Gaj T, Staahl BT, Rodrigues GMC, ..., Schaffer DV (2017) Targeted gene knock-in by homology-directed genome editing
using Cas9 ribonucleoprotein and AAV donor delivery. Nucleic Acids Research. [IF=4.663, Cited=46, 28334779].
Brook CE, Northrup GR, Ehrenberg AJ, ..., Boots M (2021) Optimizing COVID-19 control with asymptomatic surveillance
testing in a university environment. None. [IF=None, Cited=0, 33442708].
Stahl EC, Tsuchida CA, Hamilton JR, ..., Doudna JA (2020) IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-
CoV-2. None. [IF=None, Cited=2, 33330883].
Agrawal S, Fanton A, Chandrasekaran SS, ..., Hsu PD (2021) Rapid, point-of-care molecular diagnostics with Cas13. None.
[IF=None, Cited=0, 33354689].
Hamilton JR, Stahl EC, Tsuchida CA, ..., Doudna JA (2021) Robotic RNA extraction for SARS-CoV-2 surveillance using
saliva samples. None. [IF=None, Cited=0, 33532798].
Liu TY, Knott GJ, Smock DCJ, ..., Doudna JA (2021) Accelerated RNA detection using tandem CRISPR nucleases. None.
[IF=None, Cited=0, 33791736].
Syed AM, Ciling A, Khalid MM, ..., Doudna JA (2022) Omicron mutations enhance infectivity and reduce antibody
neutralization of SARS-CoV-2 virus-like particles. None. [IF=None, Cited=0, 34981067].
Tsuchida CA, Brandes N, Bueno R, ..., Doudna JA (2023) Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered
T cells. None. [IF=None, Cited=0, 36993359].
Armbruster EG, Lee J, Hutchings J, ..., Pogliano J (2023) Sequential membrane- and protein-bound organelles
compartmentalize genomes during phage infection. None. [IF=None, Cited=0, 37781618].
Enustun E, Armbruster EG, Lee J, ..., Corbett KD (2023) A phage nucleus-associated RNA-binding protein is required for
jumbo phage infection. None. [IF=None, Cited=0, 37790334].
Zhao H, Syed AM, Khalid MM, ..., Schuck P (2023) Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic
acid. None. [IF=None, Cited=0, 38045338].
Tuck OT, Adler BA, Armbruster EG, ..., Doudna JA (2024) Hachiman is a genome integrity sensor. None. [IF=None, Cited=0, 38464307].
Shulgina Y, Trinidad MI, Langeberg CJ, ..., Cate JHD (2024) RNA language models predict mutations that improve RNA
function. None. [IF=None, Cited=0, 38617247].
Ramadoss GN, Namaganda SJ, Hamilton JR, ..., Conklin BR (2024) Neuronal DNA repair reveals strategies to influence
CRISPR editing outcomes. None. [IF=None, Cited=0, 38979269].
Xia C, Colognori D, Jiang X, ..., Doudna JA (2024) Single-molecule live-cell RNA imaging with CRISPR-Csm. None.
[IF=None, Cited=0, 39071319].
Ngo W, Peukes JT, Baldwin A, ..., Doudna JA (2024) Mechanism-guided engineering of a minimal biological particle for
genome editing. None. [IF=None, Cited=0, 39091760].
Soczek KM, Cofsky JC, Tuck OT, ..., Doudna JA (2024) CRISPR-Cas12a bends DNA to destabilize base pairs during target
interrogation. None. [IF=None, Cited=0, 39131396].
Shin J, Jiang F, Liu JJ, ..., Doudna JA (2017) Disabling Cas9 by an anti-CRISPR DNA mimic. Science advances. [IF=2.861,
Cited=162, 28706995].
Dagdas YS, Chen JS, Sternberg SH, ..., Yildiz A (2017) A conformational checkpoint between DNA binding and cleavage by
CRISPR-Cas9. Science advances. [IF=2.861, Cited=135, 28808686].
Boyle EA, Becker WR, Bai HB, ..., Greenleaf WJ (2021) Quantification of Cas9 binding and cleavage across diverse guide
sequences maps landscapes of target engagement. Science advances. [IF=2.861, Cited=11, 33608277].
Siridechadilok B, Fraser CS, Hall RJ, ..., Nogales E (2005) Structural roles for human translation factor eIF3 in
initiation of protein synthesis. Science. [IF=7.729, Cited=191, 16322461].
Macrae IJ, Zhou K, Li F, ..., Doudna JA (2006) Structural basis for double-stranded RNA processing by Dicer. Science.
[IF=7.729, Cited=540, 16410517].
Gilbert WV, Zhou K, Butler TK, Doudna JA (2007) Cap-independent translation is required for starvation-induced
differentiation in yeast. Science. [IF=7.729, Cited=134, 17761883].
Haurwitz RE, Jinek M, Wiedenheft B, ..., Doudna JA (2010) Sequence- and structure-specific RNA processing by a CRISPR
endonuclease. Science. [IF=7.729, Cited=422, 20829488].
Ataide SF, Schmitz N, Shen K, ..., Ban N (2011) The crystal structure of the signal recognition particle in complex with
its receptor. Science. [IF=7.729, Cited=92, 21330537].
Kaya E, Doudna JA (2012) Biochemistry. Guided tour to the heart of RISC. Science. [IF=7.729, Cited=5, 22628640].
Jinek M, Chylinski K, Fonfara I, ..., Charpentier E (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive
bacterial immunity. Science. [IF=7.729, Cited=1000, 22745249].
Jinek M, Jiang F, Taylor DW, ..., Doudna JA (2014) Structures of Cas9 endonucleases reveal RNA-mediated conformational
activation. Science. [IF=7.729, Cited=573, 24505130].
Doudna JA, Charpentier E (2014) Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science.
[IF=7.729, Cited=1000, 25430774].
Taylor DW, Zhu Y, Staals RHJ, ..., Doudna JA (2015) Structural biology. Structures of the CRISPR-Cmr complex reveal mode
of RNA target positioning. Science. [IF=7.729, Cited=80, 25837515].
Baltimore D, Berg P, Botchan M, ..., Yamamoto KR (2015) Biotechnology. A prudent path forward for genomic engineering
and germline gene modification. Science. [IF=7.729, Cited=225, 25791083].
Jiang F, Zhou K, Ma L, ..., Doudna JA (2015) STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA
recognition. Science. [IF=7.729, Cited=285, 26113724].
Knight SC, Xie L, Deng W, ..., Tjian R (2015) Dynamics of CRISPR-Cas9 genome interrogation in living cells. Science.
[IF=7.729, Cited=187, 26564855].
Jiang F, Taylor DW, Chen JS, ..., Doudna JA (2016) Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
Science. [IF=7.729, Cited=311, 26841432].
Wright AV, Liu JJ, Knott GJ, ..., Doudna JA (2017) Structures of the CRISPR genome integration complex. Science.
[IF=7.729, Cited=78, 28729350].
Chen JS, Ma E, Harrington LB, ..., Doudna JA (2018) CRISPR-Cas12a target binding unleashes indiscriminate single-
stranded DNase activity. Science. [IF=7.729, Cited=1000, 29449511].
Knott GJ, Doudna JA (2018) CRISPR-Cas guides the future of genetic engineering. Science. [IF=7.729, Cited=506, 30166482].
Watters KE, Fellmann C, Bai HB, ..., Doudna JA (2018) Systematic discovery of natural CRISPR-Cas12a inhibitors. Science.
[IF=7.729, Cited=94, 30190307].
Harrington LB, Burstein D, Chen JS, ..., Doudna JA (2018) Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
Science. [IF=7.729, Cited=344, 30337455].
Hamilton JR, Doudna JA (2020) Knocking out barriers to engineered cell activity. Science. [IF=7.729, Cited=5, 32029685].
Lapinaite A, Knott GJ, Palumbo CM, ..., Doudna JA (2020) DNA capture by a CRISPR-Cas9-guided adenine base editor.
Science. [IF=7.729, Cited=74, 32732424].
Pausch P, Al-Shayeb B, Bisom-Rapp E, ..., Doudna JA (2020) CRISPR-CasΦ from huge phages is a hypercompact genome editor.
Science. [IF=7.729, Cited=203, 32675376].
Syed AM, Taha TY, Tabata T, ..., Doudna JA (2021) Rapid assessment of SARS-CoV-2-evolved variants using virus-like
particles. Science. [IF=7.729, Cited=139, 34735219].
Wang JY, Doudna JA (2023) CRISPR technology: A decade of genome editing is only the beginning. Science. [IF=7.729,
Cited=139, 36656942].
Yoon PH, Zhang Z, Loi KJ, ..., Doudna JA (2024) Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases.
Science. [IF=7.729, Cited=0, 39024377].
Mehle A, Dugan VG, Taubenberger JK, Doudna JA (2011) Reassortment and mutation of the avian influenza virus polymerase
PA subunit overcome species barriers. Journal of Virology. [IF=1.075, Cited=86, 22090127].
Coyle SM, Gilbert WV, Doudna JA (2008) Direct link between RACK1 function and localization at the ribosome in vivo.
Molecular and Cellular Biology. [IF=1.026, Cited=107, 19114558].
Jiang F, Doudna JA (2017) CRISPR-Cas9 Structures and Mechanisms. Annual Review of Biophysics. [IF=3.276, Cited=711, 28375731].
Wilson RC, Doudna JA (2013) Molecular mechanisms of RNA interference. Annual Review of Biophysics. [IF=3.276,
Cited=504, 23654304].
Doudna JA, Batey RT (2004) Structural insights into the signal recognition particle. Annual Review of Biochemistry.
[IF=5.273, Cited=88, 15189152].
Lintner NG, McClure KF, Petersen D, ..., Cate JHD (2017) Selective stalling of human translation through small-molecule
engagement of the ribosome nascent chain. PLoS Biology. [IF=2.285, Cited=53, 28323820].
Liu TY, Iavarone AT, Doudna JA (2017) RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type III-A CRISPR-
Cas System. PLoS ONE. [IF=1.253, Cited=49, 28114398].
Doxzen KW, Doudna JA (2017) DNA recognition by an RNA-guided bacterial Argonaute. PLoS ONE. [IF=1.253, Cited=28, 28520746].
Ehrenberg AJ, Moehle EA, Brook CE, ..., Doudna JA (2021) Launching a saliva-based SARS-CoV-2 surveillance testing
program on a university campus. PLoS ONE. [IF=1.253, Cited=14, 34038425].
Hamilton JR, Stahl EC, Tsuchida CA, ..., Doudna JA (2021) Robotic RNA extraction for SARS-CoV-2 surveillance using
saliva samples. PLoS ONE. [IF=1.253, Cited=10, 34351984].
Stahl EC, Gopez AR, Tsuchida CA, ..., Doudna JA (2021) LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and
wastewater samples. PLoS ONE. [IF=1.253, Cited=4, 34758033].
Cofsky JC, Knott GJ, Gee CL, Doudna JA (2022) Crystal structure of an RNA/DNA strand exchange junction. PLoS ONE.
[IF=1.253, Cited=2, 35436289].
Lo TW, Pickle CS, Lin S, ..., Meyer BJ (2013) Precise and heritable genome editing in evolutionarily diverse nematodes
using TALENs and CRISPR/Cas9 to engineer insertions and deletions. Genetics. [IF=1.102, Cited=119, 23934893].
Oh S, Flynn RA, Floor SN, ..., Cho YJ (2016) Medulloblastoma-associated DDX3 variant selectively alters the
translational response to stress. Oncotarget. [IF=0.666, Cited=40, 27058758].
Cofsky JC, Doudna JA (2020) Attachment of a ³²P-phosphate to the 3' Terminus of a DNA Oligonucleotide. Bio-
protocol. [IF=0.267, Cited=0, 33659442].
Chen LX, Al-Shayeb B, Méheust R, ..., Banfield JF (2019) Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have
Novel and Unexpectedly Abundant CRISPR-Cas Systems. Frontiers in Microbiology. [IF=1.331, Cited=20, 31130929].
Shim H, Shivram H, Lei S, ..., Banfield JF (2021) Diverse ATPase Proteins in Mobilomes Constitute a Large Potential Sink
for Prokaryotic Host ATP. Frontiers in Microbiology. [IF=1.331, Cited=5, 34305853].
Mehle A, Doudna JA (2010) A host of factors regulating influenza virus replication. Viruses. [IF=1.071, Cited=22, 21994648].
Bai Y, Tambe A, Zhou K, Doudna JA (2014) RNA-guided assembly of Rev-RRE nuclear export complexes. eLife. [IF=1.743,
Cited=68, 25163983].
Lin S, Staahl BT, Alla RK, Doudna JA (2014) Enhanced homology-directed human genome engineering by controlled timing of
CRISPR/Cas9 delivery. eLife. [IF=1.743, Cited=645, 25497837].
Floor SN, Doudna JA (2016) Tunable protein synthesis by transcript isoforms in human cells. eLife. [IF=1.743,
Cited=141, 26735365].
Isaac RS, Jiang F, Doudna JA, ..., Almeida R (2016) Nucleosome breathing and remodeling constrain CRISPR-Cas9 function.
eLife. [IF=1.743, Cited=105, 27130520].
Carlson LA, Bai Y, Keane SC, ..., Hurley JH (2016) Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-
bound Gag assemblies. eLife. [IF=1.743, Cited=26, 27343348].
Schulze-Gahmen U, Echeverria I, Stjepanovic G, ..., Hurley JH (2016) Insights into HIV-1 proviral transcription from
integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex. eLife. [IF=1.743, Cited=27, 27731797].
Strutt SC, Torrez RM, Kaya E, ..., Doudna JA (2018) RNA-dependent RNA targeting by CRISPR-Cas9. eLife. [IF=1.743,
Cited=84, 29303478].
Knott GJ, Cress BF, Liu JJ, ..., Doudna JA (2019) Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
eLife. [IF=1.743, Cited=26, 31397669].
Cofsky JC, Karandur D, Huang CJ, ..., Doudna JA (2020) CRISPR-Cas12a exploits R-loop asymmetry to form double-strand
breaks. eLife. [IF=1.743, Cited=38, 32519675].

Publication with MISSING institution:

Ferré-D'Amaré AR, Zhou K, Doudna JA (1998) A general module for RNA crystallization. Journal of Molecular Biology.
[IF=1.281, Cited=63, 9641982].
Kieft JS, Zhou K, Jubin R, ..., Doudna JA (1999) The hepatitis C virus internal ribosome entry site adopts an ion-
dependent tertiary fold. Journal of Molecular Biology. [IF=1.281, Cited=151, 10497018].
Ferré-D'Amaré AR, Doudna JA (2000) Crystallization and structure determination of a hepatitis delta virus ribozyme: use
of the RNA-binding protein U1A as a crystallization module. Journal of Molecular Biology. [IF=1.281, Cited=97, 10623545].
Batey RT, Sagar MB, Doudna JA (2001) Structural and energetic analysis of RNA recognition by a universally conserved
protein from the signal recognition particle. Journal of Molecular Biology. [IF=1.281, Cited=63, 11243816].
Doudna JA, Sontheimer EJ (2014) Methods in Enzymology. The use of CRISPR/Cas9, ZFNs, and TALENs in generating site-
specific genome alterations. Preface. None. [IF=None, Cited=17, 25398356].
Qi LS, Larson MH, Gilbert LA, ..., Lim WA (2013) Repurposing CRISPR as an RNA-guided platform for sequence-specific
control of gene expression. Cell. [IF=8.479, Cited=1000, 23452860].
Gilbert LA, Larson MH, Morsut L, ..., Qi LS (2013) CRISPR-mediated modular RNA-guided regulation of transcription in
eukaryotes. Cell. [IF=8.479, Cited=1000, 23849981].
Qi LS, Larson MH, Gilbert LA, ..., Lim WA (2021) Repurposing CRISPR as an RNA-guided platform for sequence-specific
control of gene expression. Cell. [IF=8.479, Cited=24, 33545038].
Kranzusch PJ, Lee ASY, Berger JM, Doudna JA (2013) Structure of human cGAS reveals a conserved family of second-
messenger enzymes in innate immunity. Cell Reports. [IF=1.738, Cited=212, 23707061].
Karbstein K, Doudna JA (2004) RNA: primed for packing? None. [IF=None, Cited=1, 15123272].
Mehle A, Doudna JA (2008) An inhibitory activity in human cells restricts the function of an avian-like influenza virus
polymerase. None. [IF=None, Cited=123, 18692771].
Wu S, Ke A, Doudna JA (2006) A fast and efficient procedure to produce scFvs specific for large macromolecular
complexes. Journal of Immunological Methods. [IF=0.649, Cited=12, 17126854].
Karbstein K, Doudna JA (2005) GTP-dependent formation of a ribonucleoprotein subcomplex required for ribosome
biogenesis. Journal of Molecular Biology. [IF=1.281, Cited=30, 16376378].
Ma E, MacRae IJ, Kirsch JF, Doudna JA (2008) Autoinhibition of human dicer by its internal helicase domain. Journal of
Molecular Biology. [IF=1.281, Cited=148, 18508075].
Chakravarthy S, Sternberg SH, Kellenberger CA, Doudna JA (2010) Substrate-specific kinetics of Dicer-catalyzed RNA
processing. Journal of Molecular Biology. [IF=1.281, Cited=94, 20932845].
Ma E, Zhou K, Kidwell MA, Doudna JA (2012) Coordinated activities of human dicer domains in regulatory RNA processing.
Journal of Molecular Biology. [IF=1.281, Cited=44, 22727743].
Karbstein K, Jonas S, Doudna JA (2005) An essential GTPase promotes assembly of preribosomal RNA processing complexes.
Molecular Cell. [IF=2.773, Cited=57, 16307926].
Fraser CS, Berry KE, Hershey JWB, Doudna JA (2007) eIF3j is located in the decoding center of the human 40S ribosomal
subunit. Molecular Cell. [IF=2.773, Cited=86, 17588516].
Fabian MR, Mathonnet G, Sundermeier T, ..., Sonenberg N (2009) Mammalian miRNA RISC recruits CAF1 and PABP to affect
PABP-dependent deadenylation. Molecular Cell. [IF=2.773, Cited=253, 19716330].
Jinek M, Coyle SM, Doudna JA (2011) Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay.
Molecular Cell. [IF=2.773, Cited=115, 21362555].
Noland CL, Ma E, Doudna JA (2011) siRNA repositioning for guide strand selection by human Dicer complexes. Molecular
Cell. [IF=2.773, Cited=86, 21726814].
Arribere JA, Doudna JA, Gilbert WV (2011) Reconsidering movement of eukaryotic mRNAs between polysomes and P bodies.
Molecular Cell. [IF=2.773, Cited=90, 22152478].
Sashital DG, Wiedenheft B, Doudna JA (2012) Mechanism of foreign DNA selection in a bacterial adaptive immune system.
Molecular Cell. [IF=2.773, Cited=158, 22521690].
MacRae IJ, Doudna JA (2006) Ribonuclease revisited: structural insights into ribonuclease III family enzymes. Current
Opinion in Structural Biology. [IF=1.4, Cited=145, 17194582].
Sashital DG, Doudna JA (2010) Structural insights into RNA interference. Current Opinion in Structural Biology. [IF=1.4,
Cited=50, 20053548].
Ke A, Ding F, Batchelor JD, Doudna JA (2007) Structural roles of monovalent cations in the HDV ribozyme. Structure.
[IF=1.155, Cited=39, 17355864].
Wiedenheft B, Zhou K, Jinek M, ..., Doudna JA (2009) Structural basis for DNase activity of a conserved protein
implicated in CRISPR-mediated genome defense. Structure. [IF=1.155, Cited=146, 19523907].
Berry KE, Waghray S, Mortimer SA, ..., Doudna JA (2011) Crystal structure of the HCV IRES central domain reveals
strategy for start-codon positioning. Structure. [IF=1.155, Cited=78, 22000514].
Ke A, Doudna JA (2004) Crystallization of RNA and RNA-protein complexes. Methods. [IF=0.927, Cited=86, 15325657].
Couture S, Ellington AD, Gerber AS, ..., Szostak JW (1990) Mutational analysis of conserved nucleotides in a self-
splicing group I intron. Journal of Molecular Biology. [IF=1.281, Cited=40, 1700131].
Cate JH, Doudna JA (2000) Solving large RNA structures by X-ray crystallography. None. [IF=None, Cited=18, 10829280].
Murray JM, Doudna JA (2001) Creative catalysis: pieces of the RNA world jigsaw. Trends in Biochemical Sciences.
[IF=2.462, Cited=3, 11738588].
Strobel SA, Doudna JA (1997) RNA seeing double: close-packing of helices in RNA tertiary structure. Trends in
Biochemical Sciences. [IF=2.462, Cited=25, 9255068].
Cate JH, Doudna JA (1996) Metal-binding sites in the major groove of a large ribozyme domain. Structure. [IF=1.155,
Cited=141, 8939748].
Hanna RL, Gryaznov SM, Doudna JA (2000) A phosphoramidate substrate analog is a competitive inhibitor of the Tetrahymena
group I ribozyme. None. [IF=None, Cited=7, 11094338].
Hanna R, Doudna JA (2000) Metal ions in ribozyme folding and catalysis. Current Opinion in Chemical Biology. [IF=1.51,
Cited=45, 10742186].
Fraser CS, Doudna JA (2007) Quantitative studies of ribosome conformational dynamics. Quarterly Reviews of Biophysics.
[IF=1.372, Cited=4, 18072984].
Kieft JS, Zhou K, Jubin R, Doudna JA (2001) Mechanism of ribosome recruitment by hepatitis C IRES RNA. RNA. [IF=0.956,
Cited=254, 11233977].
Battle DJ, Doudna JA (2001) The stem-loop binding protein forms a highly stable and specific complex with the 3' stem-
loop of histone mRNAs. RNA. [IF=0.956, Cited=58, 11214174].
Wadkins TS, Perrotta AT, Ferré-D'Amaré AR, ..., Been MD (1999) A nested double pseudoknot is required for self-cleavage
activity of both the genomic and antigenomic hepatitis delta virus ribozymes. RNA. [IF=0.956, Cited=50, 10376872].
Kiessling LL, Doudna JA (2018) Spotlight: A Conversation with Laura Kiessling and Jennifer Doudna. ACS Chemical Biology.
[IF=0.963, Cited=0, 29448761].
Kiessling LL, Doudna JA, Johnsson K, ..., Wedde SG (2007) A higher degree of difficulty. ACS Chemical Biology.
[IF=0.963, Cited=0, 17455890].
Ferré-D'Amaré AR, Zhou K, Doudna JA (1998) Crystal structure of a hepatitis delta virus ribozyme. Nature. [IF=11.591,
Cited=446, 9783582].
Basu S, Rambo RP, Strauss-Soukup J, ..., Doudna JA (1998) A specific monovalent metal ion integral to the AA platform of
the RNA tetraloop receptor. None. [IF=None, Cited=108, 9808044].
Doudna JA (1997) RNA structure. A molecular contortionist. Nature. [IF=11.591, Cited=5, 9278040].
Charpentier E, Doudna JA (2013) Biotechnology: Rewriting a genome. Nature. [IF=11.591, Cited=102, 23467164].
Doherty EA, Batey RT, Masquida B, Doudna JA (2001) A universal mode of helix packing in RNA. None. [IF=None, Cited=157, 11276255].
Fukunaga R, Doudna JA (2009) dsRNA with 5' overhangs contributes to endogenous and antiviral RNA silencing pathways in
plants. EMBO Journal. [IF=2.114, Cited=82, 19165150].
Ke A, Zhou K, Ding F, ..., Doudna JA (2004) A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature. [IF=11.591, Cited=166, 15141216].
Jinek M, Doudna JA (2009) A three-dimensional view of the molecular machinery of RNA interference. Nature. [IF=11.591,
Cited=411, 19158786].
Wiedenheft B, Sternberg SH, Doudna JA (2012) RNA-guided genetic silencing systems in bacteria and archaea. Nature.
[IF=11.591, Cited=981, 22337052].
Lee AS, Kranzusch PJ, Doudna JA, Cate JHD (2016) eIF3d is an mRNA cap-binding protein that is required for specialized
translation initiation. Nature. [IF=11.591, Cited=188, 27462815].
Qi L, Haurwitz RE, Shao W, ..., Arkin AP (2012) RNA processing enables predictable programming of gene expression.
Nature Biotechnology. [IF=8.861, Cited=117, 22983090].
Pattanayak V, Lin S, Guilinger JP, ..., Liu DR (2013) High-throughput profiling of off-target DNA cleavage reveals RNA-
programmed Cas9 nuclease specificity. Nature Biotechnology. [IF=8.861, Cited=852, 23934178].
Fraser CS, Doudna JA (2006) Structural and mechanistic insights into hepatitis C viral translation initiation. Nature
Reviews Microbiology. [IF=6.979, Cited=140, 17128284].
Batey RT, Doudna JA (1998) The parallel universe of RNA folding. None. [IF=None, Cited=9, 9586989].
Cate JH, Hanna RL, Doudna JA (1997) A magnesium ion core at the heart of a ribozyme domain. None. [IF=None, Cited=174, 9228948].
Kieft JS, Zhou K, Grech A, ..., Doudna JA (2002) Crystal structure of an RNA tertiary domain essential to HCV IRES-
mediated translation initiation. None. [IF=None, Cited=119, 11927953].
Fraser CS, Hershey JWB, Doudna JA (2009) The pathway of hepatitis C virus mRNA recruitment to the human ribosome. Nature
Structural and Molecular Biology. [IF=2.542, Cited=41, 19287397].
Wang HW, Noland C, Siridechadilok B, ..., Nogales E (2009) Structural insights into RNA processing by the human RISC-
loading complex. Nature Structural and Molecular Biology. [IF=2.542, Cited=151, 19820710].
Jinek M, Fabian MR, Coyle SM, ..., Doudna JA (2010) Structural insights into the human GW182-PABC interaction in
microRNA-mediated deadenylation. Nature Structural and Molecular Biology. [IF=2.542, Cited=72, 20098421].
Jore MM, Lundgren M, van Duijn E, ..., Brouns SJJ (2011) Structural basis for CRISPR RNA-guided DNA recognition by
Cascade. Nature Structural and Molecular Biology. [IF=2.542, Cited=350, 21460843].
Sashital DG, Jinek M, Doudna JA (2011) An RNA-induced conformational change required for CRISPR RNA cleavage by the
endoribonuclease Cse3. Nature Structural and Molecular Biology. [IF=2.542, Cited=117, 21572442].
Taylor DW, Ma E, Shigematsu H, ..., Wang HW (2013) Substrate-specific structural rearrangements of human Dicer. Nature
Structural and Molecular Biology. [IF=2.542, Cited=63, 23624860].
Kidwell MA, Doudna JA (2013) Activating silent argonautes. Nature Structural and Molecular Biology. [IF=2.542, Cited=1, 23984440].
Spanggord RJ, Siu F, Ke A, Doudna JA (2005) RNA-mediated interaction between the peptide-binding and GTPase domains of
the signal recognition particle. Nature Structural and Molecular Biology. [IF=2.542, Cited=32, 16299512].
MacRae IJ, Zhou K, Doudna JA (2007) Structural determinants of RNA recognition and cleavage by Dicer. Nature Structural
and Molecular Biology. [IF=2.542, Cited=179, 17873886].
Fraser CS, Lee JY, Mayeur GL, ..., Hershey JWB (2003) The j-subunit of human translation initiation factor eIF3 is
required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro. Journal of Biological
Chemistry. [IF=1.122, Cited=77, 14688252].
van Duijn E, Barbu IM, Barendregt A, ..., Heck AJR (2012) Native tandem and ion mobility mass spectrometry highlight
structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated
protein complexes from Escherichia coli and Pseudomonas aeruginosa. Molecular and Cellular Proteomics. [IF=1.296,
Cited=55, 22918228].
Damoc E, Fraser CS, Zhou M, ..., Leary JA (2007) Structural characterization of the human eukaryotic initiation factor 3
protein complex by mass spectrometry. Molecular and Cellular Proteomics. [IF=1.296, Cited=87, 17322308].
Angrist M, Barrangou R, Baylis F, ..., Davies K (2020) Reactions to the National Academies/Royal Society Report on
Heritable Human Genome Editing. CRISPR Journal. [IF=0.697, Cited=7, 33095048].
Ferré-D'Amaré AR, Doudna JA (1996) Use of cis- and trans-ribozymes to remove 5' and 3' heterogeneities from milligrams
of in vitro transcribed RNA. Nucleic Acids Research. [IF=4.663, Cited=100, 8600468].
Lupták A, Doudna JA (2004) Distinct sites of phosphorothioate substitution interfere with folding and splicing of the
Anabaena group I intron. Nucleic Acids Research. [IF=4.663, Cited=8, 15107495].
Mortimer SA, Doudna JA (2013) Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA
structure. Nucleic Acids Research. [IF=4.663, Cited=58, 23416544].
Lee HY, Zhou K, Smith AM, ..., Doudna JA (2013) Differential roles of human Dicer-binding proteins TRBP and PACT in
small RNA processing. Nucleic Acids Research. [IF=4.663, Cited=125, 23661684].
Sun C, Querol-Audí J, Mortimer SA, ..., Cate JHD (2013) Two RNA-binding motifs in eIF3 direct HCV IRES-dependent
translation. Nucleic Acids Research. [IF=4.663, Cited=54, 23766293].
Bai Y, Zhou K, Doudna JA (2013) Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the
host translation machinery. Nucleic Acids Research. [IF=4.663, Cited=45, 23783572].
Niewoehner O, Jinek M, Doudna JA (2013) Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Nucleic Acids Research. [IF=4.663, Cited=48, 24150936].
Taha TY, Chen IP, Hayashi JM, ..., Ott M (2023) Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron
BA.1 variant through NSP6. None. [IF=None, Cited=0, 36798416].
Yoon PH, Skopintsev P, Shi H, ..., Doudna JA (2023) Eukaryotic RNA-guided endonucleases evolved from a unique clade of
bacterial enzymes. None. [IF=None, Cited=0, 37609353].
Chen K, Han H, Zhao S, ..., Doudna JA (2023) Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-
Cas9 RNP. None. [IF=None, Cited=0, 38014175].
Chen K, Stahl EC, Kang MH, ..., Doudna JA (2023) Engineering self-deliverable ribonucleoproteins for genome editing in
the brain. None. [IF=None, Cited=0, 38014180].
Eggers AR, Chen K, Soczek KM, ..., Doudna JA (2023) Rapid DNA unwinding accelerates genome editing by engineered CRISPR-
Cas9. None. [IF=None, Cited=0, 38168238].
Morgan CJ, Enustun E, Armbruster EG, ..., Pogliano J (2024) An essential and highly selective protein import pathway
encoded by nucleus-forming phage. None. [IF=None, Cited=0, 38562762].
Kieft JS, Grech A, Adams P, Doudna JA (2001) Mechanisms of internal ribosome entry in translation initiation. Cold
Spring Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=8, 12762029].
Macrae IJ, Li F, Zhou K, ..., Doudna JA (2006) Structure of Dicer and mechanistic implications for RNAi. Cold Spring
Harbor Symposia on Quantitative Biology. [IF=0.889, Cited=60, 17381283].
MacRae IJ, Doudna JA (2007) An unusual case of pseudo-merohedral twinning in orthorhombic crystals of Dicer. None.
[IF=None, Cited=10, 17704568].
Jones JT, Barnes CL, Lietzke SE, ..., Kundrot CE (1996) Preliminary X-ray diffraction studies of an RNA pseudoknot that
inhibits HIV-1 reverse transcriptase. None. [IF=None, Cited=1, 15299613].
Yu Y, Ji H, Doudna JA, Leary JA (2005) Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV
IRES-bound complexes. Protein Science. [IF=1.97, Cited=66, 15883184].
Berry KE, Peng B, Koditek D, ..., Shih Ih (2011) Optimized high-throughput screen for hepatitis C virus translation
inhibitors. None. [IF=None, Cited=8, 21297107].
Sternberg SH, Haurwitz RE, Doudna JA (2012) Mechanism of substrate selection by a highly specific CRISPR
endoribonuclease. RNA. [IF=0.956, Cited=102, 22345129].
Lee HY, Doudna JA (2012) TRBP alters human precursor microRNA processing in vitro. RNA. [IF=0.956, Cited=83, 23006623].
Noland CL, Doudna JA (2013) Multiple sensors ensure guide strand selection in human RNAi pathways. RNA. [IF=0.956,
Cited=79, 23531496].
Cox EM, Sagan SM, Mortimer SAW, ..., Sarnow P (2013) Enhancement of hepatitis C viral RNA abundance by precursor miR-122
molecules. RNA. [IF=0.956, Cited=11, 24106328].
Siu FY, Spanggord RJ, Doudna JA (2006) SRP RNA provides the physiologically essential GTPase activation function in
cotranslational protein targeting. RNA. [IF=0.956, Cited=37, 17164479].
Chen L, Lullo DJ, Ma E, ..., Doudna JA (2005) Identification and analysis of U5 snRNA variants in Drosophila. RNA.
[IF=0.956, Cited=16, 16199758].
Chmiel NH, Rio DC, Doudna JA (2006) Distinct contributions of KH domains to substrate binding affinity of Drosophila
P-element somatic inhibitor protein. RNA. [IF=0.956, Cited=25, 16428607].
Berry KE, Waghray S, Doudna JA (2010) The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal
subunit. RNA. [IF=0.956, Cited=58, 20584896].
Sagar MB, Lucast L, Doudna JA (2004) Conserved but nonessential interaction of SRP RNA with translation factor EF-G.
RNA. [IF=0.956, Cited=6, 15100432].
Lintner NG, McClure KF, Petersen D, ..., Cate JHD (2018) Correction: Selective stalling of human translation through
small-molecule engagement of the ribosome nascent chain. PLoS Biology. [IF=2.285, Cited=0, 29664898].
Clarkson BK, Gilbert WV, Doudna JA (2010) Functional overlap between eIF4G isoforms in Saccharomyces cerevisiae. PLoS
ONE. [IF=1.253, Cited=42, 20161741].
Liu TY, Iavarone AT, Doudna JA (2017) Correction: RNA and DNA Targeting by a Reconstituted Thermus thermophilus Type
III-A CRISPR-Cas System. PLoS ONE. [IF=1.253, Cited=0, 28384323].
Ferré-d'Amaré AR, Doudna JA (1997) Establishing suitability of RNA preparations for crystallization. Determination of
polydispersity. Methods in Molecular Biology. [IF=0.413, Cited=3, 9204452].
Cate JH, Doudna JA (1997) A sparse matrix approach to crystallizing ribozymes and RNA motifs. Methods in Molecular
Biology. [IF=0.413, Cited=1, 9204453].

Doudna, Jennifer A

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