Alto, Neal M

Publication with MATCHING institution:

Hansen JM, de Jong MF, Wu Q, ..., Alto NM (2021) Pathogenic ubiquitination of GSDMB inhibits NK cell bactericidal
functions. Cell. [IF=8.479, Cited=71, 34022140].
Selyunin AS, Reddick LE, Weigele BA, Alto NM (2014) Selective protection of an ARF1-GTP signaling axis by a bacterial
scaffold induces bidirectional trafficking arrest. Cell Reports. [IF=1.738, Cited=22, 24582959].
Dobbs N, Burnaevskiy N, Chen D, ..., Yan N (2015) STING Activation by Translocation from the ER Is Associated with
Infection and Autoinflammatory Disease. None. [IF=None, Cited=283, 26235147].
Chen D, Burford WB, Pham G, ..., Alto NM (2021) Systematic reconstruction of an effector-gene network reveals
determinants of Salmonella cellular and tissue tropism. None. [IF=None, Cited=11, 34536347].
Reddick LE, Alto NM (2014) Bacteria fighting back: how pathogens target and subvert the host innate immune system.
Molecular Cell. [IF=2.773, Cited=119, 24766896].
Burnaevskiy N, Peng T, Reddick LE, ..., Alto NM (2015) Myristoylome profiling reveals a concerted mechanism of ARF
GTPase deacylation by the bacterial protease IpaJ. Molecular Cell. [IF=2.773, Cited=39, 25773595].
de Jong MF, Liu Z, Chen D, Alto NM (2016) Shigella flexneri suppresses NF-κB activation by inhibiting linear ubiquitin
chain ligation. Nature Microbiology. [IF=4.448, Cited=52, 27572974].
Weigele BA, Orchard RC, Jimenez A, ..., Alto NM (2017) A systematic exploration of the interactions between bacterial
effector proteins and host cell membranes. Nature Communications. [IF=3.268, Cited=31, 28912547].
Ramirez NGP, Lee J, Zheng Y, ..., D'Orso I (2022) ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-
ERK-AP-1 T cell signaling-transcriptional axis. Nature Communications. [IF=3.268, Cited=3, 35232997].
Yin H, Zheng J, He Q, ..., Zhang H (2023) Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8.
Nature Communications. [IF=3.268, Cited=17, 36599845].
Abrams ME, Johnson KA, Perelman SS, ..., Alto NM (2020) Oxysterols provide innate immunity to bacterial infection by
mobilizing cell surface accessible cholesterol. Nature Microbiology. [IF=4.448, Cited=63, 32284563].
Rex EA, Seo D, Chappidi S, ..., Gammon DB (2024) FEAR antiviral response pathway is independent of interferons and
countered by poxvirus proteins. Nature Microbiology. [IF=4.448, Cited=1, 38538832].
Liu Z, Mar KB, Hanners NW, ..., Alto NM (2019) A NIK-SIX signalling axis controls inflammation by targeted silencing of
non-canonical NF-κB. Nature. [IF=11.591, Cited=29, 30894749].
Miranzadeh Mahabadi H, Lin YCJ, Lin YC, ..., Power C (2024) Monkeypox virus infection of human astrocytes causes
gasdermin B cleavage and pyroptosis. Proceedings of the National Academy of Sciences of the United States of America.
[IF=2.765, Cited=0, 38346199].
Embry A, Baggett NS, Heisler DB, ..., Gammon DB (2024) Exploiting Bacterial Effector Proteins to Uncover Evolutionarily
Conserved Antiviral Host Machinery. None. [IF=None, Cited=0, 38352400].
de Jong MF, Alto NM (2018) Cooperative Immune Suppression by Escherichia coli and Shigella Effector Proteins. Infection
and Immunity. [IF=0.766, Cited=9, 29339461].
Stamm CE, Pasko BL, Chaisavaneeyakorn S, ..., Shiloh MU (2019) Screening Mycobacterium tuberculosis Secreted Proteins
Identifies Mpt64 as a Eukaryotic Membrane-Binding Bacterial Effector. mSphere. [IF=0.941, Cited=15, 31167949].
Jimenez A, Chen D, Alto NM (2016) How Bacteria Subvert Animal Cell Structure and Function. Annual Review of Cell and
Developmental Biology. [IF=2.757, Cited=19, 27146312].
Perelman SS, Abrams ME, Eitson JL, ..., Alto NM (2016) Cell-Based Screen Identifies Human Interferon-Stimulated
Regulators of Listeria monocytogenes Infection. PLoS Pathogens. [IF=1.423, Cited=17, 28002492].
Embry A, Baggett NS, Heisler DB, ..., Gammon DB (2024) Exploiting bacterial effector proteins to uncover evolutionarily
conserved antiviral host machinery. PLoS Pathogens. [IF=1.423, Cited=0, 38753575].
De Jong M, Alto NM (2021) Toxins, mutations and adaptations. eLife. [IF=1.743, Cited=0, 33620030].
Heisler DB, Johnson KA, Ma DH, ..., Radhakrishnan A (2023) A concerted mechanism involving ACAT and SREBPs by which
oxysterols deplete accessible cholesterol to restrict microbial infection. eLife. [IF=1.743, Cited=8, 36695568].

Publication with MISMATCHING institution:

Alto NM, Dixon JE (2008) Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins. None.
[IF=None, Cited=5, 18374161].
Alto NM, Shao F, Lazar CS, ..., Dixon JE (2006) Identification of a bacterial type III effector family with G protein
mimicry functions. Cell. [IF=8.479, Cited=190, 16413487].
Zhang R, Lee DM, Jimah JR, ..., Chen EH (2020) Dynamin regulates the dynamics and mechanical strength of the actin
cytoskeleton as a multifilament actin-bundling protein. Nature Cell Biology. [IF=3.908, Cited=39, 32451441].
Alto NM, Soderling SH, Hoshi N, ..., Scott JD (2003) Bioinformatic design of A-kinase anchoring protein-in silico: a
potent and selective peptide antagonist of type II protein kinase A anchoring. Proceedings of the National Academy of
Sciences of the United States of America. [IF=2.765, Cited=103, 12672969].
Alto NM, Soderling J, Scott JD (2002) Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics.
Journal of Cell Biology. [IF=1.509, Cited=146, 12186851].
Alto NM, Weflen AW, Rardin MJ, ..., Dixon JE (2007) The type III effector EspF coordinates membrane trafficking by the
spatiotemporal activation of two eukaryotic signaling pathways. Journal of Cell Biology. [IF=1.509, Cited=89, 17893247].
Alto NM, Orth K (2012) Subversion of cell signaling by pathogens. Cold Spring Harbor perspectives in biology. [IF=1.926,
Cited=69, 22952390].
Glotfelty LG, Zahs A, Hodges K, ..., Hecht GA (2014) Enteropathogenic E. coli effectors EspG1/G2 disrupt microtubules,
contribute to tight junction perturbation and inhibit restoration. Cellular Microbiology. [IF=0.89, Cited=22, 24948117].
Alto NM (2008) Mimicking small G-proteins: an emerging theme from the bacterial virulence arsenal. Cellular
Microbiology. [IF=0.89, Cited=14, 18190559].
Westphal RS, Tavalin SJ, Lin JW, ..., Scott JD (1999) Regulation of NMDA receptors by an associated phosphatase-kinase
signaling complex. Science. [IF=7.729, Cited=309, 10390370].
Kraiss LW, Weyrich AS, Alto NM, ..., Zimmerman GA (2000) Fluid flow activates a regulator of translation, p70/p85 S6
kinase, in human endothelial cells. American Journal of Physiology - Heart and Circulatory Physiology. [IF=1.161,
Cited=46, 10775131].
Alto NM, Scott JD (2004) The role of A-Kinase anchoring proteins in cAMP-mediated signal transduction pathways. Cell
Biochemistry and Biophysics. [IF=0.723, Cited=5, 15289655].
Rinkenberger N, Abrams ME, Matta SK, ..., Sibley LD (2021) Overexpression screen of interferon-stimulated genes
identifies RARRES3 as a restrictor of Toxoplasma gondii infection. eLife. [IF=1.743, Cited=13, 34871166].

Publication with MISSING institution:

de Jong MF, Alto NM (2014) Thinking outside the Osp(G)--kinase activation by E2-ubiquitin. EMBO Journal. [IF=2.114,
Cited=1, 24480478].
Kraiss LW, Ennis TM, Alto NM (2001) Flow-induced DNA synthesis requires signaling to a translational control pathway.
Journal of Surgical Research. [IF=1.014, Cited=15, 11319875].
Orchard RC, Kittisopikul M, Altschuler SJ, ..., Alto NM (2012) Identification of F-actin as the dynamic hub in a
microbial-induced GTPase polarity circuit. Cell. [IF=8.479, Cited=21, 22341450].
Ohlson MB, Huang Z, Alto NM, ..., Miller SI (2008) Structure and function of Salmonella SifA indicate that its
interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. None. [IF=None, Cited=112, 18996344].
Weigele BA, Alto NM (2010) Salmonella taking charge. None. [IF=None, Cited=3, 20542244].
Mattoo S, Alto NM, Dixon JE (2008) Subversion of myosin function by E. coli. Developmental Cell. [IF=2.256, Cited=3, 18194648].
Navarro L, Alto NM, Dixon JE (2005) Functions of the Yersinia effector proteins in inhibiting host immune responses.
Current Opinion in Microbiology. [IF=1.52, Cited=79, 15694853].
Selyunin AS, Sutton SE, Weigele BA, ..., Alto NM (2010) The assembly of a GTPase-kinase signalling complex by a
bacterial catalytic scaffold. Nature. [IF=11.591, Cited=78, 21170023].
Burnaevskiy N, Fox TG, Plymire DA, ..., Alto NM (2013) Proteolytic elimination of N-myristoyl modifications by the
Shigella virulence factor IpaJ. Nature. [IF=11.591, Cited=96, 23535599].
Huang Z, Sutton SE, Wallenfang AJ, ..., Alto NM (2009) Structural insights into host GTPase isoform selection by a
family of bacterial GEF mimics. Nature Structural and Molecular Biology. [IF=2.542, Cited=95, 19620963].
Kraiss LW, Alto NM, Dixon DA, ..., Zimmerman GA (2003) Fluid flow regulates E-selectin protein levels in human
endothelial cells by inhibiting translation. Journal of Vascular Surgery. [IF=2.095, Cited=19, 12514595].
Bui M, Gilady SY, Fitzsimmons REB, ..., Simmen T (2010) Rab32 modulates apoptosis onset and mitochondria-associated
membrane (MAM) properties. Journal of Biological Chemistry. [IF=1.122, Cited=97, 20670942].
Westphal RS, Soderling SH, Alto NM, ..., Scott JD (2000) Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an
actin-associated multi-kinase scaffold. EMBO Journal. [IF=2.114, Cited=133, 10970852].
Pultz MA, Zimmerman KK, Alto NM, ..., Zehrung DL (2000) A genetic screen for zygotic embryonic lethal mutations
affecting cuticular morphology in the wasp Nasonia vitripennis. Genetics. [IF=1.102, Cited=20, 10866651].
Rex EA, Seo D, Chappidi S, ..., Gammon DB (2023) A FACT-ETS-1 Antiviral Response Pathway Restricts Viral Replication and
is Countered by Poxvirus A51R Proteins. None. [IF=None, Cited=0, 36798356].
Hodges K, Alto NM, Ramaswamy K, ..., Hecht G (2008) The enteropathogenic Escherichia coli effector protein EspF
decreases sodium hydrogen exchanger 3 activity. Cellular Microbiology. [IF=0.89, Cited=45, 18433466].
Weflen AW, Alto NM, Viswanathan VK, Hecht G (2010) E. coli secreted protein F promotes EPEC invasion of intestinal
epithelial cells via an SNX9-dependent mechanism. Cellular Microbiology. [IF=0.89, Cited=25, 20088948].
Orchard RC, Alto NM (2011) Mimicking GEFs: a common theme for bacterial pathogens. Cellular Microbiology. [IF=0.89,
Cited=27, 21951829].
Weflen AW, Alto NM, Hecht GA (2009) Tight junctions and enteropathogenic E. coli. Annals of the New York Academy of
Sciences. [IF=1.878, Cited=14, 19538303].
Pultz MA, Pitt JN, Alto NM (1999) Extensive zygotic control of the anteroposterior axis in the wasp Nasonia vitripennis.
Development (Cambridge). [IF=1.291, Cited=27, 9895318].
Gawthorne JA, Reddick LE, Akpunarlieva SN, ..., Roe AJ (2012) Express your LOV: an engineered flavoprotein as a reporter
for protein expression and purification. PLoS ONE. [IF=1.253, Cited=14, 23300834].
Reddick LE, Alto NM (2012) Correlative light and electron microscopy (CLEM) as a tool to visualize microinjected
molecules and their eukaryotic sub-cellular targets. Journal of Visualized Experiments. [IF=0.398, Cited=7, 22588091].
Selyunin AS, Alto NM (2011) Activation of PAK by a bacterial type III effector EspG reveals alternative mechanisms of
GTPase pathway regulation. Small GTPases. [IF=0.531, Cited=7, 22145094].